PT927184E - Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao - Google Patents

Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao

Info

Publication number
PT927184E
PT927184E PT97940118T PT97940118T PT927184E PT 927184 E PT927184 E PT 927184E PT 97940118 T PT97940118 T PT 97940118T PT 97940118 T PT97940118 T PT 97940118T PT 927184 E PT927184 E PT 927184E
Authority
PT
Portugal
Prior art keywords
enene
substitutes
pyrimidine
derivatives
production
Prior art date
Application number
PT97940118T
Other languages
English (en)
Inventor
Hans-Juergen Teschendorf
Franz Emling
Karsten Wicke
Wilfried Lubisch
Gerd Steiner
Alfred Bach
Berthold Behl
Frank Kerrrigan
Sharon Cheetham
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of PT927184E publication Critical patent/PT927184E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT97940118T 1996-09-10 1997-08-22 Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao PT927184E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19636769A DE19636769A1 (de) 1996-09-10 1996-09-10 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
PT927184E true PT927184E (pt) 2004-03-31

Family

ID=7805168

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97940118T PT927184E (pt) 1996-09-10 1997-08-22 Derivados de pirido-¬4',3':4,5|-tieno-¬2,3-d|-pirimidina 3-substituidos a sua producao e a sua utilizacao

Country Status (32)

Country Link
US (1) US6222034B1 (pt)
EP (1) EP0927184B1 (pt)
JP (1) JP2001500138A (pt)
KR (1) KR20000035987A (pt)
CN (2) CN1230962A (pt)
AR (1) AR009572A1 (pt)
AT (1) ATE252587T1 (pt)
AU (1) AU736678B2 (pt)
BG (1) BG63602B1 (pt)
BR (1) BR9711724A (pt)
CA (1) CA2265509A1 (pt)
CO (1) CO4900071A1 (pt)
CZ (1) CZ288896B6 (pt)
DE (2) DE19636769A1 (pt)
DK (1) DK0927184T3 (pt)
ES (1) ES2210570T3 (pt)
HK (1) HK1043593A1 (pt)
HR (1) HRP970484A2 (pt)
HU (1) HUP9904107A3 (pt)
ID (1) ID18260A (pt)
IL (1) IL128142A0 (pt)
NO (1) NO991132L (pt)
NZ (1) NZ334350A (pt)
PL (1) PL332144A1 (pt)
PT (1) PT927184E (pt)
RU (1) RU2198888C2 (pt)
SK (1) SK283039B6 (pt)
TR (1) TR199900503T2 (pt)
TW (1) TW480264B (pt)
UA (1) UA54449C2 (pt)
WO (1) WO1998011110A1 (pt)
ZA (1) ZA978081B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19724979A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) * 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19734444A1 (de) * 1997-08-08 1999-02-11 Basf Ag 3-Substituierte 3,4,5,7-Tetrahydro-pyrrolo(3',4':4,5) thieno (2,3-d) pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19900545A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
DE19900673A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
FR2791980B1 (fr) * 1999-04-09 2001-07-06 Sod Conseils Rech Applic Pyrido-thieno-diazepines, leur procede de preparation, et les compositions pharmaceutiques les contenant
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
ES2291329T3 (es) * 2000-07-18 2008-03-01 Dainippon Sumitomo Pharma Co., Ltd. Inhibidores de la recaptacion de serotonina.
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
ATE511511T1 (de) * 2003-03-31 2011-06-15 Trovis Pharmaceuticals Llc Neue piperidinylaminothienoä2,3-dü pyrimidinverbindungen
US7612078B2 (en) * 2003-03-31 2009-11-03 Epix Delaware, Inc. Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050222175A1 (en) * 2004-03-31 2005-10-06 Dhanoa Dale S New piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
US7488736B2 (en) * 2004-05-17 2009-02-10 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7598265B2 (en) * 2004-09-30 2009-10-06 Epix Delaware, Inc. Compositions and methods for treating CNS disorders
US7407966B2 (en) * 2004-10-07 2008-08-05 Epix Delaware, Inc. Thienopyridinone compounds and methods of treatment
US7576211B2 (en) * 2004-09-30 2009-08-18 Epix Delaware, Inc. Synthesis of thienopyridinone compounds and related intermediates
EP2445877B1 (en) * 2008-12-03 2014-07-23 Nanotherapeutics, Inc. Bicyclic compounds and methods of making and using same
ES2605005T3 (es) * 2010-04-14 2017-03-10 Bayer Intellectual Property Gmbh Procedimiento para la preparación de ditiino-tetracarboximidas

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272088C (pt) *
DE272086C (pt) *
DE272079C (pt) *
DE1937459A1 (de) * 1968-08-02 1970-02-05 Ciba Geigy Neue Pyrimidinderivate und Verfahren zu ihrer Herstellung
US3823151A (en) * 1968-08-02 1974-07-09 Ciba Geigy Corp 4,5,6,7-tetrahydrothieno(2,3-d)pyridines
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩
WO1987004928A1 (en) * 1986-02-24 1987-08-27 Mitsui Petrochemical Industries, Ltd. Agents for treating neurophathy
US5001130A (en) 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4835157A (en) * 1988-03-15 1989-05-30 Ortho Pharmaceutical Corporation Thieno- and furopyrimidine-2,4-dione piperidine derivatives as serotonin antagonists and alpha adrenergic blocking agents

Also Published As

Publication number Publication date
SK23099A3 (en) 1999-08-06
PL332144A1 (en) 1999-08-30
KR20000035987A (ko) 2000-06-26
JP2001500138A (ja) 2001-01-09
CO4900071A1 (es) 2000-03-27
ES2210570T3 (es) 2004-07-01
RU2198888C2 (ru) 2003-02-20
TW480264B (en) 2002-03-21
CN1332168A (zh) 2002-01-23
CA2265509A1 (en) 1998-03-19
US6222034B1 (en) 2001-04-24
WO1998011110A1 (de) 1998-03-19
CN1230962A (zh) 1999-10-06
NZ334350A (en) 2000-07-28
BG103122A (en) 1999-09-30
BR9711724A (pt) 1999-08-24
NO991132D0 (no) 1999-03-09
TR199900503T2 (xx) 1999-07-21
CZ288896B6 (cs) 2001-09-12
ZA978081B (en) 1999-03-09
BG63602B1 (bg) 2002-06-28
AU4207197A (en) 1998-04-02
HK1043593A1 (zh) 2002-09-20
EP0927184A1 (de) 1999-07-07
ID18260A (id) 1998-03-19
HRP970484A2 (en) 1998-10-31
ATE252587T1 (de) 2003-11-15
HUP9904107A3 (en) 2001-10-29
IL128142A0 (en) 1999-11-30
DK0927184T3 (da) 2004-03-01
DE59710902D1 (de) 2003-11-27
AU736678B2 (en) 2001-08-02
HUP9904107A2 (hu) 2000-05-28
UA54449C2 (uk) 2003-03-17
DE19636769A1 (de) 1998-03-12
EP0927184B1 (de) 2003-10-22
AR009572A1 (es) 2000-04-26
CZ75999A3 (cs) 1999-06-16
NO991132L (no) 1999-03-09
SK283039B6 (sk) 2003-02-04

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