NO964700L - Nye aminosyrederivater, fremgangsmåte til deres fremstilling og farmasöytiske blandinger som inneholder disse forbindelser - Google Patents

Nye aminosyrederivater, fremgangsmåte til deres fremstilling og farmasöytiske blandinger som inneholder disse forbindelser

Info

Publication number
NO964700L
NO964700L NO964700A NO964700A NO964700L NO 964700 L NO964700 L NO 964700L NO 964700 A NO964700 A NO 964700A NO 964700 A NO964700 A NO 964700A NO 964700 L NO964700 L NO 964700L
Authority
NO
Norway
Prior art keywords
preparation
amino acid
acid derivatives
compounds
processes
Prior art date
Application number
NO964700A
Other languages
English (en)
Other versions
NO964700D0 (no
Inventor
Gerd Schnorrenberg
Franz Esser
Horst Dollinger
Birgit Jung
Georg Speck
Erich Buerger
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4445939A external-priority patent/DE4445939A1/de
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO964700D0 publication Critical patent/NO964700D0/no
Publication of NO964700L publication Critical patent/NO964700L/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Denne oppfinnelse vedrører nye aminosyrederivater med den generelle formel I R1 - R11 - A1 - B (D og deres farmasøytisk aksepterbare salter, hvor gruppe B er - A2 - NR2R3 eller R5, hvor R,A,A,R,R,R og R har den betydning som er angitt i beskrivelsen, samt deres fremstilling og anvendelse. De nye forbindelser er verdifulle neurokinin (Tachykinin)-antagonister.
NO964700A 1994-05-07 1996-11-06 Nye aminosyrederivater, fremgangsmåte til deres fremstilling og farmasöytiske blandinger som inneholder disse forbindelser NO964700L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4416255 1994-05-07
DE4445939A DE4445939A1 (de) 1994-05-07 1994-12-22 Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen (II)
PCT/EP1995/001691 WO1995030687A1 (de) 1994-05-07 1995-05-04 Neurokinin (tachykinin)-antagonisten

Publications (2)

Publication Number Publication Date
NO964700D0 NO964700D0 (no) 1996-11-06
NO964700L true NO964700L (no) 1996-11-06

Family

ID=25936418

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964700A NO964700L (no) 1994-05-07 1996-11-06 Nye aminosyrederivater, fremgangsmåte til deres fremstilling og farmasöytiske blandinger som inneholder disse forbindelser

Country Status (20)

Country Link
US (2) US5712273A (no)
EP (1) EP0804463A1 (no)
JP (1) JPH09512806A (no)
CN (1) CN1147260A (no)
AU (1) AU690275B2 (no)
BG (1) BG100946A (no)
CA (1) CA2189764A1 (no)
CZ (1) CZ325496A3 (no)
EE (1) EE9600186A (no)
FI (1) FI964473A0 (no)
HR (1) HRP950276A2 (no)
HU (1) HUT75708A (no)
IL (1) IL113625A0 (no)
MX (1) MX9605128A (no)
NO (1) NO964700L (no)
NZ (1) NZ285750A (no)
PL (1) PL317127A1 (no)
RO (1) RO115355B1 (no)
SK (1) SK142696A3 (no)
WO (1) WO1995030687A1 (no)

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DE19623950A1 (de) * 1996-06-15 1997-12-18 Boehringer Ingelheim Kg Pharmazeutische Zubereitung in Form von Liposomen
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US7125840B2 (en) * 2001-10-09 2006-10-24 Eli Lilly And Company Substituted dipeptides as growth hormone secretagogues
US7396846B2 (en) * 2002-04-09 2008-07-08 Eli Lilly And Company Growth hormone secretagogues
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GB9023116D0 (en) * 1990-10-24 1990-12-05 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
ES2137998T3 (es) * 1992-09-03 2000-01-01 Boehringer Ingelheim Pharma Nuevos derivados de aminoacidos, procedimiento para su preparacion y composiciones farmaceuticas que contienen estos compuestos.

Also Published As

Publication number Publication date
FI964473A (fi) 1996-11-07
RO115355B1 (ro) 2000-01-28
SK142696A3 (en) 1997-06-04
HRP950276A2 (en) 1997-04-30
US5712273A (en) 1998-01-27
NO964700D0 (no) 1996-11-06
AU2524995A (en) 1995-11-29
HUT75708A (en) 1997-05-28
PL317127A1 (en) 1997-03-17
BG100946A (en) 1997-07-31
EE9600186A (et) 1997-08-15
FI964473A0 (fi) 1996-11-07
CN1147260A (zh) 1997-04-09
CZ325496A3 (en) 1997-09-17
US5700827A (en) 1997-12-23
CA2189764A1 (en) 1995-11-16
IL113625A0 (en) 1995-08-31
NZ285750A (en) 1998-08-26
JPH09512806A (ja) 1997-12-22
MX9605128A (es) 1997-08-30
AU690275B2 (en) 1998-04-23
HU9603082D0 (en) 1997-01-28
WO1995030687A1 (de) 1995-11-16
EP0804463A1 (de) 1997-11-05

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