NO960177L - Fremgangsmåte for fremstilling av sakaridsammensetninger - Google Patents
Fremgangsmåte for fremstilling av sakaridsammensetningerInfo
- Publication number
- NO960177L NO960177L NO960177A NO960177A NO960177L NO 960177 L NO960177 L NO 960177L NO 960177 A NO960177 A NO 960177A NO 960177 A NO960177 A NO 960177A NO 960177 L NO960177 L NO 960177L
- Authority
- NO
- Norway
- Prior art keywords
- saccharide compositions
- acceptor moiety
- preparing
- saccharide
- preparing saccharide
- Prior art date
Links
- 150000001720 carbohydrates Chemical class 0.000 title abstract 5
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 1
- 229930186217 Glycolipid Natural products 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 102000051366 Glycosyltransferases Human genes 0.000 abstract 1
- 108700023372 Glycosyltransferases Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9137293A | 1993-07-15 | 1993-07-15 | |
PCT/US1994/007807 WO1995002683A1 (fr) | 1993-07-15 | 1994-07-15 | Procede de synthese de compositions de saccharide |
Publications (2)
Publication Number | Publication Date |
---|---|
NO960177D0 NO960177D0 (no) | 1996-01-15 |
NO960177L true NO960177L (no) | 1996-03-07 |
Family
ID=22227422
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO960177A NO960177L (no) | 1993-07-15 | 1996-01-15 | Fremgangsmåte for fremstilling av sakaridsammensetninger |
Country Status (9)
Country | Link |
---|---|
US (2) | US5879912A (fr) |
EP (1) | EP0785988A1 (fr) |
JP (1) | JPH09503905A (fr) |
CN (1) | CN1129953A (fr) |
AU (1) | AU691510B2 (fr) |
CA (1) | CA2167157A1 (fr) |
FI (1) | FI960173A (fr) |
NO (1) | NO960177L (fr) |
WO (1) | WO1995002683A1 (fr) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100556051B1 (ko) * | 1996-09-13 | 2006-05-23 | 교와 핫꼬 고교 가부시끼가이샤 | 당뉴클레오티드류및복합당질의제조방법 |
CA2237849C (fr) * | 1996-09-17 | 2009-06-16 | Kyowa Hakko Kogyo Co., Ltd. | Procedes de production de nucleotides de sucre et de glucides complexes |
KR100490507B1 (ko) | 1996-10-10 | 2005-05-19 | 네오스 테크놀로지스, 인크. | 한외 여과, 역 삼투 및 나노 여과를 사용하는 탄수화물의 정제 |
US6045854A (en) * | 1997-03-31 | 2000-04-04 | Abbott Laboraties | Nutritional formulations containing oligosaccharides |
US5945314A (en) * | 1997-03-31 | 1999-08-31 | Abbott Laboratories | Process for synthesizing oligosaccharides |
DE19716731A1 (de) * | 1997-04-14 | 1998-10-15 | Biopract Gmbh | Verfahren zur enzymatischen Herstellung von Fructosylverbindungen |
US7060469B2 (en) * | 1998-04-02 | 2006-06-13 | The Board Of Regents Of The University Of Oklahoma | Polymer grafting by polysaccharide synthases |
US20060105431A1 (en) * | 1998-11-11 | 2006-05-18 | Deangelis Paul L | Polymer grafting by polysaccharide synthases using artificial sugar acceptors |
JP2002529064A (ja) * | 1998-11-11 | 2002-09-10 | ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティー オブ オクラホマ | 多糖類シンターゼによるポリマーグラフティング |
DK2264177T3 (en) * | 1998-12-09 | 2016-01-11 | Phyton Holdings Llc | Glycoproteins with human-type glycosylation |
US6699705B2 (en) * | 1999-02-01 | 2004-03-02 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
US20010051349A1 (en) | 2000-02-17 | 2001-12-13 | Glycominds Ltd. | Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof |
AU5407300A (en) * | 1999-06-30 | 2001-01-22 | Novartis Ag | Ophthalmic molding |
FR2796082B1 (fr) * | 1999-07-07 | 2003-06-27 | Centre Nat Rech Scient | Procede de production d'oligosaccharides |
EP1772518B1 (fr) | 1999-10-26 | 2010-08-18 | Stichting Dienst Landbouwkundig Onderzoek | Mammifère glycosylation dans des plantes |
US7534589B2 (en) * | 1999-11-10 | 2009-05-19 | The Board Of Regents Of The University Of Oklahoma | Polymer grafting by polysaccharide synthases |
US20020132320A1 (en) * | 2001-01-10 | 2002-09-19 | Wang Peng George | Glycoconjugate synthesis using a pathway-engineered organism |
ZA200306406B (en) | 2001-01-19 | 2004-09-06 | Dow Chemical Co | Method for secretory production of glycoprotein having human-type sugar chain using plant cell. |
WO2002070672A2 (fr) * | 2001-03-06 | 2002-09-12 | The Dow Chemical Company | Cellule vegetale comportant une fonction d'addition de chaine de sucres de type animal |
NZ531139A (en) | 2001-08-29 | 2007-09-28 | Neose Technologies Inc | Synthetic ganglioside derivatives and compositions thereof |
US20030096281A1 (en) * | 2001-09-14 | 2003-05-22 | Ganesh Venkataraman | Methods of making glycomolecules with enhanced activities and uses thereof |
US20040214228A9 (en) * | 2001-09-14 | 2004-10-28 | Ganesh Venkataraman | Methods of evaluating glycomolecules for enhanced activities |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
SG159381A1 (en) * | 2001-10-10 | 2010-03-30 | Novo Nordisk As | Remodeling and glycoconjugation of peptides |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
KR100527437B1 (ko) * | 2001-11-20 | 2005-11-09 | 한국생명공학연구원 | β-1,4-갈락토실트랜스퍼라제의 생산방법 |
US20030166866A1 (en) * | 2002-01-28 | 2003-09-04 | Land O' Lakes, Inc. | Method of processing a proteinaceous material to recover K-casein macropeptide and polymers of a-lactalbumin and B-lactoglobulin |
JP4048289B2 (ja) * | 2002-02-26 | 2008-02-20 | 独立行政法人科学技術振興機構 | 微細自己集合体 |
JP4052553B2 (ja) * | 2002-03-07 | 2008-02-27 | 独立行政法人科学技術振興機構 | 微細自己集合体の製法 |
JP5350573B2 (ja) | 2002-03-19 | 2013-11-27 | スティヒティング ディーンスト ランドバウクンディフ オンデルズーク | 植物におけるgntiii発現 |
EP1485486B1 (fr) | 2002-03-19 | 2012-11-21 | Stichting Dienst Landbouwkundig Onderzoek | Optimisation du traitement du glycane chez les plantes |
CL2003002461A1 (es) | 2002-11-27 | 2005-01-07 | Dow Chemical Company Agroscien | Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas. |
JP2006515927A (ja) * | 2002-12-20 | 2006-06-08 | モメンタ ファーマシューティカルズ インコーポレイテッド | 疾患を診断および監視するためのグリカンマーカー |
JP4405736B2 (ja) | 2003-01-31 | 2010-01-27 | コニカミノルタホールディングス株式会社 | データベースシステム |
JP2004261885A (ja) * | 2003-02-18 | 2004-09-24 | Japan Science & Technology Agency | 有機ナノチューブへ機能性物質を導入する方法 |
CA2518171C (fr) | 2003-03-06 | 2013-07-09 | Neose Technologies, Inc. | Procedes et compositions pour la synthese enzymatique de gangliosides |
MXPA05010773A (es) | 2003-04-09 | 2005-12-12 | Neose Technologies Inc | Metodos de glicopegilacion y proteinas/peptidos producidos por los metodos. |
WO2005012484A2 (fr) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Conjugues anticorps-toxines |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
EP1814573B1 (fr) | 2004-10-29 | 2016-03-09 | ratiopharm GmbH | Remodelage et glycopegylation du facteur de croissance des fibroblastes (fgf) |
JP4951527B2 (ja) | 2005-01-10 | 2012-06-13 | バイオジェネリックス アーゲー | 糖peg化顆粒球コロニー刺激因子 |
EP2386571B1 (fr) | 2005-04-08 | 2016-06-01 | ratiopharm GmbH | Compositions et méthodes utilisées pour la préparation de mutants par glycosylation de l'hormone de croissance humaine résistant à la protéase |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
JP2006143723A (ja) * | 2005-11-16 | 2006-06-08 | Japan Science & Technology Agency | 微細自己集合体 |
EP2049144B8 (fr) | 2006-07-21 | 2015-02-18 | ratiopharm GmbH | Glycosylation de peptides par l'intermédiaire de séquences de glycosylation à liaison o |
JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
EP2144923B1 (fr) | 2007-04-03 | 2013-02-13 | BioGeneriX AG | Méthodes de traitement à l'aide d'un facteur g-csf glycopégylé |
CA2682738A1 (fr) * | 2007-04-16 | 2008-10-23 | Momenta Pharmaceuticals, Inc. | Produits de glycoproteines definis et procedes associes |
MX341988B (es) | 2007-04-17 | 2016-09-08 | Stichting Dienst Landbouwkunding Onderzoek | Glicosilacion tipo mamifera en plantas para la expresion de glicosil-transferasas no mamiferas. |
WO2008154639A2 (fr) | 2007-06-12 | 2008-12-18 | Neose Technologies, Inc. | Procédé amélioré pour la production de sucres de nucléotide |
EP3175857A1 (fr) | 2009-03-25 | 2017-06-07 | Seneb Biosciences Inc. | Glycolipides en tant que traitement de maladies |
CN102869784A (zh) | 2010-04-07 | 2013-01-09 | 动量制药公司 | 高甘露糖聚糖 |
BR122021005283B1 (pt) | 2010-06-02 | 2022-02-22 | Evolva, Inc | Hospedeiro recombinante que compreende genes recombinantes para produção deesteviol ou glicosídeo de esteviol, método para produzir esteviol, glicosídeo de esteviol ou composição de glicosídeo de esteviol e método para sintetizar esteviol ou glicosídeo de esteviol |
EP2686671A4 (fr) | 2011-03-12 | 2015-06-24 | Momenta Pharmaceuticals Inc | N-glycanes contenant de la n-acétylhexosamine dans des produits de glycoprotéines |
ES2671555T3 (es) | 2011-06-07 | 2018-06-07 | Hero Ag | Obtención de oligosacáridos mediante un proceso biotecnológico |
SG10201606565XA (en) | 2011-08-08 | 2016-10-28 | Evolva Sa | Recombinant production of steviol glycosides |
WO2013181575A2 (fr) | 2012-06-01 | 2013-12-05 | Momenta Pharmaceuticals, Inc. | Méthodes associées au denosumab |
EP2954058B1 (fr) | 2013-02-06 | 2021-03-31 | Evolva SA | Procédés pour la production améliorée de rébaudioside d et de rébaudioside m |
MX2015010098A (es) | 2013-02-11 | 2016-04-19 | Evolva Sa | Producción eficiente de glicosidos de esteviol en huéspedes recombinantes. |
EP2855533A4 (fr) | 2013-03-15 | 2015-11-25 | Momenta Pharmaceuticals Inc | Procédés se rapportant à des protéines de fusion fc-ctla4 |
US10464996B2 (en) | 2013-05-13 | 2019-11-05 | Momenta Pharmaceuticals, Inc. | Methods for the treatment of neurodegeneration |
WO2015057622A1 (fr) | 2013-10-16 | 2015-04-23 | Momenta Pharmaceuticals, Inc. | Glycoprotéines sialylées |
BR112017002783A2 (pt) | 2014-08-11 | 2017-12-19 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
CN107109358B (zh) | 2014-09-09 | 2022-08-02 | 埃沃尔瓦公司 | 在重组宿主中生产甜菊醇糖苷 |
US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
WO2016120486A1 (fr) | 2015-01-30 | 2016-08-04 | Evolva Sa | Production de glycosides de stéviol dans des hôtes de recombinaison |
BR112017019625A2 (pt) | 2015-03-16 | 2018-05-08 | Dsm Ip Assets Bv | udp-glicosiltransferases |
US10837041B2 (en) | 2015-08-07 | 2020-11-17 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
SG11201808856TA (en) | 2016-04-13 | 2018-11-29 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
WO2017182965A1 (fr) | 2016-04-19 | 2017-10-26 | Glycom A/S | Séparation d'oligosaccharides d'un bouillon de fermentation |
WO2017198682A1 (fr) | 2016-05-16 | 2017-11-23 | Evolva Sa | Production de glycosides de stéviol dans des hôtes de recombinaison |
WO2018083338A1 (fr) | 2016-11-07 | 2018-05-11 | Evolva Sa | Production de glycosides de stéviol dans des hôtes recombinants |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58149697A (ja) * | 1982-02-27 | 1983-09-06 | Dainippon Ink & Chem Inc | β−1,3グリコシルステビオシドの製造方法 |
US5135854A (en) * | 1987-10-29 | 1992-08-04 | Zymogenetics, Inc. | Methods of regulating protein glycosylation |
FR2626583B1 (fr) * | 1988-01-29 | 1991-03-15 | Bioeurope | Procede de preparation enzymatique d'oligodextranes utiles dans la fabrication de substituts du sucre, et nouveaux oligodextranes |
US5047335A (en) * | 1988-12-21 | 1991-09-10 | The Regents Of The University Of Calif. | Process for controlling intracellular glycosylation of proteins |
FR2640997A1 (en) * | 1988-12-22 | 1990-06-29 | Ajinomoto Kk | Process for the manufacture of a galactose transfer product. |
US5032519A (en) * | 1989-10-24 | 1991-07-16 | The Regents Of The Univ. Of California | Method for producing secretable glycosyltransferases and other Golgi processing enzymes |
US5324663A (en) * | 1990-02-14 | 1994-06-28 | The Regents Of The University Of Michigan | Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures |
US5180674A (en) * | 1990-04-16 | 1993-01-19 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
US5348867A (en) * | 1991-11-15 | 1994-09-20 | George Georgiou | Expression of proteins on bacterial surface |
US5545553A (en) * | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
-
1994
- 1994-07-15 AU AU73299/94A patent/AU691510B2/en not_active Ceased
- 1994-07-15 CA CA002167157A patent/CA2167157A1/fr not_active Abandoned
- 1994-07-15 WO PCT/US1994/007807 patent/WO1995002683A1/fr not_active Application Discontinuation
- 1994-07-15 JP JP7504666A patent/JPH09503905A/ja active Pending
- 1994-07-15 CN CN94193208A patent/CN1129953A/zh active Pending
- 1994-07-15 EP EP94923435A patent/EP0785988A1/fr not_active Withdrawn
-
1996
- 1996-01-15 FI FI960173A patent/FI960173A/fi unknown
- 1996-01-15 NO NO960177A patent/NO960177L/no not_active Application Discontinuation
- 1996-06-17 US US08/664,882 patent/US5879912A/en not_active Expired - Fee Related
-
1999
- 1999-03-09 US US09/265,067 patent/US6284493B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU7329994A (en) | 1995-02-13 |
CN1129953A (zh) | 1996-08-28 |
EP0785988A4 (fr) | 1997-07-30 |
EP0785988A1 (fr) | 1997-07-30 |
WO1995002683A1 (fr) | 1995-01-26 |
FI960173A (fi) | 1996-03-15 |
AU691510B2 (en) | 1998-05-21 |
CA2167157A1 (fr) | 1995-01-26 |
FI960173A0 (fi) | 1996-01-15 |
NO960177D0 (no) | 1996-01-15 |
US5879912A (en) | 1999-03-09 |
US6284493B1 (en) | 2001-09-04 |
JPH09503905A (ja) | 1997-04-22 |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |