NO952264D0 - Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende taxoidene - Google Patents

Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende taxoidene

Info

Publication number
NO952264D0
NO952264D0 NO952264A NO952264A NO952264D0 NO 952264 D0 NO952264 D0 NO 952264D0 NO 952264 A NO952264 A NO 952264A NO 952264 A NO952264 A NO 952264A NO 952264 D0 NO952264 D0 NO 952264D0
Authority
NO
Norway
Prior art keywords
sub
taxoids
radical
preparation
new
Prior art date
Application number
NO952264A
Other languages
English (en)
Other versions
NO310555B1 (no
NO952264L (no
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9436375&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO952264(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO952264L publication Critical patent/NO952264L/no
Publication of NO952264D0 publication Critical patent/NO952264D0/no
Publication of NO310555B1 publication Critical patent/NO310555B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO19952264A 1992-12-09 1995-06-08 Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende taxoidene NO310555B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9214813A FR2698871B1 (fr) 1992-12-09 1992-12-09 Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1993/001201 WO1994013654A1 (fr) 1992-12-09 1993-12-07 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number Publication Date
NO952264L NO952264L (no) 1995-06-08
NO952264D0 true NO952264D0 (no) 1995-06-08
NO310555B1 NO310555B1 (no) 2001-07-23

Family

ID=9436375

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19952264A NO310555B1 (no) 1992-12-09 1995-06-08 Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende taxoidene

Country Status (30)

Country Link
US (9) US7074821B1 (no)
EP (1) EP0673372B1 (no)
JP (2) JP2785248B2 (no)
KR (1) KR100346328B1 (no)
CN (1) CN1055467C (no)
AT (1) ATE243688T1 (no)
AU (2) AU685415B2 (no)
BG (1) BG61726B1 (no)
BR (1) BR9307613A (no)
CA (1) CA2150944C (no)
CZ (1) CZ289851B6 (no)
DE (1) DE69333064T2 (no)
DK (1) DK0673372T3 (no)
ES (1) ES2202319T3 (no)
FI (1) FI110941B (no)
FR (1) FR2698871B1 (no)
HU (1) HU227872B1 (no)
MX (1) MX9307748A (no)
NO (1) NO310555B1 (no)
NZ (1) NZ258592A (no)
OA (1) OA10166A (no)
PL (3) PL175539B1 (no)
PT (1) PT673372E (no)
RO (1) RO112281B1 (no)
RU (1) RU2139864C1 (no)
SG (1) SG67338A1 (no)
SK (1) SK282139B6 (no)
TW (1) TW408120B (no)
UA (1) UA51612C2 (no)
WO (1) WO1994013654A1 (no)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696460B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2697752B1 (fr) 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
FR2698361B1 (fr) * 1992-11-20 1995-01-13 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5.
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5814658A (en) * 1992-12-09 1998-09-29 Rhone-Poulenc Rorer S.A. Taxoids, their preparation and pharmaceutical compositions containing them
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
EP0703909B1 (en) * 1993-06-11 2000-04-26 PHARMACIA & UPJOHN COMPANY Delta 6,7 -taxols antineoplastic use and pharmaceutical compositions containing them
FR2706457B1 (fr) * 1993-06-16 1995-07-28 Rhone Poulenc Rorer Sa Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs.
FR2712288B1 (fr) * 1993-11-08 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
IL127598A (en) * 1994-01-28 2003-04-10 Upjohn Co Process for preparing isotaxol analogs
FR2721024B1 (fr) * 1994-06-09 1996-07-12 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2721023B1 (fr) * 1994-06-09 1996-07-12 Rhone Poulenc Rorer Sa Nouveaux Taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2726272B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2170661A1 (en) * 1995-03-22 1996-09-23 John K. Thottathil Novel methods for the preparation of taxanes using oaxzolidine intermediates
FR2732342B1 (fr) * 1995-04-03 1997-04-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2732968B1 (fr) * 1995-04-14 1997-05-16 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2742438B1 (fr) * 1995-12-14 1998-01-16 Rhone Poulenc Rorer Sa Dihydrate du (2r,3s)-3-tert-butoxycarbonylamino-2-hydroxy- 3-phenylpropionate de 4,10beta-diacetoxy-2alpha-benzoyloxy- 5beta,2o-epoxy-1-hydroxy-9-oxo-19-nor-cyclopropa(g)tax-11- ene-13alpha-yle, et son procede de preparation
FR2742357B1 (fr) * 1995-12-19 1998-01-09 Rhone Poulenc Rorer Sa Nanoparticules stabilisees et filtrables dans des conditions steriles
FR2742753B1 (fr) * 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5919815A (en) * 1996-05-22 1999-07-06 Neuromedica, Inc. Taxane compounds and compositions
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
ES2151277T3 (es) * 1996-05-22 2000-12-16 Protarga Inc Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere.
ATE302599T1 (de) 1996-05-24 2005-09-15 Angiotech Pharm Inc Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege
FR2750989B1 (fr) * 1996-07-09 1998-09-25 Rhone Poulenc Rorer Sa Procede de monoacylation d'hydroxy taxanes
US5773464A (en) * 1996-09-30 1998-06-30 Bristol-Myers Squibb Company C-10 epoxy taxanes
WO1998017656A1 (en) 1996-10-24 1998-04-30 Institute Armand-Frappier A family of canadensol taxanes, the semi-synthetic preparation and therapeutic use thereof
US20030157187A1 (en) * 1996-12-02 2003-08-21 Angiotech Pharmaceuticals, Inc. Compositions and methods for treating or preventing inflammatory diseases
US6515016B2 (en) 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US6495579B1 (en) 1996-12-02 2002-12-17 Angiotech Pharmaceuticals, Inc. Method for treating multiple sclerosis
WO1998049321A2 (en) * 1997-04-28 1998-11-05 Rhone-Poulenc Rorer S.A. Adenovirus-mediated intratumoral delivery of an angiogenesis antagonist for the treatment of tumors
US7288665B1 (en) 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ATE234800T1 (de) 1997-08-21 2003-04-15 Univ Florida State Verfahren zur synthese von taxanen
US6831057B2 (en) * 1997-10-28 2004-12-14 The University Of North Carolina At Chapel Hill Use of NF-κB inhibition in combination therapy for cancer
US6150537A (en) * 1997-12-12 2000-11-21 Emory University Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents
CA2317728A1 (en) * 1998-01-14 1999-07-22 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
US6391911B1 (en) * 1999-02-26 2002-05-21 Robert E. Bases Coadministration of lucanthone and radiation for treatment of cancer
US7235583B1 (en) 1999-03-09 2007-06-26 Luitpold Pharmaceuticals, Inc., Fatty acid-anticancer conjugates and uses thereof
CA2365776A1 (en) * 1999-05-03 2000-11-09 Alain Renard Method for treating abnormal cell proliferation in the brain
FR2794771B1 (fr) 1999-06-11 2001-08-10 Aventis Pharma Sa Adenovirus recombinants codant pour le transporteur specifique de l'iode (nis)
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer
DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
MXPA03002494A (es) * 2000-09-22 2004-05-24 Bristol Myers Squibb Co Metodo para reducir toxicidad de quimio terapias combinadas.
DE60327651D1 (de) * 2002-10-09 2009-06-25 Chatham Biotec Ltd Thio-analoga von paclitaxel und deren vorprodukte
US7787855B2 (en) * 2003-03-31 2010-08-31 Motorola, Inc. Establishing emergency sessions in packet data networks for wireless devices having invalid subscriber identities
US6956124B2 (en) 2003-04-14 2005-10-18 Aventis Pharma S.A. Process for the preparation of 4,10β-diacetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene
US7202370B2 (en) * 2003-10-27 2007-04-10 Conor Medsystems, Inc. Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III
EP1960038B8 (en) * 2005-11-18 2021-04-07 Respicardia, Inc. System to modulate phrenic nerve to prevent sleep apnea
JP2009533330A (ja) * 2006-03-21 2009-09-17 ドクター レディズ ラボラトリーズ リミテッド ドセタキセルの多形体およびプロセス
CN100588643C (zh) * 2006-11-02 2010-02-10 南京航空航天大学 一种含有二取代金刚烷基的维甲酸类化合物制备方法
US20090076127A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched larotaxel
CN101863861A (zh) * 2009-04-16 2010-10-20 山东靶点药物研究有限公司 一种简便高效地制备紫杉醇类似物Larotaxel的方法
PE20121429A1 (es) 2009-10-29 2012-11-06 Aventis Pharma Sa Nuevo uso antitumoral de cabazitaxel
WO2011139899A2 (en) 2010-05-03 2011-11-10 Teikoku Pharma Usa, Inc. Non-aqueous taxane pro-emulsion formulations and methods of making and using the same
LT2753355T (lt) 2011-09-08 2019-01-25 New York University Onkolitinis herpes simplex virusas ir jo terapinis panaudojimas
US9745631B2 (en) 2011-12-20 2017-08-29 Dana-Farber Cancer Institute, Inc. Methods for diagnosing and treating oncogenic kras-associated cancer
US10138479B2 (en) 2012-05-24 2018-11-27 Dana-Farber Cancer Institute, Inc. Targeting the glutamine to pyruvate pathway for treatment of oncogenic Kras-associated cancer
US20150285802A1 (en) 2012-07-18 2015-10-08 Dana-Farber Cancer Institute, Inc. Methods for treating, preventing and predicting risk of developing breast cancer
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
US10238723B2 (en) 2013-03-14 2019-03-26 Icahn School Of Medicine At Mount Sinai Autologous tumor lysate-loaded dendritic cell vaccine for treatment of liver cancer
WO2015050844A1 (en) 2013-10-01 2015-04-09 Dana-Farber Cancer Institute, Inc. Methods of treating cancer with atovaquone-related compounds
WO2015149006A2 (en) 2014-03-27 2015-10-01 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating ncoa4-mediated autophagic targeting of ferritin
MA39818A (fr) 2014-03-30 2017-02-08 Benevir Biopharm Inc Virus oncolytiques « armés » comprenant un inhibiteur de tap exogène et leurs utilisations thérapeutiques
WO2016205429A1 (en) 2015-06-15 2016-12-22 New York University Method of treatment using oncolytic viruses
CN112574134A (zh) * 2020-12-30 2021-03-30 重庆市碚圣医药科技股份有限公司 一种多西紫杉醇侧链的合成方法

Family Cites Families (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US487399A (en) * 1892-12-06 Timepiece repeating mechanism
US4534899A (en) 1981-07-20 1985-08-13 Lipid Specialties, Inc. Synthetic phospholipid compounds
US4507217A (en) 1983-03-07 1985-03-26 Lipid Specialties, Inc. Magnetic compositions and magnetic memory devices prepared therefrom
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
US4876399A (en) 1987-11-02 1989-10-24 Research Corporation Technologies, Inc. Taxols, their preparation and intermediates thereof
GB8806224D0 (en) 1988-03-16 1988-04-13 Johnson Matthey Plc Platinum chemotherapeutic product
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5175315A (en) 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
MY110249A (en) 1989-05-31 1998-03-31 Univ Florida State Method for preparation of taxol using beta lactam
US5411947A (en) 1989-06-28 1995-05-02 Vestar, Inc. Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
US5136060A (en) 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5015744A (en) 1989-11-14 1991-05-14 Florida State University Method for preparation of taxol using an oxazinone
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
AU2005692A (en) 1991-05-08 1992-12-21 United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Method for designing cancer treatment regimens and methods and pharmaceutical compositions for the treatment of cancer
US5645988A (en) 1991-05-08 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Methods of identifying drugs with selective effects against cancer cells
US5698582A (en) 1991-07-08 1997-12-16 Rhone-Poulenc Rorer S.A. Compositions containing taxane derivatives
US5274124A (en) 1991-09-23 1993-12-28 Florida State University Metal alkoxides
US5739362A (en) 1991-09-23 1998-04-14 Florida State University Taxanes having an alkoxy, alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing them
US5284865A (en) 1991-09-23 1994-02-08 Holton Robert A Cyclohexyl substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5721268A (en) 1991-09-23 1998-02-24 Florida State University C7 taxane derivatives and pharmaceutical compositions containing them
US5728850A (en) 1991-09-23 1998-03-17 Florida State University Taxanes having a butenyl substituted side-chain and pharmaceutical compositions containing them
US5250683A (en) 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5229526A (en) 1991-09-23 1993-07-20 Florida State University Metal alkoxides
US5243045A (en) 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5338872A (en) 1993-01-15 1994-08-16 Florida State University Process for the preparation of 10-desacetoxybaccatin III and 10-desacetoxytaxol and derivatives thereof
US5430160A (en) 1991-09-23 1995-07-04 Florida State University Preparation of substituted isoserine esters using β-lactams and metal or ammonium alkoxides
US5399726A (en) 1993-01-29 1995-03-21 Florida State University Process for the preparation of baccatin III analogs bearing new C2 and C4 functional groups
US5283253A (en) 1991-09-23 1994-02-01 Florida State University Furyl or thienyl carbonyl substituted taxanes and pharmaceutical compositions containing them
US5654447A (en) 1991-09-23 1997-08-05 Florida State University Process for the preparation of 10-desacetoxybaccatin III
US5728725A (en) 1991-09-23 1998-03-17 Florida State University C2 taxane derivaties and pharmaceutical compositions containing them
US5350866A (en) 1991-09-23 1994-09-27 Bristol-Myers Squibb Company 10-desacetoxytaxol derivatives
US5714513A (en) 1991-09-23 1998-02-03 Florida State University C10 taxane derivatives and pharmaceutical compositions
US5710287A (en) 1991-09-23 1998-01-20 Florida State University Taxanes having an amino substituted side-chain and pharmaceutical compositions containing them
US5489601A (en) 1991-09-23 1996-02-06 Florida State University Taxanes having a pyridyl substituted side-chain and pharmaceutical compositions containing them
US5262409A (en) 1991-10-11 1993-11-16 Fred Hutchinson Cancer Research Center Binary tumor therapy
US5294737A (en) 1992-02-27 1994-03-15 The Research Foundation State University Of New York Process for the production of chiral hydroxy-β-lactams and hydroxyamino acids derived therefrom
AU3922193A (en) 1992-03-23 1993-10-21 Georgetown University Liposome encapsulated taxol and a method of using the same
US5254703A (en) 1992-04-06 1993-10-19 Florida State University Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones
US5254580A (en) 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
US5294637A (en) 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5319112A (en) 1992-08-18 1994-06-07 Virgnia Tech Intellectual Properties, Inc. Method for the conversion of cephalomannine to taxol and for the preparation of N-acyl analogs of taxol
FR2696459B1 (fr) 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2697752B1 (fr) 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
FR2698871B1 (fr) 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5814658A (en) 1992-12-09 1998-09-29 Rhone-Poulenc Rorer S.A. Taxoids, their preparation and pharmaceutical compositions containing them
MX9307777A (es) 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.
CA2111527C (en) 1992-12-24 2000-07-18 Jerzy Golik Phosphonooxymethyl ethers of taxane derivatives
ZA94128B (en) 1993-02-01 1994-08-19 Univ New York State Res Found Process for the preparation of taxane derivatives and betalactam intermediates therefor
FR2703049B1 (fr) 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.
WO1994026254A1 (en) 1993-05-17 1994-11-24 The Liposome Company, Inc. Incorporation of taxol into liposomes and gels
WO1994026253A1 (en) 1993-05-19 1994-11-24 The Liposome Company, Inc. Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5405972A (en) 1993-07-20 1995-04-11 Florida State University Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
CA2129288C (en) 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives
FR2712288B1 (fr) * 1993-11-08 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6441026B1 (en) 1993-11-08 2002-08-27 Aventis Pharma S.A. Antitumor compositions containing taxane derivatives
US5415869A (en) 1993-11-12 1995-05-16 The Research Foundation Of State University Of New York Taxol formulation
FR2718963B1 (fr) 1994-04-25 1996-05-24 Rhone Poulenc Rorer Sa Nouvelle composition pharmaceutique à base de taxoïdes.
AU2814595A (en) 1994-06-28 1996-01-25 Pharmacia & Upjohn Company 7-ether-taxol analogs, antineoplastic use and pharmaceutical compositions containing them
FR2721928A1 (fr) 1994-07-04 1996-01-05 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US6201140B1 (en) 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives
FR2726272B1 (fr) 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US5635531A (en) 1996-07-08 1997-06-03 Bristol-Myers Squibb Company 3'-aminocarbonyloxy paclitaxels
US6156789A (en) 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
EP0982028A1 (en) 1998-08-20 2000-03-01 Aventis Pharma S.A. New use of taxoid derivatives

Also Published As

Publication number Publication date
NO310555B1 (no) 2001-07-23
RO112281B1 (ro) 1997-07-30
AU4187097A (en) 1998-01-08
CA2150944A1 (fr) 1994-06-23
HU227872B1 (en) 2012-05-29
SG67338A1 (en) 1999-09-21
US5550261A (en) 1996-08-27
JPH10291930A (ja) 1998-11-04
US5599942A (en) 1997-02-04
SK75295A3 (en) 1995-11-08
PL175111B1 (pl) 1998-11-30
FR2698871B1 (fr) 1995-02-24
BR9307613A (pt) 1999-05-25
TW408120B (en) 2000-10-11
EP0673372B1 (fr) 2003-06-25
JP2785248B2 (ja) 1998-08-13
NZ258592A (en) 1996-12-20
NO952264L (no) 1995-06-08
HUT73134A (en) 1996-06-28
FI952825A0 (fi) 1995-06-08
US5580998A (en) 1996-12-03
DE69333064T2 (de) 2004-08-19
PL309293A1 (en) 1995-10-02
AU704663B2 (en) 1999-04-29
ES2202319T3 (es) 2004-04-01
MX9307748A (es) 1994-06-30
AU5653194A (en) 1994-07-04
CZ289851B6 (cs) 2002-04-17
US5576450A (en) 1996-11-19
RU2139864C1 (ru) 1999-10-20
BG99713A (bg) 1996-02-28
ATE243688T1 (de) 2003-07-15
KR950704287A (ko) 1995-11-17
OA10166A (fr) 1996-12-18
US5580997A (en) 1996-12-03
CA2150944C (fr) 2004-02-24
KR100346328B1 (ko) 2002-11-30
SK282139B6 (sk) 2001-11-06
WO1994013654A1 (fr) 1994-06-23
EP0673372A1 (fr) 1995-09-27
CN1094720A (zh) 1994-11-09
US5587493A (en) 1996-12-24
CN1055467C (zh) 2000-08-16
PT673372E (pt) 2003-11-28
PL175539B1 (pl) 1999-01-29
BG61726B1 (bg) 1998-04-30
US5571917A (en) 1996-11-05
DE69333064D1 (de) 2003-07-31
DK0673372T3 (da) 2003-10-13
FI952825A (fi) 1995-06-08
UA51612C2 (uk) 2002-12-16
CZ145595A3 (en) 1995-10-18
FR2698871A1 (fr) 1994-06-10
US5532388A (en) 1996-07-02
FI110941B (fi) 2003-04-30
PL174830B1 (pl) 1998-09-30
JPH08504425A (ja) 1996-05-14
US7074821B1 (en) 2006-07-11
HU9501662D0 (en) 1995-08-28
AU685415B2 (en) 1998-01-22

Similar Documents

Publication Publication Date Title
NO952264D0 (no) Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende taxoidene
NO953452D0 (no) Nye taxoider, deres fremstilling og farmasöytiske preparater inneholdende forbindelsene
EA199800588A1 (ru) Новые таксоиды, их получение и содержащие их фармацевтические композиции
RU95112464A (ru) Способ получения производных таксана
MX9707427A (es) Nuevos taxoides, su preparacion y las composiciones farmaceuticas que los contienen.
DK0630428T3 (da) Fremgangsmåde til fremstilling af taxanderivater
NO944141L (no) Nye taxanderivater, deres fremstilling og medikamenter inneholdende derivatene

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees