NO942549D0 - Humanproteaseinhibitorvariant av Kunitz-type - Google Patents

Humanproteaseinhibitorvariant av Kunitz-type

Info

Publication number
NO942549D0
NO942549D0 NO942549A NO942549A NO942549D0 NO 942549 D0 NO942549 D0 NO 942549D0 NO 942549 A NO942549 A NO 942549A NO 942549 A NO942549 A NO 942549A NO 942549 D0 NO942549 D0 NO 942549D0
Authority
NO
Norway
Prior art keywords
protease inhibitor
type human
human protease
kunitz type
inhibitor variant
Prior art date
Application number
NO942549A
Other languages
English (en)
Other versions
NO942549L (no
Inventor
Fanny Norris
Kjeld Norris
Soeren Erik Bjoern
Lars Christian Petersen
Ole Hvilsted Olsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO942549D0 publication Critical patent/NO942549D0/no
Publication of NO942549L publication Critical patent/NO942549L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114—Kunitz type inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO942549A 1992-01-07 1994-07-06 Humanproteaseinhibitorvariant av Kunitz-type NO942549L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK9200002 1992-01-07
DK9200340 1992-11-16
PCT/DK1993/000005 WO1993014122A1 (en) 1992-01-07 1993-01-07 A human kunitz-type protease inhibitor variant

Publications (2)

Publication Number Publication Date
NO942549D0 true NO942549D0 (no) 1994-07-06
NO942549L NO942549L (no) 1994-09-07

Family

ID=26068350

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942549A NO942549L (no) 1992-01-07 1994-07-06 Humanproteaseinhibitorvariant av Kunitz-type

Country Status (13)

Country Link
EP (1) EP0621872A1 (no)
JP (1) JPH07504891A (no)
AU (1) AU675926B2 (no)
CA (1) CA2127246A1 (no)
CZ (1) CZ164494A3 (no)
FI (1) FI943234A (no)
HU (1) HUT70293A (no)
IL (1) IL104324A0 (no)
NO (1) NO942549L (no)
NZ (1) NZ246570A (no)
RU (1) RU94036773A (no)
WO (1) WO1993014122A1 (no)
ZA (1) ZA9396B (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455338A (en) * 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
ATE275583T1 (de) * 1994-01-11 2004-09-15 Dyax Corp KALLIKREINHEMMENDE ßKUNITZ-DOMÄNEß-PROTEINE UND DERIVATEN DAVON
US6057287A (en) * 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
ES2229236T3 (es) * 1994-01-11 2005-04-16 Dyax Corporation Inhibidores de la plasmina humana derivados de los dominios de kunitz.
US5795954A (en) * 1994-03-04 1998-08-18 Genentech, Inc. Factor VIIa inhibitors from Kunitz domain proteins
US5589359A (en) * 1994-08-05 1996-12-31 Chiron Corporation Chimeric proteins
CA2196296C (en) * 1994-08-05 2004-04-06 Michael A. Innis Production of tissue factor pathway inhibitor
US5786328A (en) * 1995-06-05 1998-07-28 Genentech, Inc. Use of kunitz type plasma kallikrein inhibitors
US5780265A (en) * 1995-06-05 1998-07-14 Genentech, Inc. Kunitz type plasma kallikrein inhibitors
US6242414B1 (en) 1995-06-07 2001-06-05 Chiron Corporation Regulation of cytokine synthesis and release
JPH11507060A (ja) * 1995-06-07 1999-06-22 カイロン コーポレイション サイトカイン合成および放出の調節
US6521410B1 (en) * 1998-08-25 2003-02-18 Knut Kleesiek Mutant of tissue factor pathway inhibitor, DNA sequence and use for detecting thrombotic disorders
CN1325889A (zh) * 2000-05-26 2001-12-12 上海博德基因开发有限公司 一种新的多肽——人Kazal型抑制因子11和编码这种多肽的多核苷酸
ATE477020T1 (de) 2002-06-07 2010-08-15 Dyax Corp Prevention und verringerung von ischemia
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
PT2386310T (pt) * 2002-08-28 2019-02-05 Dyax Corp Métodos para preservar órgãos e tecidos
US6989369B2 (en) 2003-02-07 2006-01-24 Dyax Corp. Kunitz domain peptides
CA2536873C (en) 2003-08-29 2019-09-10 Dyax Corp. Poly-pegylated protease inhibitors
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
DK2379096T3 (da) 2008-12-19 2019-11-25 Baxalta GmbH TFPI-inhibitorer og fremgangsmåder til anvendelse
US8450275B2 (en) 2010-03-19 2013-05-28 Baxter International Inc. TFPI inhibitors and methods of use
AU2010203712A1 (en) 2009-01-06 2010-07-15 Dyax Corp. Treatment of mucositis with kallikrein inhibitors
JP6037841B2 (ja) 2010-01-06 2016-12-07 ダイアックス コーポレーション 血漿カリクレイン結合タンパク質
AU2012204202A1 (en) 2011-01-06 2013-07-11 Dyax Corp. Plasma kallikrein binding proteins
HUE046572T2 (hu) 2012-03-21 2020-03-30 Baxalta GmbH TFPI inhibitorok és alkalmazási eljárások
CN108602893A (zh) 2015-12-11 2018-09-28 戴埃克斯有限公司 血浆激肽释放酶抑制剂及其治疗遗传性血管性水肿发作的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106833A (en) * 1987-07-23 1992-04-21 Washington University Coagulation inhibitors
DK408089D0 (da) * 1989-08-18 1989-08-18 Novo Nordisk As Proteiner

Also Published As

Publication number Publication date
EP0621872A1 (en) 1994-11-02
NZ246570A (en) 1996-09-25
ZA9396B (en) 1993-08-10
AU675926B2 (en) 1997-02-27
IL104324A0 (en) 1993-05-13
RU94036773A (ru) 1996-09-27
CA2127246A1 (en) 1993-07-22
HU9401990D0 (en) 1994-09-28
NO942549L (no) 1994-09-07
HUT70293A (en) 1995-09-28
FI943234A0 (fi) 1994-07-06
JPH07504891A (ja) 1995-06-01
WO1993014122A1 (en) 1993-07-22
AU3346093A (en) 1993-08-03
FI943234A (fi) 1994-07-06
CZ164494A3 (en) 1994-12-15

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