NO942549D0 - Kunitz type human protease inhibitor variant - Google Patents

Kunitz type human protease inhibitor variant

Info

Publication number
NO942549D0
NO942549D0 NO942549A NO942549A NO942549D0 NO 942549 D0 NO942549 D0 NO 942549D0 NO 942549 A NO942549 A NO 942549A NO 942549 A NO942549 A NO 942549A NO 942549 D0 NO942549 D0 NO 942549D0
Authority
NO
Norway
Prior art keywords
protease inhibitor
type human
human protease
kunitz type
inhibitor variant
Prior art date
Application number
NO942549A
Other languages
Norwegian (no)
Other versions
NO942549L (en
Inventor
Fanny Norris
Kjeld Norris
Soeren Erik Bjoern
Lars Christian Petersen
Ole Hvilsted Olsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO942549D0 publication Critical patent/NO942549D0/en
Publication of NO942549L publication Critical patent/NO942549L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8114Kunitz type inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO942549A 1992-01-07 1994-07-06 Kunitz type human protease inhibitor variant NO942549L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK9200002 1992-01-07
DK9200340 1992-11-16
PCT/DK1993/000005 WO1993014122A1 (en) 1992-01-07 1993-01-07 A human kunitz-type protease inhibitor variant

Publications (2)

Publication Number Publication Date
NO942549D0 true NO942549D0 (en) 1994-07-06
NO942549L NO942549L (en) 1994-09-07

Family

ID=26068350

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942549A NO942549L (en) 1992-01-07 1994-07-06 Kunitz type human protease inhibitor variant

Country Status (13)

Country Link
EP (1) EP0621872A1 (en)
JP (1) JPH07504891A (en)
AU (1) AU675926B2 (en)
CA (1) CA2127246A1 (en)
CZ (1) CZ164494A3 (en)
FI (1) FI943234A0 (en)
HU (1) HUT70293A (en)
IL (1) IL104324A0 (en)
NO (1) NO942549L (en)
NZ (1) NZ246570A (en)
RU (1) RU94036773A (en)
WO (1) WO1993014122A1 (en)
ZA (1) ZA9396B (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455338A (en) * 1993-11-05 1995-10-03 Zymogenetics, Inc. DNA encoding novel human kunitz-type inhibitors and methods relating thereto
US6057287A (en) * 1994-01-11 2000-05-02 Dyax Corp. Kallikrein-binding "Kunitz domain" proteins and analogues thereof
EP1489097B1 (en) 1994-01-11 2011-10-19 Dyax Corporation Inhibitors of human plasmin derived from kunitz domains and nucleic acids encoding the same
DE69533472T2 (en) * 1994-01-11 2006-01-12 Dyax Corp., Cambridge KALLIKER INHIBITING "KUNITZ DOMAIN" PROTEINS AND DERIVATIVES THEREOF
US5795954A (en) * 1994-03-04 1998-08-18 Genentech, Inc. Factor VIIa inhibitors from Kunitz domain proteins
US5589359A (en) * 1994-08-05 1996-12-31 Chiron Corporation Chimeric proteins
ATE226249T1 (en) * 1994-08-05 2002-11-15 Chiron Corp PRODUCTION OF THE INHIBITOR FOR THE COMPLEX FORMATION OF THE TISSUE FACTOR
US5780265A (en) * 1995-06-05 1998-07-14 Genentech, Inc. Kunitz type plasma kallikrein inhibitors
US5786328A (en) * 1995-06-05 1998-07-28 Genentech, Inc. Use of kunitz type plasma kallikrein inhibitors
US6242414B1 (en) 1995-06-07 2001-06-05 Chiron Corporation Regulation of cytokine synthesis and release
JPH11507060A (en) * 1995-06-07 1999-06-22 カイロン コーポレイション Regulation of cytokine synthesis and release
WO2000011034A1 (en) * 1998-08-25 2000-03-02 Knut Kleesiek A mutant of tissue factor pathway inhibitor, dna sequence and use for detecting thrombotic disorders
CN1325889A (en) * 2000-05-26 2001-12-12 上海博德基因开发有限公司 Polypeptide-human kazal-type inhibitor 11 and polynucleotide for coding it
US7153829B2 (en) 2002-06-07 2006-12-26 Dyax Corp. Kallikrein-inhibitor therapies
ES2528254T3 (en) 2002-06-07 2015-02-05 Dyax Corp. Modified Kunitz domain polypeptides and their use to reduce ischemia or the onset of a systemic inflammatory response associated with a surgical procedure
ES2395014T3 (en) 2002-08-28 2013-02-07 Dyax Corp. Methods to preserve organs and tissues
US6989369B2 (en) 2003-02-07 2006-01-24 Dyax Corp. Kunitz domain peptides
DK1663281T3 (en) 2003-08-29 2014-03-17 Dyax Corp POLY-PEGYLED PROTEASE INHIBITORS
US7235530B2 (en) 2004-09-27 2007-06-26 Dyax Corporation Kallikrein inhibitors and anti-thrombolytic agents and uses thereof
US7276480B1 (en) 2005-12-30 2007-10-02 Dyax Corp. Prevention and reduction of blood loss
CN104984319A (en) 2008-12-19 2015-10-21 巴克斯特国际公司 Tfpi inhibitors and methods of use
EP2385843A4 (en) 2009-01-06 2013-02-27 Dyax Corp Treatment of mucositis with kallikrein inhibitors
PT3459564T (en) 2010-01-06 2022-01-31 Takeda Pharmaceuticals Co Plasma kallikrein binding proteins
ES2621809T3 (en) 2010-03-19 2017-07-05 Baxalta GmbH TFPI inhibitors and use procedures
KR102107695B1 (en) 2011-01-06 2020-05-07 다이액스 코포레이션 Plasma kallikrein binding proteins
DK2827883T3 (en) 2012-03-21 2019-07-29 Baxalta GmbH TFPI INHIBITORS AND METHODS OF USE
US11286307B2 (en) 2015-12-11 2022-03-29 Takeda Pharmaceutical Company Limited Plasma kallikrein inhibitors and uses thereof for treating hereditary angioedema attack

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106833A (en) * 1987-07-23 1992-04-21 Washington University Coagulation inhibitors
DK408089D0 (en) * 1989-08-18 1989-08-18 Novo Nordisk As PROTEINS

Also Published As

Publication number Publication date
ZA9396B (en) 1993-08-10
HUT70293A (en) 1995-09-28
JPH07504891A (en) 1995-06-01
WO1993014122A1 (en) 1993-07-22
FI943234A (en) 1994-07-06
HU9401990D0 (en) 1994-09-28
AU3346093A (en) 1993-08-03
IL104324A0 (en) 1993-05-13
AU675926B2 (en) 1997-02-27
RU94036773A (en) 1996-09-27
CA2127246A1 (en) 1993-07-22
EP0621872A1 (en) 1994-11-02
NZ246570A (en) 1996-09-25
NO942549L (en) 1994-09-07
FI943234A0 (en) 1994-07-06
CZ164494A3 (en) 1994-12-15

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