NO942376L - Terapeutiske midler - Google Patents
Terapeutiske midlerInfo
- Publication number
- NO942376L NO942376L NO942376A NO942376A NO942376L NO 942376 L NO942376 L NO 942376L NO 942376 A NO942376 A NO 942376A NO 942376 A NO942376 A NO 942376A NO 942376 L NO942376 L NO 942376L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- represents hydrogen
- halogen
- halo
- carboxy
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 229910052739 hydrogen Inorganic materials 0.000 abstract 9
- 239000001257 hydrogen Substances 0.000 abstract 9
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 8
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical group 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002723 alicyclic group Chemical group 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000005080 alkoxycarbonylalkenyl group Chemical group 0.000 abstract 1
- 125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000005019 carboxyalkenyl group Chemical group 0.000 abstract 1
- 125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Rheumatology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919127252A GB9127252D0 (en) | 1991-12-23 | 1991-12-23 | Therapeutic agents |
| PCT/EP1992/002901 WO1993013097A1 (en) | 1991-12-23 | 1992-12-12 | Anti-rheumatic naphthyridine derivatives |
| CN93109454A CN1096784A (zh) | 1991-12-23 | 1993-06-22 | 含取代4(5)-氨基-1,8-二氨杂萘的治疗剂 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO942376D0 NO942376D0 (enExample) | 1994-06-22 |
| NO942376L true NO942376L (no) | 1994-06-22 |
Family
ID=36822317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO942376A NO942376L (no) | 1991-12-23 | 1994-06-22 | Terapeutiske midler |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5464781A (enExample) |
| EP (1) | EP0618916B1 (enExample) |
| JP (1) | JP2527917B2 (enExample) |
| CN (1) | CN1096784A (enExample) |
| AT (1) | ATE171452T1 (enExample) |
| AU (1) | AU656832B2 (enExample) |
| BG (1) | BG98813A (enExample) |
| CA (1) | CA2125858A1 (enExample) |
| CZ (1) | CZ153594A3 (enExample) |
| DE (1) | DE69227125T2 (enExample) |
| FI (1) | FI943019A7 (enExample) |
| GB (1) | GB9127252D0 (enExample) |
| HR (1) | HRP921455A2 (enExample) |
| HU (1) | HUT66971A (enExample) |
| IL (1) | IL104169A0 (enExample) |
| IN (1) | IN174405B (enExample) |
| MX (1) | MX9207494A (enExample) |
| NO (1) | NO942376L (enExample) |
| NZ (1) | NZ246156A (enExample) |
| SI (1) | SI9200408A (enExample) |
| SK (1) | SK75094A3 (enExample) |
| WO (1) | WO1993013097A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9312891D0 (en) * | 1993-06-22 | 1993-08-04 | Boots Co Plc | Therapeutic agents |
| GB9318931D0 (en) * | 1993-09-14 | 1993-10-27 | Boots Co Plc | Therapeutic agents |
| GB9420168D0 (en) * | 1994-10-06 | 1994-11-23 | Boots Co Plc | Therapeutic agents |
| AR004010A1 (es) | 1995-10-11 | 1998-09-30 | Glaxo Group Ltd | Compuestos heterociclicos |
| WO1998013350A1 (en) | 1996-09-25 | 1998-04-02 | Zeneca Limited | Qinoline derivatives inhibiting the effect of growth factors such as vegf |
| GB9800569D0 (en) | 1998-01-12 | 1998-03-11 | Glaxo Group Ltd | Heterocyclic compounds |
| US6166069A (en) * | 1998-05-12 | 2000-12-26 | American Home Products Corporation | Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| JP2003504363A (ja) | 1999-07-09 | 2003-02-04 | グラクソ グループ リミテッド | プロテインチロシンキナーゼ阻害剤としてのアニリノキナゾリン類 |
| US6933299B1 (en) | 1999-07-09 | 2005-08-23 | Smithkline Beecham Corporation | Anilinoquinazolines as protein tyrosine kinase inhibitors |
| AU779695B2 (en) | 2000-04-07 | 2005-02-10 | Astrazeneca Ab | Quinazoline compounds |
| US6534656B2 (en) * | 2001-05-31 | 2003-03-18 | North Carolina State University | Short synthesis of pyridine-based pharmaceutical intermediates |
| JP2003329989A (ja) * | 2002-03-06 | 2003-11-19 | Nippon Telegr & Teleph Corp <Ntt> | 光送信装置 |
| GB0230018D0 (en) | 2002-12-23 | 2003-01-29 | Syngenta Ltd | Fungicides |
| CN1984660B (zh) | 2003-07-03 | 2010-12-15 | 美瑞德生物工程公司 | 作为天冬氨酸特异性半胱氨酸蛋白酶活化剂和细胞程序死亡诱导剂的4-芳基氨基-喹唑啉 |
| US8309562B2 (en) * | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| KR100807920B1 (ko) | 2003-12-23 | 2008-02-27 | 화이자 인코포레이티드 | 신규한 퀴놀린 유도체 |
| EP1833482A4 (en) | 2005-01-03 | 2011-02-16 | Myriad Genetics Inc | COMPOUNDS AND ITS THERAPEUTIC USE |
| US8258145B2 (en) * | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| EP2345652A1 (en) | 2005-12-21 | 2011-07-20 | Abbott Laboratories | Antiviral compounds |
| RU2467007C2 (ru) | 2005-12-21 | 2012-11-20 | Эбботт Лэборетриз | Производные [1,8]нафтиридина, полезные в качестве ингибиторов репликации вируса hcv |
| ES2395386T3 (es) * | 2005-12-21 | 2013-02-12 | Abbott Laboratories | Compuestos antivirales |
| RU2441869C2 (ru) * | 2005-12-21 | 2012-02-10 | Эбботт Лэборетриз | Противовирусные соединения |
| TWI392676B (zh) * | 2005-12-21 | 2013-04-11 | Abbott Lab | 抗病毒化合物、其製備方法及用途 |
| CA2672737A1 (en) | 2006-12-20 | 2008-11-06 | Abbott Laboratories | Anti-viral compounds |
| KR20110025856A (ko) * | 2008-07-03 | 2011-03-11 | 메르크 파텐트 게엠베하 | 오로라 키나아제 억제제로서 나프티리디니논 |
| US8415333B2 (en) | 2009-02-24 | 2013-04-09 | Respiratorious Ab | Bronchodilating diazaheteroaryls |
| WO2011063398A1 (en) * | 2009-11-23 | 2011-05-26 | Cylene Pharamaceuticals, Inc. | Polymorphs and salts of a kinase inhibitor |
| NZ603332A (en) | 2010-04-02 | 2014-11-28 | Senomyx Inc | Sweet flavor modifier |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4466965A (en) * | 1982-07-26 | 1984-08-21 | American Hospital Supply Corporation | Phthalazine compounds, compositions and use |
| NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
| EP0222839A4 (en) * | 1985-05-17 | 1988-11-09 | Univ Australian | ANTI-MALARIA COMPOUNDS. |
| JPS6368568A (ja) * | 1986-09-10 | 1988-03-28 | Otsuka Pharmaceut Factory Inc | ｐ−アミノフエノ−ル誘導体 |
| DE3644825A1 (de) * | 1986-12-31 | 1988-07-14 | Basf Ag | Substituierte 1,8-naphthyridin-derivate und diese enthaltende fungizide |
| EP0302303A3 (en) * | 1987-07-22 | 1989-05-24 | Schering Corporation | Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation |
| GB8804443D0 (en) * | 1988-02-25 | 1988-03-23 | Smithkline Beckman Intercredit | Compounds |
| US4978661A (en) * | 1988-09-29 | 1990-12-18 | Innocenzo Caruso | Use of 6-halo-4-quinolone compounds and pharmaceutical compositions thereof for the preparation of a medicament for the therapeutical application in rheumatoid arthritis |
| GR900100380A (el) * | 1989-05-20 | 1991-10-10 | Fisons Plc | Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης. |
| AU634561B2 (en) * | 1989-07-27 | 1993-02-25 | Eli Lilly And Company | Naphthyridine derivatives |
| JP2988739B2 (ja) * | 1990-04-16 | 1999-12-13 | 協和醗酵工業株式会社 | １，８−ナフチリジン−２−オン誘導体 |
| JP3157077B2 (ja) * | 1994-02-16 | 2001-04-16 | 内山工業株式会社 | ベアリングシール |
-
1991
- 1991-12-23 GB GB919127252A patent/GB9127252D0/en active Pending
-
1992
- 1992-10-12 US US08/244,369 patent/US5464781A/en not_active Expired - Lifetime
- 1992-12-12 EP EP93900052A patent/EP0618916B1/en not_active Expired - Lifetime
- 1992-12-12 AU AU31587/93A patent/AU656832B2/en not_active Ceased
- 1992-12-12 CZ CZ941535A patent/CZ153594A3/cs unknown
- 1992-12-12 AT AT93900052T patent/ATE171452T1/de not_active IP Right Cessation
- 1992-12-12 WO PCT/EP1992/002901 patent/WO1993013097A1/en not_active Ceased
- 1992-12-12 DE DE69227125T patent/DE69227125T2/de not_active Expired - Fee Related
- 1992-12-12 HU HU9401877A patent/HUT66971A/hu unknown
- 1992-12-12 JP JP5511397A patent/JP2527917B2/ja not_active Expired - Fee Related
- 1992-12-12 SK SK750-94A patent/SK75094A3/sk unknown
- 1992-12-12 NZ NZ246156A patent/NZ246156A/en unknown
- 1992-12-12 CA CA002125858A patent/CA2125858A1/en not_active Abandoned
- 1992-12-17 IN IN758MA1992 patent/IN174405B/en unknown
- 1992-12-18 IL IL104169A patent/IL104169A0/xx unknown
- 1992-12-22 MX MX9207494A patent/MX9207494A/es unknown
- 1992-12-22 HR HR921455A patent/HRP921455A2/hr not_active Application Discontinuation
- 1992-12-22 SI SI19929200408A patent/SI9200408A/sl unknown
-
1993
- 1993-06-22 CN CN93109454A patent/CN1096784A/zh active Pending
-
1994
- 1994-05-31 BG BG98813A patent/BG98813A/bg unknown
- 1994-06-22 FI FI943019A patent/FI943019A7/fi not_active Application Discontinuation
- 1994-06-22 NO NO942376A patent/NO942376L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU3158793A (en) | 1993-07-28 |
| HUT66971A (en) | 1995-01-30 |
| JPH07502280A (ja) | 1995-03-09 |
| NZ246156A (en) | 1996-01-26 |
| DE69227125T2 (de) | 1999-02-18 |
| FI943019A0 (fi) | 1994-06-22 |
| HRP921455A2 (en) | 1994-12-31 |
| SK75094A3 (en) | 1995-04-12 |
| JP2527917B2 (ja) | 1996-08-28 |
| NO942376D0 (enExample) | 1994-06-22 |
| FI943019A7 (fi) | 1994-06-22 |
| MX9207494A (es) | 1993-07-01 |
| ATE171452T1 (de) | 1998-10-15 |
| AU656832B2 (en) | 1995-02-16 |
| BG98813A (bg) | 1995-05-31 |
| HU9401877D0 (en) | 1994-09-28 |
| EP0618916B1 (en) | 1998-09-23 |
| CN1096784A (zh) | 1994-12-28 |
| IN174405B (enExample) | 1994-11-26 |
| WO1993013097A1 (en) | 1993-07-08 |
| EP0618916A1 (en) | 1994-10-12 |
| DE69227125D1 (de) | 1998-10-29 |
| GB9127252D0 (en) | 1992-02-19 |
| SI9200408A (en) | 1993-09-30 |
| CZ153594A3 (en) | 1995-02-15 |
| US5464781A (en) | 1995-11-07 |
| CA2125858A1 (en) | 1993-07-08 |
| IL104169A0 (en) | 1993-05-13 |
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