NO941977L - Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav - Google Patents

Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav

Info

Publication number
NO941977L
NO941977L NO941977A NO941977A NO941977L NO 941977 L NO941977 L NO 941977L NO 941977 A NO941977 A NO 941977A NO 941977 A NO941977 A NO 941977A NO 941977 L NO941977 L NO 941977L
Authority
NO
Norway
Prior art keywords
agent
processes
preparation
medical use
indole derivatives
Prior art date
Application number
NO941977A
Other languages
English (en)
Norwegian (no)
Other versions
NO941977D0 (no
Inventor
Hiroshi Nagase
Akira Mizusuna
Koji Kawai
Izumi Nakatani
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of NO941977D0 publication Critical patent/NO941977D0/no
Publication of NO941977L publication Critical patent/NO941977L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
NO941977A 1992-09-29 1994-05-27 Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav NO941977L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25984192 1992-09-29
PCT/JP1993/001388 WO1994007896A1 (fr) 1992-09-29 1993-09-29 Derive indole, procede pour sa fabrication, et son usage medicinal

Publications (2)

Publication Number Publication Date
NO941977D0 NO941977D0 (no) 1994-05-27
NO941977L true NO941977L (no) 1994-07-29

Family

ID=17339733

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941977A NO941977L (no) 1992-09-29 1994-05-27 Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav

Country Status (14)

Country Link
US (2) US6087369A (cs)
EP (1) EP0614898B1 (cs)
JP (1) JP3605825B2 (cs)
KR (1) KR100301093B1 (cs)
CN (1) CN1043766C (cs)
AT (1) ATE239732T1 (cs)
AU (1) AU672033B2 (cs)
CA (1) CA2124455C (cs)
DE (1) DE69332945T2 (cs)
ES (1) ES2199220T3 (cs)
FI (1) FI942499A7 (cs)
NO (1) NO941977L (cs)
TW (1) TW271440B (cs)
WO (1) WO1994007896A1 (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994007896A1 (fr) 1992-09-29 1994-04-14 Toray Industries, Inc. Derive indole, procede pour sa fabrication, et son usage medicinal
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
SE9401727D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds I
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II
US5578725A (en) * 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
CA2205664C (en) * 1995-09-26 2008-05-20 Toray Industries, Inc. Indole derivatives and medicinal use thereof
US5994327A (en) * 1995-11-17 1999-11-30 Astra Ab Process for the preparation of morphinans
BR9707136A (pt) * 1996-01-10 1999-08-31 Smithkline Beecham Spa Derivados morfinóides condesados em heterociclo (ii)
CN1117754C (zh) * 1997-01-16 2003-08-13 东丽株式会社 吲哚并吗啡喃衍生物及其组合物
TW519543B (en) 1997-03-31 2003-02-01 Toray Industries Quinolinomorphinan derivative and pharmaceutical composition for curing-preventing cerebral disorder
US5986141A (en) * 1998-09-29 1999-11-16 Eastman Chemical Company Process for the production of cyclopropanemethylamine
DE60039444D1 (de) * 1999-08-24 2008-08-21 Toray Industries Heilmittel für neuropathischen schmerz und versuchstier-modelle des neuropathischen schmerzes
US8205237B2 (en) 2000-09-14 2012-06-19 Cox Ingemar J Identifying works, using a sub-linear time search, such as an approximate nearest neighbor search, for initiating a work-based action, such as an action on the internet
US7232829B2 (en) 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
EP1392298B1 (en) 2001-05-04 2009-02-18 Amgen Inc. Fused heterocyclic compounds
AU2003205332A1 (en) * 2002-01-25 2003-09-02 Philip S. Portoghese Selective analgesic agents
KR20050103184A (ko) 2002-11-06 2005-10-27 암젠 인코포레이션 융합된 헤테로사이클릭 화합물들
EP1595541A1 (en) 2004-05-12 2005-11-16 Alcasynn Pharmaceuticals Gmbh Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin
ES2784690T3 (es) 2013-12-05 2020-09-29 Univ Bath Nuevos compuestos opioides y sus usos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631829A1 (de) * 1986-09-19 1988-07-28 Hoechst Ag Klonierung und verwendung des transaminase gens-tyrb
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
JPH04342529A (ja) * 1991-05-21 1992-11-30 Toray Ind Inc 抗アレルギー剤
US5354863A (en) * 1992-01-21 1994-10-11 G. D. Searle & Co. Opioid agonist compounds
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5352680A (en) * 1992-07-15 1994-10-04 Regents Of The University Of Minnesota Delta opioid receptor antagonists to block opioid agonist tolerance and dependence
WO1994007896A1 (fr) * 1992-09-29 1994-04-14 Toray Industries, Inc. Derive indole, procede pour sa fabrication, et son usage medicinal
US5457208A (en) * 1993-06-21 1995-10-10 Regents Of The University Of Minnesota Kappa opioid receptor antagonists
CA2205664C (en) * 1995-09-26 2008-05-20 Toray Industries, Inc. Indole derivatives and medicinal use thereof

Also Published As

Publication number Publication date
JP3605825B2 (ja) 2004-12-22
CN1092425A (zh) 1994-09-21
EP0614898B1 (en) 2003-05-07
EP0614898A4 (en) 1994-10-12
US6291470B1 (en) 2001-09-18
DE69332945T2 (de) 2004-05-19
NO941977D0 (no) 1994-05-27
US6087369A (en) 2000-07-11
ES2199220T3 (es) 2004-02-16
AU672033B2 (en) 1996-09-19
FI942499A0 (fi) 1994-05-27
CA2124455C (en) 2004-09-14
FI942499L (fi) 1994-07-27
AU4834193A (en) 1994-04-26
FI942499A7 (fi) 1994-07-27
ATE239732T1 (de) 2003-05-15
WO1994007896A1 (fr) 1994-04-14
EP0614898A1 (en) 1994-09-14
TW271440B (cs) 1996-03-01
CA2124455A1 (en) 1994-04-14
KR100301093B1 (ko) 2001-10-22
DE69332945D1 (de) 2003-06-12
CN1043766C (zh) 1999-06-23

Similar Documents

Publication Publication Date Title
NO941977L (no) Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav
NO882608D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive pyrazolopyrideirer.
HU9500240D0 (en) New prolin-amide derivatives and pharmaceutical compositions containing them as active component
NO900306L (no) Fremgangsmaate for fremstilling av nye pyrazolopyridin-forbindelser.
DK66789D0 (da) Bicycloheptencarboxylsyrederivater
CU22305A3 (es) Procedimiento para la preparacion de un derivado de aminoacidos
DK0393493T3 (da) Fluorerede galdesyrederivater, fremgangsmåder til fremstilling heraf og farmaceutiske midler, som indeholder dem
NO156690C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive indanderivater.
NO160297C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-oksoazetidinderivater
NO158017C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive imidazolderivater.
ES538847A0 (es) Un derivado de fenilserina
PT81246B (pt) Processo para a preparacao de pirazolo-piridino-amidas e dos seus derivados 7-n-oxidos e de composicoes farmaceuticas contendo estes compostos
NO20045132L (no) Benzo(c)kinolizinderivater, deres fremstilling og anvendelse som 5alfa- reduktaseinhibitorer
ES8604167A1 (es) Un procedimiento para la preparacion de un derivado de acido 2-anilino-1, 6-dihidro-6-oxo-5-pirimidincarboxilico
DE3668888D1 (de) Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung.
NO883263D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive benzimidazol-derivater.
NO894325D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive pyrrolidin-derivater.
DE69000806D1 (de) Indol-derivate.
NO164170C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 1-benzhydryl-4-cinnamyl-piperazinderivater.
GB2011887A (en) Antiallergic agent
DK400385A (da) Arphameninderivater, fremgangsmaade til deres fremstilling samt anvendelse heraf som laegemiddel
GB1164496A (en) 0-Oxaphenanthridine Derivatives and Method for the Preparation
ES509154A0 (es) Un procedimiento para la preparacion de nuevos derivados del acido &-glutamil-diaminopimelilo.