NO941977D0 - Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav - Google Patents

Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav

Info

Publication number
NO941977D0
NO941977D0 NO941977A NO941977A NO941977D0 NO 941977 D0 NO941977 D0 NO 941977D0 NO 941977 A NO941977 A NO 941977A NO 941977 A NO941977 A NO 941977A NO 941977 D0 NO941977 D0 NO 941977D0
Authority
NO
Norway
Prior art keywords
alkyl
processes
preparation
represents hydrogen
medical use
Prior art date
Application number
NO941977A
Other languages
English (en)
Other versions
NO941977L (no
Inventor
Hiroshi Nagase
Akira Mizusuna
Koji Kawai
Izumi Nakatani
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of NO941977D0 publication Critical patent/NO941977D0/no
Publication of NO941977L publication Critical patent/NO941977L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
NO941977A 1992-09-29 1994-05-27 Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav NO941977L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25984192 1992-09-29
PCT/JP1993/001388 WO1994007896A1 (en) 1992-09-29 1993-09-29 Indole derivative, process for producing the same, and medicinal use thereof

Publications (2)

Publication Number Publication Date
NO941977D0 true NO941977D0 (no) 1994-05-27
NO941977L NO941977L (no) 1994-07-29

Family

ID=17339733

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941977A NO941977L (no) 1992-09-29 1994-05-27 Indolderivater, fremgangsmåte for fremstilling av disse, og medisinsk anvendelse derav

Country Status (14)

Country Link
US (2) US6087369A (no)
EP (1) EP0614898B1 (no)
JP (1) JP3605825B2 (no)
KR (1) KR100301093B1 (no)
CN (1) CN1043766C (no)
AT (1) ATE239732T1 (no)
AU (1) AU672033B2 (no)
CA (1) CA2124455C (no)
DE (1) DE69332945T2 (no)
ES (1) ES2199220T3 (no)
FI (1) FI942499A (no)
NO (1) NO941977L (no)
TW (1) TW271440B (no)
WO (1) WO1994007896A1 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1043766C (zh) * 1992-09-29 1999-06-23 东丽株式会社 吲哚衍生物及其制法和它们在制备药物中的应用
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
SE9401727D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds I
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II
US5578725A (en) * 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
PT805157E (pt) * 1995-09-26 2003-10-31 Toray Industries Derivados do indole e sua utilizacao medicinal
US5994327A (en) * 1995-11-17 1999-11-30 Astra Ab Process for the preparation of morphinans
CA2242609A1 (en) * 1996-01-10 1997-07-17 Smithkline Beecham S.P.A. Heterocycle-condensed morphinoid derivatives (ii)
ATE263769T1 (de) * 1997-01-16 2004-04-15 Toray Industries Indolmorphinan-derivate und medikamente zur behandlung/mittel zur vorbeugung von cerebralen störungen
WO1998043977A1 (fr) * 1997-03-31 1998-10-08 Toray Industries, Inc. Derives de quinolinomorphinane et leur usage medical
US5986141A (en) * 1998-09-29 1999-11-16 Eastman Chemical Company Process for the production of cyclopropanemethylamine
EP1219624B1 (en) * 1999-08-24 2008-07-09 Toray Industries, Inc. Remedies for neuropathic pain and model animals of neuropathic pain
US8205237B2 (en) 2000-09-14 2012-06-19 Cox Ingemar J Identifying works, using a sub-linear time search, such as an approximate nearest neighbor search, for initiating a work-based action, such as an action on the internet
US7232829B2 (en) 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
EP1392298B1 (en) 2001-05-04 2009-02-18 Amgen Inc. Fused heterocyclic compounds
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
JP2005530685A (ja) * 2002-01-25 2005-10-13 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 選択的鎮痛剤
PL376659A1 (pl) 2002-11-06 2006-01-09 Tularik Inc. Skondensowane związki heterocykliczne
EP1595541A1 (en) * 2004-05-12 2005-11-16 Alcasynn Pharmaceuticals Gmbh Use of opioid receptor antagonist compounds for the prevention and/or treatment of diseases associated with the target calcineurin
ES2784690T3 (es) 2013-12-05 2020-09-29 Univ Bath Nuevos compuestos opioides y sus usos

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631829A1 (de) * 1986-09-19 1988-07-28 Hoechst Ag Klonierung und verwendung des transaminase gens-tyrb
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP2906654B2 (ja) * 1989-11-28 1999-06-21 東レ株式会社 免疫抑制剤及びその製造方法
JPH04342529A (ja) * 1991-05-21 1992-11-30 Toray Ind Inc 抗アレルギー剤
US5354863A (en) * 1992-01-21 1994-10-11 G. D. Searle & Co. Opioid agonist compounds
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5352680A (en) * 1992-07-15 1994-10-04 Regents Of The University Of Minnesota Delta opioid receptor antagonists to block opioid agonist tolerance and dependence
CN1043766C (zh) * 1992-09-29 1999-06-23 东丽株式会社 吲哚衍生物及其制法和它们在制备药物中的应用
US5457208A (en) * 1993-06-21 1995-10-10 Regents Of The University Of Minnesota Kappa opioid receptor antagonists
PT805157E (pt) * 1995-09-26 2003-10-31 Toray Industries Derivados do indole e sua utilizacao medicinal

Also Published As

Publication number Publication date
DE69332945D1 (de) 2003-06-12
CA2124455C (en) 2004-09-14
ES2199220T3 (es) 2004-02-16
US6291470B1 (en) 2001-09-18
JP3605825B2 (ja) 2004-12-22
ATE239732T1 (de) 2003-05-15
AU4834193A (en) 1994-04-26
CA2124455A1 (en) 1994-04-14
FI942499A (fi) 1994-07-27
KR100301093B1 (ko) 2001-10-22
EP0614898B1 (en) 2003-05-07
NO941977L (no) 1994-07-29
AU672033B2 (en) 1996-09-19
DE69332945T2 (de) 2004-05-19
CN1043766C (zh) 1999-06-23
EP0614898A1 (en) 1994-09-14
EP0614898A4 (en) 1994-10-12
US6087369A (en) 2000-07-11
FI942499A0 (fi) 1994-05-27
CN1092425A (zh) 1994-09-21
WO1994007896A1 (en) 1994-04-14
TW271440B (no) 1996-03-01

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