PT805157E - Derivados do indole e sua utilizacao medicinal - Google Patents

Derivados do indole e sua utilizacao medicinal

Info

Publication number
PT805157E
PT805157E PT96932007T PT96932007T PT805157E PT 805157 E PT805157 E PT 805157E PT 96932007 T PT96932007 T PT 96932007T PT 96932007 T PT96932007 T PT 96932007T PT 805157 E PT805157 E PT 805157E
Authority
PT
Portugal
Prior art keywords
indole derivatives
medicinal use
present
antitussives
analgesics
Prior art date
Application number
PT96932007T
Other languages
English (en)
Inventor
Hiroshi Nagase
Takashi Endo
Koji Kawai
Shinya Ueno
Masayuki Maeda
Satoshi Sakami
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of PT805157E publication Critical patent/PT805157E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT96932007T 1995-09-26 1996-09-26 Derivados do indole e sua utilizacao medicinal PT805157E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24747295 1995-09-26

Publications (1)

Publication Number Publication Date
PT805157E true PT805157E (pt) 2003-10-31

Family

ID=17163970

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96932007T PT805157E (pt) 1995-09-26 1996-09-26 Derivados do indole e sua utilizacao medicinal

Country Status (13)

Country Link
US (1) US5849731A (pt)
EP (1) EP0805157B1 (pt)
JP (1) JP3123080B2 (pt)
CN (1) CN1093862C (pt)
AT (1) ATE242247T1 (pt)
AU (1) AU712012B2 (pt)
CA (1) CA2205664C (pt)
DE (1) DE69628543T2 (pt)
ES (1) ES2197953T3 (pt)
NO (1) NO972377L (pt)
PT (1) PT805157E (pt)
TW (1) TW344742B (pt)
WO (1) WO1997011948A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2124455C (en) 1992-09-29 2004-09-14 Hiroshi Nagase Indole derivatives, process for producing the same and medicinal uses of the same
WO2001014383A1 (fr) * 1999-08-24 2001-03-01 Toray Industries, Inc. Remedes contre les douleurs neuropathiques et modeles animaux de douleurs neuropathiques
AU2408602A (en) 2000-11-22 2002-06-03 Toray Industries Indole derivatives and use thereof in medicines
CN1758912A (zh) * 2003-03-07 2006-04-12 东丽株式会社 药物·物质依赖治疗药
EP2277875A3 (en) * 2004-01-30 2011-04-20 Euro-Celtique S.A. Methods for making 4-tetrazolyl-4-phenylpiperidine compounds
JPWO2006064780A1 (ja) * 2004-12-14 2008-06-12 塩野義製薬株式会社 便秘治療剤
WO2008001859A1 (fr) * 2006-06-30 2008-01-03 School Juridical Person Kitasato Gakuen AGONISTE DES RÉCEPTEURS δ DES OPIOÏDES
JP5213157B2 (ja) * 2007-08-24 2013-06-19 学校法人北里研究所 6,14−エポキシモルヒナン誘導体およびその医薬用途
WO2015082932A1 (en) 2013-12-05 2015-06-11 The University Of Bath Novel opioid compounds and their uses
AU2019229892A1 (en) 2018-03-08 2020-09-03 University Of Kansas Treatment of demyelinating diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
US5354863A (en) * 1992-01-21 1994-10-11 G. D. Searle & Co. Opioid agonist compounds
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
CA2124455C (en) * 1992-09-29 2004-09-14 Hiroshi Nagase Indole derivatives, process for producing the same and medicinal uses of the same
DE69318710T2 (de) * 1992-12-22 1998-09-10 Toray Industries Antitussivum
US5457208A (en) * 1993-06-21 1995-10-10 Regents Of The University Of Minnesota Kappa opioid receptor antagonists
US5411965A (en) * 1993-08-23 1995-05-02 Arizona Board Of Regents Use of delta opioid receptor antagonists to treat cocaine abuse
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
SE9401727D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds I
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II

Also Published As

Publication number Publication date
EP0805157A1 (en) 1997-11-05
AU712012B2 (en) 1999-10-28
AU7096096A (en) 1997-04-17
DE69628543T2 (de) 2003-12-11
NO972377D0 (no) 1997-05-23
EP0805157A4 (en) 1999-01-07
CA2205664A1 (en) 1997-04-03
DE69628543D1 (de) 2003-07-10
ES2197953T3 (es) 2004-01-16
TW344742B (en) 1998-11-11
WO1997011948A1 (fr) 1997-04-03
CN1165517A (zh) 1997-11-19
ATE242247T1 (de) 2003-06-15
US5849731A (en) 1998-12-15
CA2205664C (en) 2008-05-20
CN1093862C (zh) 2002-11-06
JP3123080B2 (ja) 2001-01-09
EP0805157B1 (en) 2003-06-04
NO972377L (no) 1997-07-23

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