ATE242247T1 - Indolderivate und ihre medizinische verwendung - Google Patents

Indolderivate und ihre medizinische verwendung

Info

Publication number
ATE242247T1
ATE242247T1 AT96932007T AT96932007T ATE242247T1 AT E242247 T1 ATE242247 T1 AT E242247T1 AT 96932007 T AT96932007 T AT 96932007T AT 96932007 T AT96932007 T AT 96932007T AT E242247 T1 ATE242247 T1 AT E242247T1
Authority
AT
Austria
Prior art keywords
indole derivatives
medical use
present
antitussives
analgesics
Prior art date
Application number
AT96932007T
Other languages
English (en)
Inventor
Hiroshi Nagase
Koji Kawai
Takashi Endo
Shinya Ueno
Masayuki Maeda
Satoshi Sakami
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Application granted granted Critical
Publication of ATE242247T1 publication Critical patent/ATE242247T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT96932007T 1995-09-26 1996-09-26 Indolderivate und ihre medizinische verwendung ATE242247T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24747295 1995-09-26
PCT/JP1996/002791 WO1997011948A1 (fr) 1995-09-26 1996-09-26 Derives d'indole et leur utilisation medicinale

Publications (1)

Publication Number Publication Date
ATE242247T1 true ATE242247T1 (de) 2003-06-15

Family

ID=17163970

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96932007T ATE242247T1 (de) 1995-09-26 1996-09-26 Indolderivate und ihre medizinische verwendung

Country Status (13)

Country Link
US (1) US5849731A (de)
EP (1) EP0805157B1 (de)
JP (1) JP3123080B2 (de)
CN (1) CN1093862C (de)
AT (1) ATE242247T1 (de)
AU (1) AU712012B2 (de)
CA (1) CA2205664C (de)
DE (1) DE69628543T2 (de)
ES (1) ES2197953T3 (de)
NO (1) NO972377L (de)
PT (1) PT805157E (de)
TW (1) TW344742B (de)
WO (1) WO1997011948A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3605825B2 (ja) 1992-09-29 2004-12-22 東レ株式会社 インドール誘導体，その製造方法およびその医薬用途
ES2308990T3 (es) * 1999-08-24 2008-12-16 Toray Industries, Inc. Remedios para el dolor neuropatico y modelos animales de dolor neuropatico.
AU2408602A (en) * 2000-11-22 2002-06-03 Toray Industries Indole derivatives and use thereof in medicines
CN1758912A (zh) * 2003-03-07 2006-04-12 东丽株式会社 药物·物质依赖治疗药
WO2005075455A2 (en) * 2004-01-30 2005-08-18 Euro-Celtique S.A. Methods for making 4-tetrazolyl-4-phenylpiperidine compounds
JPWO2006064780A1 (ja) * 2004-12-14 2008-06-12 塩野義製薬株式会社 便秘治療剤
WO2008001859A1 (fr) * 2006-06-30 2008-01-03 School Juridical Person Kitasato Gakuen AGONISTE DES RÉCEPTEURS δ DES OPIOÏDES
JP5213157B2 (ja) * 2007-08-24 2013-06-19 学校法人北里研究所 ６，１４−エポキシモルヒナン誘導体およびその医薬用途
US9969746B2 (en) 2013-12-05 2018-05-15 The University Of Bath Opioid compounds and their uses
CA3091752A1 (en) 2018-03-08 2019-09-12 Victoria Link Ltd Treatment of demyelinating diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816586A (en) * 1987-07-29 1989-03-28 Regents Of The University Of Minnesota Delta opioid receptor antagonists
US5223625A (en) * 1988-12-22 1993-06-29 Duphar International Research B.V. Annelated indolo [3,2,-C]lactams
US5225417A (en) * 1992-01-21 1993-07-06 G. D. Searle & Co. Opioid agonist compounds
US5354863A (en) * 1992-01-21 1994-10-11 G. D. Searle & Co. Opioid agonist compounds
JP3605825B2 (ja) * 1992-09-29 2004-12-22 東レ株式会社 インドール誘導体，その製造方法およびその医薬用途
US5714483A (en) * 1992-12-22 1998-02-03 Toray Industries, Inc. Antitussive
US5457208A (en) * 1993-06-21 1995-10-10 Regents Of The University Of Minnesota Kappa opioid receptor antagonists
US5411965A (en) * 1993-08-23 1995-05-02 Arizona Board Of Regents Use of delta opioid receptor antagonists to treat cocaine abuse
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
SE9401728D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds II
SE9401727D0 (sv) * 1994-05-18 1994-05-18 Astra Ab New compounds I

Also Published As

Publication number Publication date
TW344742B (en) 1998-11-11
DE69628543T2 (de) 2003-12-11
US5849731A (en) 1998-12-15
EP0805157B1 (de) 2003-06-04
EP0805157A4 (de) 1999-01-07
ES2197953T3 (es) 2004-01-16
NO972377L (no) 1997-07-23
CN1165517A (zh) 1997-11-19
AU712012B2 (en) 1999-10-28
NO972377D0 (no) 1997-05-23
WO1997011948A1 (fr) 1997-04-03
AU7096096A (en) 1997-04-17
EP0805157A1 (de) 1997-11-05
CA2205664C (en) 2008-05-20
CN1093862C (zh) 2002-11-06
CA2205664A1 (en) 1997-04-03
JP3123080B2 (ja) 2001-01-09
PT805157E (pt) 2003-10-31
DE69628543D1 (de) 2003-07-10

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