EA200100581A1 - Комбинация анальгетических лекарственных средств - Google Patents

Комбинация анальгетических лекарственных средств

Info

Publication number
EA200100581A1
EA200100581A1 EA200100581A EA200100581A EA200100581A1 EA 200100581 A1 EA200100581 A1 EA 200100581A1 EA 200100581 A EA200100581 A EA 200100581A EA 200100581 A EA200100581 A EA 200100581A EA 200100581 A1 EA200100581 A1 EA 200100581A1
Authority
EA
Eurasian Patent Office
Prior art keywords
methyl
analgesic
compound
analgin
theobromine
Prior art date
Application number
EA200100581A
Other languages
English (en)
Other versions
EA004375B1 (ru
Inventor
Петер Араньи
Аттила Б.Ковач
Жужанна Фюршт
Петерне Ковач
Эндре Микуш
Original Assignee
Хиноин Дьедьсер Еш Ведьесети Термекек Дьяра Рт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Хиноин Дьедьсер Еш Ведьесети Термекек Дьяра Рт. filed Critical Хиноин Дьедьсер Еш Ведьесети Термекек Дьяра Рт.
Publication of EA200100581A1 publication Critical patent/EA200100581A1/ru
Publication of EA004375B1 publication Critical patent/EA004375B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к фармацевтической композиции, включающей в качестве активного ингредиента анальгетическое соединение и соединение ксантиновой структуры, в которой соотношение анальгетика и ксантинового производного составляет (1-20):1, предпочтительно 10:1. В качестве анальгетического соединения используют предпочтительно морфин, аминофеназон, анальгин, ацетилсалициловую кислоту, индометацин, ибупрофен, диклофенак, кодеин, более предпочтительно анальгин, S(+)ибупрофен, диклофенак; в качестве соединения ксантиновой структуры используют 3-метилксантин, теобромин или СН-13584 (1H-пурин-2,6-дион-3,7-дигидро-3-метил-7/5-метил-1,2,4-оксади-азол-2-ил/метил), предпочтительно теобромин. Композиции по настоящему изобретению могут содержать в качестве дополнительного активного ингредиента спазмолитик, предпочтительно дротаверин.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100581A 1998-11-25 1999-11-23 Комбинация анальгетических лекарственных средств EA004375B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9802716A HUP9802716A3 (en) 1998-11-25 1998-11-25 Pharmaceutical composition of analgesic activity
PCT/HU1999/000079 WO2000030715A1 (en) 1998-11-25 1999-11-23 Composition containing an analgesic and a xanthine or a xanthine derivative

Publications (2)

Publication Number Publication Date
EA200100581A1 true EA200100581A1 (ru) 2001-12-24
EA004375B1 EA004375B1 (ru) 2004-04-29

Family

ID=89997413

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100581A EA004375B1 (ru) 1998-11-25 1999-11-23 Комбинация анальгетических лекарственных средств

Country Status (12)

Country Link
EP (1) EP1131135A1 (ru)
AU (1) AU1510200A (ru)
BG (1) BG105616A (ru)
CZ (1) CZ20011847A3 (ru)
EA (1) EA004375B1 (ru)
EE (1) EE200100281A (ru)
HR (1) HRP20010403A2 (ru)
HU (1) HUP9802716A3 (ru)
PL (1) PL348631A1 (ru)
SK (1) SK6872001A3 (ru)
WO (1) WO2000030715A1 (ru)
YU (1) YU37001A (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BG65576B1 (bg) * 2002-04-17 2009-01-30 ПИРИМОВА Румяна Състав на болкоуспокояващо средство, по-специалнопри главоболие и мигрена
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0919893D0 (en) * 2009-11-13 2009-12-30 Biocopea Ltd Drug composition and its use in therapy
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
AU2015201845B2 (en) * 2009-11-13 2015-11-05 Infirst Healthcare Limited Drug combination with theobromine and its use in therapy
WO2013005226A1 (en) * 2011-07-04 2013-01-10 Zota Health Care Ltd A novel combined pharmaceutical composition containing diclofenac and methods of making and using the same
US8853189B2 (en) 2012-05-31 2014-10-07 Prima Innovations, Llc Antispasmodic 1,2-Diols and 1,2,3-triols

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986003681A1 (en) * 1984-12-26 1986-07-03 Abraham Sunshine Analgesic, anti-inflammatory and skeletal muscle relaxant compositions
WO1995007103A1 (en) * 1993-09-07 1995-03-16 The Procter & Gamble Company Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
GB9613457D0 (en) * 1996-06-27 1996-08-28 Procter & Gamble Pharmaceutical compositions

Also Published As

Publication number Publication date
HRP20010403A2 (en) 2002-06-30
EP1131135A1 (en) 2001-09-12
WO2000030715A1 (en) 2000-06-02
EA004375B1 (ru) 2004-04-29
HUP9802716A2 (hu) 2000-06-28
CZ20011847A3 (cs) 2002-07-17
PL348631A1 (en) 2002-06-03
YU37001A (sh) 2004-05-12
HUP9802716A3 (en) 2000-08-28
AU1510200A (en) 2000-06-13
SK6872001A3 (en) 2002-05-09
EE200100281A (et) 2002-08-15
BG105616A (en) 2002-01-31
HU9802716D0 (en) 1999-01-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU