ATE77236T1 - Pharmazeutische zusammensetzungen. - Google Patents

Pharmazeutische zusammensetzungen.

Info

Publication number
ATE77236T1
ATE77236T1 AT88202909T AT88202909T ATE77236T1 AT E77236 T1 ATE77236 T1 AT E77236T1 AT 88202909 T AT88202909 T AT 88202909T AT 88202909 T AT88202909 T AT 88202909T AT E77236 T1 ATE77236 T1 AT E77236T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
present
esters
cimetidine
bioavailability
Prior art date
Application number
AT88202909T
Other languages
English (en)
Inventor
Eberhard Fritz Gottwald
Hermann Peter Osterwald
Horst Manfred Machoczek
David Mayron
Original Assignee
Smithkline Dauelsberg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Dauelsberg filed Critical Smithkline Dauelsberg
Application granted granted Critical
Publication of ATE77236T1 publication Critical patent/ATE77236T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT88202909T 1987-12-23 1988-12-16 Pharmazeutische zusammensetzungen. ATE77236T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878730011A GB8730011D0 (en) 1987-12-23 1987-12-23 Pharmaceutical compositions
EP88202909A EP0322048B1 (de) 1987-12-23 1988-12-16 Pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE77236T1 true ATE77236T1 (de) 1992-07-15

Family

ID=10628958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88202909T ATE77236T1 (de) 1987-12-23 1988-12-16 Pharmazeutische zusammensetzungen.

Country Status (15)

Country Link
US (1) US5057319A (de)
EP (1) EP0322048B1 (de)
JP (1) JP2840097B2 (de)
AT (1) ATE77236T1 (de)
AU (1) AU605671B2 (de)
CA (1) CA1313140C (de)
DE (1) DE3872199T2 (de)
DK (1) DK415689A (de)
ES (1) ES2042723T3 (de)
GB (1) GB8730011D0 (de)
GR (1) GR3005640T3 (de)
IE (1) IE60966B1 (de)
PT (1) PT89260B (de)
WO (1) WO1989005640A1 (de)
ZA (1) ZA889441B (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578322A (en) * 1990-11-30 1996-11-26 Yamanouchi Pharmaceutical Co., Ltd. Quick release coated preparation
US5629013A (en) * 1991-04-04 1997-05-13 The Procter & Gamble Company Chewable calcium carbonate antacid tablet compositions
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
ES2202302T3 (es) * 1991-05-28 2004-04-01 Mcneil-Ppc, Inc. Composicion masticable que libera un farmaco.
GB9127150D0 (en) * 1991-12-20 1992-02-19 Smithkline Beecham Plc Novel treatment
AU2584092A (en) * 1992-09-03 1994-03-29 Affinity Biotech, Inc. Taste-masking pharmaceutical compositions and methods for making the same
JPH08510989A (ja) * 1992-10-16 1996-11-19 グラクソ、グループ、リミテッド ラニチジン組成物
GB9224855D0 (en) * 1992-11-27 1993-01-13 Smithkline Beecham Plc Pharmaceutical compositions
KR0168715B1 (ko) * 1992-11-30 1999-01-15 밋첼 아이. 커시너 맛을 차단하는 약제학적 조성물
US5622980A (en) * 1993-08-17 1997-04-22 Applied Analytical Industries, Inc. Oral compositions of H2-antagonists
JP3601071B2 (ja) * 1994-03-11 2004-12-15 不二製油株式会社 ブルーム防止剤並びにこれを含有するラウリン系油脂及びチョコレート類
AUPN862596A0 (en) * 1996-03-12 1996-04-04 F.H. Faulding & Co. Limited Pharmaceutical compositions
US6537525B1 (en) * 1997-01-29 2003-03-25 Douglas H. West Medicated chewing-gum
EP1020193A4 (de) * 1997-09-30 2006-05-24 Daiichi Seiyaku Co Orale präparation
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
FR2784895B1 (fr) * 1998-10-23 2004-12-17 Gattefosse Ets Sa Comprime a croquer a gout masque et liberation immediate du principe actif et procede de fabrication
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CA2424770A1 (en) 2000-10-06 2003-04-03 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation
US20040115287A1 (en) * 2002-12-17 2004-06-17 Lipocine, Inc. Hydrophobic active agent compositions and methods
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
EP2063861B1 (de) * 2006-09-15 2015-02-25 Echo Pharmaceuticals B.V. Dosiereinheit zur sublingualen, bukkalen oder oralen verabreichung von wasserunlöslichen pharmazeutischen wirkstoffen
US20100034888A1 (en) * 2006-09-15 2010-02-11 Hubert Clemens Pellikaan Granulate containing a pharmaceutically active substance and method for its manufacture
US9375437B2 (en) 2010-06-18 2016-06-28 Lipocine Inc. Progesterone containing oral dosage forms and kits
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
US8951996B2 (en) 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
EP3310359A4 (de) 2015-06-22 2019-04-03 Lipocine Inc. 17-hydroxyprogesteronesterhaltige orale zusammensetzungen und zugehörige verfahren
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3308217A (en) * 1965-02-09 1967-03-07 Lowy Lawrence Method of granulating materials for subsequent forming into tablets
FR2253507A1 (en) * 1973-12-11 1975-07-04 Houdet Antoine Vincamine administration using delayed release excipient - allowing prolonged action
US4256108A (en) * 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
JPS6029682B2 (ja) * 1980-07-11 1985-07-12 山之内製薬株式会社 苦味のない製剤用組成物およびその製造法
MTP930B (en) * 1982-04-30 1984-04-10 Delandale Labs Ltd Substained release lithium-containing tablets and method for their manufacture
US4851228A (en) * 1984-06-20 1989-07-25 Merck & Co., Inc. Multiparticulate controlled porosity osmotic
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3524003A1 (de) * 1985-07-04 1987-01-08 Heumann Ludwig & Co Gmbh Arzneimittelgranulat mit verzoegerter wirkstofffreisetzung und verfahren zu seiner herstellung
FR2593065B1 (fr) * 1986-01-22 1988-09-09 Smith Kline French Lab Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation.
US4786502A (en) * 1986-10-06 1988-11-22 The Procter & Gamble Company Palatable solid pharmaceutical compositions
GB2195890A (en) * 1986-10-06 1988-04-20 Procter & Gamble Improving palatability of pharmaceutical chewable tablets
GB2195891A (en) * 1986-10-06 1988-04-20 Procter & Gamble Improving palatability of pharmaceutical chewable tablets
US4892778A (en) * 1987-05-27 1990-01-09 Alza Corporation Juxtaposed laminated arrangement
US4824675A (en) * 1987-07-13 1989-04-25 Alza Corporation Dispenser with movable matrix comprising a plurality of tiny pills
US4814183A (en) * 1987-08-31 1989-03-21 Merck & Co., Inc. Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins
DE68903605T2 (de) * 1988-05-04 1993-04-01 Smith Kline French Lab Kautablette.

Also Published As

Publication number Publication date
DE3872199T2 (de) 1992-12-17
JPH02502729A (ja) 1990-08-30
IE883843L (en) 1989-06-23
DK415689D0 (da) 1989-08-23
ZA889441B (en) 1989-12-27
DE3872199D1 (de) 1992-07-23
PT89260A (pt) 1989-12-29
WO1989005640A1 (en) 1989-06-29
AU2915789A (en) 1989-07-19
GR3005640T3 (de) 1993-06-07
IE60966B1 (en) 1994-09-07
GB8730011D0 (en) 1988-02-03
AU605671B2 (en) 1991-01-17
JP2840097B2 (ja) 1998-12-24
PT89260B (pt) 1993-07-30
ES2042723T3 (es) 1993-12-16
DK415689A (da) 1989-08-23
EP0322048B1 (de) 1992-06-17
CA1313140C (en) 1993-01-26
EP0322048A1 (de) 1989-06-28
US5057319A (en) 1991-10-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time