ES2042723T3 - Un procedimiento para preparar una composicion farmaceutica granular. - Google Patents
Un procedimiento para preparar una composicion farmaceutica granular.Info
- Publication number
- ES2042723T3 ES2042723T3 ES88202909T ES88202909T ES2042723T3 ES 2042723 T3 ES2042723 T3 ES 2042723T3 ES 88202909 T ES88202909 T ES 88202909T ES 88202909 T ES88202909 T ES 88202909T ES 2042723 T3 ES2042723 T3 ES 2042723T3
- Authority
- ES
- Spain
- Prior art keywords
- preparing
- procedure
- pharmaceutical composition
- granular pharmaceutical
- taste
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical class OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 1
- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 abstract 1
- 229960001380 cimetidine Drugs 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A UN COMPUESTO FARMACEUTICO GRANULAR QUE COMPRENDE CIMETIDINA Y COMO AGENTE GRAQNUILANTE Y AGENTE QUE ENMASCARA EL SABOR UN ESTER DE UN COMPUESTO POLIHIDROXIL, Y DONDE SE DESEA UNA EMULSION SABROSA ACEPTABLE FARMACEUTICAMENTE. LOS ESTERES EN PARTICULAR SON ESTERES DE GLICEROL. LOS GRANULOS DE LA PRESXENTE INVENCION PUEDEN UTILIZARSE EN LA PREPARACION DE PASTILLAS QUE TIENEN UNA BUENA BIOEFICACIA Y SABOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878730011A GB8730011D0 (en) | 1987-12-23 | 1987-12-23 | Pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2042723T3 true ES2042723T3 (es) | 1993-12-16 |
Family
ID=10628958
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88202909T Expired - Lifetime ES2042723T3 (es) | 1987-12-23 | 1988-12-16 | Un procedimiento para preparar una composicion farmaceutica granular. |
Country Status (15)
Country | Link |
---|---|
US (1) | US5057319A (es) |
EP (1) | EP0322048B1 (es) |
JP (1) | JP2840097B2 (es) |
AT (1) | ATE77236T1 (es) |
AU (1) | AU605671B2 (es) |
CA (1) | CA1313140C (es) |
DE (1) | DE3872199T2 (es) |
DK (1) | DK415689A (es) |
ES (1) | ES2042723T3 (es) |
GB (1) | GB8730011D0 (es) |
GR (1) | GR3005640T3 (es) |
IE (1) | IE60966B1 (es) |
PT (1) | PT89260B (es) |
WO (1) | WO1989005640A1 (es) |
ZA (1) | ZA889441B (es) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5578322A (en) * | 1990-11-30 | 1996-11-26 | Yamanouchi Pharmaceutical Co., Ltd. | Quick release coated preparation |
US5629013A (en) * | 1991-04-04 | 1997-05-13 | The Procter & Gamble Company | Chewable calcium carbonate antacid tablet compositions |
ATE245023T1 (de) * | 1991-05-28 | 2003-08-15 | Mcneil Ppc Inc | Kaubare zusammensetzung zur arzneimittelfreisetzung |
US5380535A (en) * | 1991-05-28 | 1995-01-10 | Geyer; Robert P. | Chewable drug-delivery compositions and methods for preparing the same |
GB9127150D0 (en) * | 1991-12-20 | 1992-02-19 | Smithkline Beecham Plc | Novel treatment |
EP0663818A4 (en) * | 1992-09-03 | 1996-04-24 | Ibah Inc | TASTE-COVERING PHARMACEUTICAL SUMMARY AND METHOD FOR PRODUCING THE SAME. |
MX9306393A (es) * | 1992-10-16 | 1994-04-29 | Glaxo Group Ltd | Composiciones de ranitidina substancialmente libres de sabor amargo, proceso para su preparacion y composiciones farmaceuticas que las contienen. |
GB9224855D0 (en) * | 1992-11-27 | 1993-01-13 | Smithkline Beecham Plc | Pharmaceutical compositions |
CA2150119C (en) * | 1992-11-30 | 2005-03-15 | Robert C. Cuca | Tastemasked pharmaceutical materials |
US5622980A (en) * | 1993-08-17 | 1997-04-22 | Applied Analytical Industries, Inc. | Oral compositions of H2-antagonists |
JP3601071B2 (ja) * | 1994-03-11 | 2004-12-15 | 不二製油株式会社 | ブルーム防止剤並びにこれを含有するラウリン系油脂及びチョコレート類 |
AUPN862596A0 (en) * | 1996-03-12 | 1996-04-04 | F.H. Faulding & Co. Limited | Pharmaceutical compositions |
US6537525B1 (en) * | 1997-01-29 | 2003-03-25 | Douglas H. West | Medicated chewing-gum |
CN1152717C (zh) * | 1997-09-30 | 2004-06-09 | 第一制药株式会社 | 口服给药制剂 |
US5891476A (en) * | 1997-12-22 | 1999-04-06 | Reo; Joe P. | Tastemasked pharmaceutical system |
FR2784895B1 (fr) * | 1998-10-23 | 2004-12-17 | Gattefosse Ets Sa | Comprime a croquer a gout masque et liberation immediate du principe actif et procede de fabrication |
US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US7510728B2 (en) | 2000-10-06 | 2009-03-31 | Takeda Pharmaceutical Company Limited | Solid preparations |
US20040115287A1 (en) * | 2002-12-17 | 2004-06-17 | Lipocine, Inc. | Hydrophobic active agent compositions and methods |
US7282217B1 (en) | 2003-08-29 | 2007-10-16 | Kv Pharmaceutical Company | Rapidly disintegrable tablets |
AU2007295178B2 (en) * | 2006-09-15 | 2013-04-18 | Echo Pharmaceuticals B.V. | Granulate containing a pharmaceutically active substance and anemulsifier and method for its manufacture |
WO2008033024A2 (en) * | 2006-09-15 | 2008-03-20 | Echo Pharmaceuticals B.V. | Dosage unit for sublingual, buccal or oral administration of water-insoluble pharmaceutically active substances |
US9375437B2 (en) | 2010-06-18 | 2016-06-28 | Lipocine Inc. | Progesterone containing oral dosage forms and kits |
US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
US8951996B2 (en) | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
WO2016033549A2 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
BR112017027688A2 (pt) | 2015-06-22 | 2018-09-04 | Lipocine Inc | Composições orais que contêm éster de 17- hidroxiprogesterona e métodos relacionados |
US20180147215A1 (en) | 2016-11-28 | 2018-05-31 | Lipocine Inc. | Oral testosterone undecanoate therapy |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3308217A (en) * | 1965-02-09 | 1967-03-07 | Lowy Lawrence | Method of granulating materials for subsequent forming into tablets |
FR2253507A1 (en) * | 1973-12-11 | 1975-07-04 | Houdet Antoine | Vincamine administration using delayed release excipient - allowing prolonged action |
US4256108A (en) * | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
JPS6029682B2 (ja) * | 1980-07-11 | 1985-07-12 | 山之内製薬株式会社 | 苦味のない製剤用組成物およびその製造法 |
MTP930B (en) * | 1982-04-30 | 1984-04-10 | Delandale Labs Ltd | Substained release lithium-containing tablets and method for their manufacture |
US4851228A (en) * | 1984-06-20 | 1989-07-25 | Merck & Co., Inc. | Multiparticulate controlled porosity osmotic |
US4755387A (en) * | 1985-03-21 | 1988-07-05 | The Procter & Gamble Company | Therapeutic particles |
DE3524003A1 (de) * | 1985-07-04 | 1987-01-08 | Heumann Ludwig & Co Gmbh | Arzneimittelgranulat mit verzoegerter wirkstofffreisetzung und verfahren zu seiner herstellung |
FR2593065B1 (fr) * | 1986-01-22 | 1988-09-09 | Smith Kline French Lab | Couples effervescents, compositions effervescentes d'antagonistes h2 de l'histamine les contenant et leur preparation. |
US4786502A (en) * | 1986-10-06 | 1988-11-22 | The Procter & Gamble Company | Palatable solid pharmaceutical compositions |
GB2195891A (en) * | 1986-10-06 | 1988-04-20 | Procter & Gamble | Improving palatability of pharmaceutical chewable tablets |
GB2195890A (en) * | 1986-10-06 | 1988-04-20 | Procter & Gamble | Improving palatability of pharmaceutical chewable tablets |
US4892778A (en) * | 1987-05-27 | 1990-01-09 | Alza Corporation | Juxtaposed laminated arrangement |
US4824675A (en) * | 1987-07-13 | 1989-04-25 | Alza Corporation | Dispenser with movable matrix comprising a plurality of tiny pills |
US4814183A (en) * | 1987-08-31 | 1989-03-21 | Merck & Co., Inc. | Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins |
ES2052911T3 (es) * | 1988-05-04 | 1994-07-16 | Smith Kline French Lab | Tableta masticable. |
-
1987
- 1987-12-23 GB GB878730011A patent/GB8730011D0/en active Pending
-
1988
- 1988-12-16 ES ES88202909T patent/ES2042723T3/es not_active Expired - Lifetime
- 1988-12-16 EP EP88202909A patent/EP0322048B1/en not_active Expired - Lifetime
- 1988-12-16 WO PCT/EP1988/001189 patent/WO1989005640A1/en unknown
- 1988-12-16 DE DE8888202909T patent/DE3872199T2/de not_active Expired - Lifetime
- 1988-12-16 AT AT88202909T patent/ATE77236T1/de not_active IP Right Cessation
- 1988-12-16 JP JP1501032A patent/JP2840097B2/ja not_active Expired - Lifetime
- 1988-12-16 AU AU29157/89A patent/AU605671B2/en not_active Expired
- 1988-12-19 ZA ZA889441A patent/ZA889441B/xx unknown
- 1988-12-19 PT PT89260A patent/PT89260B/pt not_active IP Right Cessation
- 1988-12-20 US US07/287,194 patent/US5057319A/en not_active Expired - Lifetime
- 1988-12-22 IE IE384388A patent/IE60966B1/en not_active IP Right Cessation
- 1988-12-22 CA CA000586773A patent/CA1313140C/en not_active Expired - Lifetime
-
1989
- 1989-08-23 DK DK415689A patent/DK415689A/da not_active Application Discontinuation
-
1992
- 1992-09-07 GR GR920401972T patent/GR3005640T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0322048A1 (en) | 1989-06-28 |
PT89260B (pt) | 1993-07-30 |
GB8730011D0 (en) | 1988-02-03 |
PT89260A (pt) | 1989-12-29 |
JP2840097B2 (ja) | 1998-12-24 |
DK415689D0 (da) | 1989-08-23 |
WO1989005640A1 (en) | 1989-06-29 |
ZA889441B (en) | 1989-12-27 |
JPH02502729A (ja) | 1990-08-30 |
US5057319A (en) | 1991-10-15 |
IE883843L (en) | 1989-06-23 |
AU2915789A (en) | 1989-07-19 |
EP0322048B1 (en) | 1992-06-17 |
CA1313140C (en) | 1993-01-26 |
AU605671B2 (en) | 1991-01-17 |
IE60966B1 (en) | 1994-09-07 |
ATE77236T1 (de) | 1992-07-15 |
GR3005640T3 (es) | 1993-06-07 |
DE3872199D1 (de) | 1992-07-23 |
DE3872199T2 (de) | 1992-12-17 |
DK415689A (da) | 1989-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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