NO941589L - - Google Patents
Info
- Publication number
- NO941589L NO941589L NO941589A NO941589A NO941589L NO 941589 L NO941589 L NO 941589L NO 941589 A NO941589 A NO 941589A NO 941589 A NO941589 A NO 941589A NO 941589 L NO941589 L NO 941589L
- Authority
- NO
- Norway
- Prior art keywords
- lower alkyl
- alkyl
- perhaloalkyl
- stars
- alkanoyl
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 1
- 125000002861 (C1-C4) alkanoyl group Chemical group 0.000 abstract 1
- 125000006374 C2-C10 alkenyl group Chemical group 0.000 abstract 1
- 206010017533 Fungal infection Diseases 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000031888 Mycoses Diseases 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78535791A | 1991-10-30 | 1991-10-30 | |
| US90726292A | 1992-07-01 | 1992-07-01 | |
| PCT/US1992/008981 WO1993009114A1 (en) | 1991-10-30 | 1992-10-28 | Tri-substituted tetrahydrofuran antifungals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO941589D0 NO941589D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-04-29 |
| NO941589L true NO941589L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-06-23 |
Family
ID=27120397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO941589A NO941589L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1991-10-30 | 1994-04-29 |
Country Status (22)
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5403937A (en) * | 1993-04-30 | 1995-04-04 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| US5349099A (en) * | 1993-12-13 | 1994-09-20 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| US5693626A (en) * | 1993-12-21 | 1997-12-02 | Schering Corporation | Tetrahydrofuran antifungals |
| US5714490A (en) * | 1993-12-21 | 1998-02-03 | Schering Corporation | Tetrahydrofuran antifungals |
| ATE204875T1 (de) * | 1993-12-21 | 2001-09-15 | Schering Corp | Fungizide tetrahydrofurane |
| US5661151A (en) * | 1993-12-21 | 1997-08-26 | Schering Corporation | Tetrahydrofuran antifungals |
| US5703236A (en) * | 1993-12-21 | 1997-12-30 | Schering Corporation | Tetrahydrofuran antifungals |
| US5703079A (en) * | 1993-12-21 | 1997-12-30 | Schering Corporation | Tetrahydrofuran antifungals |
| US5710154A (en) * | 1993-12-21 | 1998-01-20 | Schering Corporation | Tetrahydrofuran antifungals |
| PT741737E (pt) * | 1994-01-24 | 2000-04-28 | Janssen Pharmaceutica Nv | Antifungicos do tipo azole soluveis em agua |
| US5654472A (en) * | 1994-04-19 | 1997-08-05 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Triazole derivatives |
| US5442093A (en) * | 1994-05-09 | 1995-08-15 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
| US5486625A (en) * | 1994-07-08 | 1996-01-23 | Schering Corporation | Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents |
| WO1996002664A1 (fr) * | 1994-07-18 | 1996-02-01 | Daicel Chemical Industries, Ltd. | Procede pour produire et racemiser un compose triazole optiquement actif |
| US5616777A (en) * | 1995-04-19 | 1997-04-01 | Schering Corporation | Chiral hydrazine derivatives |
| US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
| CZ59497A3 (en) * | 1995-06-02 | 1997-08-13 | Schering Corp | Tetrahydrofuran derivative and pharmaceutical composition containing thereof |
| US5698557A (en) * | 1995-06-19 | 1997-12-16 | Schering Corporation | Hydroxy-substituted antifungals |
| ATE247108T1 (de) * | 1995-06-19 | 2003-08-15 | Schering Corp | Antifungale tetrahydrofurane |
| US5834472A (en) * | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
| US5846971A (en) * | 1996-06-28 | 1998-12-08 | Schering Corporation | Oral antifungal composition |
| TW593312B (en) * | 1997-07-11 | 2004-06-21 | Janssen Pharmaceutica Nv | 2,4,4-trisubstituted-1,3-dioxolane antifungals |
| CO4970829A1 (es) * | 1997-10-07 | 2000-11-07 | Schering Corp | Polimorfo antifungico cristalino |
| BR0215702A (pt) * | 2002-04-12 | 2005-10-18 | Ranbaxy Lab Ltd | Derivados de tetraidrofurano 2,2,4-trisubstituìdo como agentes antifúngicos |
| US9073904B2 (en) | 2010-05-19 | 2015-07-07 | Sandoz Ag | Preparation of posaconazole intermediates |
| MX337804B (es) | 2010-05-19 | 2016-03-18 | Sandoz Ag | Proceso para la preparacion de hidrazinas quirales. |
| AU2011254654B2 (en) | 2010-05-19 | 2016-01-07 | Sandoz Ag | Process for the preparation of chiral triazolones |
| AU2011254658B2 (en) | 2010-05-19 | 2016-02-18 | Sandoz Ag | Purification of posaconazole and of posaconazole intermediates |
| WO2012172015A1 (en) | 2011-06-16 | 2012-12-20 | Sandoz Ag | Process for the preparation of a chiral compound |
| WO2014197738A1 (en) * | 2013-06-07 | 2014-12-11 | The California Institute For Biomedical Research | Small molecule inhibitors of fibrosis |
| CN106397417A (zh) * | 2016-08-30 | 2017-02-15 | 甘肃皓天化学科技有限公司 | 用于制备泊沙康唑的中间体的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4267179A (en) * | 1978-06-23 | 1981-05-12 | Janssen Pharmaceutica, N.V. | Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles |
| US4619931A (en) * | 1983-02-28 | 1986-10-28 | Janssen Pharmaceutica, N.V. | [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles |
| DE3346123A1 (de) | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| US4727064A (en) | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
| DK354185A (da) * | 1984-08-31 | 1986-03-01 | Hoffmann La Roche | 1,3-dioxolanderivater |
| NZ223799A (en) * | 1987-03-25 | 1989-12-21 | Janssen Pharmaceutica Nv | Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions |
| US5006513A (en) | 1987-11-09 | 1991-04-09 | Miles Inc. | Antimycotic compositions of nikkomycin compounds and azole antimycotica |
| ES2065340T3 (es) * | 1987-11-20 | 1995-02-16 | Schering Corp | Oxetanos y tetrahidrofuranos tri- y tetra-sustituidos y compuestos intermedios para los mismos. |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| CA1331757C (en) * | 1988-02-29 | 1994-08-30 | Janssen Pharmaceutica Naamloze Vennootschap | 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols |
| NZ233502A (en) * | 1989-06-09 | 1991-11-26 | Janssen Pharmaceutica Nv | 4-(1,2,4-triazole- or imidazole-phenyl-substituted) -1-(1,3-dioxolan-4-ylmethoxyphenyl) piperazine derivatives; preparatory processes: fungicidal and antiviral compositions |
| US5039676A (en) | 1990-05-11 | 1991-08-13 | Schering Corporation | Tri- and tetra-substituted-oxetanes and tetrahydrofurans and intermediates thereof |
| US20040220100A1 (en) | 2000-07-21 | 2004-11-04 | Essentia Biosystems, Inc. | Multi-component biological transport systems |
-
1992
- 1992-10-27 IL IL103558A patent/IL103558A0/xx unknown
- 1992-10-28 ES ES92923060T patent/ES2153364T3/es not_active Expired - Lifetime
- 1992-10-28 MY MYPI92001943A patent/MY109529A/en unknown
- 1992-10-28 CZ CZ941027A patent/CZ102794A3/cs unknown
- 1992-10-28 CA CA002122270A patent/CA2122270C/en not_active Expired - Lifetime
- 1992-10-28 NZ NZ244910A patent/NZ244910A/en unknown
- 1992-10-28 EP EP92118413A patent/EP0539938A1/en active Pending
- 1992-10-28 JP JP50846493A patent/JP3210017B2/ja not_active Expired - Fee Related
- 1992-10-28 MX MX9206222A patent/MX9206222A/es unknown
- 1992-10-28 SK SK488-94A patent/SK48894A3/sk unknown
- 1992-10-28 HU HU9401256A patent/HUT70742A/hu unknown
- 1992-10-28 WO PCT/US1992/008981 patent/WO1993009114A1/en active IP Right Grant
- 1992-10-28 SG SG1996000735A patent/SG42920A1/en unknown
- 1992-10-28 DE DE69231661T patent/DE69231661T2/de not_active Expired - Lifetime
- 1992-10-28 AT AT92923060T patent/ATE198888T1/de active
- 1992-10-28 AU AU29169/92A patent/AU665218B2/en not_active Ceased
- 1992-10-28 EP EP92923060A patent/EP0610377B1/en not_active Expired - Lifetime
- 1992-10-29 SI SI19929200285A patent/SI9200285A/sl unknown
- 1992-10-29 YU YU94792A patent/YU94792A/sh unknown
- 1992-10-29 CN CN92113399A patent/CN1037267C/zh not_active Expired - Fee Related
- 1992-10-29 HR HR921145A patent/HRP921145A2/hr not_active Application Discontinuation
-
1994
- 1994-04-29 NO NO941589A patent/NO941589L/no unknown
- 1994-04-29 FI FI941986A patent/FI941986A7/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE198888T1 (de) | 2001-02-15 |
| FI941986A0 (fi) | 1994-04-29 |
| CA2122270A1 (en) | 1993-05-13 |
| ES2153364T3 (es) | 2001-03-01 |
| EP0610377A1 (en) | 1994-08-17 |
| DE69231661T2 (de) | 2001-08-02 |
| JPH07500605A (ja) | 1995-01-19 |
| EP0610377B1 (en) | 2001-01-24 |
| HUT70742A (en) | 1995-10-30 |
| SG42920A1 (en) | 1997-10-17 |
| JP3210017B2 (ja) | 2001-09-17 |
| CN1037267C (zh) | 1998-02-04 |
| AU2916992A (en) | 1993-06-07 |
| DE69231661D1 (de) | 2001-03-01 |
| CA2122270C (en) | 2006-05-23 |
| CZ102794A3 (en) | 1995-03-15 |
| SK48894A3 (en) | 1995-02-08 |
| YU94792A (sh) | 1995-12-04 |
| IL103558A0 (en) | 1993-03-15 |
| MX9206222A (es) | 1993-04-01 |
| EP0539938A1 (en) | 1993-05-05 |
| AU665218B2 (en) | 1995-12-21 |
| NZ244910A (en) | 1996-01-26 |
| CN1073944A (zh) | 1993-07-07 |
| FI941986A7 (fi) | 1994-04-29 |
| WO1993009114A1 (en) | 1993-05-13 |
| MY109529A (en) | 1997-02-28 |
| SI9200285A (en) | 1993-06-30 |
| HU9401256D0 (en) | 1994-08-29 |
| NO941589D0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-04-29 |
| HRP921145A2 (en) | 1994-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO941589L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| NO950297L (no) | Prolinamidderivater | |
| CO4410321A1 (es) | Compuestos ciclicos condensados con funciones aminoacidas sustituidas y derivados ester de los mismos | |
| KR950017957A (ko) | 3, 4, 4-삼치환-피페리디닐-n-알킬카르복실레이트의 제법 및 중간체 | |
| ES537182A0 (es) | Procedimiento de obtencion de compuestos de 1-aril-2-(3-(4-trifluormetilestiril)-1,2,4-triazol-1-il)-1-c 1,2,4,-triazol-1-il-metil) etanol de efecto antifugal. | |
| BG62620B1 (bg) | Карбоциклични съединения | |
| DE59209663D1 (de) | Verfahren zur Herstellung eines Arzneimittels zur oralen oder topischen Verabreichung bei der Behandlung von Leishmaniasis | |
| DK0659427T3 (da) | 2-Phenyl-3-azoylbenzothiophener til forøgelse af thrombomodulinekspression | |
| ATE174508T1 (de) | Verwendung von bis (amidinobenzidazolen) zur herstellung eines medikamentes für die hemmung der retroviral integrase | |
| DK0456209T3 (da) | Bis(alkylsubstituerede-4-hydroxyphenylthio)alkananaloger som inhibitorer af kataraktdannelse | |
| KR890009389A (ko) | 바이러스를 억제시키는 방법 | |
| DE69131163D1 (de) | Asthma heilmittel | |
| SE8704872D0 (sv) | Improvements in or relating to fungicides | |
| DK360388D0 (da) | Laegemiddel til behandling af hjerteinsufficiens | |
| ATE226192T1 (de) | Penizillaminamid-derivate | |
| NO932937L (no) | Fremgangsmaate for rensing av brukte smoereoljer | |
| EP0582713A4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | ||
| ATE171451T1 (de) | Thiazole mit antiviraler wirkung | |
| NZ221330A (en) | Fungicidal compositions containing benzimidazole derivatives for use against benomyl-resistant fungi | |
| ITMO930019V0 (it) | Tavoletta filtro per cannule di gruppi di aspirazione dentistici. | |
| ATE384149T1 (de) | Hydrophilieadditive | |
| KR920000327A (ko) | 비스(3,5-디-알킬-4- 히드록시페닐티오) 메탄을 유효 성분으로 함유하는 고트리글리세리드혈증 치료용 제약 조성물 | |
| IT1141104B (it) | Acaricidi attivi contro le uova ibernanti | |
| TH14179A (th) | อนุพันธ์ของ n-(ไฮดรอกซิเอธิล) บิวเทนไดแอมีด | |
| MX9702853A (es) | Metodos para inhibir condiciones asociadas con el neuropeptido "y". |