ES2065340T3 - Oxetanos y tetrahidrofuranos tri- y tetra-sustituidos y compuestos intermedios para los mismos. - Google Patents
Oxetanos y tetrahidrofuranos tri- y tetra-sustituidos y compuestos intermedios para los mismos.Info
- Publication number
- ES2065340T3 ES2065340T3 ES88310904T ES88310904T ES2065340T3 ES 2065340 T3 ES2065340 T3 ES 2065340T3 ES 88310904 T ES88310904 T ES 88310904T ES 88310904 T ES88310904 T ES 88310904T ES 2065340 T3 ES2065340 T3 ES 2065340T3
- Authority
- ES
- Spain
- Prior art keywords
- substituted
- tetra
- tri
- oxethanes
- tetrahydrofuranes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
ESTA INVENCION TRATA DE ACETANOS TRI Y TETRA SUSTITUIDOS DE LA FORMULA(I) POR G; (-+) CIS Y (+-)TRANS - 2 - [4 - (4 ISOPROPILPIPERACINA - 1 - ILO)FENOXI)METILO] - 4 - (2,4 DIHALOFENILO) - 4 - 911H - 1,2,4 - TRIAZOL - 1 ILO)METILO]OXETANO Y TETRAHIDROFURANOS TRI Y TETRASUSTITUIDOS, Y SUS DERIVADOS RELACIONADOS QUE TENGAN ACTIVIDADES ANTIALERGICAS Y ANTIHONGOS , SU COMPOSICION FARMACEUTICA, METODOS PARA SU USO EN TRATAMIENTO O PREVENCION DE INFECCIONES SUSCEPTIBLES DE HONGOS Y REACCIONES ALERGICAS EN UN HUESPED INCLUYENDO LOS ANIMALES DE SANGRE CALIENTE ASI COMO LOS HUMANOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12350087A | 1987-11-20 | 1987-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2065340T3 true ES2065340T3 (es) | 1995-02-16 |
Family
ID=22409034
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES88310904T Expired - Lifetime ES2065340T3 (es) | 1987-11-20 | 1988-11-18 | Oxetanos y tetrahidrofuranos tri- y tetra-sustituidos y compuestos intermedios para los mismos. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0386143A1 (es) |
JP (2) | JPH0717634B2 (es) |
AT (1) | ATE115577T1 (es) |
AU (1) | AU2811689A (es) |
DE (1) | DE3852477T2 (es) |
ES (1) | ES2065340T3 (es) |
GR (1) | GR3015217T3 (es) |
HK (1) | HK186296A (es) |
WO (1) | WO1989004829A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5134152A (en) * | 1989-12-07 | 1992-07-28 | Sankyo Company, Limited | Oxetane derivatives and their use as anti-fungal or fungicidal agents |
IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
US5403937A (en) * | 1993-04-30 | 1995-04-04 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
US5349099A (en) * | 1993-12-13 | 1994-09-20 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
US5703079A (en) * | 1993-12-21 | 1997-12-30 | Schering Corporation | Tetrahydrofuran antifungals |
US5710154A (en) * | 1993-12-21 | 1998-01-20 | Schering Corporation | Tetrahydrofuran antifungals |
US5693626A (en) * | 1993-12-21 | 1997-12-02 | Schering Corporation | Tetrahydrofuran antifungals |
CZ294823B6 (cs) * | 1993-12-21 | 2005-03-16 | Schering Corporation | Fungicidní tetrahydrofurany |
US5661151A (en) * | 1993-12-21 | 1997-08-26 | Schering Corporation | Tetrahydrofuran antifungals |
US5714490A (en) * | 1993-12-21 | 1998-02-03 | Schering Corporation | Tetrahydrofuran antifungals |
US5703236A (en) * | 1993-12-21 | 1997-12-30 | Schering Corporation | Tetrahydrofuran antifungals |
US5442093A (en) * | 1994-05-09 | 1995-08-15 | Schering Corporation | Process for preparing intermediates for the synthesis of antifungal agents |
US5486625A (en) * | 1994-07-08 | 1996-01-23 | Schering Corporation | Process for the preparation of chiral intermediates useful for the synthesis of antifungal agents |
US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
US5616777A (en) * | 1995-04-19 | 1997-04-01 | Schering Corporation | Chiral hydrazine derivatives |
US5698557A (en) * | 1995-06-19 | 1997-12-16 | Schering Corporation | Hydroxy-substituted antifungals |
US5834472A (en) * | 1996-05-24 | 1998-11-10 | Schering Corporation | Antifungal composition with enhanced bioavailability |
US5846971A (en) * | 1996-06-28 | 1998-12-08 | Schering Corporation | Oral antifungal composition |
KR100342383B1 (ko) * | 1999-06-17 | 2002-12-06 | 한국화학연구원 | 이소옥사졸리딘 유도체, 그의 제조 방법 및 그를 포함하는 살균제 조성물 |
KR101415742B1 (ko) * | 2011-12-21 | 2014-07-04 | 영남대학교 산학협력단 | 6―아미노피리딘―3―올 유도체 또는 이의 약제학적 허용가능한 염 및 이를 유효성분으로 함유하는 혈관신생으로 인한 질환의 예방 또는 치료용 약학조성물 |
MX370412B (es) | 2014-12-05 | 2019-12-11 | Pulmocide Ltd | Compuesto antimicotico. |
KR102653821B1 (ko) | 2015-05-21 | 2024-04-02 | 풀모사이드 리미티드 | 항진균성 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-트리아졸-1-일)메틸)-5-(2,4-디플루오로페닐)테트라하이드로푸란-3-일)메톡시)-3-메틸페닐)피페라진-1-일)-n-(2-하이드록시사이클로헥실)벤즈아미드 또는 이의 약학적으로 허용가능한 염. |
CN105949278B (zh) * | 2016-03-30 | 2019-12-06 | 南京曼杰生物科技有限公司 | 一种取代的四氢呋喃水溶性衍生物及其应用 |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
CN115322182A (zh) * | 2022-08-23 | 2022-11-11 | 广西医科大学 | 一种氮唑类抗真菌化合物及其应用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS55125405A (en) * | 1979-03-22 | 1980-09-27 | Funakubo Hiroyasu | Posture discriminating system |
FR2458838A1 (fr) * | 1979-06-06 | 1981-01-02 | Thomson Csf | Dispositif de mesure de l'orientation relative de deux corps et systeme de reperage de direction correspondant |
US4456605A (en) | 1981-05-07 | 1984-06-26 | Janssen Pharmaceutica N.V. | Heterocyclic derivatives of [4-(piperazin-1-yl-phenyloxymethyl)-1,3-dioxolan-2-ylmethyl]-1H-imidazoles and 1H-1,2,4-triazoles |
GB2099818A (en) | 1981-06-06 | 1982-12-15 | Pfizer Ltd | Triazoles |
GB2115408B (en) | 1982-02-09 | 1985-10-16 | Ici Plc | Triazole and imidazole derivatives |
DE3370798D1 (en) | 1982-06-14 | 1987-05-14 | Ici Plc | Fungicidal or plant growth regulating triazolyl ethanols |
US4482558A (en) * | 1982-06-18 | 1984-11-13 | Pfizer Inc. | Antifungal amide and urea derivatives of (3-amino-2-aryl-2-hydroxyprop-1-yl)-1H-1,2,4-triazoles |
EP0106515B1 (en) * | 1982-09-30 | 1988-12-28 | Pfizer Limited | Triazole anti-fungal agents |
GB8306512D0 (en) * | 1983-03-09 | 1983-04-13 | Ici Plc | Heterocyclic compounds |
DE3402166A1 (de) * | 1984-01-23 | 1985-07-25 | Hoechst Ag, 6230 Frankfurt | Azolyl-aryl-alkanol-derivate, verfahren zu ihrer herstellung und ihre verwendung |
FR2597868B1 (fr) * | 1986-04-23 | 1988-09-02 | Rhone Poulenc Agrochimie | Composes a groupements triazole ou imidazole et tetrahydrofuranne, utilisation de ceux-ci a titre de fongicides et procedes de preparation |
FR2558834B1 (fr) * | 1984-01-26 | 1988-01-08 | Rhone Poulenc Agrochimie | Fongicides a groupes triazole et oligoether |
DK354185A (da) | 1984-08-31 | 1986-03-01 | Hoffmann La Roche | 1,3-dioxolanderivater |
FR2611714A2 (fr) * | 1986-04-23 | 1988-09-09 | Rhone Poulenc Agrochimie | Composes a groupements triazole ou imidazole et tetrahydrofuran, utilisation de ceux-ci a titre de fongicides et procedes de preparation |
FR2603039B1 (fr) * | 1986-08-22 | 1990-01-05 | Rhone Poulenc Agrochimie | Derives de 2,5-dihydrofuranne a groupe triazole ou imidazole, procede de preparation, utilisation comme fongicide |
FR2603036B1 (fr) * | 1986-08-22 | 1988-11-25 | Rhone Poulenc Agrochimie | Derives de 2,3-dihydrofuranne, leur procede de preparation, leur utilisation comme intermediaire pour la preparation de tetrahydrofuranne |
FR2603038B1 (fr) * | 1986-08-22 | 1988-11-25 | Rhone Poulenc Agrochimie | Procede de preparation de composes a groupes triazole et tetrahydrofuranne, nouveaux composes utilisables pour la preparation desdits composes |
-
1988
- 1988-11-18 JP JP1500271A patent/JPH0717634B2/ja not_active Expired - Lifetime
- 1988-11-18 ES ES88310904T patent/ES2065340T3/es not_active Expired - Lifetime
- 1988-11-18 AU AU28116/89A patent/AU2811689A/en not_active Abandoned
- 1988-11-18 AT AT88310904T patent/ATE115577T1/de not_active IP Right Cessation
- 1988-11-18 EP EP89900481A patent/EP0386143A1/en active Pending
- 1988-11-18 DE DE3852477T patent/DE3852477T2/de not_active Expired - Fee Related
- 1988-11-18 EP EP88310904A patent/EP0318214B1/en not_active Expired - Lifetime
- 1988-11-18 WO PCT/US1988/003987 patent/WO1989004829A1/en not_active Application Discontinuation
-
1994
- 1994-08-09 JP JP6217792A patent/JPH07196506A/ja active Pending
-
1995
- 1995-02-28 GR GR950400421T patent/GR3015217T3/el unknown
-
1996
- 1996-10-03 HK HK186296A patent/HK186296A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH07196506A (ja) | 1995-08-01 |
DE3852477T2 (de) | 1995-05-04 |
GR3015217T3 (en) | 1995-05-31 |
DE3852477D1 (de) | 1995-01-26 |
EP0386143A1 (en) | 1990-09-12 |
JPH0717634B2 (ja) | 1995-03-01 |
EP0318214B1 (en) | 1994-12-14 |
HK186296A (en) | 1996-10-11 |
JPH02504033A (ja) | 1990-11-22 |
EP0318214A1 (en) | 1989-05-31 |
AU2811689A (en) | 1989-06-14 |
ATE115577T1 (de) | 1994-12-15 |
WO1989004829A1 (en) | 1989-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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