NO933723D0 - Prodrug-estere av fenoliske 2-piperidino-1-alkanoler - Google Patents

Prodrug-estere av fenoliske 2-piperidino-1-alkanoler

Info

Publication number
NO933723D0
NO933723D0 NO1993933723A NO933723A NO933723D0 NO 933723 D0 NO933723 D0 NO 933723D0 NO 1993933723 A NO1993933723 A NO 1993933723A NO 933723 A NO933723 A NO 933723A NO 933723 D0 NO933723 D0 NO 933723D0
Authority
NO
Norway
Prior art keywords
alkanols
piperidino
phenolic
prodrug esters
prodrug
Prior art date
Application number
NO1993933723A
Other languages
English (en)
Norwegian (no)
Other versions
NO933723L (no
Inventor
Bertrand L Chenard
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO933723L publication Critical patent/NO933723L/no
Publication of NO933723D0 publication Critical patent/NO933723D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO1993933723A 1991-04-18 1993-10-15 Prodrug-estere av fenoliske 2-piperidino-1-alkanoler NO933723D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68727391A 1991-04-18 1991-04-18
PCT/US1992/002131 WO1992018502A1 (en) 1991-04-18 1992-03-24 Prodrug esters of phenolic 2-piperidino-1-alkanols

Publications (2)

Publication Number Publication Date
NO933723L NO933723L (no) 1993-10-15
NO933723D0 true NO933723D0 (no) 1993-10-15

Family

ID=24759771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO1993933723A NO933723D0 (no) 1991-04-18 1993-10-15 Prodrug-estere av fenoliske 2-piperidino-1-alkanoler

Country Status (19)

Country Link
US (3) US5455250A (ja)
EP (1) EP0584192A1 (ja)
JP (1) JPH0788355B2 (ja)
CN (1) CN1065866A (ja)
AU (1) AU654554B2 (ja)
BR (1) BR9205893A (ja)
CA (1) CA2108557A1 (ja)
CZ (1) CZ390792A3 (ja)
DE (1) DE9290042U1 (ja)
FI (1) FI934566A (ja)
HU (1) HUT65836A (ja)
IE (1) IE921215A1 (ja)
IL (1) IL101546A0 (ja)
NO (1) NO933723D0 (ja)
NZ (1) NZ242391A (ja)
PT (1) PT100394A (ja)
WO (1) WO1992018502A1 (ja)
YU (1) YU40592A (ja)
ZA (1) ZA922811B (ja)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5594007A (en) * 1991-04-18 1997-01-14 Pfizer Inc. Method for treating spinal cord trauma with phenolic 2-piperidino-1-alkanols
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
NZ284852A (en) * 1994-08-18 1998-06-26 Pfizer 3-(piperidin-1-yl)-chroman-4,7-diol and 1-(4-hydrophenyl)-2-(piperidin-1-yl) alkanol derivatives; medicaments; used as a neuroprotective agent
DK0828513T3 (da) 1995-05-26 2004-04-13 Pfizer Kombinationspræparater til behandling af parkinsonisme, indeholdende selektive NMDA-antagonister
TW450807B (en) * 1995-09-15 2001-08-21 Pfizer Pharmaceutical compositions for treating tinnitus comprising neuroprotective agents
US6011042A (en) * 1997-10-10 2000-01-04 Enzon, Inc. Acyl polymeric derivatives of aromatic hydroxyl-containing compounds
EP1220840A2 (en) 1999-10-15 2002-07-10 Bristol-Myers Squibb Pharma Company Bicyclic and tricyclic amines as modulators of chemokine receptor activity
US6784200B2 (en) 2000-10-13 2004-08-31 Bristol-Myers Squibb Pharma Company Bicyclic and tricyclic amines as modulators of chemokine receptor activity
US6476041B1 (en) 1999-10-29 2002-11-05 Merck & Co., Inc. 1,4 substituted piperidinyl NMDA/NR2B antagonists
JP2003512422A (ja) 1999-10-29 2003-04-02 メルク シャープ エンド ドーム リミテッド ベンズイミダゾールｎｍｄａ／ｎｒ２ｂアンタゴニストを使用する疼痛の治療方法
KR100849839B1 (ko) 2001-02-23 2008-08-01 머크 앤드 캄파니 인코포레이티드 Ｎ-치환된 비-아릴-헤테로사이클릭 ｎｍｄａ/ｎｒ2ｂ 길항제 및 이를 포함하는 약제학적 조성물
EP1390034A4 (en) 2001-04-03 2005-07-13 Merck & Co Inc NMDA / NR2B NONARYL-HETEROCYCLO AMIDYL N-SUBSTITUTE ANTAGONISTS
US8648198B2 (en) 2011-01-19 2014-02-11 Cold Spring Harbor Laboratory Phenylethanolamine-based NMDA receptor antagonists
US11931428B2 (en) 2019-08-23 2024-03-19 Wake Forest University Health Sciences Selective hydrogen sulfide probe and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294804A (en) * 1961-01-27 1966-12-27 Sterling Drug Inc 1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propionoxy-piperidine
FR5733M (ja) * 1966-09-27 1968-01-22
DE3045688A1 (de) * 1980-12-04 1982-07-08 C.H. Boehringer Sohn, 6507 Ingelheim Neue 8-arylalkyl-3-phenyl-3-nortropanole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
US5272160A (en) * 1989-05-17 1993-12-21 Pfizer Inc 2-piperidino-1-alkanol derivatives as antiischemic agents
WO1990014087A1 (en) * 1989-05-17 1990-11-29 Pfizer Inc. 2-piperidino-1-alkanol derivatives as antiischemic agents
HU222726B1 (hu) * 1990-02-06 2003-09-29 Pfizer, Inc., Piperidinszármazékok, eljárás elżállításukra és az ezeket tartalmazó gyógyszerkészítmények
DE69132141T2 (de) * 1990-05-10 2000-09-21 Pfizer Inc., New York Neuroprotective indolone und verwandte derivate

Also Published As

Publication number Publication date
FI934566A0 (fi) 1993-10-15
US5696126A (en) 1997-12-09
FI934566A (fi) 1993-10-15
IL101546A0 (en) 1992-12-30
EP0584192A1 (en) 1994-03-02
NZ242391A (en) 1993-12-23
AU1783992A (en) 1992-11-17
US5455250A (en) 1995-10-03
BR9205893A (pt) 1994-11-08
AU654554B2 (en) 1994-11-10
PT100394A (pt) 1993-06-30
JPH0788355B2 (ja) 1995-09-27
CZ390792A3 (en) 1994-04-13
NO933723L (no) 1993-10-15
YU40592A (sh) 1994-12-28
CA2108557A1 (en) 1992-10-19
WO1992018502A1 (en) 1992-10-29
IE921215A1 (en) 1992-10-21
HU9302928D0 (en) 1993-12-28
HUT65836A (en) 1994-07-28
CN1065866A (zh) 1992-11-04
US5654302A (en) 1997-08-05
ZA922811B (en) 1993-10-18
JPH06501022A (ja) 1994-01-27
DE9290042U1 (de) 1993-12-16

Similar Documents

Publication Publication Date Title
NO911591D0 (no) Fremgangsmaate for fremstilling av sukrose-6-ester.
PT100087A (pt) Novos esteres de esteroides
FI88744B (fi) Foerfarande och anordning foer reglering av bergborrning
NO933723D0 (no) Prodrug-estere av fenoliske 2-piperidino-1-alkanoler
FI920396A (fi) Foerfarande foer reglering av en reaktiv sputteringsprocess och anordning foer utfoerande av foerfarandet
FI923019A (fi) Avloppsventil foer en dieselbraennkraftmaskin och foerfarande foer framstaellning av ventilen
FI925784A (fi) Diaram och tillverkningsfoerfarande av densamma
FI922822A (fi) Lindningsanordning och foerfarande foer lindning av en materialrulle
FI921284A (fi) Framstaellnin av styva skum och komposition anvaendbar daeri
FI934336A (fi) Foerfarande och anordning foer bestaemning av servande kommunikationssystem vid sammankopplad funktion av kommunikationssystem
FI921575A (fi) Foerfarande och anordning foer tillslutning av behaollare
FI913985A (fi) Brandbegraensare och foerfarande foer laosning av tillslutningsorganet av brandbegraensaren
FI923399A (fi) Foerfarande och anordning foer minskande av kvaeveoksidutslaepp av foerbraenningsmotorer
FI922931A (fi) Foerfarande och anordning foer fastgoering av en remsa
FI924549A (fi) Tvaettkomposition och testanordning och -metod foer bestaemning av mikroorganismer foerknipade med tandsjukdomar
FI913816A (fi) Foerfarande och arrangemang foer starning av foerbraenningsmotor
FI914455A (fi) Foerfarande och anordning foer behandling av loesgods
MX9101068A (es) Esteres glicidilicos mesogenicos
FI933198A0 (fi) Flytbaeddsbraennkammare med anordningar foer foerbaettring av foerdelning avbraensle och gaser
FI922026A (fi) Anordning foer sortering och rengoering av pappersmaterial
FI88938B (fi) Foerfarande och anordning foer skaerpning av ytan foer traeslipsmaskinens slipsten
FI920961A (fi) Foerfarande och anordning foer framstaellning av foerbaoge
LV10088A (lv) Jauni fenilsulfonilakrilestera atvasinajumi
FI913357A (fi) Foerfarande och form foer framstaellning av en straengsprutad elektronikmodul
FI923414A (fi) Foerfarande och anordning foer tillverkning av braeder