NO930006L - Fremgangsmaate ved fremstilling av beta-laktamer - Google Patents

Fremgangsmaate ved fremstilling av beta-laktamer

Info

Publication number
NO930006L
NO930006L NO93930006A NO930006A NO930006L NO 930006 L NO930006 L NO 930006L NO 93930006 A NO93930006 A NO 93930006A NO 930006 A NO930006 A NO 930006A NO 930006 L NO930006 L NO 930006L
Authority
NO
Norway
Prior art keywords
beta
procedure
preparation
lactam
lactames
Prior art date
Application number
NO93930006A
Other languages
English (en)
Other versions
NO307710B1 (no
NO930006D0 (no
Inventor
Svend Gunnar Kaasgard
Ulla Veitland
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO930006L publication Critical patent/NO930006L/no
Publication of NO930006D0 publication Critical patent/NO930006D0/no
Publication of NO307710B1 publication Critical patent/NO307710B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO930006A 1990-07-04 1993-01-04 Fremgangsmåte ved fremstilling av <beta>-laktamer NO307710B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90610045 1990-07-04
PCT/DK1991/000188 WO1992001061A1 (en) 1990-07-04 1991-07-03 PROCESS FOR PREPARATION OF β-LACTAMS

Publications (3)

Publication Number Publication Date
NO930006L true NO930006L (no) 1993-01-04
NO930006D0 NO930006D0 (no) 1993-01-04
NO307710B1 NO307710B1 (no) 2000-05-15

Family

ID=8205872

Family Applications (1)

Application Number Title Priority Date Filing Date
NO930006A NO307710B1 (no) 1990-07-04 1993-01-04 Fremgangsmåte ved fremstilling av <beta>-laktamer

Country Status (17)

Country Link
US (1) US5525483A (no)
EP (1) EP0537255B1 (no)
JP (1) JP3115593B2 (no)
KR (1) KR100222606B1 (no)
AT (1) ATE317912T1 (no)
AU (1) AU8208691A (no)
CA (1) CA2086250C (no)
CZ (1) CZ381392A3 (no)
DE (1) DE69133509T2 (no)
ES (1) ES2258260T3 (no)
FI (1) FI925988A (no)
NO (1) NO307710B1 (no)
PT (1) PT98205B (no)
RU (1) RU2136759C1 (no)
SK (1) SK381392A3 (no)
WO (1) WO1992001061A1 (no)
ZA (1) ZA915142B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE618979T1 (de) * 1991-12-19 1995-05-18 Novonordisk As Verbesserte methode zur herstellung von bestimmten -g(b)-lactam-antibiotika.
NZ247464A (en) * 1992-04-24 1994-12-22 Lilly Co Eli Preparation of 2-amino-acetamidocephalosporin derivatives, the 2-acetamido group substituted in the 2-position by a c5-6 cyclic hydrocarbon or a c5-heterocycle
AU6106794A (en) * 1993-02-15 1994-08-29 Gist-Brocades N.V. An improved beta -lactam antibiotic composition
BE1007296A3 (nl) * 1993-07-19 1995-05-09 Dsm Nv Werkwijze voor de bereiding van een beta-lactamderivaat.
JPH0719083U (ja) * 1993-09-20 1995-04-04 株式会社江崎製作所 自動二輪車のヘッドパイプ
AUPM543894A0 (en) * 1994-05-04 1994-05-26 Commonwealth Scientific And Industrial Research Organisation An adjuvant
AU2881595A (en) * 1994-06-10 1996-01-05 Gist-Brocades B.V. Improved acylation method for penicillins and cephalosporins
DE69512917D1 (de) * 1994-07-18 1999-11-25 Dsm Nv Verfahren zur herstellung von beta-lactamen mit dauernd hochkonzentrierten reagenzien
BE1009071A3 (nl) * 1995-02-02 1996-11-05 Dsm Nv Werkwijze voor de bereiding van een beta-lactam antibioticum.
ATE191932T1 (de) * 1995-02-28 2000-05-15 Acs Dobfar Spa Verfahren zur enzymatischen synthese von beta- laktam antibiotika in anwesenheit von einem enzyminhibitor
IT1274658B (it) * 1995-02-28 1997-07-18 Acs Dobfar Spa Procedimento enzimatico migliorato per la produzione di penicilline e cefalosporine
US5916762A (en) * 1995-03-31 1999-06-29 Chemferm V.O.F. Process for the recovery of ampicillin
CN1107070C (zh) * 1995-12-08 2003-04-30 吉斯特·布罗卡迪斯股份有限公司 制备抗生素的方法
TW555855B (en) * 1996-07-26 2003-10-01 Bristol Myers Squibb Co Synthesis of beta-lactam antibacterials using soluble side chain esters and enzyme acylase
NL1006266C2 (nl) * 1997-06-10 1998-12-14 Chemferm Vof Werkwijze voor de bereiding van ampicilline.
NL1007302C2 (nl) * 1997-10-17 1999-04-20 Dsm Nv Werkwijze voor de bereiding van een ß-lactam antibioticum.
NL1010506C2 (nl) * 1998-11-06 2000-05-09 Dsm Nv Werkwijze voor de bereiding van bêta-lactam antibiotica.
EP1394262A1 (en) * 2002-08-30 2004-03-03 Bioferma Murcia, S.A. An enzymatic process for preparing beta-lactams
CN101448842A (zh) 2006-05-19 2009-06-03 帝斯曼知识产权资产管理有限公司 一种用于结晶头孢羟氨苄的方法
ATE511547T1 (de) 2007-03-09 2011-06-15 Dsm Ip Assets Bv Verfahren zur herstellung von beta-lactam- verbindungen
CN103635586A (zh) 2011-06-23 2014-03-12 中化帝斯曼制药有限公司荷兰公司 结晶头孢氧哌唑中间体、其制备方法及其制药用途
ES2729707T3 (es) 2011-06-23 2019-11-05 Centrient Pharmaceuticals Netherlands B V Proceso de preparación de cefalosporinas 3'-tiosustituidas empleando una penicilina G acilasa

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3079305A (en) * 1959-09-24 1963-02-26 Bayer Ag Process for the enzymatic acylation of 6-aminopenicillanic acid
US3152050A (en) * 1962-12-27 1964-10-06 American Home Prod Enzymatic process for preparing penicillins
JPS5417030B2 (no) * 1972-12-06 1979-06-27
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
DE3507403A1 (de) * 1985-03-02 1986-09-04 Hoechst Ag, 6230 Frankfurt Enzymatische semisynthese von ss-lactamantibiotika
EP0339751B1 (en) * 1988-04-26 1996-05-29 Gist-Brocades N.V. Process for the enzymatic preparation of beta-lactams
ES2036149A6 (es) * 1989-12-12 1993-05-01 Consejo Superior Investigacion Procedimiento de sintesis de antibioticos semiestaticos en sistemas termodinamicamente controlados agua-cosolventes organicos miscibles apolares con el empleo de penicilina g acilasa.

Also Published As

Publication number Publication date
AU8208691A (en) 1992-02-04
NO307710B1 (no) 2000-05-15
JPH05507623A (ja) 1993-11-04
DE69133509T2 (de) 2006-08-24
SK381392A3 (en) 1995-11-08
EP0537255B1 (en) 2006-02-15
FI925988A0 (fi) 1992-12-31
FI925988A (fi) 1992-12-31
ZA915142B (en) 1992-05-27
DE69133509D1 (de) 2006-04-20
KR100222606B1 (en) 1999-10-01
CA2086250A1 (en) 1992-01-05
PT98205B (pt) 1998-12-31
ATE317912T1 (de) 2006-03-15
US5525483A (en) 1996-06-11
ES2258260T3 (es) 2006-08-16
NO930006D0 (no) 1993-01-04
JP3115593B2 (ja) 2000-12-11
CZ381392A3 (en) 1993-12-15
EP0537255A1 (en) 1993-04-21
RU2136759C1 (ru) 1999-09-10
WO1992001061A1 (en) 1992-01-23
PT98205A (pt) 1992-05-29
CA2086250C (en) 2001-05-29

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