NO922381L - Stabil integrering av dna i bakteriegenomer - Google Patents

Stabil integrering av dna i bakteriegenomer

Info

Publication number
NO922381L
NO922381L NO92922381A NO922381A NO922381L NO 922381 L NO922381 L NO 922381L NO 92922381 A NO92922381 A NO 92922381A NO 922381 A NO922381 A NO 922381A NO 922381 L NO922381 L NO 922381L
Authority
NO
Norway
Prior art keywords
dna
stable integration
replication
bacterial genomes
origin
Prior art date
Application number
NO92922381A
Other languages
English (en)
Norwegian (no)
Other versions
NO922381D0 (no
Inventor
Steen Troels Joergensen
Per Linaa Joergensen
Boerge Krag Diderichsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8148687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO922381(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO922381D0 publication Critical patent/NO922381D0/no
Publication of NO922381L publication Critical patent/NO922381L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO92922381A 1989-12-18 1992-06-17 Stabil integrering av dna i bakteriegenomer NO922381L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK639689A DK639689D0 (da) 1989-12-18 1989-12-18 Indfoering af dna i celler
PCT/DK1990/000332 WO1991009129A1 (en) 1989-12-18 1990-12-18 Stable integration of dna in bacterial genomes

Publications (2)

Publication Number Publication Date
NO922381D0 NO922381D0 (no) 1992-06-17
NO922381L true NO922381L (no) 1992-08-17

Family

ID=8148687

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922381A NO922381L (no) 1989-12-18 1992-06-17 Stabil integrering av dna i bakteriegenomer

Country Status (11)

Country Link
EP (1) EP0506780B2 (es)
JP (1) JP3162707B2 (es)
AT (1) ATE113077T1 (es)
AU (1) AU643741B2 (es)
CA (1) CA2070676A1 (es)
DE (1) DE69013520T3 (es)
DK (2) DK639689D0 (es)
ES (1) ES2064077T5 (es)
FI (1) FI112502B (es)
NO (1) NO922381L (es)
WO (1) WO1991009129A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2665711B1 (fr) * 1990-08-08 1993-08-13 Centre Nat Rech Scient Integron de corynebacterie, procede de transformation d'une corynebacterie par ledit integron et corynebacterie obtenue.
IL110299A0 (en) 1993-07-15 1994-10-21 Novo Nordisk Entotech Inc Formation of and methods for the production of large bacillus thuringiensis crystals with increased pesticidal activity
AU5001496A (en) * 1995-03-22 1996-10-08 Novo Nordisk A/S Introduction of dna into bacillus strains by conjugation
CA2180202A1 (en) * 1995-06-30 1996-12-31 Mika Moriya Method of amplifying gene using artificial transposon
JP4417550B2 (ja) 1997-12-22 2010-02-17 ノボザイムス アクティーゼルスカブ 糖質酸化酵素およびベーキングにおけるその使用
JP4047545B2 (ja) 1998-06-10 2008-02-13 ノボザイムス アクティーゼルスカブ 新規マンナナーゼ
JP3958884B2 (ja) 1998-09-11 2007-08-15 株式会社林原生物化学研究所 非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
AU6188599A (en) 1998-10-26 2000-05-15 Novozymes A/S Constructing and screening a dna library of interest in filamentous fungal cells
AU2001265835A1 (en) 2000-06-23 2002-01-08 Novozymes A/S Method for stable chromosomal multi-copy integration of genes
WO2002099091A2 (en) 2001-06-06 2002-12-12 Novozymes A/S Endo-beta-1,4-glucanase from bacillus
AU2003214036A1 (en) 2002-04-10 2003-10-27 Novozymes A/S Bacillus licheniformis mutant host cell
EP1995319B1 (en) 2002-04-10 2011-08-31 Novozymes A/S Bacillus licheniformis mutant host cell
AU2003223928A1 (en) * 2002-05-07 2003-11-11 Novozymes A/S Homologous recombination into bacterium for the generation of polynucleotide libraries
WO2004053039A2 (en) 2002-12-11 2004-06-24 Novozymes A/S Detergent composition comprising endo-glucanase
EP1694846B1 (en) 2003-12-10 2014-10-01 Novozymes A/S A cell with improved secretion mediated by mrga protein or homologue
US20080044853A1 (en) 2004-06-21 2008-02-21 Novozymes A/S Stably Maintained Multiple Copies of at Least Two Orf in the Same Orientation
US7820408B2 (en) 2006-11-29 2010-10-26 Novozymes, Inc. Methods of improving the introduction of DNA into bacterial cells
WO2008140615A2 (en) 2006-12-21 2008-11-20 Novozymes, Inc. Modified messenger rna stabilizing sequences for expressing genes in bacterial cells
US20120329090A1 (en) 2009-12-21 2012-12-27 Novozymes A/S Methods for Producing Heterologous Polypeptides in Thiol-Disulfide Oxidoreductase-Deficient Bacterial Mutant Cells
EP3532619A1 (en) 2016-10-25 2019-09-04 Novozymes A/S Flp-mediated genomic integration
EP3655528A1 (en) 2017-07-21 2020-05-27 Basf Se Method of transforming bacterial cells
EP3655422B1 (en) 2017-07-21 2023-03-29 Basf Se Promoter for heterologous expression
CN111511908A (zh) 2017-11-10 2020-08-07 诺维信公司 温度敏感性cas9蛋白
US20210017544A1 (en) 2017-12-22 2021-01-21 Novozymes A/S Counter-Selection by Inhibition of Conditionally Essential Genes
CN113366113A (zh) 2019-01-30 2021-09-07 诺维信公司 同源折叠酶共表达
US20220186177A1 (en) 2019-02-20 2022-06-16 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
CN114127256A (zh) 2019-02-20 2022-03-01 巴斯夫欧洲公司 用确定成分培养基和微量元素补料的芽孢杆菌工业发酵工艺
CN113785056A (zh) 2019-03-08 2021-12-10 诺维信公司 改善蛋白酶表达的手段和方法
EP3969576A1 (en) 2019-05-15 2022-03-23 Novozymes A/S Temperature-sensitive rna-guided endonuclease
US20220298517A1 (en) 2019-06-25 2022-09-22 Novozymes A/S Counter-selection by inhibition of conditionally essential genes
WO2021001297A1 (en) 2019-07-02 2021-01-07 Basf Se Method for preparing a fermentation medium
BR112023001386A2 (pt) 2020-07-28 2023-02-14 Basf Se Método para cultivar uma célula hospedeira de bacillus, e, cultura de células hospedeiras de bacillus
MX2023001272A (es) 2020-07-28 2023-03-03 Basf Se Proceso de fermentacion industrial para bacillus mediante el uso de cambio de temperatura.
WO2022023371A1 (en) 2020-07-28 2022-02-03 Basf Se Industrial fermentation process for bacillus using partial harvest
US20240060110A1 (en) 2020-10-07 2024-02-22 Basf Se Bacillus cell with reduced lipase and/or esterase side activities
WO2022269084A1 (en) 2021-06-24 2022-12-29 Basf Se Improved bacillus host cell with altered rema/remb protein
BR112023027009A2 (pt) 2021-06-24 2024-03-12 Basf Se Célula hospedeira modificada de bacillus licheniformis, e, métodos para produzir um composto de interesse e para aumentar a pureza de um composto de interesse
CN117730090A (zh) 2021-07-13 2024-03-19 诺维信公司 重组角质酶表达
WO2023247514A1 (en) 2022-06-22 2023-12-28 Novozymes A/S Recombinant mannanase expression
WO2024028338A1 (en) 2022-08-02 2024-02-08 Basf Se Stabilized protein production process using bacillus host cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4631257A (en) * 1978-12-26 1986-12-23 Cetus Corporation Stable high copy number plasmids
US4401761A (en) * 1981-01-26 1983-08-30 The Upjohn Company Process for stabilizing plasmids by deletion of DNA

Also Published As

Publication number Publication date
EP0506780B1 (en) 1994-10-19
DE69013520T2 (de) 1995-05-04
FI922812A0 (fi) 1992-06-17
WO1991009129A1 (en) 1991-06-27
EP0506780B2 (en) 2004-01-02
DE69013520T3 (de) 2004-09-23
JP3162707B2 (ja) 2001-05-08
FI922812A (fi) 1992-06-17
DK639689D0 (da) 1989-12-18
CA2070676A1 (en) 1991-06-19
JPH05502162A (ja) 1993-04-22
DK0506780T3 (da) 1995-04-18
ATE113077T1 (de) 1994-11-15
AU643741B2 (en) 1993-11-25
AU7031291A (en) 1991-07-18
DK0506780T4 (da) 2004-04-26
NO922381D0 (no) 1992-06-17
ES2064077T5 (es) 2004-09-01
ES2064077T3 (es) 1995-01-16
DE69013520D1 (de) 1994-11-24
FI112502B (fi) 2003-12-15
EP0506780A1 (en) 1992-10-07

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