NO911368D0 - Fremgangsmaate for fremstilling av 2-substituerte alkyl-3-karboksy-karbapenemer. - Google Patents

Fremgangsmaate for fremstilling av 2-substituerte alkyl-3-karboksy-karbapenemer.

Info

Publication number
NO911368D0
NO911368D0 NO911368A NO911368A NO911368D0 NO 911368 D0 NO911368 D0 NO 911368D0 NO 911368 A NO911368 A NO 911368A NO 911368 A NO911368 A NO 911368A NO 911368 D0 NO911368 D0 NO 911368D0
Authority
NO
Norway
Prior art keywords
carbapeems
carboxy
preparing
procedure
substituted alkyl
Prior art date
Application number
NO911368A
Other languages
English (en)
Other versions
NO178624C (no
NO911368L (no
NO178624B (no
Inventor
Carl B Ziegler Jr
William V Curran
Gregg Feigelson
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO911368D0 publication Critical patent/NO911368D0/no
Publication of NO911368L publication Critical patent/NO911368L/no
Priority to NO950203A priority Critical patent/NO179446C/no
Publication of NO178624B publication Critical patent/NO178624B/no
Publication of NO178624C publication Critical patent/NO178624C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO911368A 1990-04-10 1991-04-09 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-substituerte alkyl-3-karboksy-karbapenemer NO178624C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO950203A NO179446C (no) 1990-04-10 1995-01-19 Fremgangsmåte for fremstilling av propargylazetidion-forbindelser

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/507,271 US5068232A (en) 1990-04-10 1990-04-10 Novel 2-substituted alkyl-3-carboxy carbapenems as antibiotics and a method of producing them

Publications (4)

Publication Number Publication Date
NO911368D0 true NO911368D0 (no) 1991-04-09
NO911368L NO911368L (no) 1991-10-11
NO178624B NO178624B (no) 1996-01-22
NO178624C NO178624C (no) 1996-05-02

Family

ID=24017956

Family Applications (1)

Application Number Title Priority Date Filing Date
NO911368A NO178624C (no) 1990-04-10 1991-04-09 Analogifremgangsmåte for fremstilling av terapeutisk aktive 2-substituerte alkyl-3-karboksy-karbapenemer

Country Status (20)

Country Link
US (3) US5068232A (no)
EP (1) EP0478874A3 (no)
JP (1) JPH04234885A (no)
KR (1) KR0183020B1 (no)
CN (3) CN1034332C (no)
AU (1) AU634876B2 (no)
CA (1) CA2039968A1 (no)
CZ (1) CZ280808B6 (no)
FI (1) FI95256C (no)
HU (1) HU215606B (no)
IE (1) IE910676A1 (no)
IL (1) IL97275A (no)
NO (1) NO178624C (no)
NZ (1) NZ237610A (no)
PH (1) PH27462A (no)
PL (3) PL166336B1 (no)
PT (1) PT97301B (no)
SK (1) SK278900B6 (no)
TW (1) TW229209B (no)
ZA (1) ZA912629B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9104838D0 (en) * 1991-03-07 1991-04-17 Glaxo Spa Heterocyclic compounds
US5189158A (en) * 1991-03-20 1993-02-23 American Cyanamid Company 4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them
US5607928A (en) * 1994-08-05 1997-03-04 Zeneca Limited Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives
EP0695753A1 (en) * 1994-08-05 1996-02-07 Zeneca Limited Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use
DK0939632T3 (da) 1996-02-23 2006-01-30 Lilly Co Eli Non-peptidyl vasopressin V1a antagonister
AU2002230290B2 (en) * 2001-02-16 2008-04-10 Pepscan Systems B.V. Arrays for determining binding of biomolecules
CA2569112C (en) * 2004-06-10 2016-04-12 Fob Synthesis, Inc. Carbapenem antibacterials with gram-negative activity and processes for their preparation
KR20070061895A (ko) * 2004-10-08 2007-06-14 다이닛본 스미토모 세이야꾸 가부시끼가이샤 신규의 항균 약제
CN105906537B (zh) * 2016-04-27 2017-12-15 湖南科技学院 （z）式磺酰基烯酸酯化合物的一锅合成方法
CN105884663B (zh) * 2016-04-27 2017-12-15 湖南科技学院 一种(z)‑磺酰基烯酸酯的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56122379A (en) * 1980-03-03 1981-09-25 Sankyo Co Ltd 1-carba-2-penem-3-carboxylic acid derivative
US4350631A (en) * 1980-12-18 1982-09-21 Merck & Co., Inc. 6- and 4-Substituted-1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylates
CA1179675A (en) * 1981-01-30 1984-12-18 Erwin Gotschi 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives
JPS58103388A (ja) * 1981-12-11 1983-06-20 Sankyo Co Ltd カルバペネム誘導体
EP0171064B1 (en) * 1984-08-06 1995-07-12 Fujisawa Pharmaceutical Co., Ltd. Azetidinone derivative and processes for production thereof
EP0184844A1 (en) * 1984-12-13 1986-06-18 Merck & Co. Inc. 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge
US4882429A (en) * 1986-03-03 1989-11-21 Schering Corporation Stereospecific preparation of (3S,4R,5R)-3-(1-hydroxyethyl)-4-benzoyloxy-azeridinones from L-(-)-theonine
IT1197873B (it) * 1986-10-15 1988-12-21 Erba Farmitalia Procedimento per la preparazione di azetidinoni
US5021565A (en) * 1986-10-16 1991-06-04 Merck & Co., Inc. Novel 2-substituted alkyl carbapenem antibacterials
DE3779856T2 (de) * 1986-10-16 1993-03-25 Merck & Co Inc Antibakterielle, 2-substituierte alkyl-carbapeneme.
JPS63218659A (ja) * 1987-03-06 1988-09-12 Yasumitsu Tamura β−ラクタム化合物およびその製造法
JPH0193586A (ja) * 1987-10-05 1989-04-12 Yasumitsu Tamura カルバベネム化合物およびその製造法
US4960879A (en) * 1988-03-23 1990-10-02 Shionogi & Co., Ltd. Process for carbapenem intermediates
JPH0642853Y2 (ja) * 1988-10-28 1994-11-09 新王子製紙株式会社 プリンター
JPH03120280A (ja) * 1989-10-03 1991-05-22 Shionogi & Co Ltd ハロメチルカルバペネム化合物の製法

Also Published As

Publication number Publication date
CN1056878A (zh) 1991-12-11
AU7424891A (en) 1991-10-17
FI911701A0 (fi) 1991-04-09
NO178624C (no) 1996-05-02
PT97301A (pt) 1992-01-31
NO911368L (no) 1991-10-11
HUT57770A (en) 1991-12-30
CS92991A3 (en) 1992-04-15
CZ280808B6 (cs) 1996-04-17
HU911141D0 (en) 1991-10-28
JPH04234885A (ja) 1992-08-24
HU215606B (hu) 1999-01-28
PL165952B1 (pl) 1995-03-31
CN1034332C (zh) 1997-03-26
US5068232A (en) 1991-11-26
PL289814A1 (en) 1992-08-10
FI95256C (fi) 1996-01-10
IL97275A (en) 1996-01-31
ZA912629B (en) 1992-01-29
PL294071A1 (no) 1993-02-08
CN1108648A (zh) 1995-09-20
CN1034329C (zh) 1997-03-26
AU634876B2 (en) 1993-03-04
FI95256B (fi) 1995-09-29
NO178624B (no) 1996-01-22
US5369102A (en) 1994-11-29
TW229209B (no) 1994-09-01
IL97275A0 (en) 1992-05-25
PL166336B1 (pl) 1995-05-31
PH27462A (en) 1993-07-09
PT97301B (pt) 1998-08-31
KR910018384A (ko) 1991-11-30
CN1037177C (zh) 1998-01-28
FI911701A (fi) 1991-10-11
EP0478874A3 (en) 1993-03-24
IE910676A1 (en) 1991-10-23
CA2039968A1 (en) 1991-10-11
EP0478874A2 (en) 1992-04-08
US5480987A (en) 1996-01-02
KR0183020B1 (ko) 1999-05-01
CN1108649A (zh) 1995-09-20
NZ237610A (en) 1995-02-24
PL165937B1 (pl) 1995-03-31
SK278900B6 (sk) 1998-04-08

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