NO873584D0 - Nye 9-deazaguaniner. - Google Patents

Nye 9-deazaguaniner.

Info

Publication number
NO873584D0
NO873584D0 NO873584A NO873584A NO873584D0 NO 873584 D0 NO873584 D0 NO 873584D0 NO 873584 A NO873584 A NO 873584A NO 873584 A NO873584 A NO 873584A NO 873584 D0 NO873584 D0 NO 873584D0
Authority
NO
Norway
Prior art keywords
cells
deazaguanines
new
derivatives
deoxyguanosine
Prior art date
Application number
NO873584A
Other languages
English (en)
Other versions
NO166485C (no
NO166485B (no
NO873584L (no
Inventor
Catherine Rose Kostlan
Jagadish Chandra Sircar
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO873584D0 publication Critical patent/NO873584D0/no
Publication of NO873584L publication Critical patent/NO873584L/no
Publication of NO166485B publication Critical patent/NO166485B/no
Publication of NO166485C publication Critical patent/NO166485C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
NO87873584A 1986-08-26 1987-08-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4h-pyrrolo(3,3-d)-pyrimidin-4-oner. NO166485C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90048686A 1986-08-26 1986-08-26
US5941987A 1987-06-18 1987-06-18

Publications (4)

Publication Number Publication Date
NO873584D0 true NO873584D0 (no) 1987-08-25
NO873584L NO873584L (no) 1988-02-29
NO166485B NO166485B (no) 1991-04-22
NO166485C NO166485C (no) 1991-07-31

Family

ID=26738724

Family Applications (1)

Application Number Title Priority Date Filing Date
NO87873584A NO166485C (no) 1986-08-26 1987-08-25 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4h-pyrrolo(3,3-d)-pyrimidin-4-oner.

Country Status (16)

Country Link
EP (1) EP0260491B1 (no)
JP (2) JP2595254B2 (no)
KR (2) KR940008421B1 (no)
AT (1) ATE67203T1 (no)
AU (1) AU619724B2 (no)
CA (2) CA1293727C (no)
DE (1) DE3772913D1 (no)
DK (1) DK169705B1 (no)
ES (1) ES2038635T3 (no)
FI (1) FI85856C (no)
GR (1) GR3002697T3 (no)
IE (1) IE60433B1 (no)
NO (1) NO166485C (no)
NZ (1) NZ221463A (no)
PH (1) PH24669A (no)
PT (1) PT85582B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1294960C (en) * 1986-10-24 1992-01-28 Thomas C. Malone 7-deazaguanines as immunomodulators
EP0460116B1 (en) * 1989-02-27 1997-08-27 Biocryst Pharmaceuticals Inc. 9-substituted-8-unsubstituted-9-deazaguanines
HUT61765A (en) * 1989-10-31 1993-03-01 Biocryst Inc Process for producing purine nucleoside phosphorylase inhibitors and pharmaceutical compositions comprising same as active ingredient
US5726311A (en) * 1989-11-29 1998-03-10 Biocryst Pharmaceuticals, Inc. 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo 3,2-d!pyrimidine and pharmaceutical uses and compositions containing the same
WO1995001355A1 (en) * 1993-06-30 1995-01-12 Biocryst Pharmaceuticals, Inc. 9-deazahypoxanthines as pnp inhibitors
US5386031A (en) * 1993-12-15 1995-01-31 Warner-Lambert Company Process for the synthesis of 2-amino-3,5-dihydro-7-substituted-4H-pyrrolo[3,]pyrimidin-4-ones
AU695032B2 (en) * 1994-10-05 1998-08-06 Darwin Discovery Limited Purine and guanine compounds as inhibitors of PNP
FR2728181B1 (fr) * 1994-12-16 1997-01-31 Appryl Snc Composante catalytique pour la polymerisation des olefines, son procede de fabrication, et procede de polymerisation des olefines en presence de ladite composante catalytique
US6395733B1 (en) 1995-06-07 2002-05-28 Pfizer Inc Heterocyclic ring-fused pyrimidine derivatives
MX9709867A (es) * 1995-06-07 1998-03-31 Pfizer Derivados de pirimidina condensados con un anillo heterociclico, composiciones que contienen los mismos, y uso de los mismos.
NZ523970A (en) * 2003-02-04 2005-02-25 Ind Res Ltd Process for preparing inhibitors of nucleoside phoshorylases and nucleosidases
CA2540598C (en) * 2003-10-03 2013-09-24 3M Innovative Properties Company Pyrazolopyridines and analogs thereof
NZ540160A (en) * 2005-05-20 2008-03-28 Einstein Coll Med Inhibitors of nucleoside phosphorylases
GB201417163D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Substituted pyrimidine derivatives useful in the treatment of autoimmune diseases
GB201417165D0 (en) * 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Treatments for Autoimmune Disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164556B (no) * 1986-03-06 1989-04-08 Takeda Chemical Industries Ltd
CA1294960C (en) * 1986-10-24 1992-01-28 Thomas C. Malone 7-deazaguanines as immunomodulators
DE3739366A1 (de) * 1987-04-10 1988-10-27 Boehringer Mannheim Gmbh Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel

Also Published As

Publication number Publication date
AU7741687A (en) 1988-03-03
FI85856B (fi) 1992-02-28
NO166485C (no) 1991-07-31
JPH08311040A (ja) 1996-11-26
PT85582B (pt) 1990-05-31
CA1320203C (en) 1993-07-13
NO166485B (no) 1991-04-22
KR940008421B1 (ko) 1994-09-14
ES2038635T3 (es) 1993-08-01
JP2650644B2 (ja) 1997-09-03
DK169705B1 (da) 1995-01-16
PH24669A (en) 1990-09-07
CA1293727C (en) 1991-12-31
FI873648A (fi) 1988-02-27
IE872070L (en) 1988-02-26
JPS6388185A (ja) 1988-04-19
PT85582A (en) 1987-09-01
DK440287D0 (da) 1987-08-24
EP0260491A1 (en) 1988-03-23
NZ221463A (en) 1990-07-26
GR3002697T3 (en) 1993-01-25
EP0260491B1 (en) 1991-09-11
FI873648A0 (fi) 1987-08-24
KR880002873A (ko) 1988-05-12
ATE67203T1 (de) 1991-09-15
DE3772913D1 (de) 1991-10-17
DK440287A (da) 1988-02-27
AU619724B2 (en) 1992-02-06
NO873584L (no) 1988-02-29
IE60433B1 (en) 1994-07-13
FI85856C (fi) 1992-06-10
KR940008848B1 (ko) 1994-09-28
JP2595254B2 (ja) 1997-04-02

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