NO332260B1 - Preparat omfattende en peroksisom-proliferator aktivert reseptor-(PPAR) aktivator valgt fra et fibrat, et tiazolidindion og et benzokinon valgt fra ubikinon, farmasoytisk preparat omfattende samme samt metode for a fremstille slike, slike preparater for anvendelse i terapi samt anvendelse av slike preparater for behandling av sykdom - Google Patents
Preparat omfattende en peroksisom-proliferator aktivert reseptor-(PPAR) aktivator valgt fra et fibrat, et tiazolidindion og et benzokinon valgt fra ubikinon, farmasoytisk preparat omfattende samme samt metode for a fremstille slike, slike preparater for anvendelse i terapi samt anvendelse av slike preparater for behandling av sykdom Download PDFInfo
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- NO332260B1 NO332260B1 NO20031851A NO20031851A NO332260B1 NO 332260 B1 NO332260 B1 NO 332260B1 NO 20031851 A NO20031851 A NO 20031851A NO 20031851 A NO20031851 A NO 20031851A NO 332260 B1 NO332260 B1 NO 332260B1
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- ubiquinone
- ppar
- activator
- peroxisome proliferator
- preparation according
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- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A—HUMAN NECESSITIES
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- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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AUPR1038A AUPR103800A0 (en) | 2000-10-26 | 2000-10-26 | Compositions for the treatment of endothelial dysfunction |
AUPR3424A AUPR342401A0 (en) | 2001-02-28 | 2001-02-28 | Compositions for the treatment of endothelial dysfunction |
PCT/EP2001/012425 WO2002034259A1 (en) | 2000-10-26 | 2001-10-23 | Combination of fenofibrate and coenzyme q10 for the treatment of endothelial dysfunction |
Publications (3)
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NO20031851D0 NO20031851D0 (no) | 2003-04-24 |
NO20031851L NO20031851L (no) | 2003-06-24 |
NO332260B1 true NO332260B1 (no) | 2012-08-13 |
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NO20031851A NO332260B1 (no) | 2000-10-26 | 2003-04-24 | Preparat omfattende en peroksisom-proliferator aktivert reseptor-(PPAR) aktivator valgt fra et fibrat, et tiazolidindion og et benzokinon valgt fra ubikinon, farmasoytisk preparat omfattende samme samt metode for a fremstille slike, slike preparater for anvendelse i terapi samt anvendelse av slike preparater for behandling av sykdom |
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Country | Link |
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US (1) | US7410983B2 (cs) |
EP (1) | EP1328266B1 (cs) |
JP (1) | JP4236464B2 (cs) |
KR (1) | KR100862129B1 (cs) |
CN (1) | CN1220488C (cs) |
AR (1) | AR035071A1 (cs) |
AT (1) | ATE316787T1 (cs) |
AU (1) | AU2176502A (cs) |
BG (1) | BG65979B1 (cs) |
BR (1) | BR0114701A (cs) |
CA (1) | CA2426625C (cs) |
CY (1) | CY1105007T1 (cs) |
CZ (1) | CZ301282B6 (cs) |
DE (1) | DE60117046T2 (cs) |
DK (1) | DK1328266T3 (cs) |
DZ (1) | DZ3442A1 (cs) |
EE (1) | EE05281B1 (cs) |
ES (1) | ES2257457T3 (cs) |
HK (1) | HK1057340A1 (cs) |
HU (1) | HUP0303566A3 (cs) |
IL (2) | IL155524A0 (cs) |
MA (1) | MA25847A1 (cs) |
MX (1) | MXPA03003733A (cs) |
NO (1) | NO332260B1 (cs) |
PL (1) | PL212952B1 (cs) |
PT (1) | PT1328266E (cs) |
RU (1) | RU2003111175A (cs) |
SK (1) | SK287992B6 (cs) |
TN (1) | TNSN01151A1 (cs) |
WO (1) | WO2002034259A1 (cs) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60219793T2 (de) | 2001-07-11 | 2008-01-24 | Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield | Verfahren zur Behandlung von Cytokin-Vermittelten Erkrankungen |
WO2003075911A1 (en) * | 2002-03-11 | 2003-09-18 | Peter Zahradka | Use of ppar alpha agonists for the treatment of vascular and renal diseases |
US20070225614A1 (en) | 2004-05-26 | 2007-09-27 | Endothelix, Inc. | Method and apparatus for determining vascular health conditions |
FR2845602B1 (fr) * | 2002-10-11 | 2005-07-08 | Servier Lab | Association entre un ligand des recepteurs actives par les proliferateurs de peroxisomes et un agent antioxydant et les compositions pharmaceutiques qui les contiennent |
GB0309154D0 (en) * | 2003-01-14 | 2003-05-28 | Aventis Pharma Inc | Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia |
JP2005104951A (ja) * | 2003-01-17 | 2005-04-21 | Kirin Brewery Co Ltd | 血圧降下用組成物および血管柔軟性改善用組成物並びにこれらの機能が付与された食品 |
FR2868313B1 (fr) * | 2004-03-31 | 2008-08-15 | Servier Lab | Nouvelle association entre un compose heterocyclique et un agent antioxydant et les compositions pharmaceutiques qui les contiennent |
EP1621200A1 (en) * | 2004-07-26 | 2006-02-01 | Fournier Laboratories Ireland Limited | Pharmaceutical combinations containing an inhibitor of platelet aggregation and a fibrate |
MX359292B (es) | 2005-06-01 | 2018-09-24 | Bioelectron Tech Corp | Sustancias terapeuticas activas redox para el tratamiento de enfermedades mitocondriales y otras condiciones y modulacion de biomarcadores de energia. |
EP1785133A1 (en) * | 2005-11-10 | 2007-05-16 | Laboratoires Fournier S.A. | Use of fenofibrate or a derivative thereof for preventing diabetic retinopathy |
CA2635280C (en) | 2006-02-22 | 2017-12-12 | Edison Pharmaceuticals, Inc. | Side chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
WO2007106912A2 (en) * | 2006-03-16 | 2007-09-20 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Peroxisome-proliferator activated receptor-alpha agonists for organ preservation |
US20070225606A1 (en) * | 2006-03-22 | 2007-09-27 | Endothelix, Inc. | Method and apparatus for comprehensive assessment of vascular health |
US20080027330A1 (en) * | 2006-05-15 | 2008-01-31 | Endothelix, Inc. | Risk assessment method for acute cardiovascular events |
US20080081963A1 (en) * | 2006-09-29 | 2008-04-03 | Endothelix, Inc. | Methods and Apparatus for Profiling Cardiovascular Vulnerability to Mental Stress |
KR100989093B1 (ko) | 2008-01-18 | 2010-10-25 | 한화제약주식회사 | 생강나무 가지의 추출물을 포함하는 심혈관계 질환의 예방 및 치료용 조성물 |
LT3827815T (lt) | 2008-09-10 | 2023-10-10 | Ptc Therapeutics, Inc. | Psichologinių raidos sutrikimų gydymas oksidacijos redukcijos atžvilgiu aktyviais vaistais |
EP2391219A4 (en) * | 2009-01-29 | 2013-03-06 | Joshua D Levine | METHOD FOR ADDING VEGETABLE SUBSTANCES / NUTRITIONAL AGGREGATES FOR PHARMACEUTICAL TREATMENT IN A PHARMACOTHERAPEUTIC TREATMENT |
US8973851B2 (en) * | 2009-07-01 | 2015-03-10 | The Procter & Gamble Company | Apparatus and methods for producing charged fluid droplets |
US8772349B2 (en) * | 2010-03-26 | 2014-07-08 | Vivacell Biotechnology Espana, S.L. | Cannabinoid quinone derivatives |
RU2554500C2 (ru) * | 2013-09-20 | 2015-06-27 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) | Способ лечения ишемического инсульта |
US10703701B2 (en) | 2015-12-17 | 2020-07-07 | Ptc Therapeutics, Inc. | Fluoroalkyl, fluoroalkoxy, phenoxy, heteroaryloxy, alkoxy, and amine 1,4-benzoquinone derivatives for treatment of oxidative stress disorders |
WO2019084540A1 (en) | 2017-10-27 | 2019-05-02 | Zeta Biolongevity, Inc. | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING PROTEINURY AND ENDOTHELIAL EROSION |
CN110907407B (zh) * | 2019-12-03 | 2022-02-25 | 东北石油大学 | 一种基于spr的高灵敏度光子准晶体光纤折射率传感器 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5229385A (en) | 1986-01-30 | 1993-07-20 | Takeda Chemical Industries, Ltd. | Quinone derivatives, their production and use |
FR2627696B1 (fr) | 1988-02-26 | 1991-09-13 | Fournier Innovation Synergie | Nouvelle forme galenique du fenofibrate |
FI102273B (fi) | 1989-09-11 | 1998-11-13 | Eisai Co Ltd | Kinonijohdannaiset, niiden valmistaminen ja niiden farmakologinen käyt tö |
FR2730231B1 (fr) * | 1995-02-02 | 1997-04-04 | Fournier Sca Lab | Association de fenofibrate et de vitamine e, utilisation en therapeutique |
US6063407A (en) * | 1995-02-16 | 2000-05-16 | The General Hospital Corporation | Treatment of vascular thrombosis and restenosis with inhaled nitric oxide |
AU1856997A (en) | 1996-02-02 | 1997-08-22 | Merck & Co., Inc. | Method for raising hdl cholesterol levels |
GB9606805D0 (en) | 1996-03-30 | 1996-06-05 | Glaxo Wellcome Inc | Medicaments |
HUP0400931A2 (hu) | 1997-11-28 | 2004-07-28 | Karsanov, Nyikolai Vaszilievics | Hypoxia és ischaemia elleni gyógyszer |
US6423742B1 (en) * | 1999-09-02 | 2002-07-23 | Drake Larson | Compositions for reducing vascular plaque formation and methods of using same |
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2001
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- 2001-10-23 DE DE60117046T patent/DE60117046T2/de not_active Expired - Lifetime
- 2001-10-23 HU HU0303566A patent/HUP0303566A3/hu unknown
- 2001-10-23 MX MXPA03003733A patent/MXPA03003733A/es active IP Right Grant
- 2001-10-23 BR BR0114701-3A patent/BR0114701A/pt not_active Application Discontinuation
- 2001-10-23 WO PCT/EP2001/012425 patent/WO2002034259A1/en active IP Right Grant
- 2001-10-23 US US10/399,639 patent/US7410983B2/en not_active Expired - Fee Related
- 2001-10-23 PT PT01988586T patent/PT1328266E/pt unknown
- 2001-10-23 CZ CZ20031148A patent/CZ301282B6/cs not_active IP Right Cessation
- 2001-10-23 KR KR1020037004793A patent/KR100862129B1/ko not_active IP Right Cessation
- 2001-10-23 CA CA2426625A patent/CA2426625C/en not_active Expired - Fee Related
- 2001-10-23 RU RU2003111175/15A patent/RU2003111175A/ru not_active Application Discontinuation
- 2001-10-23 CN CNB01817972XA patent/CN1220488C/zh not_active Expired - Fee Related
- 2001-10-23 DK DK01988586T patent/DK1328266T3/da active
- 2001-10-23 IL IL15552401A patent/IL155524A0/xx active IP Right Grant
- 2001-10-23 SK SK508-2003A patent/SK287992B6/sk unknown
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- 2001-10-23 JP JP2002537311A patent/JP4236464B2/ja not_active Expired - Fee Related
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- 2001-10-26 AR ARP010105032A patent/AR035071A1/es unknown
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2003
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- 2003-04-24 NO NO20031851A patent/NO332260B1/no not_active IP Right Cessation
- 2003-04-25 BG BG107765A patent/BG65979B1/bg unknown
- 2003-04-25 MA MA27124A patent/MA25847A1/fr unknown
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2004
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