NO332166B1 - Formuleringer av paklitaksel - Google Patents
Formuleringer av paklitaksel Download PDFInfo
- Publication number
- NO332166B1 NO332166B1 NO19996433A NO996433A NO332166B1 NO 332166 B1 NO332166 B1 NO 332166B1 NO 19996433 A NO19996433 A NO 19996433A NO 996433 A NO996433 A NO 996433A NO 332166 B1 NO332166 B1 NO 332166B1
- Authority
- NO
- Norway
- Prior art keywords
- paclitaxel
- formulation
- taxol
- capxol
- nanoparticles
- Prior art date
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Classifications
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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- A61K9/5192—Processes
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Physics & Mathematics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
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- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
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US08/926,155 US6096331A (en) | 1993-02-22 | 1997-09-09 | Methods and compositions useful for administration of chemotherapeutic agents |
PCT/US1998/013272 WO1999000113A1 (en) | 1997-06-27 | 1998-06-26 | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
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NO996433D0 NO996433D0 (no) | 1999-12-23 |
NO996433L NO996433L (no) | 2000-02-14 |
NO332166B1 true NO332166B1 (no) | 2012-07-09 |
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NO19996433A NO332166B1 (no) | 1997-06-27 | 1999-12-23 | Formuleringer av paklitaksel |
NO20120338A NO340319B1 (no) | 1997-06-27 | 2012-03-22 | Sammensetning som omfatter nanopartikler som omfatter taxan for cancerbehandling. |
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NO20120338A NO340319B1 (no) | 1997-06-27 | 2012-03-22 | Sammensetning som omfatter nanopartikler som omfatter taxan for cancerbehandling. |
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US (2) | US20080161382A1 (ja) |
EP (1) | EP1023050B1 (ja) |
JP (2) | JP4865937B2 (ja) |
KR (3) | KR100789008B1 (ja) |
CN (2) | CN100462066C (ja) |
AU (1) | AU8266298A (ja) |
BR (1) | BRPI9810945B8 (ja) |
CA (1) | CA2294981C (ja) |
DK (1) | DK1023050T3 (ja) |
ES (1) | ES2435944T3 (ja) |
HK (1) | HK1030543A1 (ja) |
HU (1) | HU230338B1 (ja) |
IL (2) | IL133672A0 (ja) |
MX (1) | MX337149B (ja) |
NO (2) | NO332166B1 (ja) |
NZ (2) | NZ502500A (ja) |
PT (1) | PT1023050E (ja) |
SG (1) | SG113402A1 (ja) |
WO (1) | WO1999000113A1 (ja) |
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US6537579B1 (en) * | 1993-02-22 | 2003-03-25 | American Bioscience, Inc. | Compositions and methods for administration of pharmacologically active compounds |
US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
US20070117863A1 (en) * | 1993-02-22 | 2007-05-24 | Desai Neil P | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US8137684B2 (en) * | 1996-10-01 | 2012-03-20 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
KR100789008B1 (ko) * | 1997-06-27 | 2007-12-26 | 아브락시스 바이오사이언스 인크. | 신규 약물 제제 |
US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
US7314637B1 (en) | 1999-06-29 | 2008-01-01 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
US6040330A (en) * | 1999-01-08 | 2000-03-21 | Bionumerik Pharmaceuticals, Inc. | Pharmaceutical formulations of taxanes |
CA2371912C (en) * | 1999-05-21 | 2010-02-16 | American Bioscience, Inc. | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof |
GB9920548D0 (en) * | 1999-08-31 | 1999-11-03 | Rhone Poulenc Rorer Sa | Treatment of hepatocellular carcinoma |
EP1267946A4 (en) | 2000-02-28 | 2008-07-02 | Genesegues Inc | SYSTEM AND METHOD FOR ENCAPSULATING NANOCAPSULES |
ITMI20001107A1 (it) * | 2000-05-18 | 2001-11-18 | Acs Dobfar Spa | Metodo per il trattamento di tumori solici mediante microparticelle di albumina incorporanti paclitaxel |
AU2002245181B2 (en) | 2000-12-21 | 2006-06-29 | Nektar Therapeutics | Pulmonary delivery of polyene antifungal agents |
US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
US20050048126A1 (en) | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
KR100426636B1 (ko) * | 2001-05-18 | 2004-04-08 | 한국과학기술연구원 | 주사 가능한 젤 상의 조성물 및 그의 제조방법 |
MXPA04002446A (es) | 2001-09-26 | 2004-07-23 | Baxter Int | Preparacion de nanoparticulas de tamano de submicras mediante dispersion y remocion de la fase liquida o solvente. |
US20060003012A9 (en) * | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
ES2625340T3 (es) | 2001-10-15 | 2017-07-19 | Crititech, Inc. | Composiciones y métodos para la administración de fármacos escasamente solubles en agua y métodos de tratamiento |
ITMI20020681A1 (it) * | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Procedimento per la produzione di nanoparticelle di paclitaxel ed albumina |
ITMI20020680A1 (it) * | 2002-03-29 | 2003-09-29 | Acs Dobfar Spa | Composizione antitumorale migliorata a base di paclitaxel e metodo per il suo ottenimento |
US20030207907A1 (en) * | 2002-05-03 | 2003-11-06 | Iversen Patrick L. | Delivery of microparticle-conjugated drugs for inhibition of stenosis |
ITMI20021392A1 (it) * | 2002-06-25 | 2003-12-29 | Nicox Sa | Forme farmaceutiche per la somministrazione orale di farmaci liquidi a temperatura ambiente dotate di migliore biodisponibilita' |
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