NO328824B1 - Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. - Google Patents

Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. Download PDF

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Publication number
NO328824B1
NO328824B1 NO20001508A NO20001508A NO328824B1 NO 328824 B1 NO328824 B1 NO 328824B1 NO 20001508 A NO20001508 A NO 20001508A NO 20001508 A NO20001508 A NO 20001508A NO 328824 B1 NO328824 B1 NO 328824B1
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Prior art keywords
protein
tat
nef
hiv
derivative
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NO20001508A
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English (en)
Norwegian (no)
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NO20001508L (no
NO20001508D0 (no
Inventor
Claudine Elvire Marie Bruck
Stephane Andre Georges Godart
Martine Marchand
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Glaxosmithkline Biolog Sa
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Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of NO20001508D0 publication Critical patent/NO20001508D0/no
Publication of NO20001508L publication Critical patent/NO20001508L/no
Publication of NO328824B1 publication Critical patent/NO328824B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO20001508A 1997-09-26 2000-03-23 Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert. NO328824B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9720585.0A GB9720585D0 (en) 1997-09-26 1997-09-26 Vaccine
PCT/EP1998/006040 WO1999016884A1 (fr) 1997-09-26 1998-09-17 Proteines de fusion comprenant les proteines tat et/ou nef du vih-1

Publications (3)

Publication Number Publication Date
NO20001508D0 NO20001508D0 (no) 2000-03-23
NO20001508L NO20001508L (no) 2000-05-18
NO328824B1 true NO328824B1 (no) 2010-05-25

Family

ID=10819735

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20001508A NO328824B1 (no) 1997-09-26 2000-03-23 Vaksinesammensetninger som omfatter fusjonsproteiner av HIV-1 NEF-proteiner, fremgangsmate for fremstilling av vaksinesammensetning og protein samt nukleinsyre, proteiner og vert.
NO20076467A NO20076467L (no) 1997-09-26 2007-12-14 Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20076467A NO20076467L (no) 1997-09-26 2007-12-14 Fusjonsproteiner som omfatter HIV-1 Tat- og/eller Nef-proteiner

Country Status (28)

Country Link
EP (1) EP1015596B2 (fr)
JP (2) JP2001518300A (fr)
KR (1) KR100554487B1 (fr)
CN (1) CN1188519C (fr)
AR (2) AR017147A1 (fr)
AT (1) ATE338128T1 (fr)
AU (1) AU746564B2 (fr)
BR (1) BR9812547A (fr)
CA (1) CA2305013C (fr)
CO (1) CO4810339A1 (fr)
CZ (1) CZ302878B6 (fr)
DE (1) DE69835756T3 (fr)
DK (1) DK1015596T4 (fr)
ES (1) ES2272012T5 (fr)
GB (1) GB9720585D0 (fr)
HK (1) HK1030431A1 (fr)
HU (1) HUP0004896A3 (fr)
IL (1) IL135102A0 (fr)
NO (2) NO328824B1 (fr)
NZ (1) NZ503482A (fr)
PL (1) PL195243B1 (fr)
PT (1) PT1015596E (fr)
SA (1) SA98190877B1 (fr)
SI (1) SI1015596T2 (fr)
TR (1) TR200000864T2 (fr)
TW (1) TW499436B (fr)
WO (1) WO1999016884A1 (fr)
ZA (1) ZA988789B (fr)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9706957D0 (en) 1997-04-05 1997-05-21 Smithkline Beecham Plc Formulation
GB9720585D0 (en) * 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine
GB9820525D0 (en) * 1998-09-21 1998-11-11 Allergy Therapeutics Ltd Formulation
AU3158900A (en) * 1999-02-25 2000-09-14 Smithkline Beecham Biologicals (Sa) Immunogens comprising a peptide and a carrier derived from h.influenzae protein
DE60031260T2 (de) * 1999-04-12 2007-05-03 Heart Biosystems Gmbh Vorübergehend-immortalisierte zellen zur verwendung in gentherapie
EP1198249B1 (fr) * 1999-06-29 2005-10-19 GlaxoSmithKline Biologicals S.A. Utilisation de cpg comme adjuvant de vaccin contre le vih
GB0000891D0 (en) 2000-01-14 2000-03-08 Allergy Therapeutics Ltd Formulation
EP1251870A2 (fr) * 2000-01-31 2002-10-30 SMITHKLINE BEECHAM BIOLOGICALS s.a. Nouvelle utilisation
US6472176B2 (en) 2000-12-14 2002-10-29 Genvec, Inc. Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof
GB0110431D0 (en) * 2001-04-27 2001-06-20 Glaxosmithkline Biolog Sa Novel compounds
EP1279404A1 (fr) * 2001-07-26 2003-01-29 Istituto Superiore di Sanità Utilisation de HIV-1 tat fragments ou dérivés pour activer des cellules présentatrices d'antigènes, pour délivrer des molécules cargo pour la vaccination ou pour le traitement d'autres maladies
GB0118367D0 (en) * 2001-07-27 2001-09-19 Glaxosmithkline Biolog Sa Novel use
EP1944043A1 (fr) 2001-11-21 2008-07-16 The Trustees of the University of Pennsylvania Séquences d'acides aminés et d'acides nucléiques d'adénovirus simien, vecteurs les contenant, et procédés d'utilisation.
EP3108899A1 (fr) 2001-11-21 2016-12-28 The Trustees of the University of Pennsylvania Séquences d'acide aminé et d'acide nucléique adsv1 adénovirus simien, vecteurs les contenant et procédés d'utilisation
KR100466382B1 (ko) * 2002-01-08 2005-01-14 주식회사 엘지생명과학 인간 면역 결핍 바이러스-1, -2 타입의 단백질이 융합된 재조합 콤보 단백질, 이의 생산방법, 이를 포함하는 벡터, 형질전환된 대장균 및 진단키트
GB0206359D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
PL372092A1 (en) 2002-05-16 2005-07-11 Bavarian Nordic A/S Fusion protein of hiv regulatory/accessory proteins
GB0225788D0 (en) 2002-11-05 2002-12-11 Glaxo Group Ltd Vaccine
WO2005090968A1 (fr) 2004-03-16 2005-09-29 Inist Inc. Compositions immunomoduatrices a base de tat, leur decouverte et leur utilisation
TW200613554A (en) 2004-06-17 2006-05-01 Wyeth Corp Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
GB0417494D0 (en) 2004-08-05 2004-09-08 Glaxosmithkline Biolog Sa Vaccine
GB0507003D0 (en) * 2005-04-06 2005-05-11 Molmed Spa Therapeutic
KR101441843B1 (ko) 2005-10-18 2014-09-17 내셔날 쥬이쉬 헬스 조건부 불멸화 장기 줄기 세포 및 상기 세포의 제조 및 사용 방법
CA2964396A1 (fr) 2007-11-28 2009-06-11 The Trustees Of The University Of Pennsylvania Adenovirus simiens sadv-39, -25.2, -26, -30, -37, et -38 de la sous-famille e et utilisations de ceux-ci
BRPI0819774A2 (pt) 2007-11-28 2014-10-14 Univ Pennsylvania Subfamília c de adenovírus sadv-40, -31 e -34 de símio e seus usos
EP2325298B1 (fr) 2008-03-04 2016-10-05 The Trustees Of The University Of Pennsylvania ADENOVIRUS DE SINGE SAdV-36, -42.1, -42.2, AND -44 ET LEUR UTILISATION
AU2009246876B2 (en) 2008-05-16 2015-04-02 Htyr Acquisition Llc Antibodies and processes for preparing the same
DK2313496T3 (en) 2008-07-21 2014-12-15 Taiga Biotechnologies Inc Anukleære differentiated cells, and method for preparation thereof
AU2009285547B2 (en) 2008-08-28 2012-05-31 Taiga Biotechnologies (Abc), Llc Modulators of MYC, methods of using the same, and methods of identifying agents that modulate MYC
ES2552688T3 (es) 2008-10-31 2015-12-01 The Trustees Of The University Of Pennsylvania Adenovirus de simio con proteínas de la cápside hexónica de SAdV-46 y usos del mismo
US8530431B2 (en) 2009-03-23 2013-09-10 Pin Pharma, Inc. Treatment of cancers with immunostimulatory HIV TAT derivative polypeptides
CN102575232B (zh) 2009-05-29 2015-07-22 宾夕法尼亚大学托管会 猿腺病毒41及其应用
AU2011332025B2 (en) 2010-11-23 2015-06-25 The Trustees Of The University Of Pennsylvania Subfamily E simian adenoviruses A1321, A1325, A1295, A1309 and A1322 and uses thereof
EP2708561A4 (fr) * 2011-03-15 2014-09-24 Univ Yonsei Iacf Bio-aiguille
CN105473723A (zh) 2012-05-18 2016-04-06 宾夕法尼亚大学托管会 亚家族e猿腺病毒a1302、a1320、a1331和a1337及其用途
WO2014012090A1 (fr) * 2012-07-13 2014-01-16 The Broad Institute, Inc. Traîneaux moléculaires comprenant une séquence d'acides aminés à charges positives et cargaison moléculaire et utilisations correspondantes
US9789135B2 (en) 2012-07-20 2017-10-17 Taiga Biotechnologies, Inc. Enhanced reconstitution and autoreconstitution of the hematopoietic compartment
US10272115B2 (en) 2013-03-11 2019-04-30 Taiga Biotechnologies, Inc. Production and use of red blood cells
US9365825B2 (en) 2013-03-11 2016-06-14 Taiga Biotechnologies, Inc. Expansion of adult stem cells in vitro
AU2014329393B2 (en) 2013-10-04 2020-04-30 Pin Pharma, Inc. Immunostimulatory HIV Tat derivative polypeptides for use in cancer treatment
CR20160519A (es) 2014-05-13 2017-01-27 The Trustees Of The Univ Of Pennysylvania Composiciones que comprenden avv que expresa constructos de anticuerpos duales y sus usos
US11207421B2 (en) 2015-04-16 2021-12-28 The Research Foundation For The State University Of New York Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags
AU2016248454B2 (en) * 2015-04-16 2020-05-14 Path Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags
CA3045017A1 (fr) 2016-12-02 2018-06-07 Taiga Biotechnologies, Inc. Formulations de nanoparticules
US10149898B2 (en) 2017-08-03 2018-12-11 Taiga Biotechnologies, Inc. Methods and compositions for the treatment of melanoma
IL308404A (en) 2021-04-27 2024-01-01 Generation Bio Co Non-viral DNA vectors expressing therapeutic antibodies and uses thereof
WO2023177655A1 (fr) 2022-03-14 2023-09-21 Generation Bio Co. Compositions vaccinales prime-boost hétérologues et méthodes d'utilisation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9003010D0 (en) * 1990-02-09 1990-04-04 Glaxo Group Ltd Gene expression in yeast cells
EP0625052A4 (fr) * 1991-10-21 1995-07-19 Medimmune Inc Vecteurs d'expression bacteriens contenant de l'adn codant des signaux de secretion de lipoproteines.
CA2135642C (fr) * 1992-08-21 1999-12-14 James G. Barsoum Polypeptides de transport derives de la proteine tat
ATE302854T1 (de) * 1993-01-26 2005-09-15 Univ Pennsylvania Zusammensetzungen und verfahren zur verabreichung von genetischem material
PL322143A1 (en) * 1995-03-08 1998-01-05 Neovacs Non-topxic immunogenes originating frommretroviral regulator protein, antibodies as such, method of preparing them and pharmaceutic compositions containing them
GB9720585D0 (en) * 1997-09-26 1997-11-26 Smithkline Beecham Biolog Vaccine

Also Published As

Publication number Publication date
JP2001518300A (ja) 2001-10-16
DE69835756T2 (de) 2007-09-13
EP1015596B1 (fr) 2006-08-30
KR100554487B1 (ko) 2006-03-03
DE69835756T3 (de) 2010-09-30
KR20010024287A (ko) 2001-03-26
CN1279718A (zh) 2001-01-10
SI1015596T2 (sl) 2010-07-30
CA2305013A1 (fr) 1999-04-08
SI1015596T1 (sl) 2007-02-28
AU1025599A (en) 1999-04-23
HUP0004896A1 (hu) 2001-04-28
CO4810339A1 (es) 1999-06-30
BR9812547A (pt) 2000-07-25
TR200000864T2 (tr) 2000-08-21
TW499436B (en) 2002-08-21
PL195243B1 (pl) 2007-08-31
ES2272012T3 (es) 2007-04-16
NO20001508L (no) 2000-05-18
DK1015596T4 (da) 2010-07-12
AU746564B2 (en) 2002-05-02
DK1015596T3 (da) 2007-01-02
GB9720585D0 (en) 1997-11-26
DE69835756D1 (de) 2006-10-12
NO20001508D0 (no) 2000-03-23
PT1015596E (pt) 2006-12-29
HK1030431A1 (en) 2001-05-04
HUP0004896A3 (en) 2003-05-28
PL339432A1 (en) 2000-12-18
AR080331A2 (es) 2012-03-28
NZ503482A (en) 2001-09-28
ATE338128T1 (de) 2006-09-15
ZA988789B (en) 2000-03-29
NO20076467L (no) 2000-05-18
JP2009213492A (ja) 2009-09-24
IL135102A0 (en) 2001-05-20
ES2272012T5 (es) 2010-07-06
AR017147A1 (es) 2001-08-22
SA98190877B1 (ar) 2006-09-10
CZ20001091A3 (cs) 2000-09-13
EP1015596B2 (fr) 2010-04-14
CN1188519C (zh) 2005-02-09
CA2305013C (fr) 2008-04-08
WO1999016884A1 (fr) 1999-04-08
CZ302878B6 (cs) 2012-01-04
EP1015596A1 (fr) 2000-07-05

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