NO326245B1 - Anvendelse av et statin for fremstilling av et medikament ved behandling av heterozygot familiaer hyperkolesterolemi - Google Patents
Anvendelse av et statin for fremstilling av et medikament ved behandling av heterozygot familiaer hyperkolesterolemi Download PDFInfo
- Publication number
- NO326245B1 NO326245B1 NO20032292A NO20032292A NO326245B1 NO 326245 B1 NO326245 B1 NO 326245B1 NO 20032292 A NO20032292 A NO 20032292A NO 20032292 A NO20032292 A NO 20032292A NO 326245 B1 NO326245 B1 NO 326245B1
- Authority
- NO
- Norway
- Prior art keywords
- ldl
- treatment
- atorvastatin
- levels
- patients
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title claims description 37
- 239000003814 drug Substances 0.000 title claims description 13
- 238000004519 manufacturing process Methods 0.000 title claims description 3
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title description 13
- 229940079593 drug Drugs 0.000 title description 11
- 208000035150 Hypercholesterolemia Diseases 0.000 title description 5
- 206010045261 Type IIa hyperlipidaemia Diseases 0.000 claims description 32
- 159000000007 calcium salts Chemical class 0.000 claims description 6
- BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 claims description 6
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0028429.9A GB0028429D0 (en) | 2000-11-22 | 2000-11-22 | Therapy |
PCT/GB2001/005041 WO2002041895A1 (en) | 2000-11-22 | 2001-11-16 | Use of rosuvastatin (zd-4522) in the treatment of heterozygous familial hypercholesterolemia |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20032292D0 NO20032292D0 (no) | 2003-05-21 |
NO20032292L NO20032292L (no) | 2003-07-17 |
NO326245B1 true NO326245B1 (no) | 2008-10-27 |
Family
ID=9903629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20032292A NO326245B1 (no) | 2000-11-22 | 2003-05-21 | Anvendelse av et statin for fremstilling av et medikament ved behandling av heterozygot familiaer hyperkolesterolemi |
Country Status (35)
Country | Link |
---|---|
US (1) | US6858618B2 (pt) |
EP (1) | EP1339409B1 (pt) |
JP (2) | JP5062940B2 (pt) |
KR (1) | KR100815042B1 (pt) |
CN (1) | CN1268339C (pt) |
AR (1) | AR031766A1 (pt) |
AT (1) | ATE394103T1 (pt) |
AU (2) | AU1416502A (pt) |
BG (1) | BG66009B1 (pt) |
BR (1) | BR0115511A (pt) |
CA (1) | CA2429263C (pt) |
CY (1) | CY1110428T1 (pt) |
CZ (1) | CZ301583B6 (pt) |
DE (1) | DE60133921D1 (pt) |
DK (1) | DK1339409T3 (pt) |
EE (1) | EE05507B1 (pt) |
ES (1) | ES2305118T3 (pt) |
GB (1) | GB0028429D0 (pt) |
HK (1) | HK1056691A1 (pt) |
HU (1) | HUP0301380A3 (pt) |
IL (2) | IL155919A0 (pt) |
IS (1) | IS6819A (pt) |
MX (1) | MXPA03004336A (pt) |
MY (1) | MY134902A (pt) |
NO (1) | NO326245B1 (pt) |
NZ (1) | NZ525754A (pt) |
PL (1) | PL365386A1 (pt) |
PT (1) | PT1339409E (pt) |
RU (1) | RU2294744C2 (pt) |
SI (1) | SI1339409T1 (pt) |
SK (1) | SK6212003A3 (pt) |
TW (1) | TWI238720B (pt) |
UA (1) | UA75614C2 (pt) |
WO (1) | WO2002041895A1 (pt) |
ZA (1) | ZA200303636B (pt) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0003305D0 (en) * | 2000-02-15 | 2000-04-05 | Zeneca Ltd | Pyrimidine derivatives |
KR20060022647A (ko) * | 2003-04-25 | 2006-03-10 | 길리애드 사이언시즈, 인코포레이티드 | 키나아제 억제 포스포네이트 유사체 |
US7452901B2 (en) * | 2003-04-25 | 2008-11-18 | Gilead Sciences, Inc. | Anti-cancer phosphonate analogs |
WO2004096286A2 (en) | 2003-04-25 | 2004-11-11 | Gilead Sciences, Inc. | Antiviral phosphonate analogs |
US7407965B2 (en) * | 2003-04-25 | 2008-08-05 | Gilead Sciences, Inc. | Phosphonate analogs for treating metabolic diseases |
US7470724B2 (en) * | 2003-04-25 | 2008-12-30 | Gilead Sciences, Inc. | Phosphonate compounds having immuno-modulatory activity |
US20050261237A1 (en) * | 2003-04-25 | 2005-11-24 | Boojamra Constantine G | Nucleoside phosphonate analogs |
US20090247488A1 (en) * | 2003-04-25 | 2009-10-01 | Carina Cannizzaro | Anti-inflammatory phosphonate compounds |
EP1562912A2 (en) * | 2003-08-28 | 2005-08-17 | Teva Pharmaceutical Industries Limited | Process for preparation of rosuvastatin calcium |
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