NO321043B1 - Peptidimmunogene farmasoytiske sammensetninger, en ligand og anvendelse av disse for vaksinasjon og behandling av allergi. - Google Patents

Peptidimmunogene farmasoytiske sammensetninger, en ligand og anvendelse av disse for vaksinasjon og behandling av allergi. Download PDF

Info

Publication number
NO321043B1
NO321043B1 NO19983999A NO983999A NO321043B1 NO 321043 B1 NO321043 B1 NO 321043B1 NO 19983999 A NO19983999 A NO 19983999A NO 983999 A NO983999 A NO 983999A NO 321043 B1 NO321043 B1 NO 321043B1
Authority
NO
Norway
Prior art keywords
bsw17
peptide
ige
mimotope
group
Prior art date
Application number
NO19983999A
Other languages
English (en)
Norwegian (no)
Other versions
NO983999D0 (no
NO983999L (no
Inventor
Franz Kricek
Beda M Stadler
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26308839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO321043(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9604412.8A external-priority patent/GB9604412D0/en
Priority claimed from GBGB9617702.7A external-priority patent/GB9617702D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO983999D0 publication Critical patent/NO983999D0/no
Publication of NO983999L publication Critical patent/NO983999L/no
Publication of NO321043B1 publication Critical patent/NO321043B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/528CH4 domain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19983999A 1996-03-01 1998-08-31 Peptidimmunogene farmasoytiske sammensetninger, en ligand og anvendelse av disse for vaksinasjon og behandling av allergi. NO321043B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9604412.8A GB9604412D0 (en) 1996-03-01 1996-03-01 Organic compounds
GBGB9617702.7A GB9617702D0 (en) 1996-08-22 1996-08-22 Organic compounds
PCT/EP1997/001013 WO1997031948A1 (en) 1996-03-01 1997-02-28 Peptide immunogens for vaccination against and treatment of allergy

Publications (3)

Publication Number Publication Date
NO983999D0 NO983999D0 (no) 1998-08-31
NO983999L NO983999L (no) 1998-11-02
NO321043B1 true NO321043B1 (no) 2006-03-06

Family

ID=26308839

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19983999A NO321043B1 (no) 1996-03-01 1998-08-31 Peptidimmunogene farmasoytiske sammensetninger, en ligand og anvendelse av disse for vaksinasjon og behandling av allergi.

Country Status (24)

Country Link
US (1) US6610297B1 (cs)
EP (1) EP0885244B2 (cs)
JP (2) JP3421970B2 (cs)
KR (2) KR100498198B1 (cs)
CN (1) CN1174998C (cs)
AT (1) ATE230417T1 (cs)
AU (1) AU719609B2 (cs)
BR (1) BR9707819A (cs)
CA (1) CA2245497C (cs)
CY (1) CY2457B1 (cs)
CZ (1) CZ299551B6 (cs)
DE (1) DE69718150T3 (cs)
DK (1) DK0885244T4 (cs)
ES (1) ES2190799T5 (cs)
HU (1) HUP9901109A3 (cs)
IL (1) IL125590A (cs)
NO (1) NO321043B1 (cs)
NZ (1) NZ331651A (cs)
PL (1) PL187209B1 (cs)
RU (1) RU2193413C2 (cs)
SI (1) SI0885244T2 (cs)
SK (1) SK284856B6 (cs)
TR (1) TR199801722T2 (cs)
WO (1) WO1997031948A1 (cs)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621209A3 (en) * 1998-11-02 2006-04-19 Resistentia Pharmaceuticals AB Vaccines based on domains of chimeric immunoglobulin E peptides
US6913749B2 (en) 1998-11-02 2005-07-05 Resistentia Pharmaceuticals Ab Immunogenic polypeptides for inducing anti-self IgE responses
DK1135162T3 (da) 1998-11-30 2009-01-19 Cytos Biotechnology Ag Ordnet molekylær præsentation af allergener, fremstillingsfremgangsmåde samt anvendelse
KR20020007314A (ko) * 1999-02-25 2002-01-26 장 스테판느 Ige의 c-엡실론-3 또는 c-엡실론-4 도메인으로부터유도된 에피토프 또는 미모토프, 이들의 길항제 및 이들의치료학적 용도
CA2363118A1 (en) * 1999-02-25 2000-08-31 Smithkline Beecham Biologicals S.A. Immunogens comprising a peptide and a carrier derived from h.influenzae protein d
GB9908533D0 (en) * 1999-04-14 1999-06-09 Novartis Ag Organic compounds
AU2001252262B2 (en) * 2000-04-13 2006-02-02 Biolife Science Forschungs-und Entwicklungsgesellschaft m.b.H Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells
WO2001085208A2 (en) 2000-05-05 2001-11-15 Cytos Biotechnology Ag Molecular antigen arrays and vaccines
EP1195161A3 (en) 2000-08-30 2002-07-24 Pfizer Products Inc. Anti-IgE vaccines
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
ES2394293T3 (es) * 2001-02-28 2013-01-30 Bio Life Science Forschungs- Und Entwicklungsges.M.B.H. Vacuna contra cánceres que están asociados con el oncogén HER-2/neu
EP1239032A1 (en) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Lactic acid bacteria as agents for treating and preventing allergy
JP2003047482A (ja) 2001-05-22 2003-02-18 Pfizer Prod Inc 非アナフィラキシー誘発性IgEワクチン
AU2002326751A1 (en) 2001-08-13 2003-03-03 Ige Therapeutics, Inc. Immunoglobulin e vaccines and methods of use thereof
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
CA2473416A1 (en) * 2002-01-15 2003-07-24 Erika Jensen-Jarolim Oral vaccination
MXPA05000277A (es) 2002-07-17 2005-03-31 Cytos Biotechnology Ag Configuraciones de antigenos moleculares de usan una particula tipo virus derivada de la proteina de recurimiento ap205.
NZ537003A (en) 2002-07-18 2008-03-28 Cytos Biotechnology Ag Hapten-carrier conjugates comprising virus like particles and uses thereof
PL217409B1 (pl) 2002-07-19 2014-07-31 Cytos Biotechnology Ag Kompozycja, kompozycja farmaceutyczna i kompozycje szczepionki zawierające układ antygenowy amyloidu beta 1-6 oraz sposób ich wytwarzania i zastosowanie
EP2371389A3 (en) 2002-08-14 2012-04-18 MacroGenics, Inc. FcgammaRIIB-specific antibodies and methods of use thereof
US20050065136A1 (en) * 2003-08-13 2005-03-24 Roby Russell R. Methods and compositions for the treatment of infertility using dilute hormone solutions
US20050239757A1 (en) * 2004-04-21 2005-10-27 Roby Russell R Hormone treatment of macular degeneration
US20060025390A1 (en) * 2004-07-28 2006-02-02 Roby Russell R Treatment of hormone allergy and related symptoms and disorders
ES2286558T5 (es) * 2004-08-24 2013-10-15 N.V. Nutricia Composición nutritiva que comprende transgalactooligosacáridos indigeribles y sacáridos de galactosa digeribles
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
DK2029173T3 (en) 2006-06-26 2016-11-07 Macrogenics Inc FC-RIIB-specific antibodies and methods of use thereof
RU2340348C1 (ru) * 2007-04-04 2008-12-10 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Способ лечения атопического дерматита
EP2012122A1 (en) * 2007-07-06 2009-01-07 Medigene AG Mutated parvovirus structural proteins as vaccines
US8865179B2 (en) * 2008-01-26 2014-10-21 Swey-Shen Alexchen Aptameric IgE peptides in a protein scaffold as an allergy vaccine
PE20110891A1 (es) 2008-12-09 2011-12-23 Pfizer Vaccines Llc Vacuna de peptido ch3 de ige
EP2942061A3 (en) 2010-06-07 2016-01-13 Pfizer Vaccines LLC Ige ch3 peptide vaccine
RU2761431C9 (ru) * 2020-10-26 2022-04-18 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171299A (en) 1975-04-04 1979-10-16 The Regents Of The University Of California Polypeptide agents for blocking the human allergic response
DE2602443A1 (de) 1975-04-04 1976-10-21 Univ California Biologisch aktive polypeptide
EP0000252B1 (en) 1977-06-29 1982-02-03 Beecham Group Plc Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides
JPS5944399A (ja) 1982-09-07 1984-03-12 Takeda Chem Ind Ltd 新規dna
GB8616166D0 (en) * 1986-07-02 1986-08-06 Research Corp Ltd Polypeptide competitor
US4892827A (en) 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
EP0269455A3 (en) 1986-11-28 1989-09-06 Takeda Chemical Industries, Ltd. Highly purified fused protein comprising human ige fc fragment and production thereof
WO1988006040A1 (en) 1987-02-20 1988-08-25 Imclone Systems, Inc. Monoclonal antibodies in vaccine formulations
CA1336818C (en) 1987-04-16 1995-08-29 International Institute Of Cellular And Molecular Pathology Treatment of allergy and composition thereof
KR890701761A (ko) 1987-10-13 1989-12-21 제롤드 엘.글릭 면역 진단시약의 제조방법
GB8727045D0 (en) 1987-11-19 1987-12-23 Research Corp Ltd Immunoglobulin e competitor
US5342924A (en) 1987-12-31 1994-08-30 Tanox Biosystems, Inc. Extracellular segments of human ε immunoglobulin anchoring peptides and antibodies specific therefor
US5449760A (en) 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
GB8910263D0 (en) 1989-05-04 1989-06-21 Ciba Geigy Ag Monoclonal antibodies specific for an immunoglobulin isotype
GB8913737D0 (en) 1989-06-15 1989-08-02 Univ Birmingham A novel anti-allergy treatment
DK0512064T3 (da) 1990-01-23 1997-12-15 Tanox Biosystems Inc Ekstracellulære segmenter af human IgE immuno-globulinforankringspeptider og for disse specifikke antistoffer
EP0605410B1 (en) 1990-05-25 1995-08-16 Peptide Therapeutics Limited Immunodiagnostic assay for rheumatoid arthritis
US5258289A (en) 1990-09-05 1993-11-02 Davis Claude G Method for the selecting of genes encoding catalytic antibodies
GB9101550D0 (en) 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
DK0602126T3 (da) * 1991-08-14 2003-06-16 Genentech Inc Immunoglobulinvarianter til specifikke FC epsilon-receptorer
US5965709A (en) * 1991-08-14 1999-10-12 Genentech, Inc. IgE antagonists
SE9102808L (sv) * 1991-09-26 1993-03-27 Lars T Hellman Inst F Immunolo Vaccin, foer humant bruk, vars avsedda effekt aer att lindra symptomen eller foerhindra uppkomsten av ige-medierade allergiska reaktioner
GB9125024D0 (en) 1991-11-25 1992-01-22 Kirby Julian Rheumatoid arthritus treatment
JPH06113881A (ja) 1992-10-07 1994-04-26 Snow Brand Milk Prod Co Ltd ヒト型モノクローナル抗ペプチド抗体及びこれをコードするdna
WO1994025060A1 (en) 1993-04-27 1994-11-10 Ladd Anna E Immunogenic lhrh peptide constructs and synthetic universal immune stimulators for vaccines
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
WO1994026723A2 (en) 1993-05-14 1994-11-24 Genentech, Inc. ras FARNESYL TRANSFERASE INHIBITORS
GB9320897D0 (en) 1993-10-11 1993-12-01 Peptide Therapeutics Ltd Compounds useful in anti-allergy treatment
GB9324013D0 (en) * 1993-11-22 1994-01-12 3I Res Expl Ltd Polypeptides
FR2715304B1 (fr) * 1994-01-26 1996-04-26 Merieux Serums Vaccins Pasteur Vaccin anti-allergique.
CN1146772A (zh) 1994-03-28 1997-04-02 美国联合生物医学公司 用于治疗过敏反应的合成肽免疫原
US5962634A (en) 1994-07-08 1999-10-05 Thomas Jefferson University IgE antagonists
CN1167491A (zh) 1994-10-25 1997-12-10 美国联合生物医学公司 用于治疗变态反应的合成IgE膜锚肽免疫原
WO1998024808A2 (en) 1996-12-06 1998-06-11 THE UNITED STATES OF AMERICA represented by THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH INHIBITION OF IgE-MEDIATED ALLERGIES BY A HUMAN IgE-DERIVED OLIGOPEPTIDE
EP0955311A3 (en) 1998-04-09 2000-08-16 Idexx Laboratories, Inc. Peptide vaccine for canine allergy
TWI229679B (en) 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens

Also Published As

Publication number Publication date
BR9707819A (pt) 1999-07-27
NZ331651A (en) 2000-01-28
DK0885244T4 (da) 2008-06-16
US6610297B1 (en) 2003-08-26
CA2245497C (en) 2009-02-24
AU1879697A (en) 1997-09-16
KR19990087425A (ko) 1999-12-27
DK0885244T3 (da) 2003-04-22
JP2000502571A (ja) 2000-03-07
CN1174998C (zh) 2004-11-10
NO983999D0 (no) 1998-08-31
SK118198A3 (en) 1999-03-12
IL125590A0 (en) 1999-03-12
IL125590A (en) 2001-08-26
HUP9901109A3 (en) 1999-11-29
HK1014962A1 (en) 1999-10-08
ATE230417T1 (de) 2003-01-15
NO983999L (no) 1998-11-02
JP3421970B2 (ja) 2003-06-30
TR199801722T2 (xx) 1998-12-21
ES2190799T3 (es) 2003-08-16
KR100498198B1 (ko) 2005-09-09
CZ299551B6 (cs) 2008-08-27
SI0885244T2 (sl) 2008-10-31
DE69718150T3 (de) 2009-03-05
EP0885244B2 (en) 2008-04-16
CA2245497A1 (en) 1997-09-04
PL187209B1 (pl) 2004-06-30
RU2193413C2 (ru) 2002-11-27
JP2003231696A (ja) 2003-08-19
CZ277198A3 (cs) 1998-12-16
ES2190799T5 (es) 2008-08-16
CY2457B1 (en) 2005-06-03
KR20050049509A (ko) 2005-05-25
HUP9901109A2 (hu) 1999-07-28
SK284856B6 (sk) 2006-01-05
AU719609B2 (en) 2000-05-11
KR100584051B1 (ko) 2006-05-30
CN1213380A (zh) 1999-04-07
PL328858A1 (en) 1999-03-01
DE69718150T2 (de) 2003-08-21
EP0885244B1 (en) 2003-01-02
DE69718150D1 (de) 2003-02-06
EP0885244A1 (en) 1998-12-23
SI0885244T1 (en) 2003-06-30
WO1997031948A1 (en) 1997-09-04

Similar Documents

Publication Publication Date Title
EP0885244B1 (en) Peptide immunogens for vaccination against and treatment of allergy
KR0181313B1 (ko) 면역활성 펜티드 및 항체와 이것들의 항-알레르기 치료에의 이용
CZ20013081A3 (cs) Epitopy a mimotopy získané z oblastí C-epsilon-2 nebo C-epsilon-4 IgE, jejich antagonisté a jejich terapeutické pouľití
CA1256795A (en) Anti-idiotype antibodies induced by synthetic polypeptides
WO2000050460A1 (en) Epitopes or mimotopes derived from the c-epsilon-2 domain of ige, antagonists thereof, and their therapeutic uses
US20030170229A1 (en) Vaccine
US20030147906A1 (en) Epitopes or mimotopes derived from the C-epsilon-3 or C-epsilon-4 domains of lgE, antagonists thereof, and their therapeutic uses
HK1014962B (en) Peptide immunogens for vaccination against and treatment of allergy
US5955076A (en) Immunoactive peptides and antibodies and their use in anti-allergy treatment
US20050214285A1 (en) Epitopes or mimotopes derived from the C-epsilon-3 or C-epsilon-4 domains of IgE, antagonists thereof, and their therapeutic uses
ZA200107016B (en) Epitopes or mimotopes derived from the C-epsilon-2 domain of ige, antagonists thereof, and their therapeutic uses.