NO318598B1 - Anvendelse av nitrogenoksiddonorer eller nitrogenoksidinhibitorer for regulering av cervixdilatasjon og -utvidelsesevne - Google Patents
Anvendelse av nitrogenoksiddonorer eller nitrogenoksidinhibitorer for regulering av cervixdilatasjon og -utvidelsesevne Download PDFInfo
- Publication number
- NO318598B1 NO318598B1 NO19974204A NO974204A NO318598B1 NO 318598 B1 NO318598 B1 NO 318598B1 NO 19974204 A NO19974204 A NO 19974204A NO 974204 A NO974204 A NO 974204A NO 318598 B1 NO318598 B1 NO 318598B1
- Authority
- NO
- Norway
- Prior art keywords
- nitric oxide
- use according
- arginine
- induction
- lip
- Prior art date
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- 229920000647 polyepoxide Polymers 0.000 description 1
- 201000011461 pre-eclampsia Diseases 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 150000003180 prostaglandins Chemical class 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 230000004648 relaxation of smooth muscle Effects 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 210000002460 smooth muscle Anatomy 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 235000010339 sodium tetraborate Nutrition 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 239000000021 stimulant Substances 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 229960003400 sulprostone Drugs 0.000 description 1
- UQZVCDCIMBLVNR-TWYODKAFSA-N sulprostone Chemical compound O[C@@H]1CC(=O)[C@H](C\C=C/CCCC(=O)NS(=O)(=O)C)[C@H]1\C=C\[C@@H](O)COC1=CC=CC=C1 UQZVCDCIMBLVNR-TWYODKAFSA-N 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000005062 synaptic transmission Effects 0.000 description 1
- 238000007910 systemic administration Methods 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229950003937 tolonium Drugs 0.000 description 1
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- BSVBQGMMJUBVOD-UHFFFAOYSA-N trisodium borate Chemical compound [Na+].[Na+].[Na+].[O-]B([O-])[O-] BSVBQGMMJUBVOD-UHFFFAOYSA-N 0.000 description 1
- 210000001215 vagina Anatomy 0.000 description 1
- 229940044950 vaginal gel Drugs 0.000 description 1
- 239000000029 vaginal gel Substances 0.000 description 1
- 229940044977 vaginal tablet Drugs 0.000 description 1
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- 230000002792 vascular Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/04—Nitro compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/223—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of alpha-aminoacids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95250059 | 1995-03-14 | ||
| PCT/US1996/003540 WO1996028145A1 (en) | 1995-03-14 | 1996-03-14 | Use of nitric oxide donors or nitric oxide inhibitors for regulating cervical dilatation and extensibility |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO974204D0 NO974204D0 (no) | 1997-09-12 |
| NO974204L NO974204L (no) | 1997-11-13 |
| NO318598B1 true NO318598B1 (no) | 2005-04-18 |
Family
ID=8221039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19974204A NO318598B1 (no) | 1995-03-14 | 1997-09-12 | Anvendelse av nitrogenoksiddonorer eller nitrogenoksidinhibitorer for regulering av cervixdilatasjon og -utvidelsesevne |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6333350B1 (is) |
| EP (1) | EP0814785B1 (is) |
| JP (1) | JP4579349B2 (is) |
| KR (2) | KR100434238B1 (is) |
| CN (1) | CN1151781C (is) |
| AT (1) | ATE377417T1 (is) |
| AU (1) | AU713172B2 (is) |
| CA (1) | CA2214779A1 (is) |
| CZ (1) | CZ292395B6 (is) |
| DE (1) | DE69637313T2 (is) |
| ES (1) | ES2297838T3 (is) |
| HU (1) | HUP9800826A3 (is) |
| ID (1) | ID20742A (is) |
| IL (1) | IL117496A (is) |
| IS (1) | IS4555A (is) |
| MX (1) | MX9707007A (is) |
| MY (1) | MY116500A (is) |
| NO (1) | NO318598B1 (is) |
| NZ (1) | NZ305169A (is) |
| PL (1) | PL183461B1 (is) |
| RU (1) | RU2199346C2 (is) |
| SK (1) | SK124197A3 (is) |
| TW (1) | TW421594B (is) |
| UA (1) | UA57703C2 (is) |
| WO (1) | WO1996028145A1 (is) |
| ZA (1) | ZA962089B (is) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK124197A3 (en) | 1995-03-14 | 1998-06-03 | Schering Ag | Use of nitric oxide donors or nitric oxide inhibitors for regulating cervical dilatation and extensibility |
| EP0889724A1 (en) * | 1996-02-27 | 1999-01-13 | Rpms Technology Limited | Cox-2 selective inhibitors for managing labour and uterine contractions |
| US6232434B1 (en) | 1996-08-02 | 2001-05-15 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| DE19809845A1 (de) | 1998-03-03 | 1999-09-09 | Jenapharm Gmbh | S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
| ITMI20002117A1 (it) * | 2000-09-29 | 2002-03-29 | Ibsa Inst Biochimique Sa | Uso di sodio nitroprussiato in ostetricia e ginecologia |
| WO2005023189A2 (en) * | 2003-09-03 | 2005-03-17 | Pharmacia Corporation | Method of cox-2 selective inhibitor and nitric oxide-donating agent |
| WO2006089561A1 (en) * | 2005-02-23 | 2006-08-31 | Abbas Abdelsalam Ghazi | Pharmaceutical compositions containing organic acids useful for softening and ripening uterine cervix. |
| US8828981B2 (en) | 2007-02-06 | 2014-09-09 | George Creasy | Progesterone for the treatment or prevention of spontaneous preterm birth |
| CN102283827A (zh) * | 2008-10-16 | 2011-12-21 | 四川维信医药科技有限责任公司 | 单硝酸异山梨酯的新用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5508045A (en) | 1992-10-09 | 1996-04-16 | The Regents Of The University Of California | Method and agents for control and management of labor during pregnancy |
| NZ276105A (en) * | 1993-11-16 | 2001-04-27 | Schering Ag | Use of nitric oxide synthase substrate and/or nitric oxide donor optionally with other compounds to prevent uterine contraction or a nitric oxide inhibitor to stimulate uterine contraction |
| US5550369A (en) | 1994-02-28 | 1996-08-27 | Electro-Pro, Inc. | Triangulation position detection method and apparatus |
| SK124197A3 (en) | 1995-03-14 | 1998-06-03 | Schering Ag | Use of nitric oxide donors or nitric oxide inhibitors for regulating cervical dilatation and extensibility |
-
1996
- 1996-03-14 SK SK1241-97A patent/SK124197A3/sk unknown
- 1996-03-14 ZA ZA962089A patent/ZA962089B/xx unknown
- 1996-03-14 ID IDP960631A patent/ID20742A/id unknown
- 1996-03-14 HU HU9800826A patent/HUP9800826A3/hu unknown
- 1996-03-14 ES ES96909707T patent/ES2297838T3/es not_active Expired - Lifetime
- 1996-03-14 PL PL96322252A patent/PL183461B1/pl not_active IP Right Cessation
- 1996-03-14 MY MYPI96000945A patent/MY116500A/en unknown
- 1996-03-14 AT AT96909707T patent/ATE377417T1/de not_active IP Right Cessation
- 1996-03-14 KR KR1019970706469A patent/KR100434238B1/ko not_active IP Right Cessation
- 1996-03-14 AU AU53117/96A patent/AU713172B2/en not_active Ceased
- 1996-03-14 WO PCT/US1996/003540 patent/WO1996028145A1/en active IP Right Grant
- 1996-03-14 KR KR10-2003-7009932A patent/KR100434239B1/ko not_active IP Right Cessation
- 1996-03-14 CA CA002214779A patent/CA2214779A1/en not_active Abandoned
- 1996-03-14 EP EP96909707A patent/EP0814785B1/en not_active Expired - Lifetime
- 1996-03-14 NZ NZ305169A patent/NZ305169A/en unknown
- 1996-03-14 DE DE69637313T patent/DE69637313T2/de not_active Expired - Lifetime
- 1996-03-14 CN CNB961934336A patent/CN1151781C/zh not_active Expired - Fee Related
- 1996-03-14 CZ CZ19972851A patent/CZ292395B6/cs not_active IP Right Cessation
- 1996-03-14 UA UA97105013A patent/UA57703C2/uk unknown
- 1996-03-14 RU RU97117084/14A patent/RU2199346C2/ru not_active IP Right Cessation
- 1996-03-14 IL IL11749696A patent/IL117496A/en not_active IP Right Cessation
- 1996-03-14 JP JP52783596A patent/JP4579349B2/ja not_active Expired - Fee Related
- 1996-06-27 TW TW085107778A patent/TW421594B/zh not_active IP Right Cessation
-
1997
- 1997-09-05 IS IS4555A patent/IS4555A/is unknown
- 1997-09-12 MX MX9707007A patent/MX9707007A/es not_active IP Right Cessation
- 1997-09-12 NO NO19974204A patent/NO318598B1/no unknown
-
1999
- 1999-01-25 US US09/236,085 patent/US6333350B1/en not_active Expired - Fee Related
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