NO312463B1 - Pyrimid [4,5-b] indoler og forbindelser - Google Patents

Pyrimid [4,5-b] indoler og forbindelser Download PDF

Info

Publication number
NO312463B1
NO312463B1 NO19993359A NO993359A NO312463B1 NO 312463 B1 NO312463 B1 NO 312463B1 NO 19993359 A NO19993359 A NO 19993359A NO 993359 A NO993359 A NO 993359A NO 312463 B1 NO312463 B1 NO 312463B1
Authority
NO
Norway
Prior art keywords
pyrrolidinyl
pyrimido
acetic acid
indol
indoles
Prior art date
Application number
NO19993359A
Other languages
English (en)
Norwegian (no)
Other versions
NO993359L (no
NO993359D0 (no
Inventor
Gordon L Bundy
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO993359D0 publication Critical patent/NO993359D0/no
Publication of NO993359L publication Critical patent/NO993359L/no
Publication of NO312463B1 publication Critical patent/NO312463B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Cosmetics (AREA)
NO19993359A 1997-01-08 1999-07-07 Pyrimid [4,5-b] indoler og forbindelser NO312463B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3522397P 1997-01-08 1997-01-08
US4374997P 1997-04-09 1997-04-09
PCT/US1997/024300 WO1998042708A2 (en) 1997-01-08 1997-12-19 Pharmaceutically active tricyclic amines

Publications (3)

Publication Number Publication Date
NO993359D0 NO993359D0 (no) 1999-07-07
NO993359L NO993359L (no) 1999-09-07
NO312463B1 true NO312463B1 (no) 2002-05-13

Family

ID=26711898

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993359A NO312463B1 (no) 1997-01-08 1999-07-07 Pyrimid [4,5-b] indoler og forbindelser

Country Status (22)

Country Link
US (1) US5932728A (cs)
EP (1) EP0964865B1 (cs)
JP (1) JP2002511061A (cs)
KR (1) KR20000069940A (cs)
CN (1) CN1128798C (cs)
AT (1) ATE233763T1 (cs)
AU (1) AU723709B2 (cs)
CA (1) CA2275389A1 (cs)
CZ (1) CZ288076B6 (cs)
DE (1) DE69719563T2 (cs)
DK (1) DK0964865T3 (cs)
ES (1) ES2193424T3 (cs)
FI (1) FI991568L (cs)
HU (1) HUP0003692A3 (cs)
NO (1) NO312463B1 (cs)
NZ (1) NZ336659A (cs)
PL (1) PL334451A1 (cs)
PT (1) PT964865E (cs)
RU (1) RU2200737C2 (cs)
SI (1) SI0964865T1 (cs)
SK (1) SK283378B6 (cs)
WO (1) WO1998042708A2 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020147216A1 (en) * 2000-01-31 2002-10-10 Yuhong Zhou Mucin synthesis inhibitors
PT1255544E (pt) 2000-01-31 2007-06-15 Genaera Corp Inibidores da síntese da mucina.
US7345051B2 (en) 2000-01-31 2008-03-18 Genaera Corporation Mucin synthesis inhibitors
WO2003037898A1 (en) * 2001-10-31 2003-05-08 Bayer Healthcare Ag Pyrimido [4,5-b] indole derivatives
AU2003300522A1 (en) * 2002-12-27 2004-07-22 Bayer Healthcare Ag 4-phenyl-pyrimido (4,5-b) indole derivatives
ES2736200T3 (es) * 2009-07-22 2019-12-26 Univ Illinois Inhibidores de HDAC y métodos terapéuticos que utilizan los mismos
CN103562208B (zh) 2011-03-15 2016-08-31 默沙东公司 三环促旋酶抑制剂
AU2013212457B2 (en) 2012-01-27 2017-02-16 Universite De Montreal Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells
CA2987974C (en) 2015-06-05 2021-10-12 Hema-Quebec Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL175347B1 (pl) * 1992-04-03 1998-12-31 Upjohn Co Trójpierścieniowe heterocykliczne aminy aktywne farmaceutycznie
US5502187A (en) * 1992-04-03 1996-03-26 The Upjohn Company Pharmaceutically active bicyclic-heterocyclic amines
US5795986A (en) * 1995-03-02 1998-08-18 Pharmacia & Upjohn Company Pyrimido 4,5-B!indoles

Also Published As

Publication number Publication date
HK1023344A1 (en) 2000-09-08
EP0964865A2 (en) 1999-12-22
US5932728A (en) 1999-08-03
HUP0003692A3 (en) 2002-10-28
CN1128798C (zh) 2003-11-26
CA2275389A1 (en) 1998-10-01
WO1998042708A3 (en) 1998-12-17
SK283378B6 (sk) 2003-06-03
PL334451A1 (en) 2000-02-28
NO993359L (no) 1999-09-07
FI991568A7 (fi) 1999-07-08
CZ288076B6 (cs) 2001-04-11
SK90199A3 (en) 2000-05-16
AU723709B2 (en) 2000-09-07
NZ336659A (en) 2001-01-26
ATE233763T1 (de) 2003-03-15
FI991568L (fi) 1999-07-08
CN1239961A (zh) 1999-12-29
PT964865E (pt) 2003-06-30
RU2200737C2 (ru) 2003-03-20
AU8655498A (en) 1998-10-20
DE69719563D1 (de) 2003-04-10
DK0964865T3 (da) 2003-05-05
JP2002511061A (ja) 2002-04-09
DE69719563T2 (de) 2003-11-27
ES2193424T3 (es) 2003-11-01
WO1998042708A2 (en) 1998-10-01
NO993359D0 (no) 1999-07-07
CZ238899A3 (cs) 1999-10-13
SI0964865T1 (en) 2003-08-31
KR20000069940A (ko) 2000-11-25
EP0964865B1 (en) 2003-03-05
HUP0003692A2 (hu) 2001-04-28

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