NO312366B1 - 3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav - Google Patents

3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav Download PDF

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Publication number
NO312366B1
NO312366B1 NO19991012A NO991012A NO312366B1 NO 312366 B1 NO312366 B1 NO 312366B1 NO 19991012 A NO19991012 A NO 19991012A NO 991012 A NO991012 A NO 991012A NO 312366 B1 NO312366 B1 NO 312366B1
Authority
NO
Norway
Prior art keywords
infection
alkyl
groups
aryl
spp
Prior art date
Application number
NO19991012A
Other languages
English (en)
Norwegian (no)
Other versions
NO991012D0 (no
NO991012L (no
Inventor
Peter Bertinato
Hengmiao Cheng
Kristin M Lundby
Martha L Minich
Subas M Sakya
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO991012D0 publication Critical patent/NO991012D0/no
Publication of NO991012L publication Critical patent/NO991012L/no
Publication of NO312366B1 publication Critical patent/NO312366B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO19991012A 1998-03-03 1999-03-02 3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav NO312366B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7663098P 1998-03-03 1998-03-03

Publications (3)

Publication Number Publication Date
NO991012D0 NO991012D0 (no) 1999-03-02
NO991012L NO991012L (no) 1999-09-06
NO312366B1 true NO312366B1 (no) 2002-04-29

Family

ID=22133253

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19991012A NO312366B1 (no) 1998-03-03 1999-03-02 3,6-ketal- og enoleter-makrolidforbindelser, anvendelse derav samt farmasöytisk preparat og fremgangsmåte for fremstilling derav

Country Status (17)

Country Link
US (1) US6043226A (fr)
EP (1) EP0941998B1 (fr)
JP (1) JP3666788B2 (fr)
CN (1) CN1244532A (fr)
AR (1) AR016715A1 (fr)
AT (1) ATE275151T1 (fr)
AU (1) AU741435B2 (fr)
BR (1) BR9900856A (fr)
CA (1) CA2263203C (fr)
DE (1) DE69919769T2 (fr)
DK (1) DK0941998T3 (fr)
ES (1) ES2226282T3 (fr)
HU (1) HUP9900492A3 (fr)
NO (1) NO312366B1 (fr)
NZ (1) NZ334442A (fr)
PT (1) PT941998E (fr)
ZA (1) ZA991664B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
CA2349338C (fr) * 1998-11-03 2005-12-06 Pfizer Products Inc. Nouveaux antibiotiques macrolide
US6514944B2 (en) * 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) * 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
ES2272273T3 (es) 1999-04-16 2007-05-01 Kosan Biosciences, Inc. Agentes antiinfecciosos macrolidos.
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6451768B1 (en) * 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
WO2000071557A1 (fr) * 1999-05-24 2000-11-30 Pfizer Products Inc. Derives de 13-methyl-erythromycine
EP1146051A3 (fr) * 2000-04-10 2001-10-31 Pfizer Products Inc. Dérivées de l' érythromycine A
CA2428158C (fr) * 2000-11-07 2010-06-29 Morphotek, Inc. Procedes pour isoler de nouveaux agents antimicrobiens a partir de cellules mammiferes hypermutables
US8063021B2 (en) * 2002-01-17 2011-11-22 Kosan Biosciences Incorporated Ketolide anti-infective compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
ITMI20022292A1 (it) * 2002-10-29 2004-04-30 Zambon Spa 9a-azalidi ad attivita' antiinfiammatoria.
US20060141470A1 (en) * 2003-02-14 2006-06-29 Kalayoglu Murat V Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
EP1836211B1 (fr) * 2004-12-21 2010-03-03 Pfizer Products Inc. Macrolides
US7517859B2 (en) * 2005-05-04 2009-04-14 Enanta Pharmaceuticals, Inc. Spirocyclic bicyclolides
US20090118506A1 (en) * 2007-09-17 2009-05-07 In Jong Kim 6,11-bridged biaryl macrolides
CA3079368A1 (fr) * 2017-04-20 2018-10-25 Rising Tide Foundation Derives d'azithromycine contenant un ion phosphonium utilises en tant qu'agents anticancereux
GB201706299D0 (en) * 2017-04-20 2017-06-07 Novintum Biotechnology Gmbh Compounds
WO2018193116A1 (fr) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Dérivés d'azithromycine contenant un ion phosphonium utilisés en tant qu'agents anticancéreux
WO2018193111A1 (fr) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Dérivés d'azithromycine contenant un ion phosphonium utilisés en tant qu'agents anticancéreux
EP3612544B1 (fr) 2017-04-20 2022-11-23 Rising Tide Foundation Dérivés d'azithromycine contenant un ion phosphonium en tant qu'agents anticancéreux
WO2018193126A1 (fr) * 2017-04-20 2018-10-25 Novintum Biotechnology Gmbh Dérivés d'azithromycine contenant un ion phosphonium en tant qu'agents antibactériens
US11197872B2 (en) 2017-04-21 2021-12-14 Lunella Biotech, Inc. Vitamin C and doxycycline: a synthetic lethal combination therapy for eradicating cancer stem cells (CSCs)
EP3612177A4 (fr) 2017-04-21 2021-01-13 Lunella Biotech, Inc. Ciblage de cellules souches cancéreuses hypoxiques (csc) à l'aide de doxycycline : implications pour améliorer une thérapie anti-angiogénique
CA3063450A1 (fr) 2017-05-19 2018-11-22 Lunella Biotech, Inc. Diagnostic compagnon pour inhibiteurs mitochondriaux
KR20200010343A (ko) 2017-05-19 2020-01-30 루넬라 바이오테크 인코포레이티드 안티미토신: 암 줄기 세포를 근절하기 위한 미토콘드리아 생물발생의 표적화 억제제
KR102646172B1 (ko) 2017-06-26 2024-03-13 루넬라 바이오테크 인코포레이티드 미토케토신: 암 세포에서 케톤 대사를 표적화하는 미토콘드리아-기반의 치료제
GB201817083D0 (en) * 2018-10-19 2018-12-05 Novintum Biotechnology Gmbh Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8721165D0 (en) * 1987-09-09 1987-10-14 Beecham Group Plc Chemical compounds
EP0344106A3 (fr) * 1988-05-24 1990-01-31 Ciba-Geigy Ag Colorants bleus de dispersion et mélanges de colorants bleus de dispersion
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
CA2154550A1 (fr) * 1993-01-26 1994-08-04 Yoko Misawa Derives de 5-o-desosaminylerythronolide
AU2340797A (en) * 1996-05-07 1997-11-26 Abbott Laboratories 6-o-substituted erythromycins and method for making them

Also Published As

Publication number Publication date
EP0941998B1 (fr) 2004-09-01
NO991012D0 (no) 1999-03-02
CA2263203A1 (fr) 1999-09-03
DE69919769T2 (de) 2005-01-27
HUP9900492A2 (hu) 1999-09-28
ZA991664B (en) 2000-10-12
JPH11315093A (ja) 1999-11-16
HU9900492D0 (en) 1999-04-28
JP3666788B2 (ja) 2005-06-29
HUP9900492A3 (en) 2001-08-28
CN1244532A (zh) 2000-02-16
NO991012L (no) 1999-09-06
DE69919769D1 (de) 2004-10-07
BR9900856A (pt) 2000-04-25
AU1856299A (en) 1999-09-16
DK0941998T3 (da) 2004-09-20
ES2226282T3 (es) 2005-03-16
ATE275151T1 (de) 2004-09-15
CA2263203C (fr) 2002-09-03
US6043226A (en) 2000-03-28
PT941998E (pt) 2004-12-31
EP0941998A2 (fr) 1999-09-15
AU741435B2 (en) 2001-11-29
AR016715A1 (es) 2001-07-25
NZ334442A (en) 2000-03-27
EP0941998A3 (fr) 1999-10-06

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