NO312246B1 - Gj¶rmutanter med N-glykosyleringsdefekter, fremgangsmåte for fremstilling av gj¶rmutanter, og anvendelse av disse, samtfremgangsmåte for fremstilling av et rekombinant protein - Google Patents
Gj¶rmutanter med N-glykosyleringsdefekter, fremgangsmåte for fremstilling av gj¶rmutanter, og anvendelse av disse, samtfremgangsmåte for fremstilling av et rekombinant protein Download PDFInfo
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- NO312246B1 NO312246B1 NO19932811A NO932811A NO312246B1 NO 312246 B1 NO312246 B1 NO 312246B1 NO 19932811 A NO19932811 A NO 19932811A NO 932811 A NO932811 A NO 932811A NO 312246 B1 NO312246 B1 NO 312246B1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
- C12N1/185—Saccharomyces isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
- C12R2001/85—Saccharomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4226094 | 1992-08-07 | ||
| DE4301932A DE4301932A1 (de) | 1992-08-07 | 1993-01-25 | Hefewirtsstämme mit Defekten in der N-Glycosylierung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO932811D0 NO932811D0 (no) | 1993-08-06 |
| NO932811L NO932811L (no) | 1994-02-08 |
| NO312246B1 true NO312246B1 (no) | 2002-04-15 |
Family
ID=25917284
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19932811A NO312246B1 (no) | 1992-08-07 | 1993-08-06 | Gj¶rmutanter med N-glykosyleringsdefekter, fremgangsmåte for fremstilling av gj¶rmutanter, og anvendelse av disse, samtfremgangsmåte for fremstilling av et rekombinant protein |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US5705616A (xx) |
| EP (1) | EP0582244B1 (xx) |
| JP (2) | JP2675511B2 (xx) |
| KR (1) | KR0140973B1 (xx) |
| AT (1) | ATE207955T1 (xx) |
| AU (1) | AU657230B2 (xx) |
| CA (1) | CA2103522C (xx) |
| DE (2) | DE4301932A1 (xx) |
| FI (1) | FI110006B (xx) |
| IL (1) | IL106589A (xx) |
| NO (1) | NO312246B1 (xx) |
| NZ (1) | NZ248323A (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2750434B1 (fr) * | 1996-06-26 | 1998-08-21 | Applic De Rech Et De Conseils | Produit de stabilisation proteique des vins |
| US6566122B1 (en) | 2000-06-16 | 2003-05-20 | Academia Sinica | Super-secreting saccharomyces cerevisiae strains |
| JP4092194B2 (ja) | 2000-06-30 | 2008-05-28 | フランダース インターユニバーシティ インスティテュート フォア バイオテクノロジー （ヴィーアイビー） | ピキアパストリス（ＰｉｃｈｉａＰａｓｔｏｒｉｓ）におけるタンパク質糖鎖修飾 |
| KR100473658B1 (ko) * | 2002-10-25 | 2005-03-10 | 드림바이오젠 주식회사 | 위치 선택적 수식법에 의한 혼성형 단백질 치료제 개발을 위한 형질전환 효모 시스템 |
| US7507573B2 (en) | 2003-11-14 | 2009-03-24 | Vib, Vzw | Modification of protein glycosylation in methylotrophic yeast |
| CN101313216A (zh) * | 2005-09-22 | 2008-11-26 | 普洛茨股份有限公司 | 酵母突变体中产生的糖基化多肽及其使用方法 |
| KR101460561B1 (ko) * | 2012-11-20 | 2014-11-13 | 한국식품연구원 | 사카로마이세스 세레비지애 113-8의 대량 생산방법 |
| WO2017170418A1 (ja) * | 2016-03-30 | 2017-10-05 | 株式会社カネカ | エンドヌクレアーゼ活性を有するポリペプチド及びその製造方法 |
| CN107988177B (zh) * | 2016-10-26 | 2021-08-20 | 潍坊康地恩生物科技有限公司 | 葡萄糖氧化酶突变体 |
| CN108118037B (zh) * | 2016-11-28 | 2021-08-31 | 青岛蔚蓝生物集团有限公司 | 一种耐热性提高的葡萄糖氧化酶突变体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5135854A (en) * | 1987-10-29 | 1992-08-04 | Zymogenetics, Inc. | Methods of regulating protein glycosylation |
| EP0314096B1 (en) * | 1987-10-29 | 1994-01-12 | Zymogenetics, Inc. | Methods of regulating protein glycosylation |
| NZ229260A (en) * | 1988-06-03 | 1994-02-25 | Merck & Co Inc | Hepatitis b virus, expression cassette for pre-s domain, host cells and |
| US5094951A (en) * | 1988-06-21 | 1992-03-10 | Chiron Corporation | Production of glucose oxidase in recombinant systems |
| EP0382332A3 (en) * | 1989-01-06 | 1990-11-14 | Collaborative Research Inc. | Improved supersecreting mutants of saccharomyces cerevisiae |
| CA2022109A1 (en) * | 1989-07-31 | 1991-02-01 | Cheryl A. Schulman | Enhanced expression of heterologous proteins in recombinant hosts in a non-growth media |
| DE4301904A1 (de) * | 1992-08-07 | 1994-02-10 | Boehringer Mannheim Gmbh | Hypoglycosylierte recombinante Glucoseoxidase |
-
1993
- 1993-01-25 DE DE4301932A patent/DE4301932A1/de not_active Withdrawn
- 1993-08-02 EP EP93112338A patent/EP0582244B1/de not_active Expired - Lifetime
- 1993-08-02 AT AT93112338T patent/ATE207955T1/de not_active IP Right Cessation
- 1993-08-02 DE DE59310233T patent/DE59310233D1/de not_active Expired - Lifetime
- 1993-08-02 AU AU44354/93A patent/AU657230B2/en not_active Ceased
- 1993-08-04 IL IL10658993A patent/IL106589A/xx not_active IP Right Cessation
- 1993-08-04 NZ NZ248323A patent/NZ248323A/en unknown
- 1993-08-06 FI FI933487A patent/FI110006B/fi not_active IP Right Cessation
- 1993-08-06 JP JP5196388A patent/JP2675511B2/ja not_active Expired - Fee Related
- 1993-08-06 CA CA002103522A patent/CA2103522C/en not_active Expired - Lifetime
- 1993-08-06 KR KR1019930015252A patent/KR0140973B1/ko not_active IP Right Cessation
- 1993-08-06 NO NO19932811A patent/NO312246B1/no unknown
-
1995
- 1995-06-05 US US08/461,593 patent/US5705616A/en not_active Expired - Lifetime
-
1996
- 1996-05-31 US US08/651,323 patent/US5798226A/en not_active Expired - Lifetime
-
1997
- 1997-04-09 JP JP9090937A patent/JP2984229B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI933487A (fi) | 1994-02-08 |
| CA2103522A1 (en) | 1994-02-08 |
| DE59310233D1 (de) | 2001-12-06 |
| FI110006B (fi) | 2002-11-15 |
| IL106589A (en) | 2005-07-25 |
| US5798226A (en) | 1998-08-25 |
| ATE207955T1 (de) | 2001-11-15 |
| JP2984229B2 (ja) | 1999-11-29 |
| AU657230B2 (en) | 1995-03-02 |
| KR940004051A (ko) | 1994-03-14 |
| EP0582244B1 (de) | 2001-10-31 |
| NZ248323A (en) | 1994-12-22 |
| DE4301932A1 (de) | 1994-02-10 |
| JP2675511B2 (ja) | 1997-11-12 |
| KR0140973B1 (ko) | 1998-06-15 |
| CA2103522C (en) | 1998-07-07 |
| JPH1052277A (ja) | 1998-02-24 |
| FI933487A0 (fi) | 1993-08-06 |
| NO932811D0 (no) | 1993-08-06 |
| EP0582244A2 (de) | 1994-02-09 |
| IL106589A0 (en) | 1993-12-08 |
| AU4435493A (en) | 1994-02-24 |
| NO932811L (no) | 1994-02-08 |
| JPH06296482A (ja) | 1994-10-25 |
| EP0582244A3 (de) | 1995-03-15 |
| US5705616A (en) | 1998-01-06 |
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