NO311253B1 - Aminhydrofluorider og deres anvendelse som orale hygienepreparater - Google Patents
Aminhydrofluorider og deres anvendelse som orale hygienepreparater Download PDFInfo
- Publication number
- NO311253B1 NO311253B1 NO19992308A NO992308A NO311253B1 NO 311253 B1 NO311253 B1 NO 311253B1 NO 19992308 A NO19992308 A NO 19992308A NO 992308 A NO992308 A NO 992308A NO 311253 B1 NO311253 B1 NO 311253B1
- Authority
- NO
- Norway
- Prior art keywords
- amine
- oral hygiene
- mixture
- hygiene composition
- fluoride
- Prior art date
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- -1 Amine hydrofluorides Chemical class 0.000 title claims description 51
- 238000002360 preparation method Methods 0.000 title claims description 9
- 239000000203 mixture Substances 0.000 claims description 95
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims description 31
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 claims description 25
- 150000001412 amines Chemical class 0.000 claims description 20
- 238000004140 cleaning Methods 0.000 claims description 19
- 239000000606 toothpaste Substances 0.000 claims description 19
- LDDQLRUQCUTJBB-UHFFFAOYSA-N ammonium fluoride Chemical compound [NH4+].[F-] LDDQLRUQCUTJBB-UHFFFAOYSA-N 0.000 claims description 18
- 125000001183 hydrocarbyl group Chemical group 0.000 claims description 15
- 229940034610 toothpaste Drugs 0.000 claims description 14
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 12
- 239000000194 fatty acid Substances 0.000 claims description 12
- 229930195729 fatty acid Natural products 0.000 claims description 12
- 150000004665 fatty acids Chemical class 0.000 claims description 12
- 239000003921 oil Substances 0.000 claims description 11
- 235000019484 Rapeseed oil Nutrition 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 10
- 235000019198 oils Nutrition 0.000 claims description 10
- 235000012424 soybean oil Nutrition 0.000 claims description 10
- 239000003549 soybean oil Substances 0.000 claims description 10
- 229910000040 hydrogen fluoride Inorganic materials 0.000 claims description 9
- 239000003760 tallow Substances 0.000 claims description 9
- 235000015278 beef Nutrition 0.000 claims description 8
- 125000004432 carbon atom Chemical group C* 0.000 claims description 8
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- 235000019737 Animal fat Nutrition 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 5
- ANOBYBYXJXCGBS-UHFFFAOYSA-L stannous fluoride Chemical compound F[Sn]F ANOBYBYXJXCGBS-UHFFFAOYSA-L 0.000 claims description 5
- 229960002799 stannous fluoride Drugs 0.000 claims description 5
- 125000003438 dodecyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 claims description 4
- 125000001421 myristyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
- 125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 4
- 125000004079 stearyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 3
- 125000001204 arachidyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
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- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 244000070406 Malus silvestris Species 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 235000011236 Persea americana var americana Nutrition 0.000 description 1
- 240000002426 Persea americana var. drymifolia Species 0.000 description 1
- 229920003072 Plasdone™ povidone Polymers 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 229920001615 Tragacanth Polymers 0.000 description 1
- 239000000619 acesulfame-K Substances 0.000 description 1
- 229960000583 acetic acid Drugs 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 238000001838 alkalimetric titration Methods 0.000 description 1
- 229910000316 alkaline earth metal phosphate Inorganic materials 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- SNAAJJQQZSMGQD-UHFFFAOYSA-N aluminum magnesium Chemical compound [Mg].[Al] SNAAJJQQZSMGQD-UHFFFAOYSA-N 0.000 description 1
- SMYKVLBUSSNXMV-UHFFFAOYSA-K aluminum;trihydroxide;hydrate Chemical class O.[OH-].[OH-].[OH-].[Al+3] SMYKVLBUSSNXMV-UHFFFAOYSA-K 0.000 description 1
- 150000007854 aminals Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 229940011037 anethole Drugs 0.000 description 1
- 239000010775 animal oil Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 238000013475 authorization Methods 0.000 description 1
- 239000010480 babassu oil Substances 0.000 description 1
- 235000012216 bentonite Nutrition 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 description 1
- 229910052794 bromium Inorganic materials 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 230000001013 cariogenic effect Effects 0.000 description 1
- 239000012876 carrier material Substances 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229920003086 cellulose ether Polymers 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000010500 citrus oil Substances 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 229960000956 coumarin Drugs 0.000 description 1
- 235000001671 coumarin Nutrition 0.000 description 1
- HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical class OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 description 1
- QGSCPWWHMSCFOV-RRABGKBLSA-N dectaflur Chemical compound [F-].CCCCCCCC\C=C\CCCCCCCC[NH3+] QGSCPWWHMSCFOV-RRABGKBLSA-N 0.000 description 1
- 229950010002 dectaflur Drugs 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000007857 degradation product Substances 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000006356 dehydrogenation reaction Methods 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 125000004185 ester group Chemical group 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000007046 ethoxylation reaction Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 229940013317 fish oils Drugs 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- 238000004508 fractional distillation Methods 0.000 description 1
- 238000010575 fractional recrystallization Methods 0.000 description 1
- 235000021588 free fatty acids Nutrition 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- 239000012362 glacial acetic acid Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 239000000416 hydrocolloid Substances 0.000 description 1
- 229910000042 hydrogen bromide Inorganic materials 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 description 1
- 229910000043 hydrogen iodide Inorganic materials 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 235000021388 linseed oil Nutrition 0.000 description 1
- 239000000944 linseed oil Substances 0.000 description 1
- 239000000391 magnesium silicate Substances 0.000 description 1
- 235000012243 magnesium silicates Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- DXYUWQFEDOQSQY-UHFFFAOYSA-N n'-octadecylpropane-1,3-diamine Chemical compound CCCCCCCCCCCCCCCCCCNCCCN DXYUWQFEDOQSQY-UHFFFAOYSA-N 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 230000000269 nucleophilic effect Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- QGSCPWWHMSCFOV-UHFFFAOYSA-N octadec-9-enylazanium;fluoride Chemical compound F.CCCCCCCCC=CCCCCCCCCN QGSCPWWHMSCFOV-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940060184 oil ingredients Drugs 0.000 description 1
- FATBGEAMYMYZAF-KTKRTIGZSA-N oleamide Chemical compound CCCCCCCC\C=C/CCCCCCCC(N)=O FATBGEAMYMYZAF-KTKRTIGZSA-N 0.000 description 1
- 229940113162 oleylamide Drugs 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 239000003346 palm kernel oil Substances 0.000 description 1
- 235000019865 palm kernel oil Nutrition 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- RUVINXPYWBROJD-UHFFFAOYSA-N para-methoxyphenyl Natural products COC1=CC=C(C=CC)C=C1 RUVINXPYWBROJD-UHFFFAOYSA-N 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 229920000768 polyamine Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001451 polypropylene glycol Polymers 0.000 description 1
- 150000004804 polysaccharides Polymers 0.000 description 1
- 235000015277 pork Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 239000008171 pumpkin seed oil Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 238000006722 reduction reaction Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229940100486 rice starch Drugs 0.000 description 1
- 239000012487 rinsing solution Substances 0.000 description 1
- 235000005713 safflower oil Nutrition 0.000 description 1
- 239000003813 safflower oil Substances 0.000 description 1
- 235000003441 saturated fatty acids Nutrition 0.000 description 1
- 150000004671 saturated fatty acids Chemical class 0.000 description 1
- 229930195734 saturated hydrocarbon Natural products 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- YUOWTJMRMWQJDA-UHFFFAOYSA-J tin(iv) fluoride Chemical compound [F-].[F-].[F-].[F-].[Sn+4] YUOWTJMRMWQJDA-UHFFFAOYSA-J 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 239000010698 whale oil Substances 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH284396 | 1996-11-18 | ||
| PCT/CH1997/000435 WO1998022427A1 (de) | 1996-11-18 | 1997-11-17 | Aminhydrofluoride und ihre verwendung als mundpflegemittel |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO992308D0 NO992308D0 (no) | 1999-05-12 |
| NO992308L NO992308L (no) | 1999-05-12 |
| NO311253B1 true NO311253B1 (no) | 2001-11-05 |
Family
ID=4242840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19992308A NO311253B1 (no) | 1996-11-18 | 1999-05-12 | Aminhydrofluorider og deres anvendelse som orale hygienepreparater |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6464962B2 (hu) |
| EP (1) | EP0944579B1 (hu) |
| JP (1) | JP2000511930A (hu) |
| KR (1) | KR20000053338A (hu) |
| AT (1) | ATE207873T1 (hu) |
| AU (1) | AU4860597A (hu) |
| BG (1) | BG103406A (hu) |
| CA (1) | CA2272106C (hu) |
| CZ (1) | CZ165999A3 (hu) |
| DE (1) | DE59705220D1 (hu) |
| DK (1) | DK0944579T3 (hu) |
| EE (1) | EE9900197A (hu) |
| ES (1) | ES2165029T3 (hu) |
| HR (1) | HRP970622A2 (hu) |
| HU (1) | HUP0000377A2 (hu) |
| IL (1) | IL129805A (hu) |
| NO (1) | NO311253B1 (hu) |
| PL (1) | PL333377A1 (hu) |
| PT (1) | PT944579E (hu) |
| SK (1) | SK63099A3 (hu) |
| TR (1) | TR199901089T2 (hu) |
| WO (1) | WO1998022427A1 (hu) |
| YU (1) | YU33199A (hu) |
| ZA (1) | ZA9710381B (hu) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1377901A (en) * | 1999-12-03 | 2001-06-12 | Gaba International Ag | Oral hygiene agents containing amine hydrofluoride |
| EP1129692B1 (de) * | 2000-03-02 | 2004-06-02 | Dr. Scheller Cosmetics AG | Mundspüllösung enthaltend Triclosan und Aminfluorid |
| AU2003218853A1 (en) | 2002-04-25 | 2003-11-10 | Gaba International Ag | Oral care products containing ovomucin |
| US8778889B2 (en) * | 2003-03-10 | 2014-07-15 | The United States Of America As Represented By The Secretary Of The Army | Antimicrobial decapeptide oral hygiene treatment |
| US7494980B2 (en) * | 2003-03-10 | 2009-02-24 | The United States Of America As Represented By The Secretary Of The Army | Antimicrobial peptide and methods of use thereof |
| CN106074197A (zh) * | 2008-04-24 | 2016-11-09 | 加巴国际控股有限公司 | 包含溶解的锡和氟化物的口腔护理组合物 |
| EP2111844A1 (en) | 2008-04-24 | 2009-10-28 | Gaba International AG | Oral care composition comprising dissolved tin and fluoride |
| EP2374446B1 (en) | 2010-04-07 | 2013-03-20 | GABA International Holding AG | Oral care composition comprising stannous and nitrate ions |
| DE102010030546A1 (de) * | 2010-06-25 | 2011-01-05 | Lr Health And Beauty Systems Gmbh | Zahnpflegekaugummi mit Silberanteilen |
| MX352730B (es) * | 2012-12-21 | 2017-12-06 | Gaba Int Holding Ag | Composición para el cuidado oral. |
| JP7290906B2 (ja) * | 2015-02-13 | 2023-06-14 | ロート製薬株式会社 | 歯根膜再生剤及びその製造方法 |
| EP3962444A1 (en) | 2019-04-29 | 2022-03-09 | 3M Innovative Properties Company | Quaternary ammonium alkyl component containing oral care composition for treating caries |
| WO2022133221A1 (en) * | 2020-12-18 | 2022-06-23 | Colgate-Palmolive Company | Oral care compositions with amine flourides |
| CN118515573B (zh) * | 2024-07-19 | 2024-09-27 | 浙江省产品质量安全科学研究院 | 一种稳定同位素标记的氘代奥拉氟化合物的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA548096A (en) | 1951-08-26 | 1957-10-29 | Eichler Oskar | Dentifrice containing reactive fluorine and a method of making same |
| BE569397A (hu) * | 1957-07-13 | |||
| GB1056962A (en) * | 1964-10-30 | 1967-02-01 | Grace W R & Co | Improvements in forming cold water dispersions of aliphatic fatty amines |
| US3472900A (en) | 1966-07-18 | 1969-10-14 | Baird Chem Ind | Preparation of trialkylamines |
| US3983175A (en) | 1972-11-17 | 1976-09-28 | Kuraray Co., Ltd. | Process for the production of a substituted ketone |
| US4122162A (en) * | 1974-05-31 | 1978-10-24 | Muehlemann Hans R | Oral composition for plaque and caries inhibition |
| US4160022A (en) | 1975-09-15 | 1979-07-03 | Colgate Palmolive Company | Toothpaste |
| US5665333A (en) * | 1995-01-17 | 1997-09-09 | Homola; Andrew M. | Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth |
-
1997
- 1997-11-17 JP JP10523043A patent/JP2000511930A/ja active Pending
- 1997-11-17 IL IL12980597A patent/IL129805A/en not_active IP Right Cessation
- 1997-11-17 AT AT97911101T patent/ATE207873T1/de active
- 1997-11-17 KR KR1019990704358A patent/KR20000053338A/ko not_active Application Discontinuation
- 1997-11-17 HR HR2843/96A patent/HRP970622A2/hr not_active Application Discontinuation
- 1997-11-17 CZ CZ991659A patent/CZ165999A3/cs unknown
- 1997-11-17 WO PCT/CH1997/000435 patent/WO1998022427A1/de not_active Application Discontinuation
- 1997-11-17 EE EEP199900197A patent/EE9900197A/xx unknown
- 1997-11-17 YU YU33199A patent/YU33199A/sh unknown
- 1997-11-17 DK DK97911101T patent/DK0944579T3/da active
- 1997-11-17 US US09/308,380 patent/US6464962B2/en not_active Expired - Lifetime
- 1997-11-17 HU HU0000377A patent/HUP0000377A2/hu unknown
- 1997-11-17 SK SK630-99A patent/SK63099A3/sk unknown
- 1997-11-17 CA CA002272106A patent/CA2272106C/en not_active Expired - Lifetime
- 1997-11-17 ES ES97911101T patent/ES2165029T3/es not_active Expired - Lifetime
- 1997-11-17 DE DE59705220T patent/DE59705220D1/de not_active Expired - Lifetime
- 1997-11-17 AU AU48605/97A patent/AU4860597A/en not_active Abandoned
- 1997-11-17 PL PL97333377A patent/PL333377A1/xx unknown
- 1997-11-17 PT PT97911101T patent/PT944579E/pt unknown
- 1997-11-17 EP EP97911101A patent/EP0944579B1/de not_active Expired - Lifetime
- 1997-11-17 TR TR1999/01089T patent/TR199901089T2/xx unknown
- 1997-11-18 ZA ZA9710381A patent/ZA9710381B/xx unknown
-
1999
- 1999-05-12 NO NO19992308A patent/NO311253B1/no not_active IP Right Cessation
- 1999-05-17 BG BG103406A patent/BG103406A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA9710381B (en) | 1998-06-10 |
| HRP970622A2 (en) | 1998-08-31 |
| HUP0000377A2 (hu) | 2000-06-28 |
| JP2000511930A (ja) | 2000-09-12 |
| PT944579E (pt) | 2002-03-28 |
| TR199901089T2 (xx) | 1999-09-21 |
| NO992308D0 (no) | 1999-05-12 |
| US20010006622A1 (en) | 2001-07-05 |
| CA2272106A1 (en) | 1998-05-28 |
| KR20000053338A (ko) | 2000-08-25 |
| EP0944579B1 (de) | 2001-10-31 |
| PL333377A1 (en) | 1999-12-06 |
| DK0944579T3 (da) | 2002-01-07 |
| CA2272106C (en) | 2003-11-04 |
| NO992308L (no) | 1999-05-12 |
| EP0944579A1 (de) | 1999-09-29 |
| WO1998022427A1 (de) | 1998-05-28 |
| EE9900197A (et) | 1999-12-15 |
| CZ165999A3 (cs) | 1999-11-17 |
| DE59705220D1 (de) | 2001-12-06 |
| IL129805A0 (en) | 2000-02-29 |
| BG103406A (en) | 2000-03-31 |
| IL129805A (en) | 2002-05-23 |
| SK63099A3 (en) | 1999-11-08 |
| YU33199A (sh) | 2001-09-28 |
| AU4860597A (en) | 1998-06-10 |
| US6464962B2 (en) | 2002-10-15 |
| ATE207873T1 (de) | 2001-11-15 |
| ES2165029T3 (es) | 2002-03-01 |
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