NO309648B1 - Indolderivat og farmasöytisk preparat inneholdende dette - Google Patents

Indolderivat og farmasöytisk preparat inneholdende dette Download PDF

Info

Publication number
NO309648B1
NO309648B1 NO972427A NO972427A NO309648B1 NO 309648 B1 NO309648 B1 NO 309648B1 NO 972427 A NO972427 A NO 972427A NO 972427 A NO972427 A NO 972427A NO 309648 B1 NO309648 B1 NO 309648B1
Authority
NO
Norway
Prior art keywords
group
salt
hydrogen atom
formula
ethanol
Prior art date
Application number
NO972427A
Other languages
English (en)
Norwegian (no)
Other versions
NO972427D0 (no
NO972427L (no
Inventor
Shiro Kato
Hiroshi Harada
Yoshimi Hirokawa
Naoyuki Yoshida
Hitoshi Kawashima
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of NO972427D0 publication Critical patent/NO972427D0/no
Publication of NO972427L publication Critical patent/NO972427L/no
Publication of NO309648B1 publication Critical patent/NO309648B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO972427A 1994-11-29 1997-05-28 Indolderivat og farmasöytisk preparat inneholdende dette NO309648B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP06321402 1994-11-29
PCT/JP1995/002400 WO1996016938A1 (en) 1994-11-29 1995-11-27 Indole derivative

Publications (3)

Publication Number Publication Date
NO972427D0 NO972427D0 (no) 1997-05-28
NO972427L NO972427L (no) 1997-07-28
NO309648B1 true NO309648B1 (no) 2001-03-05

Family

ID=18132155

Family Applications (1)

Application Number Title Priority Date Filing Date
NO972427A NO309648B1 (no) 1994-11-29 1997-05-28 Indolderivat og farmasöytisk preparat inneholdende dette

Country Status (28)

Country Link
US (1) US5817689A (cs)
EP (1) EP0801059B1 (cs)
JP (1) JP3100165B2 (cs)
KR (1) KR100388747B1 (cs)
CN (1) CN1070477C (cs)
AT (1) ATE202559T1 (cs)
AU (1) AU688165B2 (cs)
BR (1) BR9509827A (cs)
CA (1) CA2206307A1 (cs)
CY (1) CY2247B1 (cs)
CZ (1) CZ290871B6 (cs)
DE (1) DE69521529T2 (cs)
DK (1) DK0801059T3 (cs)
ES (1) ES2159648T3 (cs)
FI (1) FI972275L (cs)
GR (1) GR3036148T3 (cs)
HU (1) HUT77308A (cs)
IL (1) IL116178A (cs)
NO (1) NO309648B1 (cs)
NZ (1) NZ295749A (cs)
PL (1) PL181963B1 (cs)
PT (1) PT801059E (cs)
RO (1) RO118426B1 (cs)
RU (1) RU2137759C1 (cs)
SK (1) SK281865B6 (cs)
TW (1) TW349091B (cs)
WO (1) WO1996016938A1 (cs)
ZA (1) ZA9510130B (cs)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010580A1 (es) * 1999-09-03 2001-05-25 Takeda Chemical Industries Ltd Composicion farmaceutica para tratar la diabetes
US6458824B1 (en) * 1999-11-30 2002-10-01 Dainippon Pharmaceutical Co., Ltd. Solid preparation
EP1235801A2 (en) * 1999-11-30 2002-09-04 Dainippon Pharmaceutical Co., Ltd. Solid pharmaceutical preparation
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
EP2335700A1 (en) 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
WO2003092614A2 (en) * 2002-05-02 2003-11-13 Hickle Randall S Lipid removal from the body
CA2488699A1 (en) * 2002-06-12 2003-12-24 Sumitomo Pharmaceuticals Co., Ltd. Indole, indazole, and benzazole derivative
EP1927594A1 (en) * 2003-01-14 2008-06-04 Arena Pharmaceuticals, Inc. 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
CN102558155A (zh) * 2003-01-14 2012-07-11 阿伦纳药品公司 作为代谢调节剂的芳基和杂芳基衍生物及其所涉及的疾病如糖尿病和高血糖症的预防和治疗
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2004089936A1 (ja) * 2003-04-10 2004-10-21 Dainippon Pharmaceutical Co., Ltd. ヘテロアリールスルホン酸アニリド誘導体及びそれを含有する医薬組成物
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
EP1689383B1 (en) * 2003-11-19 2012-10-31 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
UY28758A1 (es) * 2004-02-20 2005-09-30 Boehringer Ingelheim Int Inhibidores de polimerasa viral
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
JP5015154B2 (ja) * 2005-08-12 2012-08-29 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ウイルスポリメラーゼインヒビター
MX2013003184A (es) 2010-09-22 2013-06-07 Arena Pharm Inc Moduladores del receptor gpr119 y el tratamiento de transtornos relacionados con el mismo.
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
JP6660668B2 (ja) * 2014-06-24 2020-03-11 花王株式会社 Ｕｃｐ−１発現促進剤
WO2015199097A1 (ja) * 2014-06-24 2015-12-30 花王株式会社 Ｕｃｐ－１発現促進剤
US10758519B2 (en) 2014-06-24 2020-09-01 Kao Corporation UCP-1 expression promoter
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
PL3310760T3 (pl) 2015-06-22 2023-03-06 Arena Pharmaceuticals, Inc. Krystaliczna sól L-argininy kwasu (R)-2-(7-(4-cyklopentylo-3-(trifluorometylo)benzyloksy)- 1,2,3,4-tetrahydrocyklo-penta[b]indol-3-ilo)octowego do zastosowania w zaburzeniach związanych z receptorem S1P1
AU2019280822A1 (en) 2018-06-06 2021-01-07 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB861428A (en) * 1958-07-14 1961-02-22 Searle & Co Improvements in or relating to indole derivatives
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
JPH06345731A (ja) * 1992-04-28 1994-12-20 Dainippon Pharmaceut Co Ltd ２−〔２−（インドール−３−イル）エチルアミノ〕−１−フェニルエタノール誘導体
JPH0634531A (ja) * 1992-07-14 1994-02-08 Yokogawa Electric Corp 赤外線水分計

Also Published As

Publication number Publication date
EP0801059A1 (en) 1997-10-15
CY2247B1 (en) 2003-07-04
SK281865B6 (sk) 2001-08-06
AU3936695A (en) 1996-06-19
GR3036148T3 (en) 2001-09-28
CN1174549A (zh) 1998-02-25
NO972427D0 (no) 1997-05-28
PL320461A1 (en) 1997-09-29
FI972275A7 (fi) 1997-05-29
PT801059E (pt) 2001-10-30
WO1996016938A1 (en) 1996-06-06
HUT77308A (hu) 1998-03-30
FI972275A0 (fi) 1997-05-29
EP0801059B1 (en) 2001-06-27
JP3100165B2 (ja) 2000-10-16
EP0801059A4 (en) 1998-01-21
NO972427L (no) 1997-07-28
DK0801059T3 (da) 2001-09-24
PL181963B1 (pl) 2001-10-31
CZ290871B6 (cs) 2002-11-13
CN1070477C (zh) 2001-09-05
RU2137759C1 (ru) 1999-09-20
KR100388747B1 (ko) 2004-03-30
DE69521529D1 (de) 2001-08-02
NZ295749A (en) 1998-05-27
IL116178A (en) 2000-07-26
ZA9510130B (en) 1996-06-11
RO118426B1 (ro) 2003-05-30
TW349091B (en) 1999-01-01
CA2206307A1 (en) 1996-06-06
MX9703858A (es) 1997-09-30
SK65697A3 (en) 1998-01-14
ES2159648T3 (es) 2001-10-16
AU688165B2 (en) 1998-03-05
US5817689A (en) 1998-10-06
FI972275L (fi) 1997-05-29
CZ165597A3 (en) 1997-11-12
IL116178A0 (en) 1996-01-31
HK1003886A1 (en) 1998-11-13
DE69521529T2 (de) 2001-10-11
ATE202559T1 (de) 2001-07-15
BR9509827A (pt) 1997-09-30

Similar Documents

Publication Publication Date Title
EP0801059B1 (en) Indole derivative
JPWO1996016938A1 (ja) インドール誘導体
EP0593513B1 (en) Tryptamine analogues, their synthesis and their use as 5-ht1-like receptors or 5-ht2 receptor agonistes
US5036078A (en) Piperidinyl indoles for migraine treatment
IE58122B1 (en) An indole derivative
MXPA05000434A (es) Derivados de hexano [3.1.0] azabiciclo 3,6-disustituido utiles como antagonistas de receptor muscarinico.
EP0775118B1 (en) Benzimidazole derivatives having dopaminergic activity
EP0175525A1 (en) 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones
WO2001034561A1 (en) Processes for the preparation of sumatriptan and related compounds
JPS60158170A (ja) エテニルフェノールインドール誘導体及びそれらの塩、これらの製造方法並びにこれらを含有する薬剤
US4505918A (en) 4-[2-Pyridinylthio(oxy or amino)methyl]-1H-imidazoles and derivatives
CA1243033A (en) Process for preparing 4-¬2- (dialkylamino)ethyl|isatins
JP2003055344A (ja) ３，７−ジ置換インドール誘導体及びそれを含有する医薬組成物
EP0209275B1 (en) Benz-trisubstituted 2-aminotetralins
HK1003886B (en) Indole derivative
MXPA97003858A (en) Derived from in
US4558061A (en) Bronchospasmolytic 1-(3-methanesulfonamido-4-hydroxyphenyl)-2-[(3-(4-acyl-aminophenyl)-imidazolidin-2-one-1-yl)-alkylamino]-ethanols
JPWO1996016038A1 (ja) ２−〔２−（インドール−３−イル）エチルアミノ〕−１−フェニルエタノール誘導体
WO1996016038A1 (en) 2-[2-(indol-3-yl)ethylamino]-1-phenylethanol derivative
IE63264B1 (en) 1((4-Morpholinyl)alkyl)-1h-indoles useful as analgesics and preparation thereof
JPWO2000044721A1 (ja) ３，７−ジ置換インドール誘導体及びそれを含有する医薬組成物
CS200214B2 (cs) Způsob přípravy indazolových derivátů
JPH08231504A (ja) ２−（２−インドリルエチルアミノ）−１−（３−置換フェニル）エタノール誘導体
JP2001039948A (ja) ３，７−ジ置換インドール誘導体及びそれを含有する医薬組成物

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees