NO307417B1 - Ikke-peptidylintegrininhibitorer med spesifisitet for GPIIbIIIa-reseptoren, farmasøytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene til fremstilling av medikamenter - Google Patents

Ikke-peptidylintegrininhibitorer med spesifisitet for GPIIbIIIa-reseptoren, farmasøytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene til fremstilling av medikamenter

Info

Publication number
NO307417B1
NO307417B1 NO941378A NO941378A NO307417B1 NO 307417 B1 NO307417 B1 NO 307417B1 NO 941378 A NO941378 A NO 941378A NO 941378 A NO941378 A NO 941378A NO 307417 B1 NO307417 B1 NO 307417B1
Authority
NO
Norway
Prior art keywords
peptidyl
medicaments
compounds
manufacture
compound
Prior art date
Application number
NO941378A
Other languages
English (en)
Other versions
NO941378D0 (no
NO941378L (no
Inventor
Brent Blackburn
Peter Barker
Thomas Gadek
Robert Mcdowell
Lawrence Mcgee
Todd Somers
Rob Webb
Kirk Robarge
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO941378D0 publication Critical patent/NO941378D0/no
Publication of NO941378L publication Critical patent/NO941378L/no
Publication of NO307417B1 publication Critical patent/NO307417B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO941378A 1991-10-18 1994-04-15 Ikke-peptidylintegrininhibitorer med spesifisitet for GPIIbIIIa-reseptoren, farmasøytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene til fremstilling av medikamenter NO307417B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78147791A 1991-10-18 1991-10-18
US07/866,931 US5250679A (en) 1991-10-18 1992-04-10 Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
PCT/US1992/008788 WO1993008174A1 (en) 1991-10-18 1992-10-15 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR

Publications (3)

Publication Number Publication Date
NO941378D0 NO941378D0 (no) 1994-04-15
NO941378L NO941378L (no) 1994-06-20
NO307417B1 true NO307417B1 (no) 2000-04-03

Family

ID=27119863

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941378A NO307417B1 (no) 1991-10-18 1994-04-15 Ikke-peptidylintegrininhibitorer med spesifisitet for GPIIbIIIa-reseptoren, farmasøytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene til fremstilling av medikamenter

Country Status (15)

Country Link
US (2) US5250679A (no)
EP (1) EP0610334B1 (no)
JP (2) JP3789468B2 (no)
AT (1) ATE133412T1 (no)
AU (1) AU673501B2 (no)
CA (1) CA2119745C (no)
DE (1) DE69207916T2 (no)
DK (1) DK0610334T3 (no)
ES (1) ES2085651T3 (no)
FI (1) FI941222A (no)
GE (1) GEP20032957B (no)
GR (1) GR3019517T3 (no)
MD (1) MD960330A (no)
NO (1) NO307417B1 (no)
WO (1) WO1993008174A1 (no)

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GR3019517T3 (en) 1996-07-31
CA2119745C (en) 2007-02-20
ATE133412T1 (de) 1996-02-15
DE69207916T2 (de) 1996-10-17
DK0610334T3 (da) 1996-06-03
DE69207916D1 (de) 1996-03-07
NO941378D0 (no) 1994-04-15
EP0610334A1 (en) 1994-08-17
AU673501B2 (en) 1996-11-14
FI941222A0 (fi) 1994-03-15
FI941222A (fi) 1994-06-02
CA2119745A1 (en) 1993-04-29
US5403836A (en) 1995-04-04
JP3789468B2 (ja) 2006-06-21
GEP20032957B (en) 2003-04-25
EP0610334B1 (en) 1996-01-24
MD960330A (ro) 1998-05-31
JPH07500341A (ja) 1995-01-12
WO1993008174A1 (en) 1993-04-29
AU2797692A (en) 1993-05-21
ES2085651T3 (es) 1996-06-01
US5250679A (en) 1993-10-05
NO941378L (no) 1994-06-20
JP2003300962A (ja) 2003-10-21

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