DK0693941T3 - Radiomærkede forbindelser til trombe-billeddannelse - Google Patents

Radiomærkede forbindelser til trombe-billeddannelse

Info

Publication number
DK0693941T3
DK0693941T3 DK94921885T DK94921885T DK0693941T3 DK 0693941 T3 DK0693941 T3 DK 0693941T3 DK 94921885 T DK94921885 T DK 94921885T DK 94921885 T DK94921885 T DK 94921885T DK 0693941 T3 DK0693941 T3 DK 0693941T3
Authority
DK
Denmark
Prior art keywords
pct
compounds
methods
sec
date
Prior art date
Application number
DK94921885T
Other languages
English (en)
Inventor
John Lister-James
Edward R Civitello
William Mcbride
Richard T Dean
Original Assignee
Diatide Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diatide Inc filed Critical Diatide Inc
Application granted granted Critical
Publication of DK0693941T3 publication Critical patent/DK0693941T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/082—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being a RGD-containing peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Surgical Instruments (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of Radiation (AREA)
DK94921885T 1993-04-08 1994-04-08 Radiomærkede forbindelser til trombe-billeddannelse DK0693941T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4482593A 1993-04-08 1993-04-08
PCT/US1994/003878 WO1994023758A1 (en) 1993-04-08 1994-04-08 Radiolabeled compounds for thrombus imaging

Publications (1)

Publication Number Publication Date
DK0693941T3 true DK0693941T3 (da) 2002-10-14

Family

ID=21934541

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94921885T DK0693941T3 (da) 1993-04-08 1994-04-08 Radiomærkede forbindelser til trombe-billeddannelse

Country Status (13)

Country Link
US (1) US6056940A (da)
EP (1) EP0693941B1 (da)
JP (1) JP2954355B2 (da)
AT (1) ATE220926T1 (da)
AU (1) AU687080B2 (da)
BR (1) BR1100946A (da)
CA (2) CA2160120A1 (da)
DE (1) DE69431052T2 (da)
DK (1) DK0693941T3 (da)
ES (1) ES2179076T3 (da)
SG (1) SG49788A1 (da)
WO (1) WO1994023758A1 (da)
ZA (1) ZA942439B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830856A (en) * 1991-02-08 1998-11-03 Diatide, Inc. Radiolabeled compounds for thrombus imaging
US5736122A (en) * 1991-02-08 1998-04-07 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5645815A (en) 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
US5997844A (en) * 1991-02-08 1999-12-07 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5849261A (en) * 1991-02-08 1998-12-15 Diatide, Inc. Radiolabeled vasoactive intestinal peptides for diagnosis and therapy
US5443815A (en) * 1991-11-27 1995-08-22 Diatech, Inc. Technetium-99m labeled peptides for imaging
US6019958A (en) * 1991-02-08 2000-02-01 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
ES2141102T3 (es) * 1991-02-08 2000-03-16 Diatide Inc Polipeptidos marcados con tecnecio-99m para la generacion de imagenes.
US5989519A (en) * 1992-03-13 1999-11-23 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
DE69529988T2 (de) * 1994-05-02 2003-12-11 Diatide Inc Technetium-99m markierte bildformungsmittel
US5753206A (en) * 1995-06-07 1998-05-19 Immunomedics, Inc. Radiometal-binding analogues of luteinizing hormone releasing hormone
WO1998002192A1 (en) * 1996-07-12 1998-01-22 Immunomedics, Inc. Radiometal-binding peptide analogues
US5951981A (en) * 1996-12-02 1999-09-14 Diatide, Inc. Thrombolytic agents with antithrombotic activity
US5886142A (en) * 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
DE10005631A1 (de) 2000-02-09 2001-08-23 Max Planck Gesellschaft Arginin-Mimetika als Faktor X¶a¶-Inhibitoren
DE602004027122D1 (de) * 2003-03-26 2010-06-24 Cardiomind Inc Implantatablage-katheter mit elektrolytisch abbaubaren verbindungen

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US4792525A (en) * 1982-08-04 1988-12-20 La Jolla Cancer Research Foundation Tetrapeptide
US4578079A (en) * 1982-08-04 1986-03-25 La Jolla Cancer Research Foundation Tetrapeptide
US5225181A (en) * 1985-06-07 1993-07-06 The Research Foundation Of State University Of New York Radiolabeled antiplatelet monoclonal antibody for imaging in-vivo thrombi
US4877868A (en) * 1986-03-12 1989-10-31 Neorx Corporation Radionuclide antibody coupling
CA1335725C (en) * 1987-09-25 1995-05-30 Stephen W. Hadley Method of diagnosing blood clots using fibrin-binding proteins
DE3855458T2 (de) * 1987-12-10 1996-12-05 Jolla Cancer Res Found Verfahren zur herstellung von conformationnell stabilisierten zelladhäsionspeptiden
EP0381713B1 (en) * 1988-04-29 1994-01-19 Mallinckrodt, Inc. Diaminedithiol chelating agents for radiopharmaceuticals
US5196510A (en) * 1988-12-29 1993-03-23 Cytogen Corporation Molecular recognition units
US4986979A (en) * 1989-03-14 1991-01-22 Neorx Corporation Imaging tissue sites of inflammation
GB8914020D0 (en) * 1989-06-19 1989-08-09 Antisoma Ltd Synthetic peptides for use in thrombus detection
US5384309A (en) * 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
CA2021950A1 (en) * 1989-07-28 1991-01-29 Ruth F. Nutt Fibrinogen receptor antagonists
CA2021951A1 (en) * 1989-07-28 1991-01-29 Ruth F. Nutt Fibrinogen receptor antagonists
EP0410537A1 (en) * 1989-07-28 1991-01-30 Merck & Co. Inc. Fibrinogen receptor antagonists
EP0410539A1 (en) * 1989-07-28 1991-01-30 Merck & Co. Inc. Fibrinogen receptor antagonists
US5443816A (en) * 1990-08-08 1995-08-22 Rhomed Incorporated Peptide-metal ion pharmaceutical preparation and method
US4952562A (en) * 1989-09-29 1990-08-28 Rorer Pharmaceutical Corporation Anti-thrombotic peptides and pseudopeptides
NZ235564A (en) * 1989-10-13 1993-10-26 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical compositions
NZ235563A (en) * 1989-10-13 1993-04-28 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical composition
AU6470590A (en) * 1989-10-23 1991-04-26 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
US5086069A (en) * 1990-02-05 1992-02-04 Rorer Pharmaceutical Corporation Anti-thrombotic peptide and pseudopeptide derivatives
IL97459A0 (en) * 1990-03-09 1992-06-21 Hybritech Inc Trifunctional antibody-like compounds as a combined diagnostic and therapeutic agent
DE69126871T2 (de) * 1990-04-06 1998-03-12 Jolla Cancer Res Found Verfahren und verbindung zur behandlung von thrombose
US5105327A (en) * 1990-05-10 1992-04-14 Uses, Inc. Ac power conditioning circuit
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
ES2141102T3 (es) * 1991-02-08 2000-03-16 Diatide Inc Polipeptidos marcados con tecnecio-99m para la generacion de imagenes.
US5965107A (en) * 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
ES2065182T3 (es) * 1991-03-06 1995-02-01 Searle & Co Derivados de fenilamidinas utiles como inhibidores de la agregacion de plaquetas.
DE69226077T2 (de) * 1991-04-05 1998-12-03 Genentech Inc PLAETTCHENAGGREGATIONSINHIBITOREN MIT HOHER SPEZIFIZITAET ZUM GP IIbIIIa
US5321034A (en) * 1991-05-07 1994-06-14 Merck & Co., Inc. Fibrinogen receptor antagonists
US5220050A (en) * 1991-05-17 1993-06-15 G. D. Searle & Co. Peptide mimetic compounds useful as platelet aggregation inhibitors
AU666318B2 (en) * 1991-06-28 1996-02-08 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
US5250679A (en) * 1991-10-18 1993-10-05 Genentech, Inc. Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
US5508020A (en) * 1992-06-05 1996-04-16 Diatech, Inc. Technetium-99M labeled peptides for imaging
DK0641222T3 (da) * 1992-05-21 2000-12-11 Diatide Inc Peptider mærket med technetium-99m til trombeafbildning
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders

Also Published As

Publication number Publication date
EP0693941A1 (en) 1996-01-31
CA2160120A1 (en) 1994-10-27
ATE220926T1 (de) 2002-08-15
AU7241394A (en) 1994-11-08
JPH08508999A (ja) 1996-09-24
US6056940A (en) 2000-05-02
AU687080B2 (en) 1998-02-19
DE69431052T2 (de) 2003-03-13
WO1994023758A1 (en) 1994-10-27
BR1100946A (pt) 2000-08-08
ZA942439B (en) 1996-01-08
ES2179076T3 (es) 2003-01-16
CA2363780A1 (en) 1994-10-27
SG49788A1 (en) 1998-06-15
CA2363780C (en) 2003-01-07
DE69431052D1 (de) 2002-08-29
JP2954355B2 (ja) 1999-09-27
EP0693941B1 (en) 2002-07-24

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