GR3019517T3 - Nonpeptidyl integrin inhibitors having specificity for the gpii b?iii a? receptor. - Google Patents

Nonpeptidyl integrin inhibitors having specificity for the gpii b?iii a? receptor.

Info

Publication number
GR3019517T3
GR3019517T3 GR960400905T GR960400905T GR3019517T3 GR 3019517 T3 GR3019517 T3 GR 3019517T3 GR 960400905 T GR960400905 T GR 960400905T GR 960400905 T GR960400905 T GR 960400905T GR 3019517 T3 GR3019517 T3 GR 3019517T3
Authority
GR
Greece
Prior art keywords
receptor
nonpeptidyl
gpii
specificity
iii
Prior art date
Application number
GR960400905T
Other languages
English (en)
Inventor
Brent Blackburn
Peter Barker
Thomas Gadek
Robert Mcdowell
Lawrence Mcgee
Todd Somers
Rob Webb
Kirk Robarge
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of GR3019517T3 publication Critical patent/GR3019517T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02—Seven-membered rings
    • C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR960400905T 1991-10-18 1996-04-02 Nonpeptidyl integrin inhibitors having specificity for the gpii b?iii a? receptor. GR3019517T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78147791A 1991-10-18 1991-10-18
US07/866,931 US5250679A (en) 1991-10-18 1992-04-10 Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor
PCT/US1992/008788 WO1993008174A1 (en) 1991-10-18 1992-10-15 NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPIIbIIIa RECEPTOR

Publications (1)

Publication Number Publication Date
GR3019517T3 true GR3019517T3 (en) 1996-07-31

Family

ID=27119863

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960400905T GR3019517T3 (en) 1991-10-18 1996-04-02 Nonpeptidyl integrin inhibitors having specificity for the gpii b?iii a? receptor.

Country Status (15)

Country Link
US (2) US5250679A (el)
EP (1) EP0610334B1 (el)
JP (2) JP3789468B2 (el)
AT (1) ATE133412T1 (el)
AU (1) AU673501B2 (el)
CA (1) CA2119745C (el)
DE (1) DE69207916T2 (el)
DK (1) DK0610334T3 (el)
ES (1) ES2085651T3 (el)
FI (1) FI941222A (el)
GE (1) GEP20032957B (el)
GR (1) GR3019517T3 (el)
MD (1) MD960330A (el)
NO (1) NO307417B1 (el)
WO (1) WO1993008174A1 (el)

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Also Published As

Publication number Publication date
EP0610334B1 (en) 1996-01-24
DK0610334T3 (da) 1996-06-03
US5403836A (en) 1995-04-04
WO1993008174A1 (en) 1993-04-29
US5250679A (en) 1993-10-05
AU673501B2 (en) 1996-11-14
EP0610334A1 (en) 1994-08-17
GEP20032957B (en) 2003-04-25
FI941222A0 (fi) 1994-03-15
ATE133412T1 (de) 1996-02-15
CA2119745A1 (en) 1993-04-29
DE69207916D1 (de) 1996-03-07
NO941378L (no) 1994-06-20
DE69207916T2 (de) 1996-10-17
CA2119745C (en) 2007-02-20
JP3789468B2 (ja) 2006-06-21
JP2003300962A (ja) 2003-10-21
NO941378D0 (no) 1994-04-15
ES2085651T3 (es) 1996-06-01
MD960330A (ro) 1998-05-31
FI941222A (fi) 1994-06-02
AU2797692A (en) 1993-05-21
NO307417B1 (no) 2000-04-03
JPH07500341A (ja) 1995-01-12

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