NO307300B1 - Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike - Google Patents

Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike

Info

Publication number
NO307300B1
NO307300B1 NO962998A NO962998A NO307300B1 NO 307300 B1 NO307300 B1 NO 307300B1 NO 962998 A NO962998 A NO 962998A NO 962998 A NO962998 A NO 962998A NO 307300 B1 NO307300 B1 NO 307300B1
Authority
NO
Norway
Prior art keywords
group
alkyl group
aryl
pyrrolopyridazine derivatives
halogeno
Prior art date
Application number
NO962998A
Other languages
English (en)
Norwegian (no)
Other versions
NO962998D0 (no
NO962998L (no
Inventor
Tomio Kimura
Yoshimi Fujihara
Nobuhiko Shibakawa
Hiroshi Fujiwara
Etsuro Itoh
Keiji Matsunobu
Keiichi Tabata
Hiroshi Yasuda
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of NO962998D0 publication Critical patent/NO962998D0/no
Publication of NO962998L publication Critical patent/NO962998L/no
Publication of NO307300B1 publication Critical patent/NO307300B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO962998A 1994-01-19 1996-07-18 Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike NO307300B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP398894 1994-01-19
PCT/JP1995/000038 WO1995019980A1 (en) 1994-01-19 1995-01-18 Pyrrolopyridazine derivative

Publications (3)

Publication Number Publication Date
NO962998D0 NO962998D0 (no) 1996-07-18
NO962998L NO962998L (no) 1996-09-17
NO307300B1 true NO307300B1 (no) 2000-03-13

Family

ID=11572411

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962998A NO307300B1 (no) 1994-01-19 1996-07-18 Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike

Country Status (18)

Country Link
US (1) US6063782A (cs)
EP (1) EP0742218B1 (cs)
KR (1) KR100361199B1 (cs)
CN (1) CN1044811C (cs)
AT (1) ATE229020T1 (cs)
AU (1) AU680998B2 (cs)
CZ (1) CZ283216B6 (cs)
DE (1) DE69529056T2 (cs)
DK (1) DK0742218T3 (cs)
ES (1) ES2185693T3 (cs)
FI (1) FI112488B (cs)
HU (1) HU225920B1 (cs)
MX (1) MX9602850A (cs)
NO (1) NO307300B1 (cs)
NZ (1) NZ278675A (cs)
PT (1) PT742218E (cs)
RU (1) RU2146257C1 (cs)
WO (1) WO1995019980A1 (cs)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316429B1 (en) * 1997-05-07 2001-11-13 Sugen, Inc. Bicyclic protein kinase inhibitors
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
PL204437B1 (pl) * 1999-05-21 2010-01-29 Bristol Myers Squibb Co Pochodna pirolotriazyny i jej zastosowanie oraz kompozycja farmaceutyczna i jej zastosowanie
TWI287014B (en) 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
ES2286094T3 (es) * 2000-02-10 2007-12-01 Sankyo Company, Limited Compuesto de pirrolopiridacina.
FR2849025B1 (fr) * 2002-12-20 2005-10-14 Rhodia Chimie Sa Esters d'allyle substitue par un groupe difluoromethylene, leur procede de synthese et leur utilisation
RU2186108C1 (ru) * 2001-04-24 2002-07-27 Институт органической химии им. Н.Д.Зелинского РАН Необратимый ингибитор н,к - аденозинтрифосфатазы
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
BRPI0213586B1 (pt) * 2001-09-27 2017-06-20 Monsanto Technology Llc Compositions, method of protecting a plant or its propagation materials against fungus disease or damage, as a controlled release formulation
AU2003266621A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for treatment for or prevention of visceral pain
AU2003266622A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for inhibiting increase in blood gastrin concentration
JP4671104B2 (ja) * 2003-01-09 2011-04-13 アステラス製薬株式会社 ピロロピリダジン誘導体
EP1611901B1 (en) * 2003-03-13 2013-07-10 Eisai R&D Management Co., Ltd. Preventive or remedy for teeth grinding
DK1784403T3 (da) * 2004-09-03 2013-10-21 Yuhan Corp Pyrrolo[3,2-b]pyridinderivater samt fremgangsmåder til deres fremstilling
CA2579083C (en) * 2004-09-03 2011-06-14 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
BRPI0514843A (pt) * 2004-09-03 2008-06-24 Yuhan Corp derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos
KR101137168B1 (ko) * 2005-03-09 2012-04-19 주식회사유한양행 피롤로［２,３-ｄ］피리다진 유도체 및 그의 제조방법
ES2383969T3 (es) * 2006-01-16 2012-06-27 Ube Industries, Ltd. Compuesto de pirrolopiridazinona como inhibidor de PDE4
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
BR112012018631A8 (pt) 2010-01-28 2017-12-19 President And Fellows Of Harvard Colege composições e métodos para intensificação da atividade do proteassoma
HUE044867T2 (hu) 2011-05-12 2019-11-28 Proteostasis Therapeutics Inc Proteosztázis szabályzók
US9849135B2 (en) 2013-01-25 2017-12-26 President And Fellows Of Harvard College USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
WO2016115054A2 (en) * 2015-01-13 2016-07-21 Vivreon Biosciences, Llc Modulators of ca2+ release-activated ca2+ (crac) channels and pharmaceutical uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
PT97467A (pt) * 1990-04-27 1992-01-31 Byk Gulden Lomberg Chem Fab Processo para preparacao de novas piridazinas e de composicoes farmaceuticas que as contem
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
AU8712191A (en) * 1990-10-15 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazines
AU2870492A (en) * 1991-10-25 1993-05-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyrrolo-pyridazines with gastro-intestinal protective action

Also Published As

Publication number Publication date
NO962998D0 (no) 1996-07-18
DE69529056D1 (de) 2003-01-16
EP0742218B1 (en) 2002-12-04
WO1995019980A1 (en) 1995-07-27
PT742218E (pt) 2003-02-28
MX9602850A (es) 1997-06-28
HK1015609A1 (en) 1999-10-15
FI962892A0 (fi) 1996-07-18
NZ278675A (en) 1997-07-27
AU1465795A (en) 1995-08-08
FI112488B (fi) 2003-12-15
HUT77998A (hu) 1999-04-28
ES2185693T3 (es) 2003-05-01
DE69529056T2 (de) 2003-11-13
CN1143964A (zh) 1997-02-26
RU2146257C1 (ru) 2000-03-10
FI962892A7 (fi) 1996-09-16
CN1044811C (zh) 1999-08-25
KR100361199B1 (ko) 2003-04-16
DK0742218T3 (da) 2003-01-13
CZ208496A3 (en) 1996-12-11
ATE229020T1 (de) 2002-12-15
US6063782A (en) 2000-05-16
AU680998B2 (en) 1997-08-14
NO962998L (no) 1996-09-17
EP0742218A4 (en) 1997-07-09
CZ283216B6 (cs) 1998-02-18
EP0742218A1 (en) 1996-11-13
HU225920B1 (en) 2008-01-28
HU9601967D0 (en) 1996-09-30

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