NO307300B1 - Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike - Google Patents

Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike

Info

Publication number
NO307300B1
NO307300B1 NO962998A NO962998A NO307300B1 NO 307300 B1 NO307300 B1 NO 307300B1 NO 962998 A NO962998 A NO 962998A NO 962998 A NO962998 A NO 962998A NO 307300 B1 NO307300 B1 NO 307300B1
Authority
NO
Norway
Prior art keywords
group
alkyl group
aryl
pyrrolopyridazine derivatives
halogeno
Prior art date
Application number
NO962998A
Other languages
English (en)
Other versions
NO962998D0 (no
NO962998L (no
Inventor
Tomio Kimura
Yoshimi Fujihara
Nobuhiko Shibakawa
Hiroshi Fujiwara
Etsuro Itoh
Keiji Matsunobu
Keiichi Tabata
Hiroshi Yasuda
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of NO962998D0 publication Critical patent/NO962998D0/no
Publication of NO962998L publication Critical patent/NO962998L/no
Publication of NO307300B1 publication Critical patent/NO307300B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
NO962998A 1994-01-19 1996-07-18 Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike NO307300B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP398894 1994-01-19
PCT/JP1995/000038 WO1995019980A1 (fr) 1994-01-19 1995-01-18 Derive de pyrrolopyridazine

Publications (3)

Publication Number Publication Date
NO962998D0 NO962998D0 (no) 1996-07-18
NO962998L NO962998L (no) 1996-09-17
NO307300B1 true NO307300B1 (no) 2000-03-13

Family

ID=11572411

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962998A NO307300B1 (no) 1994-01-19 1996-07-18 Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike

Country Status (19)

Country Link
US (1) US6063782A (no)
EP (1) EP0742218B1 (no)
KR (1) KR100361199B1 (no)
CN (1) CN1044811C (no)
AT (1) ATE229020T1 (no)
AU (1) AU680998B2 (no)
CZ (1) CZ283216B6 (no)
DE (1) DE69529056T2 (no)
DK (1) DK0742218T3 (no)
ES (1) ES2185693T3 (no)
FI (1) FI112488B (no)
HK (1) HK1015609A1 (no)
HU (1) HU225920B1 (no)
MX (1) MX9602850A (no)
NO (1) NO307300B1 (no)
NZ (1) NZ278675A (no)
PT (1) PT742218E (no)
RU (1) RU2146257C1 (no)
WO (1) WO1995019980A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316429B1 (en) * 1997-05-07 2001-11-13 Sugen, Inc. Bicyclic protein kinase inhibitors
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
TWI287014B (en) * 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
WO2001058901A1 (fr) * 2000-02-10 2001-08-16 Sankyo Company, Limited Compose de pyrrolopyridazine
FR2849025B1 (fr) * 2002-12-20 2005-10-14 Rhodia Chimie Sa Esters d'allyle substitue par un groupe difluoromethylene, leur procede de synthese et leur utilisation
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
BR0213586A (pt) * 2001-09-27 2004-10-26 Monsanto Technology Llc Composições fungicidas e suas aplicações em agricultura
WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
TW200418479A (en) * 2002-09-25 2004-10-01 Sankyo Co Pharmaceutical compositions for the treatment or prevention of visceral pains
US7608625B2 (en) * 2003-03-13 2009-10-27 Eisai R & D Management Co., Ltd. Method for treating bruxism and bruxism-related diseases
CA2579083C (en) * 2004-09-03 2011-06-14 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
ES2426920T3 (es) * 2004-09-03 2013-10-25 Yuhan Corporation Derivados de pirrolo[3,2-B]piridina y procesos para su preparación
AU2005280738B2 (en) * 2004-09-03 2010-11-25 Yuhan Corporation Pyrrolo(3,2-c)pyridine derivatives and processes for the preparation thereof
KR101137168B1 (ko) * 2005-03-09 2012-04-19 주식회사유한양행 피롤로［２,３-ｄ］피리다진 유도체 및 그의 제조방법
ATE548369T1 (de) * 2006-01-16 2012-03-15 Ube Industries Pyrrolopyridazinonverbindung als pde4 inhibitor
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
RU2012136451A (ru) 2010-01-28 2014-03-10 Президент Энд Феллоуз Оф Гарвард Колледж Композиции и способы улучшения активности протеасомы
DK2707101T3 (da) 2011-05-12 2019-05-13 Proteostasis Therapeutics Inc Proteostaseregulatorer
US9849135B2 (en) 2013-01-25 2017-12-26 President And Fellows Of Harvard College USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
WO2016115054A2 (en) * 2015-01-13 2016-07-21 Vivreon Biosciences, Llc Modulators of ca2+ release-activated ca2+ (crac) channels and pharmaceutical uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
IL97931A0 (en) * 1990-04-27 1992-06-21 Byk Gulden Lomberg Chem Fab Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
WO1992006979A1 (de) * 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazine
ATE179419T1 (de) * 1991-10-25 1999-05-15 Byk Gulden Lomberg Chem Fab Pyrrolo-pyridazine mit magen- und darmschutzwirkungen

Also Published As

Publication number Publication date
PT742218E (pt) 2003-02-28
AU1465795A (en) 1995-08-08
EP0742218A4 (en) 1997-07-09
NO962998D0 (no) 1996-07-18
WO1995019980A1 (fr) 1995-07-27
ES2185693T3 (es) 2003-05-01
HU225920B1 (en) 2008-01-28
EP0742218A1 (en) 1996-11-13
FI112488B (fi) 2003-12-15
MX9602850A (es) 1997-06-28
DK0742218T3 (da) 2003-01-13
DE69529056D1 (de) 2003-01-16
FI962892A (fi) 1996-09-16
FI962892A0 (fi) 1996-07-18
CZ283216B6 (cs) 1998-02-18
KR100361199B1 (ko) 2003-04-16
CN1044811C (zh) 1999-08-25
ATE229020T1 (de) 2002-12-15
EP0742218B1 (en) 2002-12-04
NO962998L (no) 1996-09-17
DE69529056T2 (de) 2003-11-13
CZ208496A3 (en) 1996-12-11
AU680998B2 (en) 1997-08-14
HK1015609A1 (en) 1999-10-15
HUT77998A (hu) 1999-04-28
NZ278675A (en) 1997-07-27
CN1143964A (zh) 1997-02-26
US6063782A (en) 2000-05-16
HU9601967D0 (en) 1996-09-30
RU2146257C1 (ru) 2000-03-10

Similar Documents

Publication Publication Date Title
NO307300B1 (no) Pyrrolopyridazinderivater og antimagesårmidler som inneholder slike
IL205420A (en) Immunogoldular and Derivative Compounds, Pharmaceutical Compounds in the Treatment of Inflammatory Stomach and Gastrointestinal Disorders
DK0683773T3 (da) Hypolopidæmiske kondenserede 1,4-thiazepiner
CA2335285A1 (en) Bicyclic piperidine and piperazine compounds having 5-ht6 receptor affinity
NO20015172L (no) 1-metyl-erytromycin-derivater
NO20014925D0 (no) Farmasöytiske forbindelser
DK243185A (da) Aminderivater, fremgangsmaade til fremstilling deraf og fungicider indeholdende dem
DK0974589T3 (da) Benzimidazolderivater og farmaceutiske acceptable salte deraf
DK0688218T3 (da) Interleukin-1-inhibitor
GR3036704T3 (en) Thiazolidinone compounds or angina pectoris remedy or preventive containing the same as active ingredient
NO20016099L (no) Optisk aktive pyrrolopyridazinforbindelser
EP0297593A3 (en) Treating agent for heart failure
CA2181553A1 (en) Pyrrolopyridazine derivatives
AP2003002831A0 (en) Derivatives of etoposide and analogs, and pharmaceutical compositions containing them
DK269785A (da) 4(5-)substituerede imidazoler og fremgangsmaade til fremstilling heraf
EP1197211A4 (en) CANCER PREVENTION AND TREATMENT ACTIVE INGREDIENTS
EP1201664A4 (en) BEMZIMIDAZOLE COMPOUNDS AND DRUGS CONTAINING THEM
RU94011270A (ru) Гетероциклические ингибаторы фарнезилпротеинтрансферазы, промежуточные соединения, способы лечения