DK0688218T3 - Interleukin-1-inhibitor - Google Patents

Interleukin-1-inhibitor

Info

Publication number
DK0688218T3
DK0688218T3 DK94907087T DK94907087T DK0688218T3 DK 0688218 T3 DK0688218 T3 DK 0688218T3 DK 94907087 T DK94907087 T DK 94907087T DK 94907087 T DK94907087 T DK 94907087T DK 0688218 T3 DK0688218 T3 DK 0688218T3
Authority
DK
Denmark
Prior art keywords
interleukin
lower alkyl
halogen atom
alkyl group
inhibiting agent
Prior art date
Application number
DK94907087T
Other languages
English (en)
Inventor
Masakazu Adachi
Yukihisa Ono
Hisashi Tamaoka
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0688218T3 publication Critical patent/DK0688218T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK94907087T 1993-03-10 1994-02-22 Interleukin-1-inhibitor DK0688218T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4850193 1993-03-10
PCT/JP1994/000266 WO1994020105A1 (en) 1993-03-10 1994-02-22 Interleukin-1 inhibitor

Publications (1)

Publication Number Publication Date
DK0688218T3 true DK0688218T3 (da) 2000-03-13

Family

ID=12805138

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94907087T DK0688218T3 (da) 1993-03-10 1994-02-22 Interleukin-1-inhibitor

Country Status (11)

Country Link
EP (1) EP0688218B1 (da)
KR (1) KR100191943B1 (da)
CN (1) CN1088586C (da)
AT (1) ATE186642T1 (da)
AU (1) AU676267B2 (da)
DE (1) DE69421694T2 (da)
DK (1) DK0688218T3 (da)
ES (1) ES2140531T3 (da)
GR (1) GR3032492T3 (da)
TW (1) TW244336B (da)
WO (1) WO1994020105A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750224B1 (en) 1999-05-07 2004-06-15 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
US6514986B2 (en) 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
TWI287987B (en) * 2000-08-14 2007-10-11 Senju Pharma Co Cytokine inhibitor
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
US7164023B2 (en) 2003-09-04 2007-01-16 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
JPS5995220A (ja) * 1982-11-22 1984-06-01 Ajinomoto Co Inc 免疫療法剤
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4894374A (en) * 1988-08-17 1990-01-16 American Home Products Corporation Substituted 1,2-dihydro-4h-3,1-benzoxazin-4-one derivatives inhibitors of interleukin 1
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions

Also Published As

Publication number Publication date
WO1994020105A1 (en) 1994-09-15
GR3032492T3 (en) 2000-05-31
DE69421694D1 (en) 1999-12-23
EP0688218B1 (en) 1999-11-17
TW244336B (da) 1995-04-01
KR100191943B1 (ko) 1999-06-15
AU6046194A (en) 1994-09-26
ES2140531T3 (es) 2000-03-01
CN1118991A (zh) 1996-03-20
ATE186642T1 (de) 1999-12-15
EP0688218A1 (en) 1995-12-27
DE69421694T2 (de) 2000-05-25
AU676267B2 (en) 1997-03-06
KR960700720A (ko) 1996-02-24
CN1088586C (zh) 2002-08-07

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