GR3032492T3 - Interleukin-1 inhibitor - Google Patents

Interleukin-1 inhibitor

Info

Publication number
GR3032492T3
GR3032492T3 GR20000400186T GR20000400186T GR3032492T3 GR 3032492 T3 GR3032492 T3 GR 3032492T3 GR 20000400186 T GR20000400186 T GR 20000400186T GR 20000400186 T GR20000400186 T GR 20000400186T GR 3032492 T3 GR3032492 T3 GR 3032492T3
Authority
GR
Greece
Prior art keywords
interleukin
lower alkyl
halogen atom
alkyl group
inhibiting agent
Prior art date
Application number
GR20000400186T
Other languages
English (en)
Inventor
Masakazu Adachi
Hisashi Tamaoka
Yukihisa Ono
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of GR3032492T3 publication Critical patent/GR3032492T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
GR20000400186T 1993-03-10 2000-01-27 Interleukin-1 inhibitor GR3032492T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4850193 1993-03-10
PCT/JP1994/000266 WO1994020105A1 (en) 1993-03-10 1994-02-22 Interleukin-1 inhibitor

Publications (1)

Publication Number Publication Date
GR3032492T3 true GR3032492T3 (en) 2000-05-31

Family

ID=12805138

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400186T GR3032492T3 (en) 1993-03-10 2000-01-27 Interleukin-1 inhibitor

Country Status (11)

Country Link
EP (1) EP0688218B1 (el)
KR (1) KR100191943B1 (el)
CN (1) CN1088586C (el)
AT (1) ATE186642T1 (el)
AU (1) AU676267B2 (el)
DE (1) DE69421694T2 (el)
DK (1) DK0688218T3 (el)
ES (1) ES2140531T3 (el)
GR (1) GR3032492T3 (el)
TW (1) TW244336B (el)
WO (1) WO1994020105A1 (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6750224B1 (en) 1999-05-07 2004-06-15 Wockhardt Limited Antibacterial optically pure benzoquinolizine carboxylic acids, processes, compositions and methods of treatment
US6514986B2 (en) 2000-11-22 2003-02-04 Wockhardt Limited Chiral fluoroquinolone arginine salt forms
US6608078B2 (en) 2000-05-08 2003-08-19 Wockhardt Limited Antibacterial chiral 8-(substituted piperidino)-benzo [i,j] quinolizines, processes, compositions and methods of treatment
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
TWI287987B (en) * 2000-08-14 2007-10-11 Senju Pharma Co Cytokine inhibitor
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6664267B1 (en) 2002-05-28 2003-12-16 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
US7164023B2 (en) 2003-09-04 2007-01-16 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
JPS5995220A (ja) * 1982-11-22 1984-06-01 Ajinomoto Co Inc 免疫療法剤
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US4894374A (en) * 1988-08-17 1990-01-16 American Home Products Corporation Substituted 1,2-dihydro-4h-3,1-benzoxazin-4-one derivatives inhibitors of interleukin 1
US5064837A (en) * 1989-11-13 1991-11-12 Schering Corporation 3-substituted-1-aryl-2(h)-quinolones and their pharmaceutical compositions

Also Published As

Publication number Publication date
WO1994020105A1 (en) 1994-09-15
DE69421694D1 (en) 1999-12-23
EP0688218B1 (en) 1999-11-17
TW244336B (el) 1995-04-01
DK0688218T3 (da) 2000-03-13
KR100191943B1 (ko) 1999-06-15
AU6046194A (en) 1994-09-26
ES2140531T3 (es) 2000-03-01
CN1118991A (zh) 1996-03-20
ATE186642T1 (de) 1999-12-15
EP0688218A1 (en) 1995-12-27
DE69421694T2 (de) 2000-05-25
AU676267B2 (en) 1997-03-06
KR960700720A (ko) 1996-02-24
CN1088586C (zh) 2002-08-07

Similar Documents

Publication Publication Date Title
MX9804457A (es) Inhibidores de las metaloproteinasas, composiciones farmaceuticas que los contienen y sus usos farmaceuticos y metodos y compuestos intermedios utiles para su preparacion.
NO950297L (no) Prolinamidderivater
ATE204875T1 (de) Fungizide tetrahydrofurane
HK1003708A1 (en) Peripheral vasodilating agent containing n-acylated 4-amino piperidine derivatives as active ingredients
AU7517400A (en) N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
EA200101077A1 (ru) Композиция для профилактики или лечения слабоумия, включающая производное гидроксикоричной кислоты или экстракт растения рода angelicae, содержащий его
WO2001003685A3 (en) Novel prodrugs for antimicrobial amidines
EP0889041A4 (en) NEW IRIDOID DERIVATIVES AND NEOVASCULARIZATION INHIBITORS THAT CONTAIN THESE AS ACTIVE INGREDIENTS
UA32427C2 (uk) Застосування бензотіофенів або їх фармацевтично прийнятних солей або сольватів для інгібування ангіогенезу і/або ангіогенних захворювань
DE69421694D1 (en) Interleukin-1 inhibitor
DK0882728T3 (da) 1-methylcarbapenemderivater
EP0838223A4 (en) CEREBRAL EDEMA INHIBITOR
MX9804828A (es) Benzotiazolona etanaminas biologicamente activas.
NZ332687A (en) use of 1-methyl-carbapenem derivatives as anti-helicobacter pylori agents
CA2118425A1 (en) Benzothiazolesulfonamide derivative, Method for Preparing the Same, and Use Thereof
TW280810B (el)
DE69528984D1 (de) Hemmung der leukotrienbiosynthese mittels harnstoffderivaten
PH23966A (en) Imidazoquinozoline compounds as agent for treatment of nephritis
DE3782229D1 (de) Verwendung von 2-oxo-imidazolidin-derivaten zur behandlung von nierenkrankheiten.
NO951985L (no) Acetamidderivat