HK1015609A1 - Pyrrolopyridazine derivative - Google Patents

Pyrrolopyridazine derivative

Info

Publication number
HK1015609A1
HK1015609A1 HK98112609A HK98112609A HK1015609A1 HK 1015609 A1 HK1015609 A1 HK 1015609A1 HK 98112609 A HK98112609 A HK 98112609A HK 98112609 A HK98112609 A HK 98112609A HK 1015609 A1 HK1015609 A1 HK 1015609A1
Authority
HK
Hong Kong
Prior art keywords
group
alkyl group
aryl
halogeno
cycloalkyl
Prior art date
Application number
HK98112609A
Other languages
English (en)
Inventor
Tomio Kimura
Yoshimi Fujihara
Nobuhiko Shibakawa
Hiroshi Fujiwara
Etsuro Itoh
Keiji Matsunobu
Keiichi Tabata
Hiroshi Yasuda
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of HK1015609A1 publication Critical patent/HK1015609A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
HK98112609A 1994-01-19 1998-12-01 Pyrrolopyridazine derivative HK1015609A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP398894 1994-01-19
PCT/JP1995/000038 WO1995019980A1 (fr) 1994-01-19 1995-01-18 Derive de pyrrolopyridazine

Publications (1)

Publication Number Publication Date
HK1015609A1 true HK1015609A1 (en) 1999-10-15

Family

ID=11572411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98112609A HK1015609A1 (en) 1994-01-19 1998-12-01 Pyrrolopyridazine derivative

Country Status (19)

Country Link
US (1) US6063782A (no)
EP (1) EP0742218B1 (no)
KR (1) KR100361199B1 (no)
CN (1) CN1044811C (no)
AT (1) ATE229020T1 (no)
AU (1) AU680998B2 (no)
CZ (1) CZ283216B6 (no)
DE (1) DE69529056T2 (no)
DK (1) DK0742218T3 (no)
ES (1) ES2185693T3 (no)
FI (1) FI112488B (no)
HK (1) HK1015609A1 (no)
HU (1) HU225920B1 (no)
MX (1) MX9602850A (no)
NO (1) NO307300B1 (no)
NZ (1) NZ278675A (no)
PT (1) PT742218E (no)
RU (1) RU2146257C1 (no)
WO (1) WO1995019980A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316429B1 (en) * 1997-05-07 2001-11-13 Sugen, Inc. Bicyclic protein kinase inhibitors
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
TWI287014B (en) * 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
EP1254907B1 (en) 2000-02-10 2007-05-09 Sankyo Company, Limited Pyrrolopyridazine compound
FR2849025B1 (fr) * 2002-12-20 2005-10-14 Rhodia Chimie Sa Esters d'allyle substitue par un groupe difluoromethylene, leur procede de synthese et leur utilisation
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
BR0213586A (pt) * 2001-09-27 2004-10-26 Monsanto Technology Llc Composições fungicidas e suas aplicações em agricultura
TW200420293A (en) * 2002-09-25 2004-10-16 Sankyo Co Pharmaceutical compositions for the reduction of gastric acid concentration in blood
AU2003266621A1 (en) * 2002-09-25 2004-04-19 Sankyo Company, Limited Medicinal composition for treatment for or prevention of visceral pain
EP1611901B1 (en) * 2003-03-13 2013-07-10 Eisai R&D Management Co., Ltd. Preventive or remedy for teeth grinding
WO2006025715A1 (en) * 2004-09-03 2006-03-09 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
BRPI0514843A (pt) * 2004-09-03 2008-06-24 Yuhan Corp derivados de pirrolo[3,2-c] piridina e processos para a preparação dos mesmos
JP4989478B2 (ja) * 2004-09-03 2012-08-01 ユーハン・コーポレイション ピロロ［３，２−ｂ］ピリジン誘導体及びその製造方法
KR101137168B1 (ko) * 2005-03-09 2012-04-19 주식회사유한양행 피롤로［２,３-ｄ］피리다진 유도체 및 그의 제조방법
CN101374844B (zh) * 2006-01-16 2012-10-24 宇部兴产株式会社 吡咯并哒嗪酮化合物
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
AU2011210765A1 (en) 2010-01-28 2012-09-13 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
EP3552664A1 (en) * 2011-05-12 2019-10-16 Proteostasis Therapeutics, Inc. Proteostasis regulators
US9849135B2 (en) 2013-01-25 2017-12-26 President And Fellows Of Harvard College USP14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
CN107207431B (zh) * 2015-01-13 2021-02-09 维夫雷昂生物科学有限责任公司 Ca2+释放激活的Ca2+(CRAC)通道的调节剂及其药物用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
WO1991017164A1 (de) * 1990-04-27 1991-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue pyridazine
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
WO1992006979A1 (de) * 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazine
DK0609328T3 (da) * 1991-10-25 1999-10-25 Byk Gulden Lomberg Chem Fab Pyrrolo-pyridaziner med gastro-intestinal beskyttelsesvirkning

Also Published As

Publication number Publication date
EP0742218A1 (en) 1996-11-13
RU2146257C1 (ru) 2000-03-10
ES2185693T3 (es) 2003-05-01
EP0742218B1 (en) 2002-12-04
DK0742218T3 (da) 2003-01-13
AU680998B2 (en) 1997-08-14
CZ208496A3 (en) 1996-12-11
EP0742218A4 (en) 1997-07-09
ATE229020T1 (de) 2002-12-15
NO962998D0 (no) 1996-07-18
HU9601967D0 (en) 1996-09-30
KR100361199B1 (ko) 2003-04-16
MX9602850A (es) 1997-06-28
CN1143964A (zh) 1997-02-26
FI962892A (fi) 1996-09-16
FI962892A0 (fi) 1996-07-18
CZ283216B6 (cs) 1998-02-18
NZ278675A (en) 1997-07-27
WO1995019980A1 (fr) 1995-07-27
HU225920B1 (en) 2008-01-28
US6063782A (en) 2000-05-16
HUT77998A (hu) 1999-04-28
NO962998L (no) 1996-09-17
FI112488B (fi) 2003-12-15
NO307300B1 (no) 2000-03-13
DE69529056T2 (de) 2003-11-13
PT742218E (pt) 2003-02-28
CN1044811C (zh) 1999-08-25
AU1465795A (en) 1995-08-08
DE69529056D1 (de) 2003-01-16

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090118