NO306672B1 - N,N-dietyl-8,8-dipropyl-2-azaspiro[4,5]decan-2-propanamindimaleat, farmasöytisk blanding omfattende forbindelsen samt anvendelse derav - Google Patents

N,N-dietyl-8,8-dipropyl-2-azaspiro[4,5]decan-2-propanamindimaleat, farmasöytisk blanding omfattende forbindelsen samt anvendelse derav

Info

Publication number
NO306672B1
NO306672B1 NO962931A NO962931A NO306672B1 NO 306672 B1 NO306672 B1 NO 306672B1 NO 962931 A NO962931 A NO 962931A NO 962931 A NO962931 A NO 962931A NO 306672 B1 NO306672 B1 NO 306672B1
Authority
NO
Norway
Prior art keywords
dimethylate
propanamine
azaspiro
dipropyl
decane
Prior art date
Application number
NO962931A
Other languages
English (en)
Norwegian (no)
Other versions
NO962931D0 (no
NO962931L (no
Inventor
Raymond E Dagger
Carolyn W Grady
Original Assignee
Anormed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anormed Inc filed Critical Anormed Inc
Publication of NO962931D0 publication Critical patent/NO962931D0/no
Publication of NO962931L publication Critical patent/NO962931L/no
Publication of NO306672B1 publication Critical patent/NO306672B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
NO962931A 1995-07-13 1996-07-12 N,N-dietyl-8,8-dipropyl-2-azaspiro[4,5]decan-2-propanamindimaleat, farmasöytisk blanding omfattende forbindelsen samt anvendelse derav NO306672B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US113995P 1995-07-13 1995-07-13
US1606596P 1996-04-23 1996-04-23

Publications (3)

Publication Number Publication Date
NO962931D0 NO962931D0 (no) 1996-07-12
NO962931L NO962931L (no) 1997-01-14
NO306672B1 true NO306672B1 (no) 1999-12-06

Family

ID=26668617

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962931A NO306672B1 (no) 1995-07-13 1996-07-12 N,N-dietyl-8,8-dipropyl-2-azaspiro[4,5]decan-2-propanamindimaleat, farmasöytisk blanding omfattende forbindelsen samt anvendelse derav

Country Status (29)

Country Link
EP (1) EP0753512B1 (cs)
JP (1) JP3949750B2 (cs)
KR (1) KR100404832B1 (cs)
CN (1) CN1067378C (cs)
AR (1) AR003452A1 (cs)
AT (1) ATE164154T1 (cs)
AU (1) AU716256B2 (cs)
BG (1) BG62359B1 (cs)
CA (1) CA2181006C (cs)
CZ (1) CZ289617B6 (cs)
DE (1) DE69600189T2 (cs)
DK (1) DK0753512T3 (cs)
EA (1) EA000037B1 (cs)
ES (1) ES2113765T3 (cs)
HK (1) HK1010052A1 (cs)
HU (1) HU226691B1 (cs)
IL (1) IL118815A (cs)
MA (1) MA23936A1 (cs)
MX (1) MX9602767A (cs)
NO (1) NO306672B1 (cs)
NZ (1) NZ286951A (cs)
PL (1) PL191019B1 (cs)
RO (1) RO117376B1 (cs)
SG (1) SG43383A1 (cs)
SK (1) SK281254B6 (cs)
TR (1) TR199600579A2 (cs)
TW (1) TW419462B (cs)
UA (1) UA42749C2 (cs)
UY (1) UY24283A1 (cs)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5052729B2 (ja) * 2000-08-08 2012-10-17 第一三共株式会社 双環化合物の製造方法およびその中間体
US20070015780A1 (en) * 2003-03-10 2007-01-18 Picker Donald H Method of treating cancer with azaspirane compositions
CN104119321B (zh) * 2013-04-28 2017-09-08 齐鲁制药有限公司 二氢吲哚酮衍生物的二马来酸盐及其多晶型物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3211397A1 (de) * 1982-03-27 1983-11-10 Hoechst Ag, 6230 Frankfurt Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
US4430335A (en) * 1983-02-09 1984-02-07 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1-azaspiro[4,5]decanes and their analgesic compositions
US4963557A (en) * 1987-09-28 1990-10-16 Smithkline Beecham Corporation Immunomodulatory azaspiranes
US4853409A (en) * 1988-04-13 1989-08-01 Pfizer Inc. 3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
PT100566B (pt) * 1991-06-07 1999-06-30 Smithkline Beecham Corp Azaspiranos imunomoduladores, composicoes farmaceuticas que os contem, sua preparacao e seu uso
GB9122735D0 (en) * 1991-10-25 1991-12-11 Smithkline Beecham Corp Methods
GB9217116D0 (en) * 1992-08-13 1992-09-23 Smithkline Beecham Corp Methods
US5506232A (en) * 1994-03-28 1996-04-09 Boehringer Mannheim Italia S.P.A. 6,9-bis[(2-aminoethyl)amino]benzo[g]isoquinoline-5,10-dione and its dimaleate salt

Also Published As

Publication number Publication date
SK281254B6 (sk) 2001-01-18
EA199600048A2 (ru) 1996-12-30
BG62359B1 (bg) 1999-09-30
MX9602767A (es) 1998-01-31
CA2181006A1 (en) 1997-01-14
KR100404832B1 (ko) 2004-01-13
EP0753512A1 (en) 1997-01-15
BG100710A (bg) 1997-03-31
JPH09118618A (ja) 1997-05-06
DE69600189D1 (de) 1998-04-23
PL315191A1 (en) 1997-01-20
EA000037B1 (ru) 1998-02-26
CN1067378C (zh) 2001-06-20
NO962931D0 (no) 1996-07-12
PL191019B1 (pl) 2006-03-31
HU226691B1 (en) 2009-06-29
CN1140710A (zh) 1997-01-22
HUP9601918A2 (en) 1997-09-29
IL118815A (en) 2000-06-29
RO117376B1 (ro) 2002-02-28
ATE164154T1 (de) 1998-04-15
JP3949750B2 (ja) 2007-07-25
TW419462B (en) 2001-01-21
NO962931L (no) 1997-01-14
AU5945596A (en) 1997-01-23
AR003452A1 (es) 1998-08-05
HU9601918D0 (en) 1996-09-30
HUP9601918A3 (en) 1998-01-28
SK88696A3 (en) 1997-06-04
DK0753512T3 (da) 1998-10-19
SG43383A1 (en) 1997-10-17
CA2181006C (en) 2007-04-03
CZ203696A3 (en) 1997-03-12
ES2113765T3 (es) 1998-05-01
EP0753512B1 (en) 1998-03-18
EA199600048A3 (ru) 1997-03-31
NZ286951A (en) 1998-02-26
CZ289617B6 (cs) 2002-03-13
HK1010052A1 (en) 1999-06-11
IL118815A0 (en) 1996-10-31
TR199600579A2 (tr) 1997-01-21
AU716256B2 (en) 2000-02-24
DE69600189T2 (de) 1998-10-15
UY24283A1 (es) 2001-10-25
KR970069987A (ko) 1997-11-07
MA23936A1 (fr) 1997-04-01
UA42749C2 (uk) 2001-11-15

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