FI953784A7 - 3'-atsiridinoantrasykliinijohdannaiset - Google Patents

3'-atsiridinoantrasykliinijohdannaiset

Info

Publication number
FI953784A7
FI953784A7 FI953784A FI953784A FI953784A7 FI 953784 A7 FI953784 A7 FI 953784A7 FI 953784 A FI953784 A FI 953784A FI 953784 A FI953784 A FI 953784A FI 953784 A7 FI953784 A7 FI 953784A7
Authority
FI
Finland
Prior art keywords
aziridinoanthracycline
derivatives
aziridinoanthracycline derivatives
Prior art date
Application number
FI953784A
Other languages
English (en)
Swedish (sv)
Other versions
FI953784A0 (fi
FI108036B (fi
Inventor
Alberto Bargiotti
Michele Caruso
Maria Grandi
Marina Ripamonti
Antonino Suarato
Original Assignee
Pharmacia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Spa filed Critical Pharmacia Spa
Publication of FI953784A7 publication Critical patent/FI953784A7/fi
Publication of FI953784A0 publication Critical patent/FI953784A0/fi
Application granted granted Critical
Publication of FI108036B publication Critical patent/FI108036B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
FI953784A 1993-12-13 1995-08-09 Menetelmä antituumorisesti aktiivisten antrasykliiniglykosidien valmistamiseksi FI108036B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB939325417A GB9325417D0 (en) 1993-12-13 1993-12-13 3'- aziridino-anthracycline derivatives
GB9325417 1993-12-13
PCT/EP1994/003840 WO1995016695A2 (en) 1993-12-13 1994-11-21 3'-aziridino-anthracycline derivatives
EP9403840 1994-11-21

Publications (3)

Publication Number Publication Date
FI953784A7 true FI953784A7 (fi) 1995-08-09
FI953784A0 FI953784A0 (fi) 1995-08-09
FI108036B FI108036B (fi) 2001-11-15

Family

ID=10746494

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953784A FI108036B (fi) 1993-12-13 1995-08-09 Menetelmä antituumorisesti aktiivisten antrasykliiniglykosidien valmistamiseksi

Country Status (25)

Country Link
US (1) US5532218A (fi)
EP (1) EP0683788B1 (fi)
JP (1) JPH08506835A (fi)
KR (1) KR100352734B1 (fi)
CN (1) CN1039123C (fi)
AT (1) ATE157369T1 (fi)
AU (1) AU676625B2 (fi)
CA (1) CA2154890A1 (fi)
DE (1) DE69405214T2 (fi)
DK (1) DK0683788T3 (fi)
ES (1) ES2107294T3 (fi)
FI (1) FI108036B (fi)
GB (1) GB9325417D0 (fi)
GR (1) GR3025266T3 (fi)
HU (1) HU217630B (fi)
IL (1) IL111725A (fi)
MY (1) MY117086A (fi)
NO (1) NO304951B1 (fi)
NZ (1) NZ276401A (fi)
PL (1) PL178806B1 (fi)
RU (1) RU2149163C1 (fi)
TW (1) TW336235B (fi)
UA (1) UA43839C2 (fi)
WO (1) WO1995016695A2 (fi)
ZA (1) ZA949701B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9808027D0 (en) * 1998-04-15 1998-06-17 Pharmacia & Upjohn Spa 13-dihydro-3' aziridino anthracyclines
GB9904386D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB9904387D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB0006601D0 (en) * 2000-03-17 2000-05-10 Pharmacia & Upjohn Spa Crystalline alkycycline derivative
GB0117403D0 (en) * 2001-07-17 2001-09-05 Pharmacia & Upjohn Spa Solvent-free crystalline anthracycline derivatives
CN101237771B (zh) * 2005-05-12 2013-03-20 俄亥俄州立大学研究基金会 多重耐药抗癌药蒽环类
EP2277884B1 (en) * 2008-04-11 2017-08-23 Tianjin Hemay Oncology Pharmaceutical Co., Ltd Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
CN101912600B (zh) * 2010-01-11 2014-01-29 杨国汉 改善胰岛素在溶液中稳定性的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54141759A (en) * 1978-04-24 1979-11-05 Microbial Chem Res Found Novel anthracycline derivative
SU1450749A3 (ru) * 1983-07-18 1989-01-07 Сри Интернэшнл (Фирма) Способ получени производных морфолинилдоксорубицина
FR2591599B1 (fr) * 1985-12-17 1988-08-05 Hoechst Lab Nouvelles anthracyclines et medicaments les contenant
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
GB9114549D0 (en) * 1991-07-05 1991-08-21 Erba Carlo Spa Mono and bis alkylamino-anthracyclines
US5413992A (en) * 1992-07-31 1995-05-09 The Scripps Research Institute Daunomycin derivative with reduced cytotoxicity toward normal cells

Also Published As

Publication number Publication date
DK0683788T3 (da) 1997-10-27
IL111725A0 (en) 1995-01-24
ATE157369T1 (de) 1997-09-15
AU676625B2 (en) 1997-03-13
WO1995016695A3 (en) 1995-07-13
IL111725A (en) 1998-07-15
TW336235B (en) 1998-07-11
US5532218A (en) 1996-07-02
NO953163D0 (no) 1995-08-11
NO953163L (no) 1995-10-02
NZ276401A (en) 1997-10-24
HK1011692A1 (en) 1999-07-16
GB9325417D0 (en) 1994-02-16
CN1039123C (zh) 1998-07-15
KR960701074A (ko) 1996-02-24
MY117086A (en) 2004-05-31
KR100352734B1 (ko) 2003-02-17
PL178806B1 (pl) 2000-06-30
DE69405214D1 (de) 1997-10-02
JPH08506835A (ja) 1996-07-23
DE69405214T2 (de) 1998-01-29
AU1066095A (en) 1995-07-03
ZA949701B (en) 1995-12-12
GR3025266T3 (en) 1998-02-27
EP0683788A1 (en) 1995-11-29
CA2154890A1 (en) 1995-06-22
CN1117734A (zh) 1996-02-28
UA43839C2 (uk) 2002-01-15
EP0683788B1 (en) 1997-08-27
FI953784A0 (fi) 1995-08-09
NO304951B1 (no) 1999-03-08
RU2149163C1 (ru) 2000-05-20
HU9502662D0 (en) 1995-11-28
WO1995016695A2 (en) 1995-06-22
ES2107294T3 (es) 1997-11-16
FI108036B (fi) 2001-11-15
PL310177A1 (en) 1995-11-27
HUT73172A (en) 1996-06-28
HU217630B (hu) 2000-03-28

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: PHARMACIA & UPJOHN S.P.A.

MA Patent expired