NO304951B1 - Aziridinoantracyklinderivater - Google Patents

Aziridinoantracyklinderivater

Info

Publication number
NO304951B1
NO304951B1 NO953163A NO953163A NO304951B1 NO 304951 B1 NO304951 B1 NO 304951B1 NO 953163 A NO953163 A NO 953163A NO 953163 A NO953163 A NO 953163A NO 304951 B1 NO304951 B1 NO 304951B1
Authority
NO
Norway
Prior art keywords
group
hydrogen
linear
alkyl
formula
Prior art date
Application number
NO953163A
Other languages
English (en)
Other versions
NO953163D0 (no
NO953163L (no
Inventor
Alberto Bargiotti
Michele Caruso
Maria Grandi
Marina Ripamonti
Antonino Suarato
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Publication of NO953163D0 publication Critical patent/NO953163D0/no
Publication of NO953163L publication Critical patent/NO953163L/no
Publication of NO304951B1 publication Critical patent/NO304951B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
NO953163A 1993-12-13 1995-08-11 Aziridinoantracyklinderivater NO304951B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939325417A GB9325417D0 (en) 1993-12-13 1993-12-13 3'- aziridino-anthracycline derivatives
PCT/EP1994/003840 WO1995016695A2 (en) 1993-12-13 1994-11-21 3'-aziridino-anthracycline derivatives

Publications (3)

Publication Number Publication Date
NO953163D0 NO953163D0 (no) 1995-08-11
NO953163L NO953163L (no) 1995-10-02
NO304951B1 true NO304951B1 (no) 1999-03-08

Family

ID=10746494

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953163A NO304951B1 (no) 1993-12-13 1995-08-11 Aziridinoantracyklinderivater

Country Status (26)

Country Link
US (1) US5532218A (no)
EP (1) EP0683788B1 (no)
JP (1) JPH08506835A (no)
KR (1) KR100352734B1 (no)
CN (1) CN1039123C (no)
AT (1) ATE157369T1 (no)
AU (1) AU676625B2 (no)
CA (1) CA2154890A1 (no)
DE (1) DE69405214T2 (no)
DK (1) DK0683788T3 (no)
ES (1) ES2107294T3 (no)
FI (1) FI108036B (no)
GB (1) GB9325417D0 (no)
GR (1) GR3025266T3 (no)
HK (1) HK1011692A1 (no)
HU (1) HU217630B (no)
IL (1) IL111725A (no)
MY (1) MY117086A (no)
NO (1) NO304951B1 (no)
NZ (1) NZ276401A (no)
PL (1) PL178806B1 (no)
RU (1) RU2149163C1 (no)
TW (1) TW336235B (no)
UA (1) UA43839C2 (no)
WO (1) WO1995016695A2 (no)
ZA (1) ZA949701B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948896A (en) * 1997-08-13 1999-09-07 Gem Pharmaceuticals Processes for preparing 13-deoxy anthracycline derivatives
US5942605A (en) * 1998-03-03 1999-08-24 Gem Pharmaceuticals, Inc. 5-imino-13-deoxy anthracycline derivatives, their uses, and processes for preparing them
GB9806324D0 (en) * 1998-03-24 1998-05-20 Pharmacia & Upjohn Spa Antitumour synergetic composition
GB9808027D0 (en) * 1998-04-15 1998-06-17 Pharmacia & Upjohn Spa 13-dihydro-3' aziridino anthracyclines
GB9904387D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB9904386D0 (en) * 1999-02-25 1999-04-21 Pharmacia & Upjohn Spa Antitumour synergistic composition
GB0006601D0 (en) * 2000-03-17 2000-05-10 Pharmacia & Upjohn Spa Crystalline alkycycline derivative
GB0117403D0 (en) * 2001-07-17 2001-09-05 Pharmacia & Upjohn Spa Solvent-free crystalline anthracycline derivatives
US7737123B2 (en) * 2005-05-12 2010-06-15 The Ohio State University Research Foundation Multidrug resistant anticancer anthracyclines
CA2721140C (en) * 2008-04-11 2016-02-09 Tianjin Hemay Bio-Tech Co. Ltd. Tetracyclic anthraquinone antibiotic derivatives with high activity, process for preparing the same and use thereof
CN101912600B (zh) * 2010-01-11 2014-01-29 杨国汉 改善胰岛素在溶液中稳定性的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54141759A (en) * 1978-04-24 1979-11-05 Microbial Chem Res Found Novel anthracycline derivative
GB8614323D0 (en) * 1986-06-12 1986-07-16 Erba Farmitalia Anthracyclines
US5413992A (en) * 1992-07-31 1995-05-09 The Scripps Research Institute Daunomycin derivative with reduced cytotoxicity toward normal cells

Also Published As

Publication number Publication date
CN1039123C (zh) 1998-07-15
JPH08506835A (ja) 1996-07-23
PL178806B1 (pl) 2000-06-30
DE69405214D1 (de) 1997-10-02
IL111725A0 (en) 1995-01-24
FI953784A (fi) 1995-08-09
FI953784A0 (fi) 1995-08-09
HU217630B (hu) 2000-03-28
UA43839C2 (uk) 2002-01-15
FI108036B (fi) 2001-11-15
GR3025266T3 (en) 1998-02-27
WO1995016695A2 (en) 1995-06-22
DK0683788T3 (da) 1997-10-27
NO953163D0 (no) 1995-08-11
HUT73172A (en) 1996-06-28
TW336235B (en) 1998-07-11
ES2107294T3 (es) 1997-11-16
AU676625B2 (en) 1997-03-13
US5532218A (en) 1996-07-02
AU1066095A (en) 1995-07-03
KR960701074A (ko) 1996-02-24
CA2154890A1 (en) 1995-06-22
HU9502662D0 (en) 1995-11-28
KR100352734B1 (ko) 2003-02-17
RU2149163C1 (ru) 2000-05-20
GB9325417D0 (en) 1994-02-16
MY117086A (en) 2004-05-31
CN1117734A (zh) 1996-02-28
WO1995016695A3 (en) 1995-07-13
NO953163L (no) 1995-10-02
ATE157369T1 (de) 1997-09-15
IL111725A (en) 1998-07-15
PL310177A1 (en) 1995-11-27
EP0683788B1 (en) 1997-08-27
EP0683788A1 (en) 1995-11-29
HK1011692A1 (en) 1999-07-16
NZ276401A (en) 1997-10-24
DE69405214T2 (de) 1998-01-29
ZA949701B (en) 1995-12-12

Similar Documents

Publication Publication Date Title
HK1013289A1 (en) Naphthalene derivatives as prostaglandin 12 agonists
ES468119A1 (es) Un procedimiento para la preparacion de triazinas
NO304951B1 (no) Aziridinoantracyklinderivater
CA2085345A1 (en) Pyrimidine nucleoside derivatives
HUP0100184A2 (hu) Szubsztituált 2-(benzil-amino)-2-fenil-acetamid-vegyületek és ezeket tartalmazó gyógyszerkészítmények
ES8706139A1 (es) Procedimiento para la fabricacion de nuevos derivados de la cumarina
GR3029471T3 (en) 2-substituted quinolines for treating leishmanioses.
ES467069A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1-3-bencenodimetanol
TW350838B (en) Quinoline derivatives
ES2188515T3 (es) Derivados de 22r-hidroxicolesta-8,14-dieno con actividad inhibidora de la meiosis.
ES472085A1 (es) Un procedimiento para la preparacion de una composicion te- rapeutica para el tratamiento de enfermedades alergicas.
PT1189908E (pt) Alcaloides de indolocarbazole de um actinomiceto marinho
ES465406A1 (es) Un procedimiento para la preparacion de nuevos derivados de 5-fluorouracilo.
ES447751A1 (es) Procedimiento para preparar derivados de imidazolilquinazo- lina.
TR199701289T2 (xx) Karbapenemlerin esterleri
GB9918079D0 (en) New cytotoxic pyrido (2,3,4-kl) acridine derivatives
TW333554B (en) Benzidine derivative and electrophotosensitive material using the same
ATE266648T1 (de) Heterocyclische anthracyclinonderivate

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees