NO305434B1 - Terapeutisk anvendbare tetrahydroisokinolinderivater, farmas°ytiske blandinger eller preparater og anvendelse derav - Google Patents
Terapeutisk anvendbare tetrahydroisokinolinderivater, farmas°ytiske blandinger eller preparater og anvendelse deravInfo
- Publication number
- NO305434B1 NO305434B1 NO955234A NO955234A NO305434B1 NO 305434 B1 NO305434 B1 NO 305434B1 NO 955234 A NO955234 A NO 955234A NO 955234 A NO955234 A NO 955234A NO 305434 B1 NO305434 B1 NO 305434B1
- Authority
- NO
- Norway
- Prior art keywords
- optionally substituted
- pct
- alkyl
- alkoxy
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/08—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939312807A GB9312807D0 (en) | 1993-06-22 | 1993-06-22 | Therapeutic agents |
| GB939312808A GB9312808D0 (en) | 1993-06-22 | 1993-06-22 | Therapeutic agents |
| PCT/EP1994/001926 WO1995000489A1 (en) | 1993-06-22 | 1994-06-10 | Isoquinoline derivatives as therapeutic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO955234D0 NO955234D0 (no) | 1995-12-21 |
| NO955234L NO955234L (no) | 1996-02-21 |
| NO305434B1 true NO305434B1 (no) | 1999-05-31 |
Family
ID=26303101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO955234A NO305434B1 (no) | 1993-06-22 | 1995-12-21 | Terapeutisk anvendbare tetrahydroisokinolinderivater, farmas°ytiske blandinger eller preparater og anvendelse derav |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5807868A (pl) |
| EP (1) | EP0707570B1 (pl) |
| JP (1) | JPH08511549A (pl) |
| CN (1) | CN1046713C (pl) |
| AT (1) | ATE165823T1 (pl) |
| AU (1) | AU679765B2 (pl) |
| BG (1) | BG62403B1 (pl) |
| BR (1) | BR9406897A (pl) |
| CA (1) | CA2165823A1 (pl) |
| CZ (1) | CZ290661B6 (pl) |
| DE (1) | DE69410093T2 (pl) |
| DK (1) | DK0707570T3 (pl) |
| ES (1) | ES2116601T3 (pl) |
| FI (1) | FI956150A0 (pl) |
| HU (1) | HU211157A9 (pl) |
| LV (1) | LV11323A (pl) |
| MY (1) | MY111699A (pl) |
| NO (1) | NO305434B1 (pl) |
| NZ (1) | NZ268587A (pl) |
| PL (1) | PL177947B1 (pl) |
| RO (1) | RO117377B1 (pl) |
| RU (1) | RU2135472C1 (pl) |
| SK (1) | SK280108B6 (pl) |
| TW (1) | TW353658B (pl) |
| UA (1) | UA42730C2 (pl) |
| WO (1) | WO1995000489A1 (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9524681D0 (en) | 1995-12-02 | 1996-01-31 | Knoll Ag | Chemical process |
| CN1268942A (zh) | 1997-06-27 | 2000-10-04 | 藤泽药品工业株式会社 | 磺酰胺化合物及其药物用途 |
| WO1999016752A1 (en) * | 1997-09-30 | 1999-04-08 | Molecular Designs International, Inc. | β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF USING |
| MXPA02008797A (es) * | 2000-03-14 | 2005-09-08 | Actelion Pharmaceuticals Ltd | Derivados de 1,2,3,4-tetrahidroisoquinolina. |
| US6593341B2 (en) | 2001-03-29 | 2003-07-15 | Molecular Design International, Inc. | β3-adrenoreceptor agonists, agonist compositions and methods of making and using the same |
| US6596734B1 (en) | 2002-10-11 | 2003-07-22 | Molecular Design International, Inc. | Tetrahydroisoquinoline compounds for use as β3-adrenoreceptor agonists |
| CA2585698A1 (en) * | 2004-11-04 | 2006-05-18 | Peter Xianqi Wang | Opiate intermediates and methods of synthesis |
| US7511060B2 (en) | 2005-10-21 | 2009-03-31 | Mallinckrodt Inc. | Opiate intermediates and methods of synthesis |
| US7622586B2 (en) * | 2005-10-21 | 2009-11-24 | Mallinckrodt Inc. | Opiate intermediates and methods of synthesis |
| CN105585527B (zh) * | 2015-12-17 | 2018-06-26 | 浙江工业大学 | 2-(3,4-二氢异喹啉-1(2h)-亚基)乙腈类化合物及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR868733A (fr) * | 1939-10-14 | 1942-01-14 | Troponwerke Dinklage & Co | Procédé pour la fabrication des composés d'isoquinoleine |
| CH420086A (de) * | 1962-01-19 | 1966-09-15 | Hoffmann La Roche | Verfahren zur Herstellung von Tetrahydroisochinolin-Derivaten |
| JPS5734275B2 (pl) * | 1973-07-30 | 1982-07-22 | ||
| IL63918A0 (en) * | 1980-10-17 | 1981-12-31 | Pennwalt Corp | N-(amino(or hydroxy)phenethyl)-1,2,3,4-tetrahydroisoquinolines,their preparation and pharmaceutical compositions containing them |
| US4766131A (en) * | 1980-10-17 | 1988-08-23 | Pennwalt Corporation | 2-amino (or hydroxy) phenethyl-1,2,3,4-tetrahydroisoquinolines as analgesics |
| US4375471A (en) * | 1981-02-19 | 1983-03-01 | Hoechst-Roussel Pharmaceuticals Inc. | 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines |
| GB8501192D0 (en) * | 1985-01-17 | 1985-02-20 | Boots Co Plc | Therapeutic agents |
| GB8921304D0 (en) * | 1989-09-20 | 1989-11-08 | Wyeth John & Brother Ltd | New method of treatment and heterocyclic compounds used therein |
| JP2716548B2 (ja) * | 1989-11-01 | 1998-02-18 | 雅昭 廣部 | パーキンソニズム予防・治療剤 |
| GB9127306D0 (en) * | 1991-12-23 | 1992-02-19 | Boots Co Plc | Therapeutic agents |
-
1994
- 1994-06-10 ES ES94920931T patent/ES2116601T3/es not_active Expired - Lifetime
- 1994-06-10 BR BR9406897A patent/BR9406897A/pt not_active Application Discontinuation
- 1994-06-10 DK DK94920931T patent/DK0707570T3/da active
- 1994-06-10 AU AU71851/94A patent/AU679765B2/en not_active Ceased
- 1994-06-10 JP JP7502404A patent/JPH08511549A/ja not_active Ceased
- 1994-06-10 AT AT94920931T patent/ATE165823T1/de not_active IP Right Cessation
- 1994-06-10 NZ NZ268587A patent/NZ268587A/en unknown
- 1994-06-10 UA UA96010210A patent/UA42730C2/uk unknown
- 1994-06-10 DE DE69410093T patent/DE69410093T2/de not_active Expired - Fee Related
- 1994-06-10 CN CN94193000A patent/CN1046713C/zh not_active Expired - Fee Related
- 1994-06-10 CA CA002165823A patent/CA2165823A1/en not_active Abandoned
- 1994-06-10 PL PL94312251A patent/PL177947B1/pl unknown
- 1994-06-10 RO RO95-02230A patent/RO117377B1/ro unknown
- 1994-06-10 CZ CZ19953427A patent/CZ290661B6/cs not_active IP Right Cessation
- 1994-06-10 SK SK1604-95A patent/SK280108B6/sk unknown
- 1994-06-10 US US08/564,156 patent/US5807868A/en not_active Expired - Fee Related
- 1994-06-10 EP EP94920931A patent/EP0707570B1/en not_active Expired - Lifetime
- 1994-06-10 WO PCT/EP1994/001926 patent/WO1995000489A1/en active IP Right Grant
- 1994-06-10 RU RU96102846/04A patent/RU2135472C1/ru not_active IP Right Cessation
- 1994-06-16 MY MYPI94001537A patent/MY111699A/en unknown
- 1994-12-21 TW TW083112011A patent/TW353658B/zh active
-
1995
- 1995-06-30 HU HU95P/P00685P patent/HU211157A9/hu unknown
- 1995-12-06 BG BG100195A patent/BG62403B1/bg unknown
- 1995-12-20 FI FI956150A patent/FI956150A0/fi unknown
- 1995-12-21 NO NO955234A patent/NO305434B1/no unknown
-
1996
- 1996-01-22 LV LV960014A patent/LV11323A/xx unknown
-
1997
- 1997-03-27 US US08/826,012 patent/US5804586A/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GEP19970661B (en) | Process for preparing arylcyclobutyl alkylamine derivatives | |
| FI943018A0 (fi) | Terapeuttisia aineita | |
| DK0618898T3 (da) | Amidinoderivater | |
| ES2128791T3 (es) | Derivados espirocetales, composiciones que los contienen y su uso como agentes terapeuticos. | |
| ES2141957T3 (es) | Uso de raloxifeno y sus analogos para la produccion de un medicamento para el tratamiento de enfermedades virales. | |
| HUP0002272A2 (hu) | Piperazinszármazékok, eljárás előállításukra, e vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk | |
| NO305434B1 (no) | Terapeutisk anvendbare tetrahydroisokinolinderivater, farmas°ytiske blandinger eller preparater og anvendelse derav | |
| HUP0100184A2 (hu) | Szubsztituált 2-(benzil-amino)-2-fenil-acetamid-vegyületek és ezeket tartalmazó gyógyszerkészítmények | |
| FI934680A0 (fi) | Arylmorfolin, framstaellning och anvaending | |
| RU94046144A (ru) | Замещенные (арилалкиламинобензил) аминопропионамидные производные, их применение, способы их получения, фармкомпозиция | |
| ES8504103A1 (es) | Un procedimiento para preparar derivados de ciclobutano | |
| JO1815B1 (en) | Therapeutic agents | |
| FI950209A (fi) | Farmakologisesti aktiiviset alfa-(tertiaarinen-amino-metyyli)-bentseenimetanolijohdannaiset | |
| ATE206431T1 (de) | Antifungal fusacandine | |
| MY108027A (en) | Substitute tetrahydroisoquinolines and use as therepuetic agents | |
| ES2109512T3 (es) | Macrolactama (ciclamenol) antiinflamatoria. | |
| JO1758B1 (en) | Therapeutic agents | |
| ES2120039T3 (es) | Nuevos acildipeptidos heterociclicos, procedimientos de preparacion y composiciones farmaceuticas que los contienen. | |
| ES2119454T3 (es) | Derivados de pirrolidina para el tratamiento de los desordenes relacionados con la csk y la gastrina. | |
| RU94038051A (ru) | Гетероциклические производные, способ их получения, фармацевтическая композиция и способ лечения | |
| KR970704686A (ko) | 비시클로락탐 화합물, 그 용도 및 그 제조중간체(bicyclolactam compounds, use of the same and intermediate in the production of the same) | |
| ECSP972209A (es) | Nuevos compuestos, procedimientos para su preparacion, composiciones, farmaceuticas y su uso en terapia |