NO305165B1 - 1-Arylcykloalkylsulfider, -sulfoksyder og -sulfoner, farmas°ytiske preparater og anvendelse derav - Google Patents

1-Arylcykloalkylsulfider, -sulfoksyder og -sulfoner, farmas°ytiske preparater og anvendelse derav

Info

Publication number
NO305165B1
NO305165B1 NO954542A NO954542A NO305165B1 NO 305165 B1 NO305165 B1 NO 305165B1 NO 954542 A NO954542 A NO 954542A NO 954542 A NO954542 A NO 954542A NO 305165 B1 NO305165 B1 NO 305165B1
Authority
NO
Norway
Prior art keywords
pct
optionally substituted
alkyl
sec
arylcycloalkyl
Prior art date
Application number
NO954542A
Other languages
English (en)
Norwegian (no)
Other versions
NO954542L (no
NO954542D0 (no
Inventor
Paul John Harris
David John Heal
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of NO954542D0 publication Critical patent/NO954542D0/no
Publication of NO954542L publication Critical patent/NO954542L/no
Publication of NO305165B1 publication Critical patent/NO305165B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/24Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/25Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/26Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO954542A 1993-05-12 1995-11-10 1-Arylcykloalkylsulfider, -sulfoksyder og -sulfoner, farmas°ytiske preparater og anvendelse derav NO305165B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939309749A GB9309749D0 (en) 1993-05-12 1993-05-12 Therapeutic agents
PCT/EP1994/001494 WO1994026704A1 (en) 1993-05-12 1994-05-07 1-arylcycloalkyl sulphides, sulphoxides and sulphones for the treatment of depression, anxiety and parkinson's disease

Publications (3)

Publication Number Publication Date
NO954542D0 NO954542D0 (no) 1995-11-10
NO954542L NO954542L (no) 1996-01-10
NO305165B1 true NO305165B1 (no) 1999-04-12

Family

ID=10735317

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954542A NO305165B1 (no) 1993-05-12 1995-11-10 1-Arylcykloalkylsulfider, -sulfoksyder og -sulfoner, farmas°ytiske preparater og anvendelse derav

Country Status (29)

Country Link
US (1) US5652271A (zh)
EP (1) EP0715620B1 (zh)
JP (2) JP3606326B2 (zh)
KR (1) KR100295264B1 (zh)
AT (1) ATE172719T1 (zh)
AU (1) AU681669B2 (zh)
BG (1) BG61913B1 (zh)
BR (2) BR9406577A (zh)
CZ (1) CZ290711B6 (zh)
DE (1) DE69414264T2 (zh)
DK (1) DK0715620T3 (zh)
ES (1) ES2124411T3 (zh)
FI (1) FI955429A (zh)
GB (1) GB9309749D0 (zh)
HU (1) HU211124A9 (zh)
IL (1) IL109635A (zh)
LV (1) LV11320A (zh)
MY (1) MY110773A (zh)
NO (1) NO305165B1 (zh)
NZ (1) NZ266776A (zh)
PH (1) PH30418A (zh)
PL (1) PL176400B1 (zh)
RO (1) RO115519B1 (zh)
RU (1) RU2135467C1 (zh)
SK (1) SK281257B6 (zh)
TW (1) TW318833B (zh)
UA (1) UA42722C2 (zh)
WO (1) WO1994026704A1 (zh)
ZA (1) ZA943241B (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518988A1 (de) * 1995-05-29 1996-12-05 Basf Ag Verwendung arylsubstituierter Cyclobutylalkylamine zur Behandlung der Fettleibigkeit
GB9524681D0 (en) 1995-12-02 1996-01-31 Knoll Ag Chemical process
GB9915617D0 (en) * 1999-07-05 1999-09-01 Knoll Ag Therapeutic agents
US20030224045A1 (en) * 2002-05-29 2003-12-04 Chien-Hsuan Han Combination immediate release sustained release levodopa/carbidopa dosage forms
US20060013875A1 (en) * 2002-05-29 2006-01-19 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
US20040166159A1 (en) * 2002-05-29 2004-08-26 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
US7094427B2 (en) * 2002-05-29 2006-08-22 Impax Laboratories, Inc. Combination immediate release controlled release levodopa/carbidopa dosage forms
MX2008013728A (es) * 2006-04-26 2009-01-07 Toyama Chemical Co Ltd Inductor de neurogenesis o agente terapeutico de neuropatia que abarca el derivado del eter alkilico o sal del mismo.
EP3054929B1 (en) 2013-10-07 2020-08-05 Impax Laboratories, LLC Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
IE56000B1 (en) * 1982-09-30 1991-03-13 Boots Co Plc 1-arylcyclobutylalkylamine compounds
GB8501192D0 (en) * 1985-01-17 1985-02-20 Boots Co Plc Therapeutic agents
GB8704777D0 (en) * 1987-02-28 1987-04-01 Boots Co Plc Medical treatment

Also Published As

Publication number Publication date
ES2124411T3 (es) 1999-02-01
JPH08510222A (ja) 1996-10-29
LV11320A (lv) 1996-06-20
PL311628A1 (en) 1996-03-04
AU6843394A (en) 1994-12-12
CZ290711B6 (cs) 2002-09-11
IL109635A0 (en) 1994-11-11
PL176400B1 (pl) 1999-05-31
WO1994026704A1 (en) 1994-11-24
GB9309749D0 (en) 1993-06-23
NO954542L (no) 1996-01-10
ZA943241B (en) 1994-11-14
RO115519B1 (ro) 2000-03-30
SK140795A3 (en) 1996-09-04
UA42722C2 (uk) 2001-11-15
FI955429A (fi) 1996-01-03
NZ266776A (en) 1998-02-26
FI955429A0 (fi) 1995-11-10
BR1100306A (pt) 2002-04-02
BG61913B1 (bg) 1998-09-30
DE69414264D1 (de) 1998-12-03
JP2004331669A (ja) 2004-11-25
DE69414264T2 (de) 1999-03-25
RU2135467C1 (ru) 1999-08-27
JP3606326B2 (ja) 2005-01-05
AU681669B2 (en) 1997-09-04
EP0715620A1 (en) 1996-06-12
IL109635A (en) 1998-03-10
MY110773A (en) 1999-03-31
EP0715620B1 (en) 1998-10-28
SK281257B6 (sk) 2001-01-18
TW318833B (zh) 1997-11-01
BR9406577A (pt) 1996-01-30
BG100127A (bg) 1996-07-31
HU211124A9 (en) 1995-10-30
NO954542D0 (no) 1995-11-10
PH30418A (en) 1997-05-09
CZ293695A3 (en) 1996-06-12
KR100295264B1 (ko) 2001-09-17
US5652271A (en) 1997-07-29
ATE172719T1 (de) 1998-11-15
DK0715620T3 (da) 1999-07-05

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