ES2116880A1 - Farmacos y composiciones farmaceuticas para su uso en el tratamiento de enfermedades. - Google Patents
Farmacos y composiciones farmaceuticas para su uso en el tratamiento de enfermedades.Info
- Publication number
- ES2116880A1 ES2116880A1 ES09500774A ES9500774A ES2116880A1 ES 2116880 A1 ES2116880 A1 ES 2116880A1 ES 09500774 A ES09500774 A ES 09500774A ES 9500774 A ES9500774 A ES 9500774A ES 2116880 A1 ES2116880 A1 ES 2116880A1
- Authority
- ES
- Spain
- Prior art keywords
- psychosis
- parkinson
- disease
- alkyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
FARMACOS Y COMPOSICIONES FARMACEUTICAS PARA SU USO EN EL TRATAMIENTO DE ENFERMEDADES. EL USO DE COMPUESTOS PARA LA PREPARACION DE UN MEDICAMENTO PARA TRATAR DISQUINESIAS INDUCIDAS POR FARMACOS, ENFERMEDAD DE PARKINSON, PSICOSIS DOPAMINOMIMETICAS EN LA ENFERMEDAD DE PARKINSON, Y PSICOSIS, EN EL QUE UNA CANTIDAD TERAPEUTICAMENTE EFICAZ DE UN COMPUESTO DE FORMULA I O SALES Y METABOLITOS FARMACEUTICAMENTE ACEPTABLES DEL MISMO, EN LA QUE N ES UN NUMERO ENTERO DE 1 A 6; Y R REPRESENTA H, HALOGENO, ALQUILO DE 1 A 4, UN GRUPO HETEROARILO, SULFO, SULFAMOILO N-SUSTITUIDO O N,N-DISUSTITUIDO, NITRO, HIDROXI, OXO, ALCOXI DE 1 A 4, CIANO, ALQUILCARBOXILATO DE 1 A 4, UN GRUPO ARILO O ARILO SUSTITUIDO, O UN GRUPO AMINO O AMINO SUSTITUIDO DE FORMULA EN LA QUE R1, Y R2, QUE PUEDEN SER IGUALES O DIFERENTES, REPRESENTAN H, ALQUILO, ARILO, ALQUILCARBONILO, ARILCARBONILO, ALQUILSULFONILO O ARILSULFONILO, CONTENIENDO LOS FRAGMENTOS ALQUILO DE ESTOS GRUPOS DE 1 A 4 ATOMOS DE CARBONO, ES ADMINISTRADA JUNTO CON UN DILUYENTE O VEHICULO ACEPTABLE FARMACEUTICAMENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9408084A GB9408084D0 (en) | 1994-04-23 | 1994-04-23 | Medical treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2116880A1 true ES2116880A1 (es) | 1998-07-16 |
ES2116880B1 ES2116880B1 (es) | 1999-08-01 |
Family
ID=10754011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09500774A Expired - Fee Related ES2116880B1 (es) | 1994-04-23 | 1995-04-21 | Farmacos y composiciones farmaceuticas para su uso en el tratamiento de enfermedades. |
Country Status (5)
Country | Link |
---|---|
AU (1) | AU2137595A (es) |
ES (1) | ES2116880B1 (es) |
GB (1) | GB9408084D0 (es) |
WO (1) | WO1995028933A1 (es) |
ZA (1) | ZA953237B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5656762A (en) * | 1990-12-28 | 1997-08-12 | Neurogen Corporation | 4-piperidino-and piperazinomethyl-2-phenylimidazole derivatives, dopamine receptor subtype specific ligands |
US6166205A (en) * | 1998-09-02 | 2000-12-26 | Neurogen Corporation | 2-Aryl-4-(1-[4-heteroaryl]piperazin-1-yl)methylimidazoles: dopamine . D.sub4 receptor subtype ligands |
HN1999000146A (es) | 1998-09-21 | 2000-11-11 | Pfizer Prod Inc | Agentes farmaceuticos para el tratamiento de la enfermedad de parkinson, adhd y microadenomas. |
GB0027020D0 (en) | 2000-11-03 | 2000-12-20 | Univ Manchester | Treatment of movement disorders |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0497658A1 (fr) * | 1991-01-25 | 1992-08-05 | Laboratorios Del Dr. Esteve, S.A. | Utilisation de dérivés 1-H-azole-(omega-(4-(2-pyrimidinyl)-1-pipérazinyl)-alkyl) pour la préparation de médicaments destinés au traitement des troubles des fonctions cognitives |
-
1994
- 1994-04-23 GB GB9408084A patent/GB9408084D0/en active Pending
-
1995
- 1995-03-30 WO PCT/EP1995/001195 patent/WO1995028933A1/en active Application Filing
- 1995-03-30 AU AU21375/95A patent/AU2137595A/en not_active Abandoned
- 1995-04-21 ZA ZA953237A patent/ZA953237B/xx unknown
- 1995-04-21 ES ES09500774A patent/ES2116880B1/es not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0497658A1 (fr) * | 1991-01-25 | 1992-08-05 | Laboratorios Del Dr. Esteve, S.A. | Utilisation de dérivés 1-H-azole-(omega-(4-(2-pyrimidinyl)-1-pipérazinyl)-alkyl) pour la préparation de médicaments destinés au traitement des troubles des fonctions cognitives |
Non-Patent Citations (4)
Title |
---|
AHLENIUS, S. Antipsychotic-like properties of the 5-HT1A Agonist 8-OH-DPAT in the rat. Pharmacology & Toxycology. 1989, Vol. 64, pßginas 3-5 * Todo el documento * * |
HAJ-DAHMANE et al. Interactions of lesopitron (E-4424) with central 5-HT1A receptors: in vitro and in vivo studies in the rat. European J. of Pharmacology. 1994, Vol. 255, n‘ 1-3, pßginas 185-196 * Todo el documento * * |
INVERNIZZI et al. 8-Hidroxy-2-(di-N-propylamino) tetralin, a selective serotonin 1A receptor agonist, blocks haloperidol-induced cßtalepsy by an action on raphe nuclei medianus and dorsalis. Neuropharmacology. 1988, Vol. 27, N‘ 5, pßginas 515-518 * Todo el documento * * |
WOLTERS, E.C. et al. Clozapine in the treatment of parkinsonian patients with dopaminomimetic psychosis. Neurology. 1990, Vol. 40, n‘ 5, pßginas 832-834 * Todo el documento * * |
Also Published As
Publication number | Publication date |
---|---|
GB9408084D0 (en) | 1994-06-15 |
ES2116880B1 (es) | 1999-08-01 |
AU2137595A (en) | 1995-11-16 |
ZA953237B (en) | 1995-12-28 |
WO1995028933A1 (en) | 1995-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC2A | Transfer of patent |
Owner name: LABORATORIOS DEL DR. ESTEVE, S.A. |
|
EC2A | Search report published |
Date of ref document: 19980716 Kind code of ref document: A1 Effective date: 19980716 |
|
FD1A | Patent lapsed |
Effective date: 20020401 |