NO304944B1 - 7-isoindolinyl-kinolon- og -naftyridon-derivater med antibakteriell virkning - Google Patents

7-isoindolinyl-kinolon- og -naftyridon-derivater med antibakteriell virkning

Info

Publication number
NO304944B1
NO304944B1 NO933132A NO933132A NO304944B1 NO 304944 B1 NO304944 B1 NO 304944B1 NO 933132 A NO933132 A NO 933132A NO 933132 A NO933132 A NO 933132A NO 304944 B1 NO304944 B1 NO 304944B1
Authority
NO
Norway
Prior art keywords
quinolone
isoindolinyl
antibacterial activity
naphthyridone derivatives
naphthyridone
Prior art date
Application number
NO933132A
Other languages
English (en)
Norwegian (no)
Other versions
NO933132L (no
NO933132D0 (no
Inventor
Thomas Philipps
Stephan Bartel
Andreas Krebs
Uwe Petersen
Thomas Schenke
Klaus-Dieter Bremm
Rainer Endermann
Karl Georg Metzger
Burkhard Mielke
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO933132D0 publication Critical patent/NO933132D0/no
Publication of NO933132L publication Critical patent/NO933132L/no
Publication of NO304944B1 publication Critical patent/NO304944B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Quinoline Compounds (AREA)
  • Medicinal Preparation (AREA)
NO933132A 1992-09-15 1993-09-02 7-isoindolinyl-kinolon- og -naftyridon-derivater med antibakteriell virkning NO304944B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4230804A DE4230804A1 (de) 1992-09-15 1992-09-15 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate

Publications (3)

Publication Number Publication Date
NO933132D0 NO933132D0 (no) 1993-09-02
NO933132L NO933132L (no) 1994-03-16
NO304944B1 true NO304944B1 (no) 1999-03-08

Family

ID=6467987

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933132A NO304944B1 (no) 1992-09-15 1993-09-02 7-isoindolinyl-kinolon- og -naftyridon-derivater med antibakteriell virkning

Country Status (27)

Country Link
US (3) US5556979A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0588166B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP3199930B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100288522B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1044118C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE138920T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU668743B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (2) CA2105923C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CZ (1) CZ288493B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE4230804A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0588166T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2088618T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI934004L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3020484T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU222348B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ID (1) ID23959A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL106990A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MX (1) MX9305256A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY131373A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO304944B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (2) NZ248631A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (3) PL177155B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RU (1) RU2111964C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SK (1) SK282274B6 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW316899B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA35562C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA936759B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2112165C (en) * 1992-12-25 2003-04-08 Makoto Takemura Bicyclic amine derivatives
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
US5508424A (en) * 1993-03-26 1996-04-16 Ortho Pharmaceutical Corporation 4-arylisoindole analgesics
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
DE4418510A1 (de) * 1994-05-27 1995-11-30 Bayer Ag 1,9-überbrückte Thiazolol[3,4-a]chinolinderivate
DE4427530A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE4435479A1 (de) * 1994-10-04 1996-04-11 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
DE19500792A1 (de) * 1995-01-13 1996-07-18 Bayer Ag Chinolon- und Naphthyridoncarbonsäure-Derivate
ES2158963T3 (es) * 1995-02-09 2001-09-16 Bayer Ag Derivados de acidos 1,6-naftiridoncarboxilicos.
DE19506535A1 (de) * 1995-02-09 1996-08-14 Bayer Ag 1,6-Naphthyridoncarbonsäurederivate
DE19722812C2 (de) * 1997-05-30 2003-02-13 Bat Cigarettenfab Gmbh Ultraleicht-Koaxialcigarette mit mehrteiligem Filter
CO4970702A1 (es) 1997-09-15 2000-11-07 Procter & Gamble Quinolonas antimicrobianas, sus composiciones y sus usos
DE19751948A1 (de) 1997-11-24 1999-05-27 Bayer Ag Verfahren zur Herstellung von 8-Methoxy-Chinoloncarbonsäuren
CN1258531C (zh) * 1999-03-10 2006-06-07 第一制药株式会社 芳香族取代基取代的氨基甲基吡咯烷衍生物
US6667406B1 (en) * 1999-03-10 2003-12-23 Ortho-Mcneil Pharmaceutical, Inc. Methods for the synthesis of complex reduced isoindole, isooxyindole and isooxyquinoline libraries
AU2002230893B2 (en) 2000-12-14 2005-06-09 The Procter & Gamble Company Antimicrobial 2-pyridones, their compositions and uses
WO2002048138A1 (en) * 2000-12-14 2002-06-20 The Procter & Gamble Company Antimicrobial quinolones
ATE507219T1 (de) * 2006-03-28 2011-05-15 Warner Chilcott Co Llc Malatsalze und polymorphe von (3s,5s)-7-ä3-amino- 5-methyl-piperidinylü-1-cyclopropyl-1,4-dihydro 8-methoxy-4-oxo-3-chinolincarbonsäure
US7528264B2 (en) * 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
WO2007110835A2 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
RU2769675C2 (ru) * 2020-07-21 2022-04-04 Сергей Иванович Орлов Устройство передачи информации через барьер гальванической развязки

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
JPH0262875A (ja) * 1988-05-23 1990-03-02 Wakunaga Pharmaceut Co Ltd 新規イソインドリン誘導体
CA2030217A1 (en) * 1989-11-21 1991-05-22 Jun Imose Pyridone-carboxylic acid derivatives useful as veterinary medicines
CA2076982A1 (en) * 1990-12-27 1992-06-28 Akira Okura Pyridonecarboxylic acid derivatives
DE4120646A1 (de) * 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
US5468742A (en) * 1991-07-19 1995-11-21 Bayer Aktiengesellschaft 8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
DE4123918A1 (de) * 1991-07-19 1993-01-21 Bayer Ag 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
DE4408212A1 (de) * 1994-03-11 1995-09-14 Bayer Ag 5-Vinyl- und 5-Ethinyl-chinolon- und -naphthyridon-carbonsäuren

Also Published As

Publication number Publication date
ATE138920T1 (de) 1996-06-15
JPH06263755A (ja) 1994-09-20
EP0588166B1 (de) 1996-06-05
DK0588166T3 (da) 1996-10-07
EP0588166A2 (de) 1994-03-23
CZ190393A3 (en) 1994-04-13
NO933132L (no) 1994-03-16
US5556979A (en) 1996-09-17
TW316899B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-10-01
PL177155B1 (pl) 1999-09-30
CA2105923C (en) 2004-12-28
AU4492793A (en) 1994-03-24
FI934004A7 (fi) 1994-03-16
CN1087634A (zh) 1994-06-08
ID23959A (id) 1994-03-10
AU682134B2 (en) 1997-09-18
NO933132D0 (no) 1993-09-02
CN1044118C (zh) 1999-07-14
RU2111964C1 (ru) 1998-05-27
GR3020484T3 (en) 1996-10-31
IL106990A0 (en) 1993-12-28
US5739339A (en) 1998-04-14
FI934004A0 (fi) 1993-09-13
MY131373A (en) 2007-08-30
SK99093A3 (en) 1994-04-06
IL106990A (en) 1997-02-18
UA35562C2 (uk) 2001-04-16
CA2105923A1 (en) 1994-03-16
JP3199930B2 (ja) 2001-08-20
AU668743B2 (en) 1996-05-16
ZA936759B (en) 1994-04-11
EP0588166A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1994-04-27
NZ248631A (en) 1996-01-26
CA2469296A1 (en) 1994-03-16
ES2088618T3 (es) 1996-08-16
PL300385A1 (en) 1994-03-21
HU9302593D0 (en) 1993-11-29
HU222348B1 (hu) 2003-06-28
HUT65216A (en) 1994-05-02
KR100288522B1 (ko) 2001-05-02
SK282274B6 (sk) 2002-01-07
PL177140B1 (pl) 1999-09-30
NZ280374A (en) 1996-08-27
MX9305256A (es) 1995-01-31
US6018054A (en) 2000-01-25
DE59302809D1 (de) 1996-07-11
AU6205996A (en) 1996-10-24
DE4230804A1 (de) 1994-03-17
FI934004L (fi) 1994-03-16
PL177238B1 (pl) 1999-10-29
KR940007027A (ko) 1994-04-26
CZ288493B6 (en) 2001-06-13

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