NO302622B1 - Rekombinant vektor, vertsorganisme, fremgangsmåte for fremstilling av et fullengde PIA protein fra Neisseria gonorrhoeae - Google Patents

Rekombinant vektor, vertsorganisme, fremgangsmåte for fremstilling av et fullengde PIA protein fra Neisseria gonorrhoeae Download PDF

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Publication number
NO302622B1
NO302622B1 NO902251A NO902251A NO302622B1 NO 302622 B1 NO302622 B1 NO 302622B1 NO 902251 A NO902251 A NO 902251A NO 902251 A NO902251 A NO 902251A NO 302622 B1 NO302622 B1 NO 302622B1
Authority
NO
Norway
Prior art keywords
protein
pia
gene
plasmid
pib
Prior art date
Application number
NO902251A
Other languages
English (en)
Norwegian (no)
Other versions
NO902251L (no
NO902251D0 (no
Inventor
Nicholas H Carbonetti
P Frederick Sparling
Original Assignee
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ North Carolina filed Critical Univ North Carolina
Publication of NO902251D0 publication Critical patent/NO902251D0/no
Publication of NO902251L publication Critical patent/NO902251L/no
Publication of NO302622B1 publication Critical patent/NO302622B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO902251A 1987-11-24 1990-05-22 Rekombinant vektor, vertsorganisme, fremgangsmåte for fremstilling av et fullengde PIA protein fra Neisseria gonorrhoeae NO302622B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12472787A 1987-11-24 1987-11-24
US24275888A 1988-09-09 1988-09-09
PCT/US1988/004225 WO1989004873A1 (en) 1987-11-24 1988-11-23 Production of gonorrheal pi proteins and vaccines

Publications (3)

Publication Number Publication Date
NO902251D0 NO902251D0 (no) 1990-05-22
NO902251L NO902251L (no) 1990-07-18
NO302622B1 true NO302622B1 (no) 1998-03-30

Family

ID=26822891

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902251A NO302622B1 (no) 1987-11-24 1990-05-22 Rekombinant vektor, vertsorganisme, fremgangsmåte for fremstilling av et fullengde PIA protein fra Neisseria gonorrhoeae

Country Status (12)

Country Link
US (2) US5736361A (de)
EP (2) EP0395706B1 (de)
JP (2) JP2803058B2 (de)
KR (1) KR970011309B1 (de)
AT (1) ATE169958T1 (de)
AU (1) AU629807B2 (de)
CA (1) CA1340506C (de)
DE (1) DE3856240T2 (de)
DK (1) DK175831B1 (de)
FI (1) FI102189B (de)
NO (1) NO302622B1 (de)
WO (1) WO1989004873A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340506C (en) * 1987-11-24 1999-04-20 Nicholas H. Carbonetti Production of gonorrheal pi proteins and vaccines
US7118757B1 (en) * 1988-12-19 2006-10-10 Wyeth Holdings Corporation Meningococcal class 1 outer-membrane protein vaccine
ATE174625T1 (de) * 1991-03-14 1999-01-15 Imclone Systems Inc Rekombinante hybride porinepitope
WO1995004133A1 (en) * 1993-07-30 1995-02-09 The University Of North Carolina At Chapel Hill Production of gonorrheal pi proteins and vaccines in e. coli and salmonella
US7252828B2 (en) 1998-07-15 2007-08-07 The Brigham And Women's Hospital, Inc. Polysaccharide vaccine for staphylococcal infections
SK16022001A3 (sk) * 1999-05-13 2002-09-10 American Cyanamid Company Adjuvantné kombinované prostriedky
CA2386025A1 (en) * 1999-09-30 2001-04-05 Isis Innovation Limited Vaccine against neisseria infection
CA2875231A1 (en) * 2000-02-28 2001-09-07 Novartis Vaccines And Diagnostics S.R.L. Heterologous expression of neisserial proteins
CA2429000A1 (en) * 2000-11-10 2002-05-16 Wyeth Holdings Corporation Adjuvant combination formulations
CN100351260C (zh) 2002-11-12 2007-11-28 布赖汉姆妇女医院 葡萄球菌感染的多糖疫苗
EP1583517B1 (de) 2002-11-12 2019-06-12 The Brigham And Women's Hospital, Inc. Verfahren und produkte zur behandlung von infektionen mit staphylokokken
CN101001874B (zh) 2004-04-21 2012-12-19 布赖汉姆妇女医院 聚-n-乙酰葡萄糖胺(pnag/dpnag)结合肽及其应用方法
US7037698B2 (en) 2004-05-19 2006-05-02 Amano Enzyme Inc. Pyrroloquinoline quinone-dependent glucose dehydrogenase
ES2660594T3 (es) 2008-07-21 2018-03-23 The Brigham And Women's Hospital, Inc. Métodos y composiciones relacionados con oligosacáridos sintéticos de beta-1,6 glucosamina

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
US4203971A (en) * 1978-03-23 1980-05-20 Government Of The United States Neisseria gonorrhoeae vaccine
DE2814039C3 (de) * 1978-03-31 1981-02-19 Gesellschaft Fuer Biotechnologische Forschung Mbh (Gbf), 3300 Braunschweig Verfahren zur Herstellung von Hybrid-Bakterien
US4351761A (en) * 1978-05-15 1982-09-28 Research Corporation Purified antigen to test for Neisseria gonorrhoeae antibodies
US4220638A (en) * 1978-10-12 1980-09-02 Merck & Co., Inc. Antigenic complex from N. Gonorrhoeae
US4288557A (en) * 1978-10-12 1981-09-08 Merck & Co., Inc. Antigenic complex from N. gonorrhoeae
US4239749A (en) * 1979-09-27 1980-12-16 United States Of America Neisseria gonorrhoeae vaccine
FI63596C (fi) * 1981-10-16 1983-07-11 Orion Yhtymae Oy Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser
WO1983003354A1 (en) * 1982-03-30 1983-10-13 Us Army Neisseria gonorrhoeae vaccine
EP0178863A1 (de) * 1984-10-15 1986-04-23 Schering Corporation Expressionssysteme die sich der Bakteriophage-T7-Promotoren bedienen und Gensequenzen
US4681761A (en) * 1985-10-24 1987-07-21 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
CA1340506C (en) * 1987-11-24 1999-04-20 Nicholas H. Carbonetti Production of gonorrheal pi proteins and vaccines

Also Published As

Publication number Publication date
JPH10234388A (ja) 1998-09-08
KR890701750A (ko) 1989-12-21
US5736361A (en) 1998-04-07
NO902251L (no) 1990-07-18
DE3856240D1 (de) 1998-09-24
DK128490D0 (da) 1990-05-23
FI902569A0 (fi) 1990-05-23
AU629807B2 (en) 1992-10-15
DK128490A (da) 1990-07-06
JPH03502881A (ja) 1991-07-04
FI102189B1 (fi) 1998-10-30
FI102189B (fi) 1998-10-30
WO1989004873A1 (en) 1989-06-01
EP0395706A1 (de) 1990-11-07
DK175831B1 (da) 2005-03-14
DE3856240T2 (de) 1999-05-06
JP3388171B2 (ja) 2003-03-17
KR970011309B1 (ko) 1997-07-09
EP0395706B1 (de) 1998-08-19
AU2795989A (en) 1989-06-14
ATE169958T1 (de) 1998-09-15
NO902251D0 (no) 1990-05-22
US6068992A (en) 2000-05-30
JP2803058B2 (ja) 1998-09-24
EP0869133A1 (de) 1998-10-07
EP0395706A4 (en) 1991-11-13
CA1340506C (en) 1999-04-20

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