NO300254B1 - Fremgangsmåte for fremstilling av en vaksine mot humant respiratorisk syncytielt virus - Google Patents

Fremgangsmåte for fremstilling av en vaksine mot humant respiratorisk syncytielt virus Download PDF

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Publication number
NO300254B1
NO300254B1 NO902802A NO902802A NO300254B1 NO 300254 B1 NO300254 B1 NO 300254B1 NO 902802 A NO902802 A NO 902802A NO 902802 A NO902802 A NO 902802A NO 300254 B1 NO300254 B1 NO 300254B1
Authority
NO
Norway
Prior art keywords
plasmid
glycoprotein
fragment
cells
gene
Prior art date
Application number
NO902802A
Other languages
English (en)
Norwegian (no)
Other versions
NO902802D0 (no
NO902802L (no
Inventor
Michael Wathen
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO902802D0 publication Critical patent/NO902802D0/no
Publication of NO902802L publication Critical patent/NO902802L/no
Publication of NO300254B1 publication Critical patent/NO300254B1/no

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18522New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO902802A 1987-12-23 1990-06-22 Fremgangsmåte for fremstilling av en vaksine mot humant respiratorisk syncytielt virus NO300254B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13738787A 1987-12-23 1987-12-23
PCT/US1988/003784 WO1989005823A1 (en) 1987-12-23 1988-10-31 Chimeric glycoproteins containing immunogenic segments of the glycoproteins of human respiratory syncytial virus

Publications (3)

Publication Number Publication Date
NO902802D0 NO902802D0 (no) 1990-06-22
NO902802L NO902802L (no) 1990-06-22
NO300254B1 true NO300254B1 (no) 1997-05-05

Family

ID=22477194

Family Applications (1)

Application Number Title Priority Date Filing Date
NO902802A NO300254B1 (no) 1987-12-23 1990-06-22 Fremgangsmåte for fremstilling av en vaksine mot humant respiratorisk syncytielt virus

Country Status (14)

Country Link
US (2) US5194595A (fi)
EP (1) EP0396563B1 (fi)
JP (1) JP2716503B2 (fi)
KR (1) KR0137963B1 (fi)
AT (1) ATE85622T1 (fi)
AU (1) AU617739B2 (fi)
CA (1) CA1320163C (fi)
DE (1) DE3878468T2 (fi)
DK (1) DK173175B1 (fi)
FI (1) FI102382B (fi)
HK (1) HK166295A (fi)
MX (1) MX9203458A (fi)
NO (1) NO300254B1 (fi)
WO (1) WO1989005823A1 (fi)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8914968D0 (en) * 1989-06-29 1989-08-23 Connaught Lab Production of virus and purification of viral envelope proteins for vaccine use
US6004563A (en) * 1990-11-07 1999-12-21 American Home Products Corporation Feline vaccine compositions and method for preventing chlamydia infections or diseases using the same
US5824307A (en) 1991-12-23 1998-10-20 Medimmune, Inc. Human-murine chimeric antibodies against respiratory syncytial virus
GB9200117D0 (en) * 1992-01-06 1992-02-26 Connaught Lab Production of recombinant chimeric proteins for vaccine use
GB9207479D0 (en) * 1992-04-06 1992-05-20 Scotgen Ltd Novel antibodies for treatment and prevention of respiratory syncytial virus infection in animals and man
TW275632B (fi) * 1992-04-21 1996-05-11 American Cyanamid Co
KR960700271A (ko) * 1993-01-08 1996-01-19 로렌스 티. 웰츠 인간 호흡계 합포체 바이러스 fg 당단백질의 정제 및 리폴딩 방법(process for the purification and refolding of human respiratory syncytial virus fg glycoprotein)
US5723130A (en) * 1993-05-25 1998-03-03 Hancock; Gerald E. Adjuvants for vaccines against respiratory syncytial virus
US7300918B2 (en) 1994-01-14 2007-11-27 Matthias Rath Method of producing vaccines from protein signal oligopeptides
ES2344643T3 (es) * 1994-01-14 2010-09-02 Matthias Dr. Med. Rath Oligopeptidos de señal hidrofilicos y metodos de uso terapeutico.
FR2718452B1 (fr) * 1994-04-06 1996-06-28 Pf Medicament Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation.
US5716821A (en) * 1994-09-30 1998-02-10 Uab Research Foundation Prevention and treatment of respiratory tract disease
WO1996010400A1 (en) * 1994-09-30 1996-04-11 The Uab Research Foundation Gene therapy vectors and vaccines based on non-segmented negatives stranded rna viruses
FR2726472B1 (fr) * 1994-11-07 1997-01-31 Pf Medicament Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin
DE4442114A1 (de) * 1994-11-25 1996-05-30 Buna Sow Leuna Olefinverb Gmbh Nitrit-, phosphat- und aminfreies Kühl- und Wärmeübertragungsmittel
US5811524A (en) * 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US6015664A (en) * 1995-11-03 2000-01-18 Mcw Research Foundation Multiplex PCR assay using unequal primer concentrations to detect HPIV 1,2,3 and RSV A,B and influenza virus A, B
WO1998018819A1 (en) * 1996-10-29 1998-05-07 Smithkline Beecham Biologicals S.A. Purification of respiratory syncytial virus antigens
US6103466A (en) * 1997-07-14 2000-08-15 University Of Liege Double-muscling in mammals
EP1002068B1 (en) 1997-07-14 2009-09-09 University of Liège Mutations in the myostatin gene cause double-muscling in mammals
US20070067859A1 (en) * 1997-07-14 2007-03-22 Michel Georges Double-muscling in mammals
US6699478B1 (en) * 1997-09-19 2004-03-02 Wyeth Holdings Corporation Enhanced immune response to attachment (G) protein of Respiratory Syncytial Virus
GB9909077D0 (en) 1999-04-20 1999-06-16 Smithkline Beecham Biolog Novel compositions
ES2349348T3 (es) * 2000-01-27 2010-12-30 Medimmune, Llc Anticuerpos neutralizantes de rsv de ultra alta afinidad.
CA2401652A1 (en) * 2000-03-01 2001-09-07 Medimmune, Inc. High potency recombinant antibodies and method for producing them
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
AU2005247091B2 (en) * 2004-05-24 2010-08-12 Polymun Scientific Immunbiologische Forschung Gmbh Superloaded liposomes for drug delivery
CA2585891A1 (en) * 2004-10-29 2006-05-11 Medimmune, Inc. Methods of preventing and treating rsv infections and related conditions
EP1997830A1 (en) 2007-06-01 2008-12-03 AIMM Therapeutics B.V. RSV specific binding molecules and means for producing them
AU2008340949A1 (en) 2007-12-24 2009-07-02 Glaxosmithkline Biologicals S.A. Recombinant RSV antigens
KR20110045008A (ko) * 2008-07-18 2011-05-03 아이디 바이오메디컬 코포레이션 오브 퀘벡 키메라 호흡기 세포융합 바이러스 폴리펩티드 항원
US9492531B2 (en) 2009-06-24 2016-11-15 Glaxosmithkline Biologicals Sa Recombinant RSV vaccines
DK3178490T3 (da) 2009-07-15 2022-06-20 Glaxosmithkline Biologicals Sa RSV F-proteinsammensætninger og fremgangsmåder til fremstilling af disse
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
EP3656396A1 (en) 2012-08-01 2020-05-27 Bavarian Nordic A/S Recombinant modified vaccinia virus ankara (mva) respiratory syncytial virus (rsv) vaccine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855224A (en) * 1984-03-09 1989-08-08 Genentech, Inc. Molecularly cloned diagnostic product and method of use
JPH01501357A (ja) * 1986-01-14 1989-05-18 ユニバ−シテイ・オブ・ノ−ス・カロライナ ヒト呼吸器系ウイルス用ワクチン
US5223254A (en) * 1987-09-29 1993-06-29 Praxis Biologics, Inc. Respiratory syncytial virus: vaccines
US5001230A (en) * 1988-02-18 1991-03-19 Schering Corporation T cell activation markers
SG106639A1 (en) * 2000-10-10 2004-10-29 Gen Electric Apparatus and method for introducing small amounts of refractory elements into a vapor deposition coating

Also Published As

Publication number Publication date
DK153290D0 (da) 1990-06-22
WO1989005823A1 (en) 1989-06-29
KR0137963B1 (ko) 1998-04-30
DE3878468D1 (de) 1993-03-25
FI102382B1 (fi) 1998-11-30
FI102382B (fi) 1998-11-30
KR900700508A (ko) 1990-08-13
JP2716503B2 (ja) 1998-02-18
NO902802D0 (no) 1990-06-22
DE3878468T2 (de) 1993-06-09
DK173175B1 (da) 2000-03-06
EP0396563A1 (en) 1990-11-14
EP0396563B1 (en) 1993-02-10
AU617739B2 (en) 1991-12-05
ATE85622T1 (de) 1993-02-15
US5194595A (en) 1993-03-16
JPH03501723A (ja) 1991-04-18
CA1320163C (en) 1993-07-13
AU2785089A (en) 1989-07-19
HK166295A (en) 1995-11-03
US5288630A (en) 1994-02-22
FI903154A0 (fi) 1990-06-21
NO902802L (no) 1990-06-22
MX9203458A (es) 1992-09-01
DK153290A (da) 1990-08-16

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