NO2707385T3 - - Google Patents
Info
- Publication number
- NO2707385T3 NO2707385T3 NO12722057A NO12722057A NO2707385T3 NO 2707385 T3 NO2707385 T3 NO 2707385T3 NO 12722057 A NO12722057 A NO 12722057A NO 12722057 A NO12722057 A NO 12722057A NO 2707385 T3 NO2707385 T3 NO 2707385T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161486005P | 2011-05-13 | 2011-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2707385T3 true NO2707385T3 (no) | 2018-02-17 |
Family
ID=46124783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO12722057A NO2707385T3 (no) | 2011-05-13 | 2012-05-14 |
Country Status (23)
| Country | Link |
|---|---|
| US (6) | US20140248314A1 (no) |
| EP (2) | EP2707385B1 (no) |
| JP (1) | JP2014519819A (no) |
| CN (1) | CN103842374A (no) |
| AU (1) | AU2012255971A1 (no) |
| BR (1) | BR112013029169B1 (no) |
| CA (1) | CA2835644C (no) |
| CY (2) | CY1119849T1 (no) |
| DK (2) | DK2707385T3 (no) |
| ES (2) | ES2651143T3 (no) |
| FR (1) | FR23C1046I1 (no) |
| HR (2) | HRP20171703T1 (no) |
| HU (2) | HUE034673T2 (no) |
| LT (2) | LT2707385T (no) |
| MX (1) | MX351011B (no) |
| NO (1) | NO2707385T3 (no) |
| PL (2) | PL3275892T3 (no) |
| PT (2) | PT3275892T (no) |
| RS (1) | RS56748B1 (no) |
| RU (1) | RU2013155485A (no) |
| SG (1) | SG194755A1 (no) |
| SI (2) | SI3275892T1 (no) |
| WO (1) | WO2012158613A1 (no) |
Families Citing this family (96)
| Publication number | Priority date | Publication date | Assignee | Title |
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| ES2563730T3 (es) | 2009-07-15 | 2016-03-16 | Glaxosmithkline Biologicals S.A. | Composiciones de proteína RSV F y procedimientos de fabricación de las mismas |
| LT3243526T (lt) | 2010-07-06 | 2020-02-10 | Glaxosmithkline Biologicals S.A. | Rnr pristatymas, skirtas keleto imuninio atsako paleidimui |
| JP5940064B2 (ja) | 2010-07-06 | 2016-06-29 | ノバルティス アーゲー | 低用量のｒｎａを用いた大型哺乳動物の免疫化 |
| BR112013000244A2 (pt) | 2010-07-06 | 2016-05-17 | Novartis Ag | lipossomas com lipídeos apresentando pka vantajoso para administração de rna |
| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| SI2611461T1 (sl) | 2010-08-31 | 2022-08-31 | Glaxosmithkline Biologicals Sa | Pegilirani liposomi za dostavo imunogen-kodirajoče RNA |
| CA2813466A1 (en) | 2010-10-01 | 2012-04-05 | Moderna Therapeutics, Inc. | Modified nucleosides, nucleotides, and nucleic acids that disrupt major groove binding partner interactions |
| AU2011316707A1 (en) | 2010-10-11 | 2013-05-09 | Novartis Ag | Antigen delivery platforms |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| ES2656050T3 (es) * | 2011-07-06 | 2018-02-22 | Glaxosmithkline Biologicals Sa | Composiciones de combinación inmunogénica y usos de las mismas |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| CN110511939A (zh) | 2011-10-03 | 2019-11-29 | 现代泰克斯公司 | 修饰的核苷、核苷酸和核酸及其用途 |
| EP2791160B1 (en) | 2011-12-16 | 2022-03-02 | ModernaTX, Inc. | Modified mrna compositions |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| EP2833923A4 (en) | 2012-04-02 | 2016-02-24 | Moderna Therapeutics Inc | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS |
| US9512456B2 (en) | 2012-08-14 | 2016-12-06 | Modernatx, Inc. | Enzymes and polymerases for the synthesis of RNA |
| PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
| MX2015008847A (es) * | 2013-01-10 | 2015-10-30 | Novartis Ag | Composiciones inmunogenicas de virus de influenza y usos de las mismas. |
| WO2014159813A1 (en) | 2013-03-13 | 2014-10-02 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
| US9738689B2 (en) | 2013-03-13 | 2017-08-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Prefusion RSV F proteins and their use |
| MX2015013065A (es) * | 2013-03-13 | 2016-06-06 | Us Health | Proteinas f de rsv de prefusion y su uso. |
| PL403149A1 (pl) * | 2013-03-14 | 2014-09-15 | Celon Pharma Spółka Akcyjna | Nowe związki pochodne pirazolilobenzo[d]imidazolu |
| EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| JP6506249B2 (ja) | 2013-03-14 | 2019-04-24 | エモリー ユニバーシティー | サイレント変異を有する組換えｒｓｖ、ワクチン、およびそれに関連する方法 |
| US9060975B2 (en) | 2013-03-14 | 2015-06-23 | Mucosis Bv | Heat-stable respiratory syncytial virus F protein oligomers and their use in immunological compositions |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| EA039803B1 (ru) | 2013-04-25 | 2022-03-15 | Янссен Вэксинс Энд Превеншн Б.В. | Стабилизированные растворимые f-полипептиды rsv до слияния |
| CA2914792C (en) * | 2013-06-17 | 2024-02-27 | Crucell Holland B.V. | Stabilized soluble pre-fusion rsv f polypeptides |
| JP6685903B2 (ja) * | 2013-07-25 | 2020-04-22 | アバター・メディカル・エルエルシー | 立体構造的に安定化されたｒｓｖ融合前ｆタンパク質 |
| US20150110825A1 (en) * | 2013-09-24 | 2015-04-23 | Massachusetts Institute Of Technology | Self-assembled nanoparticle vaccines |
| WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| SG11201602503TA (en) | 2013-10-03 | 2016-04-28 | Moderna Therapeutics Inc | Polynucleotides encoding low density lipoprotein receptor |
| EP2974739A1 (en) | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF trimerization domains |
| MX2016016533A (es) | 2014-06-13 | 2017-05-01 | Glaxosmithkline Biologicals Sa | Combinaciones inmunogenas. |
| BR112017005833A8 (pt) * | 2014-09-23 | 2023-02-14 | Merial Inc | Vacinas recombinantes fmdv e seus usos |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| US10420834B2 (en) | 2014-12-24 | 2019-09-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant metapneumovirus F proteins and their use |
| EP3247388A1 (en) | 2015-01-20 | 2017-11-29 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Recombinant human/bovine parainfluenza virus 3 (b/hpiv3) expressing a chimeric rsv/bpiv3 f protein and uses thereof |
| EP3319634B1 (en) | 2015-07-07 | 2019-08-21 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion rsv f polypeptides |
| DK3319633T3 (da) | 2015-07-07 | 2021-02-01 | Janssen Vaccines & Prevention Bv | Vaccine mod rsv |
| US11324816B2 (en) | 2015-08-31 | 2022-05-10 | Technovax, Inc. | Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine |
| JP6975709B2 (ja) * | 2015-09-02 | 2021-12-01 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 安定化したウイルスクラスｉ融合タンパク質 |
| EP3359670B2 (en) | 2015-10-05 | 2024-02-14 | ModernaTX, Inc. | Methods for therapeutic administration of messenger ribonucleic acid drugs |
| BR112018008708A2 (pt) * | 2015-10-29 | 2018-11-06 | Univ Emory | rsv quimérico, composições imunogênicas e métodos de uso |
| EP3393512A1 (en) | 2015-12-23 | 2018-10-31 | Pfizer Inc | Rsv f protein mutants |
| CN109069611B (zh) * | 2016-03-29 | 2022-11-04 | 美国政府(由卫生和人类服务部的部长所代表) | 取代修饰的融合前rsv f蛋白及其用途 |
| AU2017248021B2 (en) | 2016-04-05 | 2021-08-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F proteins |
| AU2017248018A1 (en) | 2016-04-05 | 2018-09-27 | Janssen Vaccines & Prevention B.V. | Vaccine against RSV |
| MX2018014699A (es) | 2016-05-30 | 2019-02-28 | Janssen Vaccines & Prevention Bv | Proteinas f de prefusion del vrs estabilizadas. |
| WO2017207477A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
| EP3518967A4 (en) * | 2016-10-03 | 2020-04-29 | University of Massachusetts | METHODS OF IMMUNIZING PRE-IMMUNE SUBJECTS AGAINST RESPIRATORY SYNCYTIAL VIRUS (RSV) |
| CN106397547A (zh) * | 2016-11-28 | 2017-02-15 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106518988A (zh) * | 2016-11-28 | 2017-03-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106749555A (zh) * | 2016-11-28 | 2017-05-31 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106432435A (zh) * | 2016-11-28 | 2017-02-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106432439A (zh) * | 2016-11-28 | 2017-02-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106432437A (zh) * | 2016-11-28 | 2017-02-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106432436A (zh) * | 2016-11-28 | 2017-02-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106749556A (zh) * | 2016-11-28 | 2017-05-31 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
| CN106432438A (zh) * | 2016-11-28 | 2017-02-22 | 烟台偌帝生物工程有限公司 | 一种牛呼吸道胞合体病毒抗原蛋白 |
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| CN108265079A (zh) * | 2017-01-02 | 2018-07-10 | 刘昕 | 一种新型呼吸道合胞体病毒pre-F融合蛋白载体的制备方法 |
| WO2018170260A1 (en) | 2017-03-15 | 2018-09-20 | Modernatx, Inc. | Respiratory syncytial virus vaccine |
| US20200030432A1 (en) * | 2017-03-17 | 2020-01-30 | Modernatx, Inc. | Zoonotic disease rna vaccines |
| JP7291398B2 (ja) * | 2017-03-30 | 2023-06-15 | ザ ユニバーシティー オブ クイーンズランド | キメラ分子およびその使用 |
| CN115947873A (zh) | 2017-04-04 | 2023-04-11 | 华盛顿大学 | 显示副粘病毒和/或肺炎病毒f蛋白的自组装蛋白纳米结构及其用途 |
| CN110612116A (zh) | 2017-05-08 | 2019-12-24 | 磨石肿瘤生物技术公司 | 甲病毒新抗原载体 |
| AU2018269319A1 (en) | 2017-05-15 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Stable virus-containing composition |
| JP7406377B2 (ja) | 2017-05-15 | 2023-12-27 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | 安定なウイルス含有組成物 |
| AU2018267971A1 (en) | 2017-05-17 | 2019-11-07 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against RSV infection |
| BR112019025193A2 (pt) | 2017-05-30 | 2020-06-23 | Glaxosmithkline Biologicals S.A. | Métodos de fabricação de um adjuvante lipossomal, de fabricação de um concentrado lipossomal, para a preparação de uma composição imunogênica com adjuvante e para a preparação de uma solução, adjuvante lipossomal, composição imunogênica com adjuvante, e, solução |
| CN110891592A (zh) * | 2017-06-14 | 2020-03-17 | 维罗米蒂克斯股份公司 | 用于保护免受呼吸道合胞病毒的环状肽 |
| WO2019032480A1 (en) | 2017-08-07 | 2019-02-14 | Avatar Medical, Llc | PROTEINS F PRE-FUSION OF RSV STABILIZED IN TERMS OF CONFORMATION |
| WO2019053109A1 (en) | 2017-09-15 | 2019-03-21 | Janssen Vaccines & Prevention B.V. | METHOD FOR SAFE INDUCTION OF IMMUNITY AGAINST RSV |
| EP3717001A1 (en) | 2017-12-01 | 2020-10-07 | GlaxoSmithKline Biologicals S.A. | Saponin purification |
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| US11623004B2 (en) * | 2018-03-16 | 2023-04-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Compositions and methods for vaccination against respiratory syncytial virus infection |
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| CN109851678A (zh) * | 2019-03-07 | 2019-06-07 | 苏州宇之波生物科技有限公司 | 一种改良的亚稳定态牛呼吸道合胞病毒融合前体f蛋白质及编码的dna分子和其应用 |
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| BR112021024363A2 (pt) | 2019-06-05 | 2022-03-22 | Glaxosmithkline Biologicals Sa | Purificação de saponina |
| CN114502572A (zh) | 2019-09-04 | 2022-05-13 | 华盛顿大学 | 展示副粘病毒和/或肺炎病毒f蛋白的自组装蛋白纳米结构及其用途 |
| WO2021253172A1 (zh) * | 2020-06-15 | 2021-12-23 | 上海市公共卫生临床中心 | 利用受体识别域诱导抗新冠病毒中和抗体的方法 |
| CN113801206A (zh) * | 2020-06-15 | 2021-12-17 | 上海市公共卫生临床中心 | 利用受体识别域诱导抗新冠病毒中和抗体的方法 |
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| WO2022135563A1 (zh) * | 2020-12-24 | 2022-06-30 | 上海市公共卫生临床中心 | 同时诱导抗多种病毒的免疫应答的方法 |
| KR20230147156A (ko) | 2021-02-19 | 2023-10-20 | 얀센 백신스 앤드 프리벤션 비.브이. | 안정화된 융합 전 rsv fb 항원 |
| WO2023069887A1 (en) * | 2021-10-18 | 2023-04-27 | Yang, Kejian | Mucosal vaccine, methods of use and administration thereof |
| EP4169513A1 (en) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant composition comprising sting agonists |
| CN117586359A (zh) * | 2024-01-19 | 2024-02-23 | 北京安百胜生物科技有限公司 | 一种具有免疫原性的呼吸道合胞病毒（rsv）多肽 |
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